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The map label for this gene is mro [H]

Identifier: 229916927

GI number: 229916927

Start: 1175350

End: 1176312

Strand: Reverse

Name: mro [H]

Synonym: EAT1b_1201

Alternate gene names: 229916927

Gene position: 1176312-1175350 (Counterclockwise)

Preceding gene: 229916928

Following gene: 229916924

Centisome position: 39.21

GC content: 54.72

Gene sequence:

>963_bases
ATGAAACAAGCGACGATTCAAAACGCCAACGGCATGATACTATCCGCCATTGACTATGGCTGTGCGATGACGGAACTGAC
GGCCCCGGACCGGGAAGGGAATTTTGACTCGGTCATCTTGAAGTACGGGGACGTCTCTCAATACTTAGAAAATCCCGTAT
ATCTCGGGTTGGTCGTCGGGCGGATTGCCGGACGGATTCGTGACGCAGAGATTGAGGGTGTCGCTTTGACCCCAAGCGAG
GCGCCCCATCATATCCACGGAGGTGACAAAGGCATCACGGCCCGTCACTGGGAGATGGACGCCGACGAACAGTGCATTCA
GTTCACATATCTCAGTCCGGACGGGGAAGAAGGATACCCGGGGAACGTCTTCTTTAAAGTGTTATATGAGCTGACGGATG
ACAATGAACTGATTGTCACGATGACAGCGGAAACGGACCAACGGACGTGGGTCAACTTGAACCATCATAACTACTTCAAT
CTCGGCGGACGCCCGACCATCCACGACCATGAGCTGACGCTACCAGCCGATTTGGTCGGGGTGCTCGATGCAGAGTCACT
ACCGACAGGCGAGTTGCGGGATGTGAGCGGAACACCGTTCGACTTCCGAGACGGAAAAACGGTCCGAGAGGCGCTCGTGT
CGGGAGACGAGGCGATTGAAAGGGCGAGCGGTCTCGATCATCCGTTTATCTTGAAGGATGAACCGATTCGATTGCATGAC
CCGGTGAGCGGACGGACGATGACGGTCGAAACGAATCAACCGGTCATGGTCGTTTATACGGGAAACTTCCTCAGTGAAGA
GACACCGGTGACGCTCAATGGTCGACAGAAACATAGCGCGATTTGTCTCGAGGCACAGGCGTATCCGGACGCTCCGAATC
ATCCGGACATCGCGACCTCCATCGAACTGAAACCGGGTGAGCTCTATCACTCACGCACGGTGTATCGATTTGGGGTGGAA
TAA

Upstream 100 bases:

>100_bases
ACCGATTGCGGTGAATCCGCCTCATTTGCCAGAAAAAAACTGGCGAGGGCGCTGGAAGTGGTAAATCAATTGCCCGATGA
CGGGGTAGAAAGGTGATGGC

Downstream 100 bases:

>100_bases
ATTCATCACTACCATTCAAAAAGGAGGCAACCGATTTAAGTCGGTTGCCTCCTTTTTAATCAAGATTTAGTAGTTTGAAC
AGGAGTAGTGACGTCCGCCC

Product: Aldose 1-epimerase

Products: NA

Alternate protein names: Galactose mutarotase; Type-1 mutarotase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKQATIQNANGMILSAIDYGCAMTELTAPDREGNFDSVILKYGDVSQYLENPVYLGLVVGRIAGRIRDAEIEGVALTPSE
APHHIHGGDKGITARHWEMDADEQCIQFTYLSPDGEEGYPGNVFFKVLYELTDDNELIVTMTAETDQRTWVNLNHHNYFN
LGGRPTIHDHELTLPADLVGVLDAESLPTGELRDVSGTPFDFRDGKTVREALVSGDEAIERASGLDHPFILKDEPIRLHD
PVSGRTMTVETNQPVMVVYTGNFLSEETPVTLNGRQKHSAICLEAQAYPDAPNHPDIATSIELKPGELYHSRTVYRFGVE

Sequences:

>Translated_320_residues
MKQATIQNANGMILSAIDYGCAMTELTAPDREGNFDSVILKYGDVSQYLENPVYLGLVVGRIAGRIRDAEIEGVALTPSE
APHHIHGGDKGITARHWEMDADEQCIQFTYLSPDGEEGYPGNVFFKVLYELTDDNELIVTMTAETDQRTWVNLNHHNYFN
LGGRPTIHDHELTLPADLVGVLDAESLPTGELRDVSGTPFDFRDGKTVREALVSGDEAIERASGLDHPFILKDEPIRLHD
PVSGRTMTVETNQPVMVVYTGNFLSEETPVTLNGRQKHSAICLEAQAYPDAPNHPDIATSIELKPGELYHSRTVYRFGVE
>Mature_320_residues
MKQATIQNANGMILSAIDYGCAMTELTAPDREGNFDSVILKYGDVSQYLENPVYLGLVVGRIAGRIRDAEIEGVALTPSE
APHHIHGGDKGITARHWEMDADEQCIQFTYLSPDGEEGYPGNVFFKVLYELTDDNELIVTMTAETDQRTWVNLNHHNYFN
LGGRPTIHDHELTLPADLVGVLDAESLPTGELRDVSGTPFDFRDGKTVREALVSGDEAIERASGLDHPFILKDEPIRLHD
PVSGRTMTVETNQPVMVVYTGNFLSEETPVTLNGRQKHSAICLEAQAYPDAPNHPDIATSIELKPGELYHSRTVYRFGVE

Specific function: Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose [H]

COG id: COG2017

COG function: function code G; Galactose mutarotase and related enzymes

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldose epimerase family [H]

Homologues:

Organism=Homo sapiens, GI20270355, Length=323, Percent_Identity=38.6996904024768, Blast_Score=199, Evalue=4e-51,
Organism=Escherichia coli, GI1786971, Length=329, Percent_Identity=31.0030395136778, Blast_Score=170, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17557428, Length=329, Percent_Identity=28.5714285714286, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI115533334, Length=329, Percent_Identity=28.5714285714286, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24659048, Length=346, Percent_Identity=33.8150289017341, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24668278, Length=339, Percent_Identity=31.858407079646, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24668282, Length=347, Percent_Identity=32.5648414985591, Blast_Score=161, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24583720, Length=335, Percent_Identity=30.4477611940298, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24641876, Length=345, Percent_Identity=28.695652173913, Blast_Score=137, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018052
- InterPro:   IPR008183
- InterPro:   IPR015443
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.3 [H]

Molecular weight: Translated: 35435; Mature: 35435

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQATIQNANGMILSAIDYGCAMTELTAPDREGNFDSVILKYGDVSQYLENPVYLGLVVG
CCCCEEECCCCCEEEEECCCEEEEECCCCCCCCCCCEEEEEECCHHHHHCCCEEEEHHHH
RIAGRIRDAEIEGVALTPSEAPHHIHGGDKGITARHWEMDADEQCIQFTYLSPDGEEGYP
HHHCCEECCEECEEEECCCCCCCEECCCCCCCEEEECCCCCCCCEEEEEEECCCCCCCCC
GNVFFKVLYELTDDNELIVTMTAETDQRTWVNLNHHNYFNLGGRPTIHDHELTLPADLVG
CCEEEEEEEEECCCCEEEEEEECCCCCCEEEEECCCCEEECCCCCCCCCCEEECCHHHHE
VLDAESLPTGELRDVSGTPFDFRDGKTVREALVSGDEAIERASGLDHPFILKDEPIRLHD
EECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCEEECCCCEEEEC
PVSGRTMTVETNQPVMVVYTGNFLSEETPVTLNGRQKHSAICLEAQAYPDAPNHPDIATS
CCCCCEEEEECCCCEEEEEECCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCCCCCEEE
IELKPGELYHSRTVYRFGVE
EEECCCCEECCCEEEEECCC
>Mature Secondary Structure
MKQATIQNANGMILSAIDYGCAMTELTAPDREGNFDSVILKYGDVSQYLENPVYLGLVVG
CCCCEEECCCCCEEEEECCCEEEEECCCCCCCCCCCEEEEEECCHHHHHCCCEEEEHHHH
RIAGRIRDAEIEGVALTPSEAPHHIHGGDKGITARHWEMDADEQCIQFTYLSPDGEEGYP
HHHCCEECCEECEEEECCCCCCCEECCCCCCCEEEECCCCCCCCEEEEEEECCCCCCCCC
GNVFFKVLYELTDDNELIVTMTAETDQRTWVNLNHHNYFNLGGRPTIHDHELTLPADLVG
CCEEEEEEEEECCCCEEEEEEECCCCCCEEEEECCCCEEECCCCCCCCCCEEECCHHHHE
VLDAESLPTGELRDVSGTPFDFRDGKTVREALVSGDEAIERASGLDHPFILKDEPIRLHD
EECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCEEECCCCEEEEC
PVSGRTMTVETNQPVMVVYTGNFLSEETPVTLNGRQKHSAICLEAQAYPDAPNHPDIATS
CCCCCEEEEECCCCEEEEEECCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCCCCCEEE
IELKPGELYHSRTVYRFGVE
EEECCCCEECCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3012466; 3531172 [H]