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The map label for this gene is hexR [C]

Identifier: 229916944

GI number: 229916944

Start: 1193853

End: 1194701

Strand: Reverse

Name: hexR [C]

Synonym: EAT1b_1218

Alternate gene names: 229916944

Gene position: 1194701-1193853 (Counterclockwise)

Preceding gene: 229916953

Following gene: 229916943

Centisome position: 39.82

GC content: 52.65

Gene sequence:

>849_bases
ATGGAAACGATGAACGGGACGGCCCGCATCCGTGGTGCCTATTCGACACTGAGTAAGAAAGAACAACGTATTGCCGACTA
TATTTTGAAGCAACCAGAACAAATCATTCATCATACGATCAATCAGGTGGCAGATGACCTCGATGTGGCAGAGTCTACTG
TGTTTCGTTTTTGTCAGCGTGTCGGATTCAAAGGCTATCAGGCGCTAAAAATCGCACTCGCCTCAGATGTCGTCGCACCG
CTCCAAGACATCCATGAAGATATTACCGAGACGGATACGGCGCTCGAAATCGCAGAGAAAATTTTTTCGACGAACGGAAA
GACGATTGAGTCGACGCGTCAGATCTTAGAAGGAGTCTCTTTAGAGAAAGCCGTTGAGCTGTTCCTCGGGGCGCGCCGTA
TCGAATTTTTCGGGAGCGGCGGGTCGGCCGTCGTCGCGTTAGATGCGTATCATAAGTTTGTCCGAAGCGGGCTTCAAGTG
AGCGCGATGCTCGAGTCGCATATGCAGCTGATGTCGGCCTCACAATTGACGACCGCAGACGTCGCCGTCGTCATCTCGCA
TTCCGGTGCCTCGAAAGAGACACTCGATATCGCCAAACTCTTAAAAGAGAAGGGTGTGCCGATGATTGCCATCACGAACT
ATGCGAAGTCCCCTCTCTCAAAAATCGCGGACGTGTCGCTCTATACCGTGTCCCAAGAGACAGCATTCCGTTCTGAGGCG
CTCGCTTCTCGCATCGCCGAACTGAGCCTGATTGATGCGTTGTTTACGGCTGTCATGATGCGTCGAGGCGAGGCGGCCCG
GACATCGCTTCAACAGATGCGTGAGGCGATTTCGATGCGCCGAATCTGA

Upstream 100 bases:

>100_bases
CTACTTTTGTAAGGTGGGTCAATCATTTGCATGAATCACACATTGCGGAATTTTTTTCGAAACGGTATCGTTAGATGAAG
AAGAGAAAGGGTGATTCTTG

Downstream 100 bases:

>100_bases
GCGAAATAGGGTTAGTTTCTACAAAAAGGTGGAAATTATAAACCCTGAGAGCAAAGCGAGGCTTAGAGAGAGAAGGTGGA
CCGATGAACCATATTGATTT

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
METMNGTARIRGAYSTLSKKEQRIADYILKQPEQIIHHTINQVADDLDVAESTVFRFCQRVGFKGYQALKIALASDVVAP
LQDIHEDITETDTALEIAEKIFSTNGKTIESTRQILEGVSLEKAVELFLGARRIEFFGSGGSAVVALDAYHKFVRSGLQV
SAMLESHMQLMSASQLTTADVAVVISHSGASKETLDIAKLLKEKGVPMIAITNYAKSPLSKIADVSLYTVSQETAFRSEA
LASRIAELSLIDALFTAVMMRRGEAARTSLQQMREAISMRRI

Sequences:

>Translated_282_residues
METMNGTARIRGAYSTLSKKEQRIADYILKQPEQIIHHTINQVADDLDVAESTVFRFCQRVGFKGYQALKIALASDVVAP
LQDIHEDITETDTALEIAEKIFSTNGKTIESTRQILEGVSLEKAVELFLGARRIEFFGSGGSAVVALDAYHKFVRSGLQV
SAMLESHMQLMSASQLTTADVAVVISHSGASKETLDIAKLLKEKGVPMIAITNYAKSPLSKIADVSLYTVSQETAFRSEA
LASRIAELSLIDALFTAVMMRRGEAARTSLQQMREAISMRRI
>Mature_282_residues
METMNGTARIRGAYSTLSKKEQRIADYILKQPEQIIHHTINQVADDLDVAESTVFRFCQRVGFKGYQALKIALASDVVAP
LQDIHEDITETDTALEIAEKIFSTNGKTIESTRQILEGVSLEKAVELFLGARRIEFFGSGGSAVVALDAYHKFVRSGLQV
SAMLESHMQLMSASQLTTADVAVVISHSGASKETLDIAKLLKEKGVPMIAITNYAKSPLSKIADVSLYTVSQETAFRSEA
LASRIAELSLIDALFTAVMMRRGEAARTSLQQMREAISMRRI

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=279, Percent_Identity=32.6164874551971, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI87082369, Length=256, Percent_Identity=28.90625, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1788767, Length=258, Percent_Identity=31.0077519379845, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI87082130, Length=267, Percent_Identity=31.0861423220974, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30960; Mature: 30960

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METMNGTARIRGAYSTLSKKEQRIADYILKQPEQIIHHTINQVADDLDVAESTVFRFCQR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGFKGYQALKIALASDVVAPLQDIHEDITETDTALEIAEKIFSTNGKTIESTRQILEGVS
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
LEKAVELFLGARRIEFFGSGGSAVVALDAYHKFVRSGLQVSAMLESHMQLMSASQLTTAD
HHHHHHHHHHHHHHEEECCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHH
VAVVISHSGASKETLDIAKLLKEKGVPMIAITNYAKSPLSKIADVSLYTVSQETAFRSEA
HEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHEEECHHHHHHHHH
LASRIAELSLIDALFTAVMMRRGEAARTSLQQMREAISMRRI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
METMNGTARIRGAYSTLSKKEQRIADYILKQPEQIIHHTINQVADDLDVAESTVFRFCQR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGFKGYQALKIALASDVVAPLQDIHEDITETDTALEIAEKIFSTNGKTIESTRQILEGVS
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
LEKAVELFLGARRIEFFGSGGSAVVALDAYHKFVRSGLQVSAMLESHMQLMSASQLTTAD
HHHHHHHHHHHHHHEEECCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHH
VAVVISHSGASKETLDIAKLLKEKGVPMIAITNYAKSPLSKIADVSLYTVSQETAFRSEA
HEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHEEECHHHHHHHHH
LASRIAELSLIDALFTAVMMRRGEAARTSLQQMREAISMRRI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]