Click here to switch to the map view.

The map label for this gene is des [H]

Identifier: 229917131

GI number: 229917131

Start: 1376980

End: 1377993

Strand: Reverse

Name: des [H]

Synonym: EAT1b_1405

Alternate gene names: 229917131

Gene position: 1377993-1376980 (Counterclockwise)

Preceding gene: 229917132

Following gene: 229917128

Centisome position: 45.93

GC content: 47.04

Gene sequence:

>1014_bases
ATGAGTAAAGAAAAGATTGCCCAATTAAGAAAGCACGTCTCGCCGTTTGAAAAGTCCGATATTCGGATCAGTGTACGGCA
GATGATCAATACGATTTTACCGTTTCTCGTATCGTGGTTTTTAGCGTACCAACTACTGAGTGTCTCGATTTTCCTGACAT
TGCCGTTCACGTTGATTGCAGCAGGATTTGTCGTGCGGATGTTCATCATCTTCCATGACTGCACACACGGTTCATTCTTT
AAAAATAAGAAGGCGAACGCGATTGTCGGAACCATTACAGGGGTCTTGACGTTATTTCCATACGAGAAGTGGAAACGAGA
GCATGCGATTCATCATGCATCGAGTGGGAATTTGGATAAACGGGGTGTCGGCGACATCTGGGTCATGACGATTGAGGAGT
ACATAGAAGCGTCAAAATGGACTCGTCTAAAGTATCGCCTGTATCGTCATCCGCTCGTCATGTTCGGTCTCGGACCGCTC
TGGCTCATTCTCGTCACGAGTCGTTTCAATCGAAAGGACGCCCGGAAAAAAGAGCGACACAACACGTATCTCATCAATAT
CTCTCTCGTCGTCCTATATAGCGCGCTCATCTATCTGATTGGTTGGCAAGCGTTCTTGATCGTTCAAGGCACGACGATGT
TCATCGCCGGTGTGCTTGGAATCTGGTTGTTCTATGTCCAGCATACGTTTGAAGATTCATACTTCGAGGATGAGCAGGAG
TGGGATTATGTGAAGGCGGCCATTGAAGGAAGCTCGTATTATGAGTTGCCGAAAGTGCTTCAATGGGTGACGGGGAATAT
CGGATTCCACCACGTGCACCATTTGAGTCCACGCGTGCCGAACTATCATCTAGAGAAAGCACATACGTCGACACCGCCGT
TACAACGGGCAACGACAATCGGACTATTTTCAAGTTTGAAATCGTTACGTTACAAATTGTATGATGCGAACAACAAAACA
TTCGTCACGTTCCGAGAAGTGCGCCATCTCTTGCGCCGAACGAACGCAGCTTAA

Upstream 100 bases:

>100_bases
AGGGAATGCTTCCGATCCATGAATTCACATTGAACAACGTTGGTTGTTGGTTTTATCTATATTTTTGCGTTGTGACGCTG
TTGAATTCAAGGAGGTTGTT

Downstream 100 bases:

>100_bases
AAAAAGATTGTCCCTGGTCAAAAGGGACAATCTTTTTAGCGTTTCCAGACCCATTCATCACTCTCATACTTCTTGACGAG
CAAATCGATTTCAGCTTGCT

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSKEKIAQLRKHVSPFEKSDIRISVRQMINTILPFLVSWFLAYQLLSVSIFLTLPFTLIAAGFVVRMFIIFHDCTHGSFF
KNKKANAIVGTITGVLTLFPYEKWKREHAIHHASSGNLDKRGVGDIWVMTIEEYIEASKWTRLKYRLYRHPLVMFGLGPL
WLILVTSRFNRKDARKKERHNTYLINISLVVLYSALIYLIGWQAFLIVQGTTMFIAGVLGIWLFYVQHTFEDSYFEDEQE
WDYVKAAIEGSSYYELPKVLQWVTGNIGFHHVHHLSPRVPNYHLEKAHTSTPPLQRATTIGLFSSLKSLRYKLYDANNKT
FVTFREVRHLLRRTNAA

Sequences:

>Translated_337_residues
MSKEKIAQLRKHVSPFEKSDIRISVRQMINTILPFLVSWFLAYQLLSVSIFLTLPFTLIAAGFVVRMFIIFHDCTHGSFF
KNKKANAIVGTITGVLTLFPYEKWKREHAIHHASSGNLDKRGVGDIWVMTIEEYIEASKWTRLKYRLYRHPLVMFGLGPL
WLILVTSRFNRKDARKKERHNTYLINISLVVLYSALIYLIGWQAFLIVQGTTMFIAGVLGIWLFYVQHTFEDSYFEDEQE
WDYVKAAIEGSSYYELPKVLQWVTGNIGFHHVHHLSPRVPNYHLEKAHTSTPPLQRATTIGLFSSLKSLRYKLYDANNKT
FVTFREVRHLLRRTNAA
>Mature_336_residues
SKEKIAQLRKHVSPFEKSDIRISVRQMINTILPFLVSWFLAYQLLSVSIFLTLPFTLIAAGFVVRMFIIFHDCTHGSFFK
NKKANAIVGTITGVLTLFPYEKWKREHAIHHASSGNLDKRGVGDIWVMTIEEYIEASKWTRLKYRLYRHPLVMFGLGPLW
LILVTSRFNRKDARKKERHNTYLINISLVVLYSALIYLIGWQAFLIVQGTTMFIAGVLGIWLFYVQHTFEDSYFEDEQEW
DYVKAAIEGSSYYELPKVLQWVTGNIGFHHVHHLSPRVPNYHLEKAHTSTPPLQRATTIGLFSSLKSLRYKLYDANNKTF
VTFREVRHLLRRTNAA

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71999459, Length=289, Percent_Identity=23.1833910034602, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 39288; Mature: 39157

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEKIAQLRKHVSPFEKSDIRISVRQMINTILPFLVSWFLAYQLLSVSIFLTLPFTLIA
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGFVVRMFIIFHDCTHGSFFKNKKANAIVGTITGVLTLFPYEKWKREHAIHHASSGNLDK
HHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC
RGVGDIWVMTIEEYIEASKWTRLKYRLYRHPLVMFGLGPLWLILVTSRFNRKDARKKERH
CCCCCHHEEEHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHCCHHHHHHHHHC
NTYLINISLVVLYSALIYLIGWQAFLIVQGTTMFIAGVLGIWLFYVQHTFEDSYFEDEQE
CEEEEEHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
WDYVKAAIEGSSYYELPKVLQWVTGNIGFHHVHHLSPRVPNYHLEKAHTSTPPLQRATTI
HHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
GLFSSLKSLRYKLYDANNKTFVTFREVRHLLRRTNAA
HHHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKEKIAQLRKHVSPFEKSDIRISVRQMINTILPFLVSWFLAYQLLSVSIFLTLPFTLIA
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGFVVRMFIIFHDCTHGSFFKNKKANAIVGTITGVLTLFPYEKWKREHAIHHASSGNLDK
HHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC
RGVGDIWVMTIEEYIEASKWTRLKYRLYRHPLVMFGLGPLWLILVTSRFNRKDARKKERH
CCCCCHHEEEHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHCCHHHHHHHHHC
NTYLINISLVVLYSALIYLIGWQAFLIVQGTTMFIAGVLGIWLFYVQHTFEDSYFEDEQE
CEEEEEHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
WDYVKAAIEGSSYYELPKVLQWVTGNIGFHHVHHLSPRVPNYHLEKAHTSTPPLQRATTI
HHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
GLFSSLKSLRYKLYDANNKTFVTFREVRHLLRRTNAA
HHHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]