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The map label for this gene is bglH [H]

Identifier: 229916926

GI number: 229916926

Start: 1173842

End: 1175290

Strand: Direct

Name: bglH [H]

Synonym: EAT1b_1200

Alternate gene names: 229916926

Gene position: 1173842-1175290 (Clockwise)

Preceding gene: 229916925

Following gene: 229916932

Centisome position: 39.13

GC content: 48.72

Gene sequence:

>1449_bases
ATGAGTTTTCCAAAAGGATTTTTATGGGGTGGCGCCATTGCCGCCAACCAAGCAGAAGGCGCTTATGCAGAAGGGGGAAA
AGGTTTAACTACCGTCGACTTGTTGCCGACGGGTAAAAAACGCTTCGATGTCATGTTTGGAGAACTGCCATCATTAGAAC
CTATGCCCGGAGAGTTTTATCCTTCGCATGAAGCGATTGATTTTTACCATCGCTACAAAGAAGACATCGCTTTATTCGCT
GAGATGGGATTCAAGGCGCTTCGCCTCTCGATCGCATGGTCAAGAATCTTCCCGAACGGAGATGACGTGGAGCCGAACGA
GGAAGGTTTGCAGTTTTATGATGATGTCTTCGATGAACTATTAAAACATGGGATTGAACCAGTCGTGACAATCGCTCACT
TCGATGTACCTGTCAGCTTGATCAAAAAATATGGAAGCTGGCGCAATCGACGAGTCGTCGACTTCTTCGAGACATATGCG
AAGACCCTCTTCACCCGCTACAACGGTAAAGTGAAGTATTGGATGACGTTCAACGAGATCAATATGCTACTCCACCTCCC
ATTCATTGGAGCGGGCATCGTGTTCGAGGACGGAGAAGACAAGCAACAAGTGAAATATCAGGCGGCCCATCATCAACTCG
TCGCGAGTGCGAAAGCCGTCAAAGCAGCCCACGAAATCAATCCTGATCTACAGGTGGGTTGTATGCTTGCTGCTGGTCAA
ACGTATGCCTATTCGTGTAACCCGAATGATGTGTTAGATGCAATGGACAAAGACCGTGAATCGTTCTTCTTCATCGACGT
CCAATCACGTGGAGAGTACCCGGGATATGCCAAACGATATCTCGAGGAGCAAGGTATTACGCTTCAGATAGAAGAAGGTG
ACCTCGAACTGTTGAAAGAGCATACGGTCGACTACATCGGCTTCAGCTATTATGCAAGTCGGACGACGAGTACGGATCCA
GAGATAAATCAGTCGACCGAAGGAAACATTTTCAGTTCACTTGAGAACCCGTTCCTCGAGAAATCGGAATGGGGCTGGAC
AATTGACCCGACCGGTTTCCGGATCACGGCGAACCAACTGTATGACCGCTATCAAAAGCCGCTATTCGTCGTCGAGAACG
GACTCGGTGCCGTCGATACACCGGATGCGACTGGATATGTCGAAGACGATTATCGCATCGACTATATGGCGAAACATATC
GAACAGATGCACGAGGCCATCAAGGACGGTGTCGAGATCATCGGCTACACAAGCTGGGGTCCGATTGACTTGGTGAGTGC
GTCGACCGGTGAGATGAAGAAACGCTACGGCTTCATCTATGTCGATAAAGACAATGAAGGCAACGGGACGCTCACACGTT
CCAAGAAAAAGAGCTTCGATTGGTATAAGCAAGTGATTGCGACGAACGGGGCGGACGTCACTACTCCTGTTCAAACTACT
AAATCTTGA

Upstream 100 bases:

>100_bases
AACTACGCCTCACATGTCCAGACGGGCGATCCGATTTTCATCATCTAATGAATCAAGTGGGAGGATTTTTCCTCCCACTA
ATATAGAAAGGATGGATACG

Downstream 100 bases:

>100_bases
TTAAAAAGGAGGCAACCGACTTAAATCGGTTGCCTCCTTTTTGAATGGTAGTGATGAATTTATTCCACCCCAAATCGATA
CACCGTGCGTGAGTGATAGA

Product: glycoside hydrolase family 1

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MSFPKGFLWGGAIAANQAEGAYAEGGKGLTTVDLLPTGKKRFDVMFGELPSLEPMPGEFYPSHEAIDFYHRYKEDIALFA
EMGFKALRLSIAWSRIFPNGDDVEPNEEGLQFYDDVFDELLKHGIEPVVTIAHFDVPVSLIKKYGSWRNRRVVDFFETYA
KTLFTRYNGKVKYWMTFNEINMLLHLPFIGAGIVFEDGEDKQQVKYQAAHHQLVASAKAVKAAHEINPDLQVGCMLAAGQ
TYAYSCNPNDVLDAMDKDRESFFFIDVQSRGEYPGYAKRYLEEQGITLQIEEGDLELLKEHTVDYIGFSYYASRTTSTDP
EINQSTEGNIFSSLENPFLEKSEWGWTIDPTGFRITANQLYDRYQKPLFVVENGLGAVDTPDATGYVEDDYRIDYMAKHI
EQMHEAIKDGVEIIGYTSWGPIDLVSASTGEMKKRYGFIYVDKDNEGNGTLTRSKKKSFDWYKQVIATNGADVTTPVQTT
KS

Sequences:

>Translated_482_residues
MSFPKGFLWGGAIAANQAEGAYAEGGKGLTTVDLLPTGKKRFDVMFGELPSLEPMPGEFYPSHEAIDFYHRYKEDIALFA
EMGFKALRLSIAWSRIFPNGDDVEPNEEGLQFYDDVFDELLKHGIEPVVTIAHFDVPVSLIKKYGSWRNRRVVDFFETYA
KTLFTRYNGKVKYWMTFNEINMLLHLPFIGAGIVFEDGEDKQQVKYQAAHHQLVASAKAVKAAHEINPDLQVGCMLAAGQ
TYAYSCNPNDVLDAMDKDRESFFFIDVQSRGEYPGYAKRYLEEQGITLQIEEGDLELLKEHTVDYIGFSYYASRTTSTDP
EINQSTEGNIFSSLENPFLEKSEWGWTIDPTGFRITANQLYDRYQKPLFVVENGLGAVDTPDATGYVEDDYRIDYMAKHI
EQMHEAIKDGVEIIGYTSWGPIDLVSASTGEMKKRYGFIYVDKDNEGNGTLTRSKKKSFDWYKQVIATNGADVTTPVQTT
KS
>Mature_481_residues
SFPKGFLWGGAIAANQAEGAYAEGGKGLTTVDLLPTGKKRFDVMFGELPSLEPMPGEFYPSHEAIDFYHRYKEDIALFAE
MGFKALRLSIAWSRIFPNGDDVEPNEEGLQFYDDVFDELLKHGIEPVVTIAHFDVPVSLIKKYGSWRNRRVVDFFETYAK
TLFTRYNGKVKYWMTFNEINMLLHLPFIGAGIVFEDGEDKQQVKYQAAHHQLVASAKAVKAAHEINPDLQVGCMLAAGQT
YAYSCNPNDVLDAMDKDRESFFFIDVQSRGEYPGYAKRYLEEQGITLQIEEGDLELLKEHTVDYIGFSYYASRTTSTDPE
INQSTEGNIFSSLENPFLEKSEWGWTIDPTGFRITANQLYDRYQKPLFVVENGLGAVDTPDATGYVEDDYRIDYMAKHIE
QMHEAIKDGVEIIGYTSWGPIDLVSASTGEMKKRYGFIYVDKDNEGNGTLTRSKKKSFDWYKQVIATNGADVTTPVQTTK
S

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=497, Percent_Identity=30.784708249497, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI32481206, Length=491, Percent_Identity=28.3095723014257, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI13273313, Length=506, Percent_Identity=25.6916996047431, Blast_Score=159, Evalue=7e-39,
Organism=Homo sapiens, GI24497614, Length=491, Percent_Identity=28.9205702647658, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI28376633, Length=489, Percent_Identity=25.3578732106339, Blast_Score=138, Evalue=1e-32,
Organism=Escherichia coli, GI1789070, Length=471, Percent_Identity=62.4203821656051, Blast_Score=644, Evalue=0.0,
Organism=Escherichia coli, GI2367270, Length=470, Percent_Identity=56.8085106382979, Blast_Score=563, Evalue=1e-162,
Organism=Escherichia coli, GI2367174, Length=476, Percent_Identity=52.7310924369748, Blast_Score=533, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI17552856, Length=482, Percent_Identity=28.4232365145228, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17539390, Length=491, Percent_Identity=28.9205702647658, Blast_Score=168, Evalue=7e-42,
Organism=Drosophila melanogaster, GI21356577, Length=501, Percent_Identity=25.1497005988024, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54597; Mature: 54466

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPKGFLWGGAIAANQAEGAYAEGGKGLTTVDLLPTGKKRFDVMFGELPSLEPMPGEFY
CCCCCCCEECCEEECCCCCCCCCCCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCCCCC
PSHEAIDFYHRYKEDIALFAEMGFKALRLSIAWSRIFPNGDDVEPNEEGLQFYDDVFDEL
CCCHHHHHHHHHHHHHHHHHHHCHHHEEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHHH
LKHGIEPVVTIAHFDVPVSLIKKYGSWRNRRVVDFFETYAKTLFTRYNGKVKYWMTFNEI
HHCCCCCEEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEHEE
NMLLHLPFIGAGIVFEDGEDKQQVKYQAAHHQLVASAKAVKAAHEINPDLQVGCMLAAGQ
EEEEEECEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
TYAYSCNPNDVLDAMDKDRESFFFIDVQSRGEYPGYAKRYLEEQGITLQIEEGDLELLKE
EEEEECCCHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHH
HTVDYIGFSYYASRTTSTDPEINQSTEGNIFSSLENPFLEKSEWGWTIDPTGFRITANQL
HHHHHEEHHHEECCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCEEECCCCEEEEHHHH
YDRYQKPLFVVENGLGAVDTPDATGYVEDDYRIDYMAKHIEQMHEAIKDGVEIIGYTSWG
HHHHCCCEEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCC
PIDLVSASTGEMKKRYGFIYVDKDNEGNGTLTRSKKKSFDWYKQVIATNGADVTTPVQTT
CEEEEECCCHHHHHHCCEEEEECCCCCCCCEECCCHHHHHHHHHHHHCCCCCCCCCCCCC
KS
CC
>Mature Secondary Structure 
SFPKGFLWGGAIAANQAEGAYAEGGKGLTTVDLLPTGKKRFDVMFGELPSLEPMPGEFY
CCCCCCEECCEEECCCCCCCCCCCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCCCCC
PSHEAIDFYHRYKEDIALFAEMGFKALRLSIAWSRIFPNGDDVEPNEEGLQFYDDVFDEL
CCCHHHHHHHHHHHHHHHHHHHCHHHEEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHHH
LKHGIEPVVTIAHFDVPVSLIKKYGSWRNRRVVDFFETYAKTLFTRYNGKVKYWMTFNEI
HHCCCCCEEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEHEE
NMLLHLPFIGAGIVFEDGEDKQQVKYQAAHHQLVASAKAVKAAHEINPDLQVGCMLAAGQ
EEEEEECEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
TYAYSCNPNDVLDAMDKDRESFFFIDVQSRGEYPGYAKRYLEEQGITLQIEEGDLELLKE
EEEEECCCHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHH
HTVDYIGFSYYASRTTSTDPEINQSTEGNIFSSLENPFLEKSEWGWTIDPTGFRITANQL
HHHHHEEHHHEECCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCEEECCCCEEEEHHHH
YDRYQKPLFVVENGLGAVDTPDATGYVEDDYRIDYMAKHIEQMHEAIKDGVEIIGYTSWG
HHHHCCCEEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCC
PIDLVSASTGEMKKRYGFIYVDKDNEGNGTLTRSKKKSFDWYKQVIATNGADVTTPVQTT
CEEEEECCCHHHHHHCCEEEEECCCCCCCCEECCCHHHHHHHHHHHHCCCCCCCCCCCCC
KS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377 [H]