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The map label for this gene is macB [H]

Identifier: 229917889

GI number: 229917889

Start: 2104079

End: 2105233

Strand: Direct

Name: macB [H]

Synonym: EAT1b_2167

Alternate gene names: 229917889

Gene position: 2104079-2105233 (Clockwise)

Preceding gene: 229917888

Following gene: 229917890

Centisome position: 70.14

GC content: 52.03

Gene sequence:

>1155_bases
ATGATTCGAGAAAATATACGCATGGCTTGGTTGACGGTCATCAGTCACAAGATGCGCTCCTTCTTGACGATTTTAGGGAT
TGTCATCGGGACGGCTTCGATTATTGCCTTGATGACGATCATTTCCGGTGTGACCGATTCCATTAACGATGAAGTCGCGA
CGTTTGGAGCTGATCGTATGACCGTTCAAATCGGAGAAGATGGGAAATCCGGTGTCAGTATGGCGGACATGGATCGGCTC
GAAGCCATTGAAGGGATCGCCTCACTCTCTCCGACGCTGAGTCAAATGACCGATGTATATGTAGCGGGGCAGACGGAACA
ACAAACCATTCTTGGGAAAAGTGAAGCGTTCTTCAAAGACGATTCGGTTGTCGCAACCGGGCGCGGATTGACACCACTCG
ACGTCAATCAACAGACGCGTGTCGCCTTGCTCGGAGAAACGATTGCGAAAGAGGCGTTTCCGACATCCTCTCCTCTCGGG
GAAGAGATTTCCGTTGGTGGGATTCGTTACACCGTCGTTGGAACGCTTGCGCCATCATCGGAATTTTCCATGTCGACAGA
CGAGGCCATCGTCATCCCTGTGACGACTGCACTGACGCAGTTTCATCAAGGGACGATTGCCACGTTTGATTTATATACCG
AACCGGGTGCTTCAGCTGTCGTACAGGATGAAGTGACACAACAGCTGACGACCGCGTTCAATGGACGTGACGCCTTTACA
GTGACGAGCTTTGAGGACGCACTCGCTTCCATCGATCAAATCAATGCGCTGCTCAGCATGCTCCTCGTCGGCATCGCTTC
GATTTCTTTACTCGTCGGAGGCATCGGCATCATGAACATGATGCTCGTTTCGGTGACCGAACGAACAAGCGAGATCGGAC
TGCGTAAAGCACTCGGTGCGACACCTGGTAAGATTCGACAACAGTTCTTGTTTGAGTCCGTCCTGCTTTCGATGCTCGGA
GGGCTCGTCGGTGTCTTGATTGGCGGACTGCTTGCCTTCGGACTGACGCTCGTCATGGGCGTACCGTTCACATTGGCAAG
TTCAACTGTCGGATTGGCACTCGGTTTCTCTGTCGTAATCGGGGTCGTGTTCGGCTATATTCCAGCTCGGAAAGCCTCGA
ACTTGCAACCGATTGAAGCGTTGCGAAACGTATAA

Upstream 100 bases:

>100_bases
AGACAATTATCATGATCACCCATGATATCGATATCGCCAAAGAAGCGACTCGTATCGTACATGTGCGTGACGGGAAGATT
GAAAAGGAGGAACGGGTGCG

Downstream 100 bases:

>100_bases
GCCATTAGAAAGAAGGGAAACAACATGGTCACCATTTTACTCGCAGAAGATGATGAGACGCTCGGCGGTTTATTAGTCGA
TTATTTGACGGTGGCCGGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MIRENIRMAWLTVISHKMRSFLTILGIVIGTASIIALMTIISGVTDSINDEVATFGADRMTVQIGEDGKSGVSMADMDRL
EAIEGIASLSPTLSQMTDVYVAGQTEQQTILGKSEAFFKDDSVVATGRGLTPLDVNQQTRVALLGETIAKEAFPTSSPLG
EEISVGGIRYTVVGTLAPSSEFSMSTDEAIVIPVTTALTQFHQGTIATFDLYTEPGASAVVQDEVTQQLTTAFNGRDAFT
VTSFEDALASIDQINALLSMLLVGIASISLLVGGIGIMNMMLVSVTERTSEIGLRKALGATPGKIRQQFLFESVLLSMLG
GLVGVLIGGLLAFGLTLVMGVPFTLASSTVGLALGFSVVIGVVFGYIPARKASNLQPIEALRNV

Sequences:

>Translated_384_residues
MIRENIRMAWLTVISHKMRSFLTILGIVIGTASIIALMTIISGVTDSINDEVATFGADRMTVQIGEDGKSGVSMADMDRL
EAIEGIASLSPTLSQMTDVYVAGQTEQQTILGKSEAFFKDDSVVATGRGLTPLDVNQQTRVALLGETIAKEAFPTSSPLG
EEISVGGIRYTVVGTLAPSSEFSMSTDEAIVIPVTTALTQFHQGTIATFDLYTEPGASAVVQDEVTQQLTTAFNGRDAFT
VTSFEDALASIDQINALLSMLLVGIASISLLVGGIGIMNMMLVSVTERTSEIGLRKALGATPGKIRQQFLFESVLLSMLG
GLVGVLIGGLLAFGLTLVMGVPFTLASSTVGLALGFSVVIGVVFGYIPARKASNLQPIEALRNV
>Mature_384_residues
MIRENIRMAWLTVISHKMRSFLTILGIVIGTASIIALMTIISGVTDSINDEVATFGADRMTVQIGEDGKSGVSMADMDRL
EAIEGIASLSPTLSQMTDVYVAGQTEQQTILGKSEAFFKDDSVVATGRGLTPLDVNQQTRVALLGETIAKEAFPTSSPLG
EEISVGGIRYTVVGTLAPSSEFSMSTDEAIVIPVTTALTQFHQGTIATFDLYTEPGASAVVQDEVTQQLTTAFNGRDAFT
VTSFEDALASIDQINALLSMLLVGIASISLLVGGIGIMNMMLVSVTERTSEIGLRKALGATPGKIRQQFLFESVLLSMLG
GLVGVLIGGLLAFGLTLVMGVPFTLASSTVGLALGFSVVIGVVFGYIPARKASNLQPIEALRNV

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=393, Percent_Identity=30.2798982188295, Blast_Score=151, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 40422; Mature: 40422

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRENIRMAWLTVISHKMRSFLTILGIVIGTASIIALMTIISGVTDSINDEVATFGADRM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEE
TVQIGEDGKSGVSMADMDRLEAIEGIASLSPTLSQMTDVYVAGQTEQQTILGKSEAFFKD
EEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHEEEECCCHHHHHHCCCHHHCCC
DSVVATGRGLTPLDVNQQTRVALLGETIAKEAFPTSSPLGEEISVGGIRYTVVGTLAPSS
CCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCC
EFSMSTDEAIVIPVTTALTQFHQGTIATFDLYTEPGASAVVQDEVTQQLTTAFNGRDAFT
CCCCCCCCEEEEEHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEE
VTSFEDALASIDQINALLSMLLVGIASISLLVGGIGIMNMMLVSVTERTSEIGLRKALGA
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TPGKIRQQFLFESVLLSMLGGLVGVLIGGLLAFGLTLVMGVPFTLASSTVGLALGFSVVI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GVVFGYIPARKASNLQPIEALRNV
HHHHHHCCCCCCCCCCHHHHHHCC
>Mature Secondary Structure
MIRENIRMAWLTVISHKMRSFLTILGIVIGTASIIALMTIISGVTDSINDEVATFGADRM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEE
TVQIGEDGKSGVSMADMDRLEAIEGIASLSPTLSQMTDVYVAGQTEQQTILGKSEAFFKD
EEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHEEEECCCHHHHHHCCCHHHCCC
DSVVATGRGLTPLDVNQQTRVALLGETIAKEAFPTSSPLGEEISVGGIRYTVVGTLAPSS
CCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCC
EFSMSTDEAIVIPVTTALTQFHQGTIATFDLYTEPGASAVVQDEVTQQLTTAFNGRDAFT
CCCCCCCCEEEEEHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEE
VTSFEDALASIDQINALLSMLLVGIASISLLVGGIGIMNMMLVSVTERTSEIGLRKALGA
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TPGKIRQQFLFESVLLSMLGGLVGVLIGGLLAFGLTLVMGVPFTLASSTVGLALGFSVVI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GVVFGYIPARKASNLQPIEALRNV
HHHHHHCCCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA