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The map label for this gene is moaC [H]

Identifier: 229917641

GI number: 229917641

Start: 1877891

End: 1878355

Strand: Direct

Name: moaC [H]

Synonym: EAT1b_1917

Alternate gene names: 229917641

Gene position: 1877891-1878355 (Clockwise)

Preceding gene: 229917640

Following gene: 229917642

Centisome position: 62.6

GC content: 54.84

Gene sequence:

>465_bases
ATGGAACTGACACACATGAACGACCAAGGGCGGGCGCGGATGGTCGATGTCTCGGATAAACCGGAAACGACACGGACAGC
TCGGGCCCGCACATCAGTTGAATTGAGCAGTGAACTGAAACAGCTCATCACGGATGGTGACCTTGCGAAAGGCGACGTGC
TTGCTGTCGCCCAAGTGGCCGGGATTATGGCCGCCAAAGAGACGAGCCGCATCATCCCGATGTGTCACCCGCTCGCCTTG
AAAAAAGTCGATTTAACATTCGAATGGGACGAGACACAGCTCATCATCGAGTCGTTCGTGAAGACGAAAGGTGATACCGG
TGTTGAGATGGAAGCGTTGACGGCCGCATCGGTCGCAGCGTTGACCGTATACGATATGACGAAAGCGGTCGATAAAGGCA
TCGTCATCGGGCCGACATACTTGCTTGAGAAACAAGGCGGGAAGTCAGGGGACTACGTCCGATGA

Upstream 100 bases:

>100_bases
TCTCATGTTCGCGGTCAATGAGCGCTATGAGACGGACGAATATACGGTTGCAGACGGAGACACGGTCGCCGTCATTCCAA
TGGTGAGCGGAGGATAAACG

Downstream 100 bases:

>100_bases
CACATGTTCCGGAACGTTACGCGCGGCAGGCCCGGTTCCACGGTATCGGTGGGGACGGGCAAGAACGTCTGATGGTGAAA
CGAGTGCTCGTCGTCGGTCT

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MELTHMNDQGRARMVDVSDKPETTRTARARTSVELSSELKQLITDGDLAKGDVLAVAQVAGIMAAKETSRIIPMCHPLAL
KKVDLTFEWDETQLIIESFVKTKGDTGVEMEALTAASVAALTVYDMTKAVDKGIVIGPTYLLEKQGGKSGDYVR

Sequences:

>Translated_154_residues
MELTHMNDQGRARMVDVSDKPETTRTARARTSVELSSELKQLITDGDLAKGDVLAVAQVAGIMAAKETSRIIPMCHPLAL
KKVDLTFEWDETQLIIESFVKTKGDTGVEMEALTAASVAALTVYDMTKAVDKGIVIGPTYLLEKQGGKSGDYVR
>Mature_154_residues
MELTHMNDQGRARMVDVSDKPETTRTARARTSVELSSELKQLITDGDLAKGDVLAVAQVAGIMAAKETSRIIPMCHPLAL
KKVDLTFEWDETQLIIESFVKTKGDTGVEMEALTAASVAALTVYDMTKAVDKGIVIGPTYLLEKQGGKSGDYVR

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=153, Percent_Identity=56.8627450980392, Blast_Score=166, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=45.6375838926174, Blast_Score=137, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28574490, Length=155, Percent_Identity=54.8387096774194, Blast_Score=156, Evalue=4e-39,
Organism=Drosophila melanogaster, GI28574492, Length=143, Percent_Identity=55.2447552447552, Blast_Score=144, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 16715; Mature: 16715

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELTHMNDQGRARMVDVSDKPETTRTARARTSVELSSELKQLITDGDLAKGDVLAVAQVA
CCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
GIMAAKETSRIIPMCHPLALKKVDLTFEWDETQLIIESFVKTKGDTGVEMEALTAASVAA
HHHHHHCCCCCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LTVYDMTKAVDKGIVIGPTYLLEKQGGKSGDYVR
HHHHHHHHHHHCCEEECCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MELTHMNDQGRARMVDVSDKPETTRTARARTSVELSSELKQLITDGDLAKGDVLAVAQVA
CCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
GIMAAKETSRIIPMCHPLALKKVDLTFEWDETQLIIESFVKTKGDTGVEMEALTAASVAA
HHHHHHCCCCCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LTVYDMTKAVDKGIVIGPTYLLEKQGGKSGDYVR
HHHHHHHHHHHCCEEECCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA