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The map label for this gene is tadA [H]

Identifier: 229917437

GI number: 229917437

Start: 1671168

End: 1671668

Strand: Reverse

Name: tadA [H]

Synonym: EAT1b_1712

Alternate gene names: 229917437

Gene position: 1671668-1671168 (Counterclockwise)

Preceding gene: 229917440

Following gene: 229917436

Centisome position: 55.72

GC content: 50.7

Gene sequence:

>501_bases
ATGGAACGTGATGAGCGATTTATGCAATTGGCCATCGAAGAGGCAAAGAAAGCAGAAGCCATTGGCGAGGTGCCGATTGG
TTGTGTGATCGTGAAGGGAGACCAGGTGATCGCAACCGGGCACAATCGTCGTGAGACGGATCGATTGGCGGCAGCACACG
CCGAGATGATTGCGATTGAAACGGCCAATGAGACACTAGGGAATTGGCGATTAGAAGACTGCGAACTATACGTTACCCTT
GAACCGTGTCCGATGTGTGCGGGCGCAATCGTGTTGTCTCGCGTGAAACGTGTCATTTTCGGTGCCCACGACCCGAAAGG
TGGATGTTGTGGGACGTTGATGAACTTGGTGCAGGATGAGCGGTTCAATCACCAAGCCGAAGTGACAGAAAATGTTTTAG
CAGAAGAATGTGGACAGCTCCTGACAGATTTCTTCCGAGCGCTTCGAGAAAGGAAGAAACAAGAACGACTCAATCAGAGA
GGTTGCAACCCAATCGATTAA

Upstream 100 bases:

>100_bases
CAAAGTGCAAGTTCCATTCTAGCACACAATACGAGCGATATGGCGAGGGATTTGATTTTCATTTTTTTTCATAGTTTTAA
ACAAGAAATGAGGTGAATCG

Downstream 100 bases:

>100_bases
ACAGTATAATGTAATAGCACTCGAGATAGTGCCTAATTTCATTTACCCATTTGCCGTGCTAGGTGGGGAGGTAGCGGTGC
CCTGTCACTCGCAATCCGCT

Product: CMP/dCMP deaminase zinc-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MERDERFMQLAIEEAKKAEAIGEVPIGCVIVKGDQVIATGHNRRETDRLAAAHAEMIAIETANETLGNWRLEDCELYVTL
EPCPMCAGAIVLSRVKRVIFGAHDPKGGCCGTLMNLVQDERFNHQAEVTENVLAEECGQLLTDFFRALRERKKQERLNQR
GCNPID

Sequences:

>Translated_166_residues
MERDERFMQLAIEEAKKAEAIGEVPIGCVIVKGDQVIATGHNRRETDRLAAAHAEMIAIETANETLGNWRLEDCELYVTL
EPCPMCAGAIVLSRVKRVIFGAHDPKGGCCGTLMNLVQDERFNHQAEVTENVLAEECGQLLTDFFRALRERKKQERLNQR
GCNPID
>Mature_166_residues
MERDERFMQLAIEEAKKAEAIGEVPIGCVIVKGDQVIATGHNRRETDRLAAAHAEMIAIETANETLGNWRLEDCELYVTL
EPCPMCAGAIVLSRVKRVIFGAHDPKGGCCGTLMNLVQDERFNHQAEVTENVLAEECGQLLTDFFRALRERKKQERLNQR
GCNPID

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=173, Percent_Identity=28.9017341040462, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI145693172, Length=159, Percent_Identity=44.0251572327044, Blast_Score=141, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=46.3917525773196, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17541138, Length=148, Percent_Identity=29.0540540540541, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322425, Length=177, Percent_Identity=29.9435028248588, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6325319, Length=100, Percent_Identity=38, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=36.986301369863, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 18611; Mature: 18611

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERDERFMQLAIEEAKKAEAIGEVPIGCVIVKGDQVIATGHNRRETDRLAAAHAEMIAIE
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCCHHHHHHHHHHHHHHEEE
TANETLGNWRLEDCELYVTLEPCPMCAGAIVLSRVKRVIFGAHDPKGGCCGTLMNLVQDE
CCCHHHCCCEEECEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RFNHQAEVTENVLAEECGQLLTDFFRALRERKKQERLNQRGCNPID
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MERDERFMQLAIEEAKKAEAIGEVPIGCVIVKGDQVIATGHNRRETDRLAAAHAEMIAIE
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCCHHHHHHHHHHHHHHEEE
TANETLGNWRLEDCELYVTLEPCPMCAGAIVLSRVKRVIFGAHDPKGGCCGTLMNLVQDE
CCCHHHCCCEEECEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RFNHQAEVTENVLAEECGQLLTDFFRALRERKKQERLNQRGCNPID
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]