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The map label for this gene is fba [H]

Identifier: 229917075

GI number: 229917075

Start: 1318597

End: 1319451

Strand: Reverse

Name: fba [H]

Synonym: EAT1b_1349

Alternate gene names: 229917075

Gene position: 1319451-1318597 (Counterclockwise)

Preceding gene: 229917076

Following gene: 229917074

Centisome position: 43.98

GC content: 48.19

Gene sequence:

>855_bases
ATGCCATTAGTATCAATGACAGAAATGCTTAACAAAGCATTCGAAGGCAAGTATGCAGTCGGCCAATTCAACATCAACAA
CCTCGAGTGGACGCAAGCGATTCTTCGCGCTGCGGAAGACGAGAAATCACCAGTAATCCTCGGTGTATCAGAAGGTGCAG
CGAAGTACATGGGTGGCTTCACGACAGTTGTCAAAATGGTTGAAGGTCTTATGCACGACTACAACATCACTGTTCCAGTT
GCAATCCACCTTGACCACGGTTCTTCATTCGATAAGTGTAAAGCAGCGATCGACGCTGGTTTCACGTCAGTCATGATCGA
CGGTTCACACCACCCGATCGATGAAAACATCGAAATGACGAAACAAGTTGTCGAGTACGCGCACGCTAAGGGTGCTTCTG
TTGAGGCAGAAGTCGGTACAGTTGGCGGCGAAGAAGACGGCGTTATCGGTGGCGTACAATACGCTGACCTCGATGAGTGT
GTACGTGTTGTCAAAGAAGCGAAAGTGGATGCACTTGCTGCAGCACTCGGTTCTGTACACGGTGAATACCAAGGCGAGCC
GAAACTTGGCTTCAAAGAGATGGAAGAAATCGCAAACGCGACACAAACTCCACTCGTTCTTCACGGCGGATCAGGTATTC
CTGAGCACCAAATCAAAAAAGCAATCGAGCTCGGCCACAGCAAGATCAACGTTAACACAGAGTGCCAACAAGAATGGACT
CGTGCGGTACGTGAGAAAGTTGCTGCTGATGCAAAAGTATATGACCCACGTAAAATTATCGGACCTGGTATCGAAGCGAT
TTATAACGTCGTTACTGGCAAGATGCGTGAGTTTGGTTCAAGCAACCAAGCATAA

Upstream 100 bases:

>100_bases
GCATAGGCACATGTTTTACGGTGTGTTATAATGGGAACGAATTGCACGGGGGAACTTTTCCCAAACGTGTATAATAGCGA
ACAGACAGGAGGATGTCATT

Downstream 100 bases:

>100_bases
TCCTGTTTGATCAAGTCGGTTCTCTATGAGGACCGACTTTTTGTATCGTTTCCTATATCACCGTTTGTCGAATCTGACAA
AGGGAGTAGTAATTCGACTA

Product: fructose-1,6-bisphosphate aldolase, class II

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MPLVSMTEMLNKAFEGKYAVGQFNINNLEWTQAILRAAEDEKSPVILGVSEGAAKYMGGFTTVVKMVEGLMHDYNITVPV
AIHLDHGSSFDKCKAAIDAGFTSVMIDGSHHPIDENIEMTKQVVEYAHAKGASVEAEVGTVGGEEDGVIGGVQYADLDEC
VRVVKEAKVDALAAALGSVHGEYQGEPKLGFKEMEEIANATQTPLVLHGGSGIPEHQIKKAIELGHSKINVNTECQQEWT
RAVREKVAADAKVYDPRKIIGPGIEAIYNVVTGKMREFGSSNQA

Sequences:

>Translated_284_residues
MPLVSMTEMLNKAFEGKYAVGQFNINNLEWTQAILRAAEDEKSPVILGVSEGAAKYMGGFTTVVKMVEGLMHDYNITVPV
AIHLDHGSSFDKCKAAIDAGFTSVMIDGSHHPIDENIEMTKQVVEYAHAKGASVEAEVGTVGGEEDGVIGGVQYADLDEC
VRVVKEAKVDALAAALGSVHGEYQGEPKLGFKEMEEIANATQTPLVLHGGSGIPEHQIKKAIELGHSKINVNTECQQEWT
RAVREKVAADAKVYDPRKIIGPGIEAIYNVVTGKMREFGSSNQA
>Mature_283_residues
PLVSMTEMLNKAFEGKYAVGQFNINNLEWTQAILRAAEDEKSPVILGVSEGAAKYMGGFTTVVKMVEGLMHDYNITVPVA
IHLDHGSSFDKCKAAIDAGFTSVMIDGSHHPIDENIEMTKQVVEYAHAKGASVEAEVGTVGGEEDGVIGGVQYADLDECV
RVVKEAKVDALAAALGSVHGEYQGEPKLGFKEMEEIANATQTPLVLHGGSGIPEHQIKKAIELGHSKINVNTECQQEWTR
AVREKVAADAKVYDPRKIIGPGIEAIYNVVTGKMREFGSSNQA

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=286, Percent_Identity=38.1118881118881, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI87082041, Length=287, Percent_Identity=35.5400696864112, Blast_Score=180, Evalue=9e-47,
Organism=Escherichia coli, GI1788072, Length=240, Percent_Identity=38.75, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789293, Length=308, Percent_Identity=26.9480519480519, Blast_Score=85, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322790, Length=338, Percent_Identity=26.0355029585799, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 30584; Mature: 30453

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVSMTEMLNKAFEGKYAVGQFNINNLEWTQAILRAAEDEKSPVILGVSEGAAKYMGGF
CCCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHH
TTVVKMVEGLMHDYNITVPVAIHLDHGSSFDKCKAAIDAGFTSVMIDGSHHPIDENIEMT
HHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHH
KQVVEYAHAKGASVEAEVGTVGGEEDGVIGGVQYADLDECVRVVKEAKVDALAAALGSVH
HHHHHHHHCCCCCCEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GEYQGEPKLGFKEMEEIANATQTPLVLHGGSGIPEHQIKKAIELGHSKINVNTECQQEWT
CCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHCCCEECCCCHHHHHHH
RAVREKVAADAKVYDPRKIIGPGIEAIYNVVTGKMREFGSSNQA
HHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PLVSMTEMLNKAFEGKYAVGQFNINNLEWTQAILRAAEDEKSPVILGVSEGAAKYMGGF
CCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHH
TTVVKMVEGLMHDYNITVPVAIHLDHGSSFDKCKAAIDAGFTSVMIDGSHHPIDENIEMT
HHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHH
KQVVEYAHAKGASVEAEVGTVGGEEDGVIGGVQYADLDECVRVVKEAKVDALAAALGSVH
HHHHHHHHCCCCCCEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GEYQGEPKLGFKEMEEIANATQTPLVLHGGSGIPEHQIKKAIELGHSKINVNTECQQEWT
CCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHCCCEECCCCHHHHHHH
RAVREKVAADAKVYDPRKIIGPGIEAIYNVVTGKMREFGSSNQA
HHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA