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The map label for this gene is yqeC [H]

Identifier: 229916932

GI number: 229916932

Start: 1180414

End: 1181298

Strand: Direct

Name: yqeC [H]

Synonym: EAT1b_1206

Alternate gene names: 229916932

Gene position: 1180414-1181298 (Clockwise)

Preceding gene: 229916926

Following gene: 229916941

Centisome position: 39.35

GC content: 53.67

Gene sequence:

>885_bases
ATGGAAATCGGTATGATCGGACTTGGTAAAATGGGTCTCAATTTGGCTCTGAATTTGACAGACAATGGGCATCGTGTCGT
CGGGTATGACCCGGGAAACGTATCGACGAGTCAATTTGAGACGAAAGACTCTTTGCAGGAGGTCGTTTCCACGCTTCAGG
CCCCTCGCGTCGTCTGGGTGATGGTGCCAGCGGGTGACGTGACCGAGCACGTCTTGAACGACTTGCACCATCTTCTCTCC
CCAGGTGACATCGTCATCGATGGAGGAAACTCGAACTACAAGGAGTCAATGCGACGTTCCGAGCACTTTAAAGAAAAACT
AATCTATTTGTTCGATGTCGGGACGAGTGGTGGGATGGAAGGTGCCCGTCACGGAGCGTGTACGATGATTGGAGGCGACT
TGGAAGCGTTCGGAAAAATCGAACAGCTCTTCCAAGACGTCTCGACCGACCACGGTTATCTGTATGCGGGACCAAGTGGA
AGTGGTCACTTTTTGAAGATGGTGCATAATGGGATTGAGTATGGGATGATGCAGGCGATCGCAGAAGGGTTCGAGGTGCT
CGAGAAGAGTCCGTTCGACTATGACTATGAAGATGTCTCACGTGTGTGGAACCACGGCTCGGTCATTCGCTCTTGGCTCA
TGGAGTTGACGGAGAGTGCCTTCTCGAAAGATGCGAAGCTCAACGACATCCGTGGGGTCATGCATGCGTCCGGTGAAGGC
AAGTGGACGGTCGAGACGGCACTCGAGTACGACGTCCCGACGCCTGTCATCGCGCTCTCCCTCATGATGCGTCAACGCTC
GCTTCAAGACGATACGTTCTCGGGCAAGGTCGTCGCGGCCTTACGGAACGAGTTCGGTGGGCATGCGGTGGAGAAGAAAG
AATAG

Upstream 100 bases:

>100_bases
ACTTATATCATTCTACATCTCGGGCAACCTGTCCTTTTGAGCAATCGTTATTTCGGGTATGCCCTATAGAGGACTAAATC
TTACAAATGGGGTGGAACGA

Downstream 100 bases:

>100_bases
TACACATTCATGAAGCCTCACCTGATTCACTCAAGGTGAGGCTCTTTTTTATAATCCAATCCTATCGAAGTCAATGACTT
GATCATTCACCATTTCTCCA

Product: 6-phosphogluconate dehydrogenase-like protein

Products: D-ribulose 5-phosphate; CO2; NADPH

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MEIGMIGLGKMGLNLALNLTDNGHRVVGYDPGNVSTSQFETKDSLQEVVSTLQAPRVVWVMVPAGDVTEHVLNDLHHLLS
PGDIVIDGGNSNYKESMRRSEHFKEKLIYLFDVGTSGGMEGARHGACTMIGGDLEAFGKIEQLFQDVSTDHGYLYAGPSG
SGHFLKMVHNGIEYGMMQAIAEGFEVLEKSPFDYDYEDVSRVWNHGSVIRSWLMELTESAFSKDAKLNDIRGVMHASGEG
KWTVETALEYDVPTPVIALSLMMRQRSLQDDTFSGKVVAALRNEFGGHAVEKKE

Sequences:

>Translated_294_residues
MEIGMIGLGKMGLNLALNLTDNGHRVVGYDPGNVSTSQFETKDSLQEVVSTLQAPRVVWVMVPAGDVTEHVLNDLHHLLS
PGDIVIDGGNSNYKESMRRSEHFKEKLIYLFDVGTSGGMEGARHGACTMIGGDLEAFGKIEQLFQDVSTDHGYLYAGPSG
SGHFLKMVHNGIEYGMMQAIAEGFEVLEKSPFDYDYEDVSRVWNHGSVIRSWLMELTESAFSKDAKLNDIRGVMHASGEG
KWTVETALEYDVPTPVIALSLMMRQRSLQDDTFSGKVVAALRNEFGGHAVEKKE
>Mature_294_residues
MEIGMIGLGKMGLNLALNLTDNGHRVVGYDPGNVSTSQFETKDSLQEVVSTLQAPRVVWVMVPAGDVTEHVLNDLHHLLS
PGDIVIDGGNSNYKESMRRSEHFKEKLIYLFDVGTSGGMEGARHGACTMIGGDLEAFGKIEQLFQDVSTDHGYLYAGPSG
SGHFLKMVHNGIEYGMMQAIAEGFEVLEKSPFDYDYEDVSRVWNHGSVIRSWLMELTESAFSKDAKLNDIRGVMHASGEG
KWTVETALEYDVPTPVIALSLMMRQRSLQDDTFSGKVVAALRNEFGGHAVEKKE

Specific function: May act as NAD-dependent 6-P-gluconate dehydrogenase [H]

COG id: COG1023

COG function: function code G; Predicted 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=315, Percent_Identity=36.5079365079365, Blast_Score=152, Evalue=2e-37,
Organism=Escherichia coli, GI1788341, Length=314, Percent_Identity=31.8471337579618, Blast_Score=150, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17542558, Length=292, Percent_Identity=35.2739726027397, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6321695, Length=295, Percent_Identity=33.5593220338983, Blast_Score=162, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6321977, Length=308, Percent_Identity=35.3896103896104, Blast_Score=160, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24639279, Length=289, Percent_Identity=37.0242214532872, Blast_Score=154, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR004849
- InterPro:   IPR006114
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: 1.1.1.44

Molecular weight: Translated: 32361; Mature: 32361

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIGMIGLGKMGLNLALNLTDNGHRVVGYDPGNVSTSQFETKDSLQEVVSTLQAPRVVWV
CCCCCEECCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
MVPAGDVTEHVLNDLHHLLSPGDIVIDGGNSNYKESMRRSEHFKEKLIYLFDVGTSGGME
EECCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCC
GARHGACTMIGGDLEAFGKIEQLFQDVSTDHGYLYAGPSGSGHFLKMVHNGIEYGMMQAI
CCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
AEGFEVLEKSPFDYDYEDVSRVWNHGSVIRSWLMELTESAFSKDAKLNDIRGVMHASGEG
HHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
KWTVETALEYDVPTPVIALSLMMRQRSLQDDTFSGKVVAALRNEFGGHAVEKKE
CEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MEIGMIGLGKMGLNLALNLTDNGHRVVGYDPGNVSTSQFETKDSLQEVVSTLQAPRVVWV
CCCCCEECCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
MVPAGDVTEHVLNDLHHLLSPGDIVIDGGNSNYKESMRRSEHFKEKLIYLFDVGTSGGME
EECCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCC
GARHGACTMIGGDLEAFGKIEQLFQDVSTDHGYLYAGPSGSGHFLKMVHNGIEYGMMQAI
CCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
AEGFEVLEKSPFDYDYEDVSRVWNHGSVIRSWLMELTESAFSKDAKLNDIRGVMHASGEG
HHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
KWTVETALEYDVPTPVIALSLMMRQRSLQDDTFSGKVVAALRNEFGGHAVEKKE
CEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.05 {6-phosphogluconate}} 0.01 {6-phosphogluconate}} [C]

Substrates: 6-phospho-D-gluconate; NADP+

Specific reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]