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The map label for this gene is yhcK [H]

Identifier: 229917001

GI number: 229917001

Start: 1252071

End: 1253156

Strand: Direct

Name: yhcK [H]

Synonym: EAT1b_1275

Alternate gene names: 229917001

Gene position: 1252071-1253156 (Clockwise)

Preceding gene: 229917000

Following gene: 229917009

Centisome position: 41.74

GC content: 47.42

Gene sequence:

>1086_bases
ATGACGCTCACCGTTTTGTTGCTCAATGCTTGTGTCGCATTCACCGGGTTTTATATCATCTCAAAGATTTATCATTCTTC
GCTTTTTAATTCGTACCGCCTTCGTAGTTTCATGATTGGGCTACTCGCAGGTGCACTCGGGCTGTTTTTGATGTATAACG
CCGTGGAAGTCAACGATACGGTCCGTGTCGATTTACGTCACTTACCCCTCGTGTTGCTTGCTTTTTATGGTGCTCGTTTT
CCTTTATTCATCGCAACACTCTTCATCGCCAATACACGATTCTTGTTCGGAATGACCGAACAAGCGGCGATTGCGTTTGT
CGCGACCTTCCTCGTCAGTATCGGGATGCTCTGGATTCATCGGTTGTTTCGGGAGCGACTTTTCATCCAAAGCCTCTTTT
TGAACGTGTGGGCGCTCTTCATTATTTCGATTGCCGTCTATATCAATATGGGTTGGAGCACGGCTTATGTATCCCTCGTC
TTGACCATTTGGATGATTGGAATGCTTGTTGGATTGCTCTCAAGTATCCTCACCATCGACCTGGAACAAACGACTCGCCG
GGCCATCGAGTATAAGCAGTCGTCTGAACGAGATCATTTGACCGGTCTATACAATCGACGTGTATGGGATCGATATACGG
CATCCGTCGGGCAAGAGAATCGGACGTATAATGTGCTTGCGCTCGATATCGATCATTTTAAACATGTGAACGATACATAC
GGTCACGGAAACGGTGATCTCGTCTTACAACAGTTCGCCAATATCTTAAAAGTCGAGACGCGTGCCCATGATACGGTCGC
ACGAATCGGTGGGGAAGAATTTGTCATCTTGATGTACGATTTGAGTCCAGAGAAAGTCGATAAAGTGGCGAATCGGATTC
GGGAACGAATTGCCACTGAACTGTTCTATTTGAACGATTTTCCACCGATTCAAATCACGACGTCGGTCGGTGTCGCCCAT
GGGACCTCGCTTCCCATCAAACGGATGGTCGACCTTGCGGATTCAGCGCTCTATCAAGCAAAAAACGAAGGGCGCAATCA
AGTTGTCGTCTCGACCTATGGCGTACCAGAACCAATCATGACATGA

Upstream 100 bases:

>100_bases
CTGGATCTGCTTTTTTGCATATTATGAAGCATTTTGTAATTGACATTATTTTGAAGACTGCTACCGTTAATGTATAGTCT
ACCGAAAAGGTCGTGAAGGA

Downstream 100 bases:

>100_bases
ACGAACCCCGCTCCAAGTGGAAGCGGGGTTTGTTGTACTCATTTGGTAAACCGTTCAACCTCATCTGTCATGATGGCCGA
AACCGCTATCGGGGGTAAGT

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MTLTVLLLNACVAFTGFYIISKIYHSSLFNSYRLRSFMIGLLAGALGLFLMYNAVEVNDTVRVDLRHLPLVLLAFYGARF
PLFIATLFIANTRFLFGMTEQAAIAFVATFLVSIGMLWIHRLFRERLFIQSLFLNVWALFIISIAVYINMGWSTAYVSLV
LTIWMIGMLVGLLSSILTIDLEQTTRRAIEYKQSSERDHLTGLYNRRVWDRYTASVGQENRTYNVLALDIDHFKHVNDTY
GHGNGDLVLQQFANILKVETRAHDTVARIGGEEFVILMYDLSPEKVDKVANRIRERIATELFYLNDFPPIQITTSVGVAH
GTSLPIKRMVDLADSALYQAKNEGRNQVVVSTYGVPEPIMT

Sequences:

>Translated_361_residues
MTLTVLLLNACVAFTGFYIISKIYHSSLFNSYRLRSFMIGLLAGALGLFLMYNAVEVNDTVRVDLRHLPLVLLAFYGARF
PLFIATLFIANTRFLFGMTEQAAIAFVATFLVSIGMLWIHRLFRERLFIQSLFLNVWALFIISIAVYINMGWSTAYVSLV
LTIWMIGMLVGLLSSILTIDLEQTTRRAIEYKQSSERDHLTGLYNRRVWDRYTASVGQENRTYNVLALDIDHFKHVNDTY
GHGNGDLVLQQFANILKVETRAHDTVARIGGEEFVILMYDLSPEKVDKVANRIRERIATELFYLNDFPPIQITTSVGVAH
GTSLPIKRMVDLADSALYQAKNEGRNQVVVSTYGVPEPIMT
>Mature_360_residues
TLTVLLLNACVAFTGFYIISKIYHSSLFNSYRLRSFMIGLLAGALGLFLMYNAVEVNDTVRVDLRHLPLVLLAFYGARFP
LFIATLFIANTRFLFGMTEQAAIAFVATFLVSIGMLWIHRLFRERLFIQSLFLNVWALFIISIAVYINMGWSTAYVSLVL
TIWMIGMLVGLLSSILTIDLEQTTRRAIEYKQSSERDHLTGLYNRRVWDRYTASVGQENRTYNVLALDIDHFKHVNDTYG
HGNGDLVLQQFANILKVETRAHDTVARIGGEEFVILMYDLSPEKVDKVANRIRERIATELFYLNDFPPIQITTSVGVAHG
TSLPIKRMVDLADSALYQAKNEGRNQVVVSTYGVPEPIMT

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1787262, Length=167, Percent_Identity=39.5209580838323, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1786584, Length=236, Percent_Identity=30.9322033898305, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI145693134, Length=156, Percent_Identity=35.2564102564103, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081881, Length=177, Percent_Identity=35.0282485875706, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87082007, Length=161, Percent_Identity=35.4037267080745, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787802, Length=165, Percent_Identity=32.7272727272727, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788085, Length=203, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1787816, Length=158, Percent_Identity=36.7088607594937, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788381, Length=191, Percent_Identity=29.3193717277487, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787056, Length=168, Percent_Identity=29.7619047619048, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87081974, Length=125, Percent_Identity=32.8, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787541, Length=182, Percent_Identity=33.5164835164835, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788956, Length=160, Percent_Identity=31.25, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081977, Length=160, Percent_Identity=28.125, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 40988; Mature: 40857

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTVLLLNACVAFTGFYIISKIYHSSLFNSYRLRSFMIGLLAGALGLFLMYNAVEVNDT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCE
VRVDLRHLPLVLLAFYGARFPLFIATLFIANTRFLFGMTEQAAIAFVATFLVSIGMLWIH
EEEHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHHHHHHH
RLFRERLFIQSLFLNVWALFIISIAVYINMGWSTAYVSLVLTIWMIGMLVGLLSSILTID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEH
LEQTTRRAIEYKQSSERDHLTGLYNRRVWDRYTASVGQENRTYNVLALDIDHFKHVNDTY
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHCCCCCC
GHGNGDLVLQQFANILKVETRAHDTVARIGGEEFVILMYDLSPEKVDKVANRIRERIATE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
LFYLNDFPPIQITTSVGVAHGTSLPIKRMVDLADSALYQAKNEGRNQVVVSTYGVPEPIM
HHEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
T
C
>Mature Secondary Structure 
TLTVLLLNACVAFTGFYIISKIYHSSLFNSYRLRSFMIGLLAGALGLFLMYNAVEVNDT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCE
VRVDLRHLPLVLLAFYGARFPLFIATLFIANTRFLFGMTEQAAIAFVATFLVSIGMLWIH
EEEHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHHHHHHH
RLFRERLFIQSLFLNVWALFIISIAVYINMGWSTAYVSLVLTIWMIGMLVGLLSSILTID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEH
LEQTTRRAIEYKQSSERDHLTGLYNRRVWDRYTASVGQENRTYNVLALDIDHFKHVNDTY
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHCCCCCC
GHGNGDLVLQQFANILKVETRAHDTVARIGGEEFVILMYDLSPEKVDKVANRIRERIATE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
LFYLNDFPPIQITTSVGVAHGTSLPIKRMVDLADSALYQAKNEGRNQVVVSTYGVPEPIM
HHEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
T
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]