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The map label for this gene is hchA [H]

Identifier: 229917584

GI number: 229917584

Start: 1827378

End: 1828037

Strand: Direct

Name: hchA [H]

Synonym: EAT1b_1859

Alternate gene names: 229917584

Gene position: 1827378-1828037 (Clockwise)

Preceding gene: 229917581

Following gene: 229917585

Centisome position: 60.91

GC content: 46.82

Gene sequence:

>660_bases
ATGTCGAAACATGTACTGATTGTCACGACGTCAGCAAATCAATTATCAAATGGTCATGCAACGGGACTTTGGCTTGAAGA
GTTTGCCGTTCCTTATTTATTGTTCGAAAAAGAAGGATATAAAGTGACGGTCGCGAGTATCGAAGGTGGAGACGTGCCAA
TCGATGCGAATAGTTTAGAAGATGGTTTGTCAGAAGACATTCTCAATACACGGGAATTGCTCAAAGACACAGCTCGTCTC
GATCAAGTAGCAGACGAGTCGTACGATGCAATCTTCTTACCGGGTGGTCACGGGACAGTCGTTGATTTCCCAGAAAATGA
AACGTTACAACGTGTCATTCGCAATGTATACGAGAGTGGAAATATTGTCGGGGCAGTTTGCCACGGACCAATTGGATTGG
TCAATGTGAAACTCAGCAACGATGAGCCACTCGTTAAAGATAAACAGGTGACAGGGTTCACCGATGCAGAAGAAAAAGAG
ATGCAGCTCGATTCTGCCGTCCCGTTCCTACTTGAAACAGGACTACGCAATCAAGGCGGGCAGTTCAAAGGAGCTGACAA
CTGGGCGGTGAACGTGGCGGTTGACGAACGTCTCGTCACGGGTCAGAACCCTCAGTCTTCTGAAGCGGTCGGGAAAGAAC
TTGTTAAGTTACTCGGATAA

Upstream 100 bases:

>100_bases
AGATATGCCTTGTCGTGAGACGGCAGGTCATTGGGTTTAACAGATGATGAATCGGGAACAGTAGAGTCGTATGTTGATTT
TATTGAAGGAGGAATTGAGT

Downstream 100 bases:

>100_bases
TCGTGTGAAGCAACTTCGAATGTTGAAGTTGCTTTTTTATTTTTTGGACATATGTCCTATTCAAGTCATCTCTCTTTTCG
TAAAGTCAGACGAAGAGAAA

Product: ThiJ/PfpI domain protein

Products: NA

Alternate protein names: Hsp31 [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSKHVLIVTTSANQLSNGHATGLWLEEFAVPYLLFEKEGYKVTVASIEGGDVPIDANSLEDGLSEDILNTRELLKDTARL
DQVADESYDAIFLPGGHGTVVDFPENETLQRVIRNVYESGNIVGAVCHGPIGLVNVKLSNDEPLVKDKQVTGFTDAEEKE
MQLDSAVPFLLETGLRNQGGQFKGADNWAVNVAVDERLVTGQNPQSSEAVGKELVKLLG

Sequences:

>Translated_219_residues
MSKHVLIVTTSANQLSNGHATGLWLEEFAVPYLLFEKEGYKVTVASIEGGDVPIDANSLEDGLSEDILNTRELLKDTARL
DQVADESYDAIFLPGGHGTVVDFPENETLQRVIRNVYESGNIVGAVCHGPIGLVNVKLSNDEPLVKDKQVTGFTDAEEKE
MQLDSAVPFLLETGLRNQGGQFKGADNWAVNVAVDERLVTGQNPQSSEAVGKELVKLLG
>Mature_218_residues
SKHVLIVTTSANQLSNGHATGLWLEEFAVPYLLFEKEGYKVTVASIEGGDVPIDANSLEDGLSEDILNTRELLKDTARLD
QVADESYDAIFLPGGHGTVVDFPENETLQRVIRNVYESGNIVGAVCHGPIGLVNVKLSNDEPLVKDKQVTGFTDAEEKEM
QLDSAVPFLLETGLRNQGGQFKGADNWAVNVAVDERLVTGQNPQSSEAVGKELVKLLG

Specific function: Uses temperature-induced exposure of structured hydrophobic domains to capture and stabilize early unfolding protein intermediates under severe thermal stress. It rapidly releases them once stress has abated [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family. HchA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788278, Length=195, Percent_Identity=24.1025641025641, Blast_Score=63, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320742, Length=239, Percent_Identity=31.3807531380753, Blast_Score=95, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6323984, Length=224, Percent_Identity=28.125, Blast_Score=79, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324967, Length=224, Percent_Identity=28.125, Blast_Score=78, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6324975, Length=224, Percent_Identity=28.125, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017283
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 23693; Mature: 23562

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKHVLIVTTSANQLSNGHATGLWLEEFAVPYLLFEKEGYKVTVASIEGGDVPIDANSLE
CCCEEEEEEECCCCCCCCCCCEEEHHHHCCCEEEEECCCCEEEEEEECCCCCCCCCCHHH
DGLSEDILNTRELLKDTARLDQVADESYDAIFLPGGHGTVVDFPENETLQRVIRNVYESG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHCC
NIVGAVCHGPIGLVNVKLSNDEPLVKDKQVTGFTDAEEKEMQLDSAVPFLLETGLRNQGG
CEEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCCCCC
QFKGADNWAVNVAVDERLVTGQNPQSSEAVGKELVKLLG
CCCCCCCEEEEEEECCEEECCCCCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
SKHVLIVTTSANQLSNGHATGLWLEEFAVPYLLFEKEGYKVTVASIEGGDVPIDANSLE
CCEEEEEEECCCCCCCCCCCEEEHHHHCCCEEEEECCCCEEEEEEECCCCCCCCCCHHH
DGLSEDILNTRELLKDTARLDQVADESYDAIFLPGGHGTVVDFPENETLQRVIRNVYESG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHCC
NIVGAVCHGPIGLVNVKLSNDEPLVKDKQVTGFTDAEEKEMQLDSAVPFLLETGLRNQGG
CEEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCCCCC
QFKGADNWAVNVAVDERLVTGQNPQSSEAVGKELVKLLG
CCCCCCCEEEEEEECCEEECCCCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA