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The map label for this gene is wprA [H]

Identifier: 229916835

GI number: 229916835

Start: 1085401

End: 1088088

Strand: Reverse

Name: wprA [H]

Synonym: EAT1b_1108

Alternate gene names: 229916835

Gene position: 1088088-1085401 (Counterclockwise)

Preceding gene: 229916836

Following gene: 229916834

Centisome position: 36.27

GC content: 58.48

Gene sequence:

>2688_bases
ATGAAAGCACGATTCAAGCAGTTCGTGGCGATGGTGACGGTTCTCGTCCTCGTCCTTTCGTTCCTGCCGCCAGCACTCGC
TGACAGCGGAAACGGGATGACCAATGCCACATTACTCACTCCGGGGGAAGCGGTCGAATTCACGACCGGCACGGACCCGG
TCAACACGTATTGGTTCAAGATGGAACGAGAGACGTCCGCGATGACACATATGGAAGTCACGTTCGAATCTTCGAAGCTC
GCGAACATCAGCGTCTATCCGAGCGCCGACATGGCGGCGAAGGATGAGACGTTCGACCGTTACCGCGCGAGCGCGACGAA
GGAAGAGGAAGAACAGACGGCCAAGATCGAATTCCCGTTCGCATGGGAAGGTCCATACTACATCAAGGTCGAGTATATGC
CGATGGATCTCGGAGAAGAAATTCCAGGCGAAGAGATTCCAGGGGATGTGCTCCCGGTCGATGGGGAAGAGCCGACAGAC
CCAGGCATGCCGGATCTCGCGTCAGACATCAAGCTCGTCGTCAACCCGGTCAAACTCCCGGTCAAATACGAGCAGGTCGG
CGGCGACATGTGTGCCGTCGAGTCGATCGTCCAACCGGCACCGGAACGTGACTCGATGCTCAAGCTCATCCGTCGCGTCC
AAAGTGAAGTACTCGGCACGTCACAGAAAGGTCGCGACTTGTCGGCCCTTTACTACCGTGCCTCACCGTATATCGTCAAA
GCGATCACGTTTGACGGCGAGAAGCGCAAAGCTGCCCTCACCGACTTGAAGACGCTCCGTCCGTTGTTGACGGCACTCGT
CGACAAGAAGGCGTATACGCTCAAAACCCAGGACGCGGCGGCAATCAACCGTCTTCACGCCTTGGTCGACGCAAGCGTAC
CGACTGCGCTACAAGGCGAAATCGGTGAGATCGCGACAGCGCTCGAGATGGACTCGCTCGCCGGGACTCCGGTGACGGAC
CTCTTCGGCAAAGTCGGGATGACGATTCAAACGGACGGCAGTGACGCACCGCGTTACATCGTCAAATACAAATCGTCACC
AAACACATCGATTGGCAAGATGAACGCGATGAGCGACGTCTCGGCCGAGCGTATCGCCATCGGGAAACCGTCTGATTACT
TCGCGCTCGTCGATGTAGAAGAAGCGTCGACGAAGATGCAGGCTCAGGCGAAGTCGACGCTCGAGTCGGACCGTAACGTC
GAGTATATCGAGCCGGTCCAGACGTATCAGTCGTTCGCGACCGACGTCAGCCTCGACTACCAATGGGCGATCAACCAGAA
GTCGGTGCTCGAGCCGTTCGCGAATGCAGGGATCGGCCTCGACAAGTATGAGGCGTTGAACTTGCCGAAACGCTCGATCA
AAGTAGCCGTCCTCGACACTGGGGTCGACCATCGTCTCCTTGACCTAAAAGGTAAGGTCGATGTCGCAAACGCGAAGAAC
TTCGTCGACCCGAACGGGGAAGGCGACGCGATCGATGACCACGGTCACGGGACGCACGTCGCCGGCGTCATCGGTGCGAC
ACGTGACAACGGCGTCTCGATGCGCGGGATCGTCCCGAACGTCTCGATTCTGCCGGTGAAAGTGCTCGATGCGGGCGGTT
CTGGGGACACGGACCAAATCGCACTCGGGATCAAGTATGCGGTCGACGCGGGGGCGAAAGTCATCAACATGAGCCTTGGC
GGCAACGAGAGCCGTACGCTCGGTTACATGTTGAAGTATGCGTATGACCGTGGCGTCGTCATCGTGGCGGCGACAGGGAA
CGATGCGCAGTCACGCGTGTCGTACCCGGCATCATCGAAATACACGATCTCGGTCGGCGCGACAAACGCCTTCGGGATCG
TCTCGGATTACTCGAACTACGGAATCGGGGTCGACGTCGTCGCACCGGGCTCGAAAGTAGCGAGTCTCGTACCGGACGGG
AACGTTGTCTATATGGACGGGACGAGCATGGCGACACCACACGTCGCTGCAACCGTCGCGCTCCTCAAGTCGTATCACCC
AGATCTTTCGGTCGAAGACGTACGGACGCTCTTGCAGCGGACGGCAGACCCGATCGCCTTCTCGGGTGGGGACGCACCGT
ACGACCCACGCATGAGTGACGGGTTCGAGTATGTGTTAGAAGAATTGGGCATGACGCTCCCGGCGTATTACAACCCGGTG
AGCGGGTTCGGGAAGGCGAACGTCTACCGCGCCGAGTCGATGCTCAAATTGAACGCCTCTGGCGCGAACGCACAGGACAA
TTCTACGACGTTCAAGGCGAAAGTCACGTCGGGGACGACGGTCCGCGTGTATAAAGGAGAGAAGTTGATCGGACGAGGCA
CGTCGAAACAGACGATGGCGGCCTTCTCGATTCAACCGCAAAAAGCAGGAGCGGTCCTTCGCGTCGTCTATACGAACGGG
AAGTATGAGACGAGCGAACGTGTCGTCGTGAAAGCCGGCGCACGTCCAGGGCAACCGACGGTGAACACGCTCCGTTCTGG
CGCGAAGTCGGTCACGGGTCGCGGTGAAGCCGGGATGCGTGTCGTCGTCCGCAACAGCAACTATCAACTGTTGGGACGCG
GAACGGTCCTCCCGAACGGCACGTTCTCTGTGAAGACACGTGCGCTCAAGAAAGGCGAGACGATCAACGTCCACATCGAG
GACTTGAAAGGTCGCCCAGGAAAAATGAGCAAGACGACTGTACGATAA

Upstream 100 bases:

>100_bases
CTTGTCGAAACATTTTTGTTACATTTTTGAAACATAAACCGATAATTATCGTAGAACGATGTGGGGCACACGCTCCAAAA
CAAACGAAAGAGGGGAAAAC

Downstream 100 bases:

>100_bases
GAGAATTCAATAGAAGAGACGGGTATGCCGAGTGATCGGGATACCCGTTTTTTGATGGGATGAGAGGAGACAAAATAAAA
GAAGAGGTCGAAACCCCCTC

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: CWBP23; CWBP52 [H]

Number of amino acids: Translated: 895; Mature: 895

Protein sequence:

>895_residues
MKARFKQFVAMVTVLVLVLSFLPPALADSGNGMTNATLLTPGEAVEFTTGTDPVNTYWFKMERETSAMTHMEVTFESSKL
ANISVYPSADMAAKDETFDRYRASATKEEEEQTAKIEFPFAWEGPYYIKVEYMPMDLGEEIPGEEIPGDVLPVDGEEPTD
PGMPDLASDIKLVVNPVKLPVKYEQVGGDMCAVESIVQPAPERDSMLKLIRRVQSEVLGTSQKGRDLSALYYRASPYIVK
AITFDGEKRKAALTDLKTLRPLLTALVDKKAYTLKTQDAAAINRLHALVDASVPTALQGEIGEIATALEMDSLAGTPVTD
LFGKVGMTIQTDGSDAPRYIVKYKSSPNTSIGKMNAMSDVSAERIAIGKPSDYFALVDVEEASTKMQAQAKSTLESDRNV
EYIEPVQTYQSFATDVSLDYQWAINQKSVLEPFANAGIGLDKYEALNLPKRSIKVAVLDTGVDHRLLDLKGKVDVANAKN
FVDPNGEGDAIDDHGHGTHVAGVIGATRDNGVSMRGIVPNVSILPVKVLDAGGSGDTDQIALGIKYAVDAGAKVINMSLG
GNESRTLGYMLKYAYDRGVVIVAATGNDAQSRVSYPASSKYTISVGATNAFGIVSDYSNYGIGVDVVAPGSKVASLVPDG
NVVYMDGTSMATPHVAATVALLKSYHPDLSVEDVRTLLQRTADPIAFSGGDAPYDPRMSDGFEYVLEELGMTLPAYYNPV
SGFGKANVYRAESMLKLNASGANAQDNSTTFKAKVTSGTTVRVYKGEKLIGRGTSKQTMAAFSIQPQKAGAVLRVVYTNG
KYETSERVVVKAGARPGQPTVNTLRSGAKSVTGRGEAGMRVVVRNSNYQLLGRGTVLPNGTFSVKTRALKKGETINVHIE
DLKGRPGKMSKTTVR

Sequences:

>Translated_895_residues
MKARFKQFVAMVTVLVLVLSFLPPALADSGNGMTNATLLTPGEAVEFTTGTDPVNTYWFKMERETSAMTHMEVTFESSKL
ANISVYPSADMAAKDETFDRYRASATKEEEEQTAKIEFPFAWEGPYYIKVEYMPMDLGEEIPGEEIPGDVLPVDGEEPTD
PGMPDLASDIKLVVNPVKLPVKYEQVGGDMCAVESIVQPAPERDSMLKLIRRVQSEVLGTSQKGRDLSALYYRASPYIVK
AITFDGEKRKAALTDLKTLRPLLTALVDKKAYTLKTQDAAAINRLHALVDASVPTALQGEIGEIATALEMDSLAGTPVTD
LFGKVGMTIQTDGSDAPRYIVKYKSSPNTSIGKMNAMSDVSAERIAIGKPSDYFALVDVEEASTKMQAQAKSTLESDRNV
EYIEPVQTYQSFATDVSLDYQWAINQKSVLEPFANAGIGLDKYEALNLPKRSIKVAVLDTGVDHRLLDLKGKVDVANAKN
FVDPNGEGDAIDDHGHGTHVAGVIGATRDNGVSMRGIVPNVSILPVKVLDAGGSGDTDQIALGIKYAVDAGAKVINMSLG
GNESRTLGYMLKYAYDRGVVIVAATGNDAQSRVSYPASSKYTISVGATNAFGIVSDYSNYGIGVDVVAPGSKVASLVPDG
NVVYMDGTSMATPHVAATVALLKSYHPDLSVEDVRTLLQRTADPIAFSGGDAPYDPRMSDGFEYVLEELGMTLPAYYNPV
SGFGKANVYRAESMLKLNASGANAQDNSTTFKAKVTSGTTVRVYKGEKLIGRGTSKQTMAAFSIQPQKAGAVLRVVYTNG
KYETSERVVVKAGARPGQPTVNTLRSGAKSVTGRGEAGMRVVVRNSNYQLLGRGTVLPNGTFSVKTRALKKGETINVHIE
DLKGRPGKMSKTTVR
>Mature_895_residues
MKARFKQFVAMVTVLVLVLSFLPPALADSGNGMTNATLLTPGEAVEFTTGTDPVNTYWFKMERETSAMTHMEVTFESSKL
ANISVYPSADMAAKDETFDRYRASATKEEEEQTAKIEFPFAWEGPYYIKVEYMPMDLGEEIPGEEIPGDVLPVDGEEPTD
PGMPDLASDIKLVVNPVKLPVKYEQVGGDMCAVESIVQPAPERDSMLKLIRRVQSEVLGTSQKGRDLSALYYRASPYIVK
AITFDGEKRKAALTDLKTLRPLLTALVDKKAYTLKTQDAAAINRLHALVDASVPTALQGEIGEIATALEMDSLAGTPVTD
LFGKVGMTIQTDGSDAPRYIVKYKSSPNTSIGKMNAMSDVSAERIAIGKPSDYFALVDVEEASTKMQAQAKSTLESDRNV
EYIEPVQTYQSFATDVSLDYQWAINQKSVLEPFANAGIGLDKYEALNLPKRSIKVAVLDTGVDHRLLDLKGKVDVANAKN
FVDPNGEGDAIDDHGHGTHVAGVIGATRDNGVSMRGIVPNVSILPVKVLDAGGSGDTDQIALGIKYAVDAGAKVINMSLG
GNESRTLGYMLKYAYDRGVVIVAATGNDAQSRVSYPASSKYTISVGATNAFGIVSDYSNYGIGVDVVAPGSKVASLVPDG
NVVYMDGTSMATPHVAATVALLKSYHPDLSVEDVRTLLQRTADPIAFSGGDAPYDPRMSDGFEYVLEELGMTLPAYYNPV
SGFGKANVYRAESMLKLNASGANAQDNSTTFKAKVTSGTTVRVYKGEKLIGRGTSKQTMAAFSIQPQKAGAVLRVVYTNG
KYETSERVVVKAGARPGQPTVNTLRSGAKSVTGRGEAGMRVVVRNSNYQLLGRGTVLPNGTFSVKTRALKKGETINVHIE
DLKGRPGKMSKTTVR

Specific function: CWBP52 is a serine-type protease that could be involved in proteoglycan peptide bridges [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted, cell wall. Note=Released into the medium [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI31317307, Length=259, Percent_Identity=31.2741312741313, Blast_Score=84, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324576, Length=226, Percent_Identity=33.1858407079646, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320775, Length=283, Percent_Identity=29.6819787985866, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319893, Length=258, Percent_Identity=31.0077519379845, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 96151; Mature: 96151

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKARFKQFVAMVTVLVLVLSFLPPALADSGNGMTNATLLTPGEAVEFTTGTDPVNTYWFK
CCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEEECCCCEEEEECCCCCCEEEEEE
MERETSAMTHMEVTFESSKLANISVYPSADMAAKDETFDRYRASATKEEEEQTAKIEFPF
EECCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCE
AWEGPYYIKVEYMPMDLGEEIPGEEIPGDVLPVDGEEPTDPGMPDLASDIKLVVNPVKLP
EECCCEEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHCCEEEEECEECC
VKYEQVGGDMCAVESIVQPAPERDSMLKLIRRVQSEVLGTSQKGRDLSALYYRASPYIVK
EEHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEE
AITFDGEKRKAALTDLKTLRPLLTALVDKKAYTLKTQDAAAINRLHALVDASVPTALQGE
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCHHCCC
IGEIATALEMDSLAGTPVTDLFGKVGMTIQTDGSDAPRYIVKYKSSPNTSIGKMNAMSDV
HHHHHHHHHHHHCCCCCHHHHHHHCCCEEEECCCCCCEEEEEECCCCCCCCCCCCCHHCC
SAERIAIGKPSDYFALVDVEEASTKMQAQAKSTLESDRNVEYIEPVQTYQSFATDVSLDY
CCCEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHCCCCEEE
QWAINQKSVLEPFANAGIGLDKYEALNLPKRSIKVAVLDTGVDHRLLDLKGKVDVANAKN
EEECCCHHHHHHHHHCCCCCCCHHHCCCCCHHEEEEEEECCCCCEEEECCCCEEECCCCC
FVDPNGEGDAIDDHGHGTHVAGVIGATRDNGVSMRGIVPNVSILPVKVLDAGGSGDTDQI
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCEE
ALGIKYAVDAGAKVINMSLGGNESRTLGYMLKYAYDRGVVIVAATGNDAQSRVSYPASSK
EEEEEEEECCCCEEEEEECCCCCCHHHHHHHHEECCCCEEEEEECCCCHHHHCCCCCCCE
YTISVGATNAFGIVSDYSNYGIGVDVVAPGSKVASLVPDGNVVYMDGTSMATPHVAATVA
EEEEECCCCCEEEEECCCCCCCEEEEECCCCHHHEECCCCCEEEECCCCCCCCHHHHHHH
LLKSYHPDLSVEDVRTLLQRTADPIAFSGGDAPYDPRMSDGFEYVLEELGMTLPAYYNPV
HHHHCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
SGFGKANVYRAESMLKLNASGANAQDNSTTFKAKVTSGTTVRVYKGEKLIGRGTSKQTMA
CCCCCCCEEECCEEEEEECCCCCCCCCCEEEEEEECCCCEEEEEECCEEEECCCCCCEEE
AFSIQPQKAGAVLRVVYTNGKYETSERVVVKAGARPGQPTVNTLRSGAKSVTGRGEAGMR
EEEECCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHCCHHHCCCCCCCCCE
VVVRNSNYQLLGRGTVLPNGTFSVKTRALKKGETINVHIEDLKGRPGKMSKTTVR
EEEECCCEEEEECCEECCCCCEEEEEHHHCCCCEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MKARFKQFVAMVTVLVLVLSFLPPALADSGNGMTNATLLTPGEAVEFTTGTDPVNTYWFK
CCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEEECCCCEEEEECCCCCCEEEEEE
MERETSAMTHMEVTFESSKLANISVYPSADMAAKDETFDRYRASATKEEEEQTAKIEFPF
EECCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCE
AWEGPYYIKVEYMPMDLGEEIPGEEIPGDVLPVDGEEPTDPGMPDLASDIKLVVNPVKLP
EECCCEEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHCCEEEEECEECC
VKYEQVGGDMCAVESIVQPAPERDSMLKLIRRVQSEVLGTSQKGRDLSALYYRASPYIVK
EEHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEE
AITFDGEKRKAALTDLKTLRPLLTALVDKKAYTLKTQDAAAINRLHALVDASVPTALQGE
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCHHCCC
IGEIATALEMDSLAGTPVTDLFGKVGMTIQTDGSDAPRYIVKYKSSPNTSIGKMNAMSDV
HHHHHHHHHHHHCCCCCHHHHHHHCCCEEEECCCCCCEEEEEECCCCCCCCCCCCCHHCC
SAERIAIGKPSDYFALVDVEEASTKMQAQAKSTLESDRNVEYIEPVQTYQSFATDVSLDY
CCCEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHCCCCEEE
QWAINQKSVLEPFANAGIGLDKYEALNLPKRSIKVAVLDTGVDHRLLDLKGKVDVANAKN
EEECCCHHHHHHHHHCCCCCCCHHHCCCCCHHEEEEEEECCCCCEEEECCCCEEECCCCC
FVDPNGEGDAIDDHGHGTHVAGVIGATRDNGVSMRGIVPNVSILPVKVLDAGGSGDTDQI
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCEE
ALGIKYAVDAGAKVINMSLGGNESRTLGYMLKYAYDRGVVIVAATGNDAQSRVSYPASSK
EEEEEEEECCCCEEEEEECCCCCCHHHHHHHHEECCCCEEEEEECCCCHHHHCCCCCCCE
YTISVGATNAFGIVSDYSNYGIGVDVVAPGSKVASLVPDGNVVYMDGTSMATPHVAATVA
EEEEECCCCCEEEEECCCCCCCEEEEECCCCHHHEECCCCCEEEECCCCCCCCHHHHHHH
LLKSYHPDLSVEDVRTLLQRTADPIAFSGGDAPYDPRMSDGFEYVLEELGMTLPAYYNPV
HHHHCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
SGFGKANVYRAESMLKLNASGANAQDNSTTFKAKVTSGTTVRVYKGEKLIGRGTSKQTMA
CCCCCCCEEECCEEEEEECCCCCCCCCCEEEEEEECCCCEEEEEECCEEEECCCCCCEEE
AFSIQPQKAGAVLRVVYTNGKYETSERVVVKAGARPGQPTVNTLRSGAKSVTGRGEAGMR
EEEECCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHCCHHHCCCCCCCCCE
VVVRNSNYQLLGRGTVLPNGTFSVKTRALKKGETINVHIEDLKGRPGKMSKTTVR
EEEECCCEEEEECCEECCCCCEEEEEHHHCCCCEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9004506; 9353931; 9384377; 10658653 [H]