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The map label for this gene is wecB [H]

Identifier: 229916920

GI number: 229916920

Start: 1164114

End: 1165265

Strand: Reverse

Name: wecB [H]

Synonym: EAT1b_1193

Alternate gene names: 229916920

Gene position: 1165265-1164114 (Counterclockwise)

Preceding gene: 229916921

Following gene: 229916919

Centisome position: 38.84

GC content: 55.21

Gene sequence:

>1152_bases
ATGAAACGACTCAAGGTCATGACGATTGTTGGTACCAGACCCGAAATCATTCGATTGTCCGCCGTGATGGCACGTCTCGA
AGCCTCCGAGGCAATCGACCATGTGCTCGTTCATACGGGACAAAACTATGACTATGAATTGAATCAGATTTTCTTTGAAG
ACTTCGGACTCCGGACACCGGACTATGTGTTAGACGCCTCAGCGGATGGTCCGATGGCGACGATTGGGAATATCCTCATC
GCTATCGATCCCGTGCTCACGTCCGAACGTCCGGACGCGGTCTTGTTACTCGGGGACACGAACAGCTGTCTCGCAGCCAT
CGCCGCGAAACGCCACCACATCCCCATCTTTCACATGGAGGCGGGGAATCGCTGTTTTGACGAACGGGTCCCAGAGGAGA
CGAATCGTCGCATCGTCGACCATATCGCCGACATCAACCTGACCTATAGCGACATCGCACGCGAGTATCTGCTTCGTGAA
GGGTTACCGGCGGACCGCATCATCAAGACGGGGAGCCCGATGTACGAGGTACTCCACCGTCAACGGGAGAAGATCGAACG
GTCAGACGTGCTCGAGCGGCTCGACTTGGAGCGAGATGCCTATTTCGTCGTATCGGCCCATCGCGATGAAAACATCAGTG
ATGACGAGAACTTCTTTGATCTGGTAGATACGCTCAATGCGGTCGCGACCACGTATCAGCTCCCTCTCATCGTCAGCACC
CACCCCCGGACGGCAAAACGTATTCGTGAGAGCGGGGTGCGTCTCCATCCGAACATTCGCACCCTCAAACCGCTCGGCTT
CAGTGACTACGTCCACCTGCAACTCCATGCAAAGGCCGTGTTGTCGGACAGCGGAACCATTAGTGAAGAGAGCTCGATTC
TTGGAATCAAAGGATTGAATATCCGACAAGCGCATGAGCGTCCGGAGGCGATGGAGGAAGGGGCGGCGATGATGGTCGGA
TTGAAGCGGGAGCGAGTGCTTCAGGCGCTTCGAATCTTAGAAGAGACGGATGGCTCGATGCGACTCGTGAGCGATTACGC
CATGCCGAACGTCTCCGATAAAGTGCTCCGCATCTTGTTGTCCTACACGGACTATGTGATGCGAGAGGTGTGGAAACAGC
ACACGGTGTCGACCGAGAAGAAAGAGGTGTGA

Upstream 100 bases:

>100_bases
TCGCATTTGATGAGACGGAGAAAGCCATGTTCCGCCAAGTGTTCGCTCAATTGAAACTACGCATCCTATCCATTCACCAC
ACATCCTAGGAGGGAACAAG

Downstream 100 bases:

>100_bases
GCCATGGACTATATGACGTTCAAACGAATCTTTGACGGGACGCTCAGCGGAGTGGCGCTCCTTCTTCTCGCACCGATTCT
GCTCCTTATCGCCCTCTTGA

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKRLKVMTIVGTRPEIIRLSAVMARLEASEAIDHVLVHTGQNYDYELNQIFFEDFGLRTPDYVLDASADGPMATIGNILI
AIDPVLTSERPDAVLLLGDTNSCLAAIAAKRHHIPIFHMEAGNRCFDERVPEETNRRIVDHIADINLTYSDIAREYLLRE
GLPADRIIKTGSPMYEVLHRQREKIERSDVLERLDLERDAYFVVSAHRDENISDDENFFDLVDTLNAVATTYQLPLIVST
HPRTAKRIRESGVRLHPNIRTLKPLGFSDYVHLQLHAKAVLSDSGTISEESSILGIKGLNIRQAHERPEAMEEGAAMMVG
LKRERVLQALRILEETDGSMRLVSDYAMPNVSDKVLRILLSYTDYVMREVWKQHTVSTEKKEV

Sequences:

>Translated_383_residues
MKRLKVMTIVGTRPEIIRLSAVMARLEASEAIDHVLVHTGQNYDYELNQIFFEDFGLRTPDYVLDASADGPMATIGNILI
AIDPVLTSERPDAVLLLGDTNSCLAAIAAKRHHIPIFHMEAGNRCFDERVPEETNRRIVDHIADINLTYSDIAREYLLRE
GLPADRIIKTGSPMYEVLHRQREKIERSDVLERLDLERDAYFVVSAHRDENISDDENFFDLVDTLNAVATTYQLPLIVST
HPRTAKRIRESGVRLHPNIRTLKPLGFSDYVHLQLHAKAVLSDSGTISEESSILGIKGLNIRQAHERPEAMEEGAAMMVG
LKRERVLQALRILEETDGSMRLVSDYAMPNVSDKVLRILLSYTDYVMREVWKQHTVSTEKKEV
>Mature_383_residues
MKRLKVMTIVGTRPEIIRLSAVMARLEASEAIDHVLVHTGQNYDYELNQIFFEDFGLRTPDYVLDASADGPMATIGNILI
AIDPVLTSERPDAVLLLGDTNSCLAAIAAKRHHIPIFHMEAGNRCFDERVPEETNRRIVDHIADINLTYSDIAREYLLRE
GLPADRIIKTGSPMYEVLHRQREKIERSDVLERLDLERDAYFVVSAHRDENISDDENFFDLVDTLNAVATTYQLPLIVST
HPRTAKRIRESGVRLHPNIRTLKPLGFSDYVHLQLHAKAVLSDSGTISEESSILGIKGLNIRQAHERPEAMEEGAAMMVG
LKRERVLQALRILEETDGSMRLVSDYAMPNVSDKVLRILLSYTDYVMREVWKQHTVSTEKKEV

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=352, Percent_Identity=30.6818181818182, Blast_Score=126, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 43480; Mature: 43480

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLKVMTIVGTRPEIIRLSAVMARLEASEAIDHVLVHTGQNYDYELNQIFFEDFGLRTP
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCC
DYVLDASADGPMATIGNILIAIDPVLTSERPDAVLLLGDTNSCLAAIAAKRHHIPIFHME
CEEEECCCCCCHHHHCCEEEEECCHHCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEC
AGNRCFDERVPEETNRRIVDHIADINLTYSDIAREYLLREGLPADRIIKTGSPMYEVLHR
CCCCHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHH
QREKIERSDVLERLDLERDAYFVVSAHRDENISDDENFFDLVDTLNAVATTYQLPLIVST
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHEECEEEEEC
HPRTAKRIRESGVRLHPNIRTLKPLGFSDYVHLQLHAKAVLSDSGTISEESSILGIKGLN
CCHHHHHHHHCCCEECCCCCEECCCCCCCEEEEEEEEEEEECCCCCCCCCCCEEEECCCC
IRQAHERPEAMEEGAAMMVGLKRERVLQALRILEETDGSMRLVSDYAMPNVSDKVLRILL
HHHHHCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHH
SYTDYVMREVWKQHTVSTEKKEV
HHHHHHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure
MKRLKVMTIVGTRPEIIRLSAVMARLEASEAIDHVLVHTGQNYDYELNQIFFEDFGLRTP
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCC
DYVLDASADGPMATIGNILIAIDPVLTSERPDAVLLLGDTNSCLAAIAAKRHHIPIFHME
CEEEECCCCCCHHHHCCEEEEECCHHCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEC
AGNRCFDERVPEETNRRIVDHIADINLTYSDIAREYLLREGLPADRIIKTGSPMYEVLHR
CCCCHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHH
QREKIERSDVLERLDLERDAYFVVSAHRDENISDDENFFDLVDTLNAVATTYQLPLIVST
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHEECEEEEEC
HPRTAKRIRESGVRLHPNIRTLKPLGFSDYVHLQLHAKAVLSDSGTISEESSILGIKGLN
CCHHHHHHHHCCCEECCCCCEECCCCCCCEEEEEEEEEEEECCCCCCCCCCCEEEECCCC
IRQAHERPEAMEEGAAMMVGLKRERVLQALRILEETDGSMRLVSDYAMPNVSDKVLRILL
HHHHHCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHH
SYTDYVMREVWKQHTVSTEKKEV
HHHHHHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]