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The map label for this gene is ung [H]

Identifier: 229917731

GI number: 229917731

Start: 1960349

End: 1961026

Strand: Direct

Name: ung [H]

Synonym: EAT1b_2008

Alternate gene names: 229917731

Gene position: 1960349-1961026 (Clockwise)

Preceding gene: 229917730

Following gene: 229917732

Centisome position: 65.35

GC content: 45.72

Gene sequence:

>678_bases
ATGGCAGATCAGTTATCGAGTCGATTACTTGGAGATTGGACGGATATTATCCGAGAAGAGATGAAACAACCTTACTTTCA
ACAATTAAAGCAATTCGTTGACCAAGCGTATGAAGAAACGATCGTTTACCCGACCCGGGAAGATATTTGGAACGCATTTA
TTCACACAAAATTTAGTGGAGTGAAGTGCGTCATTTTAGGGCAAGATCCGTACCACGGACCGAATCAAGCGCATGGACTC
AGTTTTTCGGTGCAGGACGGGGTTCGTTTCCCACCGTCTCTACGAAACATCTTTCAAGAACTAAAAGATGACGTTGGATG
TGATCTCCCGAAGAGTGGCAATCTCGAGAAATGGGCGAAACAAGGCGTCCTTCTCTTAAATACGGCACTGACGGTTGAAG
CGGGAAAGGCGGGCTCTCACCGTGGAAAAGGATGGGAACAGTTCACTGATTCCATCATTGAGCGGCTCGGGAGTCGTGAG
GAACCGATTGTATTCATCTTGTGGGGAAATGATGCGAAGAAGAAAATGAAATGGATTGGAGACCAACATAAAGTGCTCAC
GTCGGTACATCCAAGTCCTTTGTCATCCCATCGTGGATTCTTCGGTTCTAAGCCATTCTCCAAAGTAAACGATACATTGA
AGGAGTGGGGAAAACCCCCAATTGAATGGTGTTTATGA

Upstream 100 bases:

>100_bases
CAGGCGCCGTAACGGTATAACCTAGAGAGACGAGTCGACTGACTCGTCTTTTTGTATGCATTCATTTTGGGTATGATACA
AAGGGAAAGGGGAGTATGCA

Downstream 100 bases:

>100_bases
CAGTCTACGAAATTTCGTAGGCTGTTTTTTGTTGACGCGTTGAAAAACCTTTGGTACAGTAACTAACAAGACGTCACTTT
AGTGCTTAAAAGCATATATG

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MADQLSSRLLGDWTDIIREEMKQPYFQQLKQFVDQAYEETIVYPTREDIWNAFIHTKFSGVKCVILGQDPYHGPNQAHGL
SFSVQDGVRFPPSLRNIFQELKDDVGCDLPKSGNLEKWAKQGVLLLNTALTVEAGKAGSHRGKGWEQFTDSIIERLGSRE
EPIVFILWGNDAKKKMKWIGDQHKVLTSVHPSPLSSHRGFFGSKPFSKVNDTLKEWGKPPIEWCL

Sequences:

>Translated_225_residues
MADQLSSRLLGDWTDIIREEMKQPYFQQLKQFVDQAYEETIVYPTREDIWNAFIHTKFSGVKCVILGQDPYHGPNQAHGL
SFSVQDGVRFPPSLRNIFQELKDDVGCDLPKSGNLEKWAKQGVLLLNTALTVEAGKAGSHRGKGWEQFTDSIIERLGSRE
EPIVFILWGNDAKKKMKWIGDQHKVLTSVHPSPLSSHRGFFGSKPFSKVNDTLKEWGKPPIEWCL
>Mature_224_residues
ADQLSSRLLGDWTDIIREEMKQPYFQQLKQFVDQAYEETIVYPTREDIWNAFIHTKFSGVKCVILGQDPYHGPNQAHGLS
FSVQDGVRFPPSLRNIFQELKDDVGCDLPKSGNLEKWAKQGVLLLNTALTVEAGKAGSHRGKGWEQFTDSIIERLGSREE
PIVFILWGNDAKKKMKWIGDQHKVLTSVHPSPLSSHRGFFGSKPFSKVNDTLKEWGKPPIEWCL

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=214, Percent_Identity=49.0654205607477, Blast_Score=198, Evalue=3e-51,
Organism=Homo sapiens, GI6224979, Length=214, Percent_Identity=49.0654205607477, Blast_Score=198, Evalue=4e-51,
Organism=Escherichia coli, GI1788934, Length=227, Percent_Identity=49.3392070484581, Blast_Score=218, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17556304, Length=226, Percent_Identity=46.0176991150442, Blast_Score=184, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6323620, Length=231, Percent_Identity=44.5887445887446, Blast_Score=178, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 25626; Mature: 25495

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS00019 ACTININ_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADQLSSRLLGDWTDIIREEMKQPYFQQLKQFVDQAYEETIVYPTREDIWNAFIHTKFSG
CCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
VKCVILGQDPYHGPNQAHGLSFSVQDGVRFPPSLRNIFQELKDDVGCDLPKSGNLEKWAK
EEEEEECCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
QGVLLLNTALTVEAGKAGSHRGKGWEQFTDSIIERLGSREEPIVFILWGNDAKKKMKWIG
CCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHC
DQHKVLTSVHPSPLSSHRGFFGSKPFSKVNDTLKEWGKPPIEWCL
CHHHHHHHCCCCCCHHCCCCCCCCCHHHHHHHHHHHCCCCHHHCC
>Mature Secondary Structure 
ADQLSSRLLGDWTDIIREEMKQPYFQQLKQFVDQAYEETIVYPTREDIWNAFIHTKFSG
CHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
VKCVILGQDPYHGPNQAHGLSFSVQDGVRFPPSLRNIFQELKDDVGCDLPKSGNLEKWAK
EEEEEECCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
QGVLLLNTALTVEAGKAGSHRGKGWEQFTDSIIERLGSREEPIVFILWGNDAKKKMKWIG
CCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHC
DQHKVLTSVHPSPLSSHRGFFGSKPFSKVNDTLKEWGKPPIEWCL
CHHHHHHHCCCCCCHHCCCCCCCCCHHHHHHHHHHHCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA