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The map label for this gene is galE [H]

Identifier: 229916935

GI number: 229916935

Start: 1182681

End: 1183697

Strand: Reverse

Name: galE [H]

Synonym: EAT1b_1209

Alternate gene names: 229916935

Gene position: 1183697-1182681 (Counterclockwise)

Preceding gene: 229916936

Following gene: 229916934

Centisome position: 39.46

GC content: 51.72

Gene sequence:

>1017_bases
ATGAAAACAATTTTTGTGACAGGTGGCGCGGGGTACATCGGGACACACACGACCGTTCAATTACTTGAGGCAGGATACGA
GGTCATTATTTTGGATAACCTGTCCAACAGCCGACAAGAGGCAATCCAGCGAATCGAGATCCTGACGGGGAAAACGGTCA
CCTTATACGTGGGCGATATTCGAGATCAGGAATTGCTCGATGAAATCTTCTCGACGCACTCGATTCATGCGGTCGTTCAC
TTCGCCGGTCTAAAGGCAGTCGGCGAATCTGTCAGTCAACCACTTCACTACTATGACAACAACGTGGCCGGGACGCTCGT
CTTATTGCGGATGATGGACCAGTACGGGATCAAACGTATCGTCTTCAGTTCATCGGCGACCGTTTACGGAATCCCGACCA
CATCACCGGTCGATGAATCGTTCCCACTCAGTGCGACTAATCCGTATGGACGAACGAAGCTGATGATTGAAGAGATGTTG
CGCGACCTCTATACGGCCGATCCGTCGTGGTCGATTGCGATTCTTCGCTATTTCAATCCGATTGGCGCTCACGACTCCGG
GACGATTGGAGAAGATCCGTTCGATGTCCCGAACAACTTGATGCCATACATCACACAAGTTGCAGCCGGACGTCTGAAAG
AACTTCAAGTGTTCGGAGATGACTATCCGACGCATGACGGGACAGGCGTGCGCGACTATATCCATGTCGTGGATTTGGCG
CTTGGTCATTTAAAGGCGTTGGAGTATGTAGGGAATCACGTGGGAGTGGAGGCGTTCAATCTCGGGACCGGGAAAGGATA
CAGCGTCCTCGATTTGCTTCAAACGTTCCAACAGGAGAGCGGACAGACGATTCCTTATCAAATCACGGGTAAGCGAGACG
GAGACGTCGCGGCGATTTTTGCCGACCCGCAAAAGTCGAAGGCCATTCTCGGCTGGGAGGTACGACATGACATCGAAGCG
ATGTGTCGGGACGCCTGGCGTTGGCAATCGAATAATCCTAAAGGATACAGTGAATAA

Upstream 100 bases:

>100_bases
CTCCGCGGACGGATACGTTCCGTCGTGTCGGGGACTGGCTCAATGACCGCTCGGCTTAACAATCGCTGCAGATGGACTTT
TAGAAAATGGGGTGAAGCAC

Downstream 100 bases:

>100_bases
GCTTTATAAGTAGGCGGTCATCACACGATGGCCGTCTCTTTTTGTATTAGAAAGAGTGGTGAACGGGAACACCTAATGGA
ACATCATTTTACTTAGGAGG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKTIFVTGGAGYIGTHTTVQLLEAGYEVIILDNLSNSRQEAIQRIEILTGKTVTLYVGDIRDQELLDEIFSTHSIHAVVH
FAGLKAVGESVSQPLHYYDNNVAGTLVLLRMMDQYGIKRIVFSSSATVYGIPTTSPVDESFPLSATNPYGRTKLMIEEML
RDLYTADPSWSIAILRYFNPIGAHDSGTIGEDPFDVPNNLMPYITQVAAGRLKELQVFGDDYPTHDGTGVRDYIHVVDLA
LGHLKALEYVGNHVGVEAFNLGTGKGYSVLDLLQTFQQESGQTIPYQITGKRDGDVAAIFADPQKSKAILGWEVRHDIEA
MCRDAWRWQSNNPKGYSE

Sequences:

>Translated_338_residues
MKTIFVTGGAGYIGTHTTVQLLEAGYEVIILDNLSNSRQEAIQRIEILTGKTVTLYVGDIRDQELLDEIFSTHSIHAVVH
FAGLKAVGESVSQPLHYYDNNVAGTLVLLRMMDQYGIKRIVFSSSATVYGIPTTSPVDESFPLSATNPYGRTKLMIEEML
RDLYTADPSWSIAILRYFNPIGAHDSGTIGEDPFDVPNNLMPYITQVAAGRLKELQVFGDDYPTHDGTGVRDYIHVVDLA
LGHLKALEYVGNHVGVEAFNLGTGKGYSVLDLLQTFQQESGQTIPYQITGKRDGDVAAIFADPQKSKAILGWEVRHDIEA
MCRDAWRWQSNNPKGYSE
>Mature_338_residues
MKTIFVTGGAGYIGTHTTVQLLEAGYEVIILDNLSNSRQEAIQRIEILTGKTVTLYVGDIRDQELLDEIFSTHSIHAVVH
FAGLKAVGESVSQPLHYYDNNVAGTLVLLRMMDQYGIKRIVFSSSATVYGIPTTSPVDESFPLSATNPYGRTKLMIEEML
RDLYTADPSWSIAILRYFNPIGAHDSGTIGEDPFDVPNNLMPYITQVAAGRLKELQVFGDDYPTHDGTGVRDYIHVVDLA
LGHLKALEYVGNHVGVEAFNLGTGKGYSVLDLLQTFQQESGQTIPYQITGKRDGDVAAIFADPQKSKAILGWEVRHDIEA
MCRDAWRWQSNNPKGYSE

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=342, Percent_Identity=53.5087719298246, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI56118217, Length=342, Percent_Identity=53.5087719298246, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI189083684, Length=342, Percent_Identity=53.5087719298246, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI7657641, Length=281, Percent_Identity=27.4021352313167, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI42516563, Length=321, Percent_Identity=24.2990654205607, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=54.4642857142857, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI48994969, Length=364, Percent_Identity=23.9010989010989, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788353, Length=362, Percent_Identity=25.1381215469613, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=48.9855072463768, Blast_Score=353, Evalue=7e-98,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=48.7031700288184, Blast_Score=352, Evalue=2e-97,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=51.453488372093, Blast_Score=376, Evalue=1e-105,
Organism=Drosophila melanogaster, GI19923002, Length=344, Percent_Identity=53.1976744186046, Blast_Score=379, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37406; Mature: 37406

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIFVTGGAGYIGTHTTVQLLEAGYEVIILDNLSNSRQEAIQRIEILTGKTVTLYVGDI
CEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECC
RDQELLDEIFSTHSIHAVVHFAGLKAVGESVSQPLHYYDNNVAGTLVLLRMMDQYGIKRI
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHCCEEE
VFSSSATVYGIPTTSPVDESFPLSATNPYGRTKLMIEEMLRDLYTADPSWSIAILRYFNP
EEECCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
IGAHDSGTIGEDPFDVPNNLMPYITQVAAGRLKELQVFGDDYPTHDGTGVRDYIHVVDLA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHH
LGHLKALEYVGNHVGVEAFNLGTGKGYSVLDLLQTFQQESGQTIPYQITGKRDGDVAAIF
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEE
ADPQKSKAILGWEVRHDIEAMCRDAWRWQSNNPKGYSE
ECCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKTIFVTGGAGYIGTHTTVQLLEAGYEVIILDNLSNSRQEAIQRIEILTGKTVTLYVGDI
CEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECC
RDQELLDEIFSTHSIHAVVHFAGLKAVGESVSQPLHYYDNNVAGTLVLLRMMDQYGIKRI
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHCCEEE
VFSSSATVYGIPTTSPVDESFPLSATNPYGRTKLMIEEMLRDLYTADPSWSIAILRYFNP
EEECCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
IGAHDSGTIGEDPFDVPNNLMPYITQVAAGRLKELQVFGDDYPTHDGTGVRDYIHVVDLA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHH
LGHLKALEYVGNHVGVEAFNLGTGKGYSVLDLLQTFQQESGQTIPYQITGKRDGDVAAIF
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEE
ADPQKSKAILGWEVRHDIEAMCRDAWRWQSNNPKGYSE
ECCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]