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The map label for this gene is ywlC [H]

Identifier: 229917062

GI number: 229917062

Start: 1305927

End: 1306937

Strand: Reverse

Name: ywlC [H]

Synonym: EAT1b_1336

Alternate gene names: 229917062

Gene position: 1306937-1305927 (Counterclockwise)

Preceding gene: 229917063

Following gene: 229917061

Centisome position: 43.57

GC content: 53.12

Gene sequence:

>1011_bases
ATGGAAACGAAATGGATTAATTCGAATGAGATTGAAGAGGGGGTACGTCTTCTTCAAGCGGGTGAAATCATCGCCATGCC
GACAGAAACCGTCTATGGTCTCGCGGGAGATGCCATGAACGATGTGGCAATTCGAAAGATTTTTGAGGCAAAAGGTCGTC
CGTCGGATAACCCGCTCATCGTCCATATCGCTTCAATCGAACAAACGAGTTTGTTTGTCGATTCGATTCCTCCTGTTGCC
AAACGCTTGATGGATGCGTTTTGGCCAGGCGCTTTGACGATCATCTTGCCTTCAAACGGCCGAGCCTCTTCGCTCGTGAC
CGCGGGCCTCGATTCCATCGGGCTCCGGATGCCGAACCATCCGGCAGCACTCGAATTAATTCGTAAGTCGGGATTAGGAC
TTGCGGCTCCGAGTGCGAATCGTTCGGGACGTCCTTCACCGACGACCGCTCAACACGTCGCGGATGATTTGAACGGACGA
ATCGCAGGAATCGTGGATGGAGGTCCTACCGGAATCGGAGTCGAGTCAACCGTTGTGGATTGTACGGGTGACACGGTAAC
GATTTTACGACCAGGTGGTGTGACGCGAGAAGAAATGGAAGCCGTCATTGGCCCAGTCGCCTTAGATGCCAATTTGAGCA
ACGATGAAGCCGCGCCACGATCGCCGGGAATGAAATATACGCACTATGCCCCGACAGCACCTGTTTTTTTAGTCGATGGG
ACACGTGAAGATTTGGAGCGTGTCATCGAGGAGCGGAAGCAAGCGGGGTTACGAATCGGTGCCCTCGTCTTCGACGAGAA
CCCGACACCGGCTGAGGTCACGTATTCACTCGGGACCTCGATGGAAGTGGCGGCGCAACGCTTATACGATGCGCTTCGTC
GATTTGATGAAACAGACGTGGATGAGATTTATGTGAACACGATTGAACCGGTCGGAGTTGCATTAGCCGTCTATAACCGT
TTATACAAAGCGGCGGGCGGAAAGGTTGTGCACCCGACGAAAGATGCCTAA

Upstream 100 bases:

>100_bases
TCATTACTGTCTGAACGTTATCCTGAAGCAGAAACGGGTATTTTAAAAGATATAAACGGCAAGGACCGTATCGTCTATGC
CGTAAGGGAAGGGATTGCGT

Downstream 100 bases:

>100_bases
AGACATAGAGGAGGACACGCGATGTCAATGAAACGCGTATTATTCATATGTAGTGGCAACACGTGCCGAAGCCCGATGGC
GATGGCCTTGCTCCGTTCGA

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
METKWINSNEIEEGVRLLQAGEIIAMPTETVYGLAGDAMNDVAIRKIFEAKGRPSDNPLIVHIASIEQTSLFVDSIPPVA
KRLMDAFWPGALTIILPSNGRASSLVTAGLDSIGLRMPNHPAALELIRKSGLGLAAPSANRSGRPSPTTAQHVADDLNGR
IAGIVDGGPTGIGVESTVVDCTGDTVTILRPGGVTREEMEAVIGPVALDANLSNDEAAPRSPGMKYTHYAPTAPVFLVDG
TREDLERVIEERKQAGLRIGALVFDENPTPAEVTYSLGTSMEVAAQRLYDALRRFDETDVDEIYVNTIEPVGVALAVYNR
LYKAAGGKVVHPTKDA

Sequences:

>Translated_336_residues
METKWINSNEIEEGVRLLQAGEIIAMPTETVYGLAGDAMNDVAIRKIFEAKGRPSDNPLIVHIASIEQTSLFVDSIPPVA
KRLMDAFWPGALTIILPSNGRASSLVTAGLDSIGLRMPNHPAALELIRKSGLGLAAPSANRSGRPSPTTAQHVADDLNGR
IAGIVDGGPTGIGVESTVVDCTGDTVTILRPGGVTREEMEAVIGPVALDANLSNDEAAPRSPGMKYTHYAPTAPVFLVDG
TREDLERVIEERKQAGLRIGALVFDENPTPAEVTYSLGTSMEVAAQRLYDALRRFDETDVDEIYVNTIEPVGVALAVYNR
LYKAAGGKVVHPTKDA
>Mature_336_residues
METKWINSNEIEEGVRLLQAGEIIAMPTETVYGLAGDAMNDVAIRKIFEAKGRPSDNPLIVHIASIEQTSLFVDSIPPVA
KRLMDAFWPGALTIILPSNGRASSLVTAGLDSIGLRMPNHPAALELIRKSGLGLAAPSANRSGRPSPTTAQHVADDLNGR
IAGIVDGGPTGIGVESTVVDCTGDTVTILRPGGVTREEMEAVIGPVALDANLSNDEAAPRSPGMKYTHYAPTAPVFLVDG
TREDLERVIEERKQAGLRIGALVFDENPTPAEVTYSLGTSMEVAAQRLYDALRRFDETDVDEIYVNTIEPVGVALAVYNR
LYKAAGGKVVHPTKDA

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=150, Percent_Identity=30, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17537239, Length=195, Percent_Identity=28.2051282051282, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6321269, Length=374, Percent_Identity=40.1069518716578, Blast_Score=219, Evalue=4e-58,
Organism=Drosophila melanogaster, GI78707274, Length=171, Percent_Identity=31.5789473684211, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 35804; Mature: 35804

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKWINSNEIEEGVRLLQAGEIIAMPTETVYGLAGDAMNDVAIRKIFEAKGRPSDNPLI
CCCCCCCCHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEE
VHIASIEQTSLFVDSIPPVAKRLMDAFWPGALTIILPSNGRASSLVTAGLDSIGLRMPNH
EEEECCCCHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHCHHHHCCCCCCC
PAALELIRKSGLGLAAPSANRSGRPSPTTAQHVADDLNGRIAGIVDGGPTGIGVESTVVD
HHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEE
CTGDTVTILRPGGVTREEMEAVIGPVALDANLSNDEAAPRSPGMKYTHYAPTAPVFLVDG
CCCCEEEEECCCCCCHHHHHHHHCCEEEECCCCCCCCCCCCCCCEEEEECCCCCEEEECC
TREDLERVIEERKQAGLRIGALVFDENPTPAEVTYSLGTSMEVAAQRLYDALRRFDETDV
CHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCH
DEIYVNTIEPVGVALAVYNRLYKAAGGKVVHPTKDA
HHEEEECCCHHHHHHHHHHHHHHHCCCEEECCCCCC
>Mature Secondary Structure
METKWINSNEIEEGVRLLQAGEIIAMPTETVYGLAGDAMNDVAIRKIFEAKGRPSDNPLI
CCCCCCCCHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEE
VHIASIEQTSLFVDSIPPVAKRLMDAFWPGALTIILPSNGRASSLVTAGLDSIGLRMPNH
EEEECCCCHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHCHHHHCCCCCCC
PAALELIRKSGLGLAAPSANRSGRPSPTTAQHVADDLNGRIAGIVDGGPTGIGVESTVVD
HHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEE
CTGDTVTILRPGGVTREEMEAVIGPVALDANLSNDEAAPRSPGMKYTHYAPTAPVFLVDG
CCCCEEEEECCCCCCHHHHHHHHCCEEEECCCCCCCCCCCCCCCEEEEECCCCCEEEECC
TREDLERVIEERKQAGLRIGALVFDENPTPAEVTYSLGTSMEVAAQRLYDALRRFDETDV
CHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCH
DEIYVNTIEPVGVALAVYNRLYKAAGGKVVHPTKDA
HHEEEECCCHHHHHHHHHHHHHHHCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]