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The map label for this gene is argS

Identifier: 229917757

GI number: 229917757

Start: 1988661

End: 1990343

Strand: Direct

Name: argS

Synonym: EAT1b_2035

Alternate gene names: 229917757

Gene position: 1988661-1990343 (Clockwise)

Preceding gene: 229917754

Following gene: 229917760

Centisome position: 66.29

GC content: 50.51

Gene sequence:

>1683_bases
ATGAGTTATGAACGCAAGTATGCAGAAGCACTATCCCGTGTCATCGGTGAAGAACTCACGATTGACCAAATTGAAGCCTT
GATTGAGAAGCCAAAACACGAGGCGCACGGTGACCTCGCGTTCCCGTGTTTCCAATTGGCGAAAGCTTACCGGAAAGCAC
CTGTCATGATTGCGACAGATATCGCAAATGAATTGAACGATGAATTGTTCACGAAAGTGGAGGCGGCAGGACCTTACGTC
AACGTCTTCTTGAGCCGTGATGTCGTATCAAAAGAAATCATCAACACGGTGCTTGAGGAAAAATCAGAGTATGCAACACA
CGAGGCACGCAATGAAACGATTGTGACGGACTTCTCGTCACCAAACATTGCGAAGCCGTTCTCGATGGGTCACTTGCGTT
CGACGGTGATTGGGAATGCAATCAACCAAATCGCACGTAAAAACGGATATGACGTCGTCGGCGTCAACCACCTTGGAGAC
TGGGGCACTCAGTTTGGGAAATTGATGGTCGCCTACAAGAAGTGGGGCGATGAGGAAGCGGTACGCGCCAATCCAATCGC
AGAACTCTTGAAATTATACGTCCATTTCCACGAAGAGGCGAAGACACAACCAGAACTCGAAGACGAAGGCCGTGCTTGGT
TCAAAAAGCTTGAAGATGGTGATGCGGAAGCGACAGAGCTTTGGCAGTGGTTCCGTGACGAGTCGCTCAAAGAGTTCCAG
AAAGTATATGACCTTCTTGGAGTGAAATTCGAAAGCTTCAACGGGGAAGCGTTCTATAACGATAAAATGGGACGCGTCGT
CGAGATGCTAGAAGCGAAAAACCTCTTAGTGGAAAGTGAAGGGGCGATGGTCGTCTCGCTCGAAGAGGAGAACTTGCCAC
CTTGCTTGATCAAGAAAAAAGATGGCGCGACGTTGTACGCGACACGTGATTTGGCAGCGGCAATCTATCGTTACGAGACG
TACAACTTCGTTCAAGCAAACTATGTCGTCGGTGGCGAACAGGCGCTCCATTTCAAACAACTCTTCTCGGTCCTTCGTAA
GCTTGGATATGACTTTGTTGATGGCATGCATCACGTGCCGTTCGGCTTGATCTTGCAAGAAGGGAAGAAGATGTCGACAC
GTAAAGGACGCATCGTCCTTCTTGAGGAAGTCTTGAAAGAGGCGATCGAGAAAGCGCAGGCGAATATCGAGCAGAAGAAT
CCGGATCTTGCGAACGCACAAGACGTTGCCCGCATGGTCGGTGTCGGCGCGGTCGTCTTCCACGACTTGAAGAACGAACG
CATCAACAACATCGAGTTCGATCTCGACAGCATGCTCAAGTTTGAAGGGGAGACAGGACCTTACGTCCAATACACGAACG
CTCGTGCGAATTCACTCCTCCGTAAAGGAAACTATGACGGCTCACCATTCACTGGTGCAGACGATGATTACTCATGGGGT
GTCGTCACGATGCTCAACGCGTTCCCGCACGTCATCACGCGTGCACATGAACGCCGCGAACCATCCATCATCAGCCGCTA
TGTACTCGACCTCGCGCAAGCGTTCAACAAGTATTACGGCCATGTCCGTGTCTTAGAAGAAGATGCAGGCAAACAATCAC
GCCTCGCGCTCGTGAAGGCCGTGACGCTCGTATTGACAGAAGGGCTCCGTTTACTCGGTGTCGAAGCGCCTGAAGAAATG
TAA

Upstream 100 bases:

>100_bases
TGCAGGCAAGAAGAGTGGTACCGCGGGAATTCCCGTCTCTTTGCATCTATGCAAAGGGCGTTTTTTTTATGAGTTGTTAT
TGAAGAAGGAGGACATACAG

Downstream 100 bases:

>100_bases
GACAGACGAAAGGACCTCAAAAAATTGAGGTCCTTTTTGTATTCACGCTTTCATCCGCGTCACCGTCCGGGCTTCCGTAT
CATAGAGACACCATTCCCGA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MSYERKYAEALSRVIGEELTIDQIEALIEKPKHEAHGDLAFPCFQLAKAYRKAPVMIATDIANELNDELFTKVEAAGPYV
NVFLSRDVVSKEIINTVLEEKSEYATHEARNETIVTDFSSPNIAKPFSMGHLRSTVIGNAINQIARKNGYDVVGVNHLGD
WGTQFGKLMVAYKKWGDEEAVRANPIAELLKLYVHFHEEAKTQPELEDEGRAWFKKLEDGDAEATELWQWFRDESLKEFQ
KVYDLLGVKFESFNGEAFYNDKMGRVVEMLEAKNLLVESEGAMVVSLEEENLPPCLIKKKDGATLYATRDLAAAIYRYET
YNFVQANYVVGGEQALHFKQLFSVLRKLGYDFVDGMHHVPFGLILQEGKKMSTRKGRIVLLEEVLKEAIEKAQANIEQKN
PDLANAQDVARMVGVGAVVFHDLKNERINNIEFDLDSMLKFEGETGPYVQYTNARANSLLRKGNYDGSPFTGADDDYSWG
VVTMLNAFPHVITRAHERREPSIISRYVLDLAQAFNKYYGHVRVLEEDAGKQSRLALVKAVTLVLTEGLRLLGVEAPEEM

Sequences:

>Translated_560_residues
MSYERKYAEALSRVIGEELTIDQIEALIEKPKHEAHGDLAFPCFQLAKAYRKAPVMIATDIANELNDELFTKVEAAGPYV
NVFLSRDVVSKEIINTVLEEKSEYATHEARNETIVTDFSSPNIAKPFSMGHLRSTVIGNAINQIARKNGYDVVGVNHLGD
WGTQFGKLMVAYKKWGDEEAVRANPIAELLKLYVHFHEEAKTQPELEDEGRAWFKKLEDGDAEATELWQWFRDESLKEFQ
KVYDLLGVKFESFNGEAFYNDKMGRVVEMLEAKNLLVESEGAMVVSLEEENLPPCLIKKKDGATLYATRDLAAAIYRYET
YNFVQANYVVGGEQALHFKQLFSVLRKLGYDFVDGMHHVPFGLILQEGKKMSTRKGRIVLLEEVLKEAIEKAQANIEQKN
PDLANAQDVARMVGVGAVVFHDLKNERINNIEFDLDSMLKFEGETGPYVQYTNARANSLLRKGNYDGSPFTGADDDYSWG
VVTMLNAFPHVITRAHERREPSIISRYVLDLAQAFNKYYGHVRVLEEDAGKQSRLALVKAVTLVLTEGLRLLGVEAPEEM
>Mature_559_residues
SYERKYAEALSRVIGEELTIDQIEALIEKPKHEAHGDLAFPCFQLAKAYRKAPVMIATDIANELNDELFTKVEAAGPYVN
VFLSRDVVSKEIINTVLEEKSEYATHEARNETIVTDFSSPNIAKPFSMGHLRSTVIGNAINQIARKNGYDVVGVNHLGDW
GTQFGKLMVAYKKWGDEEAVRANPIAELLKLYVHFHEEAKTQPELEDEGRAWFKKLEDGDAEATELWQWFRDESLKEFQK
VYDLLGVKFESFNGEAFYNDKMGRVVEMLEAKNLLVESEGAMVVSLEEENLPPCLIKKKDGATLYATRDLAAAIYRYETY
NFVQANYVVGGEQALHFKQLFSVLRKLGYDFVDGMHHVPFGLILQEGKKMSTRKGRIVLLEEVLKEAIEKAQANIEQKNP
DLANAQDVARMVGVGAVVFHDLKNERINNIEFDLDSMLKFEGETGPYVQYTNARANSLLRKGNYDGSPFTGADDDYSWGV
VTMLNAFPHVITRAHERREPSIISRYVLDLAQAFNKYYGHVRVLEEDAGKQSRLALVKAVTLVLTEGLRLLGVEAPEEM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI197100773, Length=547, Percent_Identity=33.6380255941499, Blast_Score=313, Evalue=3e-85,
Organism=Homo sapiens, GI15149476, Length=531, Percent_Identity=30.8851224105461, Blast_Score=235, Evalue=7e-62,
Organism=Escherichia coli, GI1788184, Length=548, Percent_Identity=35.2189781021898, Blast_Score=285, Evalue=7e-78,
Organism=Caenorhabditis elegans, GI71985061, Length=534, Percent_Identity=29.4007490636704, Blast_Score=199, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI71985068, Length=499, Percent_Identity=29.8597194388778, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17532153, Length=487, Percent_Identity=27.1047227926078, Blast_Score=161, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6320548, Length=579, Percent_Identity=33.5060449050086, Blast_Score=331, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6321883, Length=559, Percent_Identity=33.9892665474061, Blast_Score=328, Evalue=9e-91,
Organism=Drosophila melanogaster, GI28571570, Length=469, Percent_Identity=32.6226012793177, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI18859963, Length=544, Percent_Identity=28.4926470588235, Blast_Score=211, Evalue=1e-54,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_EXISA (C4L0Z5)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002886403.1
- ProteinModelPortal:   C4L0Z5
- GeneID:   7868842
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_2035
- OMA:   AYKKWGN
- ProtClustDB:   PRK12451
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63312; Mature: 63180

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYERKYAEALSRVIGEELTIDQIEALIEKPKHEAHGDLAFPCFQLAKAYRKAPVMIATD
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEHH
IANELNDELFTKVEAAGPYVNVFLSRDVVSKEIINTVLEEKSEYATHEARNETIVTDFSS
HHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
PNIAKPFSMGHLRSTVIGNAINQIARKNGYDVVGVNHLGDWGTQFGKLMVAYKKWGDEEA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCC
VRANPIAELLKLYVHFHEEAKTQPELEDEGRAWFKKLEDGDAEATELWQWFRDESLKEFQ
CCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KVYDLLGVKFESFNGEAFYNDKMGRVVEMLEAKNLLVESEGAMVVSLEEENLPPCLIKKK
HHHHHHCCEEECCCCCEEECCHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCEEEEEC
DGATLYATRDLAAAIYRYETYNFVQANYVVGGEQALHFKQLFSVLRKLGYDFVDGMHHVP
CCCEEEEHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHHHHHHHHHHCCHHHCCCCCCC
FGLILQEGKKMSTRKGRIVLLEEVLKEAIEKAQANIEQKNPDLANAQDVARMVGVGAVVF
HHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
HDLKNERINNIEFDLDSMLKFEGETGPYVQYTNARANSLLRKGNYDGSPFTGADDDYSWG
HHHHCCCCCCCEECHHHHHHCCCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCH
VVTMLNAFPHVITRAHERREPSIISRYVLDLAQAFNKYYGHVRVLEEDAGKQSRLALVKA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHH
VTLVLTEGLRLLGVEAPEEM
HHHHHHCCHHEEECCCCCCC
>Mature Secondary Structure 
SYERKYAEALSRVIGEELTIDQIEALIEKPKHEAHGDLAFPCFQLAKAYRKAPVMIATD
CCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEHH
IANELNDELFTKVEAAGPYVNVFLSRDVVSKEIINTVLEEKSEYATHEARNETIVTDFSS
HHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
PNIAKPFSMGHLRSTVIGNAINQIARKNGYDVVGVNHLGDWGTQFGKLMVAYKKWGDEEA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCC
VRANPIAELLKLYVHFHEEAKTQPELEDEGRAWFKKLEDGDAEATELWQWFRDESLKEFQ
CCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KVYDLLGVKFESFNGEAFYNDKMGRVVEMLEAKNLLVESEGAMVVSLEEENLPPCLIKKK
HHHHHHCCEEECCCCCEEECCHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCEEEEEC
DGATLYATRDLAAAIYRYETYNFVQANYVVGGEQALHFKQLFSVLRKLGYDFVDGMHHVP
CCCEEEEHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHHHHHHHHHHCCHHHCCCCCCC
FGLILQEGKKMSTRKGRIVLLEEVLKEAIEKAQANIEQKNPDLANAQDVARMVGVGAVVF
HHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
HDLKNERINNIEFDLDSMLKFEGETGPYVQYTNARANSLLRKGNYDGSPFTGADDDYSWG
HHHHCCCCCCCEECHHHHHHCCCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCH
VVTMLNAFPHVITRAHERREPSIISRYVLDLAQAFNKYYGHVRVLEEDAGKQSRLALVKA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHH
VTLVLTEGLRLLGVEAPEEM
HHHHHHCCHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA