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The map label for this gene is treA [H]

Identifier: 229916666

GI number: 229916666

Start: 885881

End: 887515

Strand: Reverse

Name: treA [H]

Synonym: EAT1b_0938

Alternate gene names: 229916666

Gene position: 887515-885881 (Counterclockwise)

Preceding gene: 229916667

Following gene: 229916665

Centisome position: 29.58

GC content: 53.03

Gene sequence:

>1635_bases
ATGACACAGAAAAATTGGCGCAAATCAGTCGTCTATCAAATTTACCCGAAAAGCTTTTACAGTCCGGAAGGGAATGCGAC
CGGATCGATCAAAGGGGTGACGGCGAAGCTGGATTACTTGGCAGAACTCGGCATCGAATACATTTGGATGACGCCTGTCT
ATCAGTCACCTCAACACGATAACGGCTATGACGTGAGTGATTACTATGCCATCGACCCGTCTTACGGGACGATGGAAGAC
CTCGATGAATTGATCCGTGAAGCAGAGGCGCGGGGCATCGGCCTCATGATGGACATCGTCGTCAACCACTCATCGACCGA
ACACGAATGGTTCCAAAAATCATTGGCGGGAGACGAGCGGTACCGTGACTACTACATCTGGCGCGACGAACCGACGAACT
GGGAGTCGAAGTTCGGCGGAAACGCGTGGGAATATGATGAGAAGAGCGGGCAATATTATCTCCACTTGTTCGACGTGACC
CAGGCCGACTTGAACTGGGAGAATGAACAGATGCGCGAGGACGTCTACGAGATGATGCGGTTCTGGCGTAAGAAAGGAAT
CAAAGGATTCCGTCTCGACGTCATCAACCTCATCTCGAAAGAACAGGACTTCCCAGAAGACACGTCGGACGGGCGCAAAT
TCTATACGGACGGTCCACGCATCCACGAATATTTAAAAGAGATGAACCGAGAAGTATTCGACGGGCATGACGTCATCACG
GTCGGAGAGATGTCTTCGACGACGCTCGACCACTGCGTCCGCTATTCAAACCCGGACGAGAACGAGCTCAGCATGACGTT
CAGCTTCCATCACTTGAAAGTCGACTACCCGAACGGAGAGAAGTTCGTCGCTGCACCGTTCGATTTCATTCAATTGAAAG
ACATCATGTCAACGTGGCAACGCGGGATGCACGGGAAAGGATGGAACGCCATCTTCTGGTGCAATCACGACCAACCGCGT
GTCGTCAGCCGTTTCGGGAATGACACGAACCATCGCGTCGAGAGCGCGAAGATGCTCGCGACAGTGCTCCATGGCCTTCA
AGGGACACCGTATATCTATCAAGGGGAAGAAATCGGGATGACGAATCCTGGCTTCGACTCGCTCGATGAATATCGGGATA
TCGAGACGCTCAATATCTACAAGTTGAAGCGGGAAGAGGGCGTGTCGCACGAAGACATGATGGCCGCCATCAAACAGAAG
TCACGCGACAACTCGCGGACGCCGATGCAGTGGGATGCGACGACGCATGCCGGCTTCACGAGCGGCACGCCTTGGATCAA
CGTGGCACCGAACTATGAGGACGTGAACGTCGAGACGGCGCTCCGTGACCCGAACTCGGTGTTCTACCACTACAAACACT
TGATTGCATTACGAAAAGAACTTGACGTCTTGACGGATGGGGACTACACGCTTCTCACGCCTGATTCGTTGGATGTTTGG
GCATATACACGGAAGACCGACCGCGAGGAACTTCTCGTCGTCGCCAACTTCTATGGAACCGAAACGACGTACACGATTCC
GGAAGGGTTCGAGCGGGTGAACGTCGTCAGCCACAACTATGACGTGCCTGAGCTCGACGGGATGACGTTATCCCTTCGTC
CGTACGAGGCGATCATGTTCTACAAACAGAAATAA

Upstream 100 bases:

>100_bases
AGAAAACAAAGTCGCATAAGTAATGACTCGGGAGGGAGGGACGGCAGTTCTTCCCTCTTACTTATTGAAATGAAAACTCT
TACAAAAGGAGATGTCGTTG

Downstream 100 bases:

>100_bases
CAGGTGGGACCCGACGCTTTCGTCGGGTCCTATTTGTGTAGTCGACCTATGCTGTTTTAGATAAGTCGAATCGCATTTAT
ATAGCCGTTTTGGTAGCGTG

Product: alpha,alpha-phosphotrehalase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MTQKNWRKSVVYQIYPKSFYSPEGNATGSIKGVTAKLDYLAELGIEYIWMTPVYQSPQHDNGYDVSDYYAIDPSYGTMED
LDELIREAEARGIGLMMDIVVNHSSTEHEWFQKSLAGDERYRDYYIWRDEPTNWESKFGGNAWEYDEKSGQYYLHLFDVT
QADLNWENEQMREDVYEMMRFWRKKGIKGFRLDVINLISKEQDFPEDTSDGRKFYTDGPRIHEYLKEMNREVFDGHDVIT
VGEMSSTTLDHCVRYSNPDENELSMTFSFHHLKVDYPNGEKFVAAPFDFIQLKDIMSTWQRGMHGKGWNAIFWCNHDQPR
VVSRFGNDTNHRVESAKMLATVLHGLQGTPYIYQGEEIGMTNPGFDSLDEYRDIETLNIYKLKREEGVSHEDMMAAIKQK
SRDNSRTPMQWDATTHAGFTSGTPWINVAPNYEDVNVETALRDPNSVFYHYKHLIALRKELDVLTDGDYTLLTPDSLDVW
AYTRKTDREELLVVANFYGTETTYTIPEGFERVNVVSHNYDVPELDGMTLSLRPYEAIMFYKQK

Sequences:

>Translated_544_residues
MTQKNWRKSVVYQIYPKSFYSPEGNATGSIKGVTAKLDYLAELGIEYIWMTPVYQSPQHDNGYDVSDYYAIDPSYGTMED
LDELIREAEARGIGLMMDIVVNHSSTEHEWFQKSLAGDERYRDYYIWRDEPTNWESKFGGNAWEYDEKSGQYYLHLFDVT
QADLNWENEQMREDVYEMMRFWRKKGIKGFRLDVINLISKEQDFPEDTSDGRKFYTDGPRIHEYLKEMNREVFDGHDVIT
VGEMSSTTLDHCVRYSNPDENELSMTFSFHHLKVDYPNGEKFVAAPFDFIQLKDIMSTWQRGMHGKGWNAIFWCNHDQPR
VVSRFGNDTNHRVESAKMLATVLHGLQGTPYIYQGEEIGMTNPGFDSLDEYRDIETLNIYKLKREEGVSHEDMMAAIKQK
SRDNSRTPMQWDATTHAGFTSGTPWINVAPNYEDVNVETALRDPNSVFYHYKHLIALRKELDVLTDGDYTLLTPDSLDVW
AYTRKTDREELLVVANFYGTETTYTIPEGFERVNVVSHNYDVPELDGMTLSLRPYEAIMFYKQK
>Mature_543_residues
TQKNWRKSVVYQIYPKSFYSPEGNATGSIKGVTAKLDYLAELGIEYIWMTPVYQSPQHDNGYDVSDYYAIDPSYGTMEDL
DELIREAEARGIGLMMDIVVNHSSTEHEWFQKSLAGDERYRDYYIWRDEPTNWESKFGGNAWEYDEKSGQYYLHLFDVTQ
ADLNWENEQMREDVYEMMRFWRKKGIKGFRLDVINLISKEQDFPEDTSDGRKFYTDGPRIHEYLKEMNREVFDGHDVITV
GEMSSTTLDHCVRYSNPDENELSMTFSFHHLKVDYPNGEKFVAAPFDFIQLKDIMSTWQRGMHGKGWNAIFWCNHDQPRV
VSRFGNDTNHRVESAKMLATVLHGLQGTPYIYQGEEIGMTNPGFDSLDEYRDIETLNIYKLKREEGVSHEDMMAAIKQKS
RDNSRTPMQWDATTHAGFTSGTPWINVAPNYEDVNVETALRDPNSVFYHYKHLIALRKELDVLTDGDYTLLTPDSLDVWA
YTRKTDREELLVVANFYGTETTYTIPEGFERVNVVSHNYDVPELDGMTLSLRPYEAIMFYKQK

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=526, Percent_Identity=29.467680608365, Blast_Score=226, Evalue=3e-59,
Organism=Escherichia coli, GI1790687, Length=544, Percent_Identity=53.3088235294118, Blast_Score=621, Evalue=1e-179,
Organism=Escherichia coli, GI1786604, Length=211, Percent_Identity=25.5924170616114, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI25147709, Length=492, Percent_Identity=22.5609756097561, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI32565753, Length=365, Percent_Identity=23.8356164383562, Blast_Score=86, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6322245, Length=573, Percent_Identity=37.17277486911, Blast_Score=370, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6321726, Length=574, Percent_Identity=36.9337979094077, Blast_Score=362, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6324416, Length=574, Percent_Identity=36.2369337979094, Blast_Score=348, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6322241, Length=576, Percent_Identity=36.4583333333333, Blast_Score=347, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6322021, Length=576, Percent_Identity=36.4583333333333, Blast_Score=347, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6321731, Length=574, Percent_Identity=34.8432055749129, Blast_Score=328, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6319776, Length=574, Percent_Identity=34.6689895470383, Blast_Score=327, Evalue=3e-90,
Organism=Drosophila melanogaster, GI24586599, Length=584, Percent_Identity=31.1643835616438, Blast_Score=269, Evalue=4e-72,
Organism=Drosophila melanogaster, GI45549022, Length=559, Percent_Identity=33.4525939177102, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI221330053, Length=493, Percent_Identity=34.2799188640974, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24583747, Length=535, Percent_Identity=34.018691588785, Blast_Score=261, Evalue=8e-70,
Organism=Drosophila melanogaster, GI24583749, Length=535, Percent_Identity=34.018691588785, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24583745, Length=551, Percent_Identity=33.7568058076225, Blast_Score=259, Evalue=4e-69,
Organism=Drosophila melanogaster, GI24586593, Length=558, Percent_Identity=32.258064516129, Blast_Score=252, Evalue=4e-67,
Organism=Drosophila melanogaster, GI24586591, Length=498, Percent_Identity=34.7389558232932, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24586587, Length=579, Percent_Identity=30.9153713298791, Blast_Score=249, Evalue=4e-66,
Organism=Drosophila melanogaster, GI24586597, Length=542, Percent_Identity=32.6568265682657, Blast_Score=248, Evalue=9e-66,
Organism=Drosophila melanogaster, GI24586589, Length=515, Percent_Identity=33.0097087378641, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI281360393, Length=502, Percent_Identity=31.2749003984064, Blast_Score=199, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 63549; Mature: 63418

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKNWRKSVVYQIYPKSFYSPEGNATGSIKGVTAKLDYLAELGIEYIWMTPVYQSPQHD
CCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCEEEEECCCCCCCCCC
NGYDVSDYYAIDPSYGTMEDLDELIREAEARGIGLMMDIVVNHSSTEHEWFQKSLAGDER
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHCCCCC
YRDYYIWRDEPTNWESKFGGNAWEYDEKSGQYYLHLFDVTQADLNWENEQMREDVYEMMR
CCCEEEECCCCCCHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHH
FWRKKGIKGFRLDVINLISKEQDFPEDTSDGRKFYTDGPRIHEYLKEMNREVFDGHDVIT
HHHHCCCCEEHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCEEE
VGEMSSTTLDHCVRYSNPDENELSMTFSFHHLKVDYPNGEKFVAAPFDFIQLKDIMSTWQ
ECCCCHHHHHHHHHCCCCCCCCEEEEEEEEEEEEECCCCCEEEECCHHHHHHHHHHHHHH
RGMHGKGWNAIFWCNHDQPRVVSRFGNDTNHRVESAKMLATVLHGLQGTPYIYQGEEIGM
HCCCCCCCCEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCC
TNPGFDSLDEYRDIETLNIYKLKREEGVSHEDMMAAIKQKSRDNSRTPMQWDATTHAGFT
CCCCCCCHHHHCCCCEEEEEEEHHHHCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCCCC
SGTPWINVAPNYEDVNVETALRDPNSVFYHYKHLIALRKELDVLTDGDYTLLTPDSLDVW
CCCCEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCEEECCCEEEECCCCCEEE
AYTRKTDREELLVVANFYGTETTYTIPEGFERVNVVSHNYDVPELDGMTLSLRPYEAIMF
EEECCCCCCCEEEEEEECCCCEEEECCCCCCEEEEEECCCCCCCCCCCEEEECCCEEEEE
YKQK
EECC
>Mature Secondary Structure 
TQKNWRKSVVYQIYPKSFYSPEGNATGSIKGVTAKLDYLAELGIEYIWMTPVYQSPQHD
CCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCEEEEECCCCCCCCCC
NGYDVSDYYAIDPSYGTMEDLDELIREAEARGIGLMMDIVVNHSSTEHEWFQKSLAGDER
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHCCCCC
YRDYYIWRDEPTNWESKFGGNAWEYDEKSGQYYLHLFDVTQADLNWENEQMREDVYEMMR
CCCEEEECCCCCCHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHH
FWRKKGIKGFRLDVINLISKEQDFPEDTSDGRKFYTDGPRIHEYLKEMNREVFDGHDVIT
HHHHCCCCEEHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCEEE
VGEMSSTTLDHCVRYSNPDENELSMTFSFHHLKVDYPNGEKFVAAPFDFIQLKDIMSTWQ
ECCCCHHHHHHHHHCCCCCCCCEEEEEEEEEEEEECCCCCEEEECCHHHHHHHHHHHHHH
RGMHGKGWNAIFWCNHDQPRVVSRFGNDTNHRVESAKMLATVLHGLQGTPYIYQGEEIGM
HCCCCCCCCEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCC
TNPGFDSLDEYRDIETLNIYKLKREEGVSHEDMMAAIKQKSRDNSRTPMQWDATTHAGFT
CCCCCCCHHHHCCCCEEEEEEEHHHHCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCCCC
SGTPWINVAPNYEDVNVETALRDPNSVFYHYKHLIALRKELDVLTDGDYTLLTPDSLDVW
CCCCEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCEEECCCEEEECCCCCEEE
AYTRKTDREELLVVANFYGTETTYTIPEGFERVNVVSHNYDVPELDGMTLSLRPYEAIMF
EEECCCCCCCEEEEEEECCCCEEEECCCCCCEEEEEECCCCCCCCCCCEEEECCCEEEEE
YKQK
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7651129; 8969503; 9384377; 7751281 [H]