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The map label for this gene is yexA [H]

Identifier: 229917948

GI number: 229917948

Start: 2174469

End: 2174711

Strand: Direct

Name: yexA [H]

Synonym: EAT1b_2227

Alternate gene names: 229917948

Gene position: 2174469-2174711 (Clockwise)

Preceding gene: 229917947

Following gene: 229917949

Centisome position: 72.48

GC content: 46.09

Gene sequence:

>243_bases
ATGAAAAAAGTAAATGTGTATGTGACATTACGTGAAAGTGTACTCGACCCACAAGGAGTGGCCGTAAAAGGCGGACTCGA
ACATCTTGGATTCGCTGGAGTTGAATCGGTGCGCATCGGGAAAGTCATCGAGCTTCGAGTAGCGGACGACACGACAGAAG
ACATGGTCAAAGAAATGTGTGAGAAGTTACTCGTCAATACGGTCATTGAGAATTATGAAATCGAGATGGGGGTACTCGCA
TGA

Upstream 100 bases:

>100_bases
AAACGAAACAAAAGCTTGATAAAGATGTATTCCGTCGCGATTTAGGTTCTTTGACTGAGACGTATGGACAATTGTTAACA
CGCATAGGGGGAAACGGACA

Downstream 100 bases:

>100_bases
AGTTTGCGGTCATCGTCTTTCCAGGATCAAACTGTGACCTCGACATGTACCACGCGGTAAAAGATGTGCTCGGGGAAGAA
GCGGAATACGTGTTCCATAC

Product: phosphoribosylformylglycinamidine synthase, purS

Products: ADP; phosphate; 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 80; Mature: 80

Protein sequence:

>80_residues
MKKVNVYVTLRESVLDPQGVAVKGGLEHLGFAGVESVRIGKVIELRVADDTTEDMVKEMCEKLLVNTVIENYEIEMGVLA

Sequences:

>Translated_80_residues
MKKVNVYVTLRESVLDPQGVAVKGGLEHLGFAGVESVRIGKVIELRVADDTTEDMVKEMCEKLLVNTVIENYEIEMGVLA
>Mature_80_residues
MKKVNVYVTLRESVLDPQGVAVKGGLEHLGFAGVESVRIGKVIELRVADDTTEDMVKEMCEKLLVNTVIENYEIEMGVLA

Specific function: Unknown

COG id: COG1828

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0062 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003850
- ProDom:   PD010362 [H]

Pfam domain/function: PF02700 PurS [H]

EC number: 6.3.5.3

Molecular weight: Translated: 8821; Mature: 8821

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVNVYVTLRESVLDPQGVAVKGGLEHLGFAGVESVRIGKVIELRVADDTTEDMVKEMC
CCEEEEEEEEECCCCCCCCEEEECCCCCCCCCCCCCEECCEEEEEEECCCCHHHHHHHHH
EKLLVNTVIENYEIEMGVLA
HHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure
MKKVNVYVTLRESVLDPQGVAVKGGLEHLGFAGVESVRIGKVIELRVADDTTEDMVKEMC
CCEEEEEEEEECCCCCCCCEEEECCCCCCCCCCCCCEECCEEEEEEECCCCHHHHHHHHH
EKLLVNTVIENYEIEMGVLA
HHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide; L-glutamine; H2O

Specific reaction: ATP + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H2O = ADP + phosphate + 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3036807; 9384377 [H]