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The map label for this gene is hprK

Identifier: 229916609

GI number: 229916609

Start: 832414

End: 833349

Strand: Reverse

Name: hprK

Synonym: EAT1b_0881

Alternate gene names: 229916609

Gene position: 833349-832414 (Counterclockwise)

Preceding gene: 229916611

Following gene: 229916608

Centisome position: 27.78

GC content: 54.38

Gene sequence:

>936_bases
ATGCAAAATATCGTACGTACCGCTCAAGTCGTTGAGCGTTTTAAACTTCAAGTCATTGCGGGAGAGGAAGGACTTCATCG
TCCGGTCGCCACACCCGATCTGAGTCGACCGGGTCTCGTCCTTGCCGGCTATTATACGCACTATGCCAAAAACCGCTTGC
AAGTGCTTGGGAAGACGGAGTTGACATTCTACGCGAGCCTCTCGGAAGAGAAGCGTCGTGAGCGCGCTAAAATCTTGTGT
ACGGAACAGACGCCAGGAATTTTAATCACGCGTGGCTTTGATATTCCGAAAGAAATCGAGGAAGAAGCGGAAGCGGCAAA
CGTCCCGCTCATGCGGACGAATGCGGTGACGACCTCAATCGAATCACAAATCACGAACTTCCTAGAGATGGAACTCGCAC
CGATGACGGCGATGCACGGCGTGCTCGTCGACATTTACGGTGTCGGTGTCCTCATCAAGGGTCAGAGCGGGGTCGGGAAA
TCGGAGACGGCACTTGAACTCGTCAAACGAGGTCACCGCCTCGTCGCGGATGATTCGGTCGAGATTCGTCAAACGGGGGA
CCAGCTCCTCGTCGGATCGGCACCGAAGCTCATTCGTCACCTGCTCGAGATTCGTGGGATCGGCATCATCGACGTCATGA
CGTTGTTCGGTGCGGGGGCGGTGCGGTCGCATAAAAAGATCAGCCTCATCGTCAACTTGGAGAACTGGGACGCGGGCAAG
GTATACGACCGTGTCGGACTCGACCACAATACGATGAAAATCATCGACAGTGAAGTCCCGCTCTTGACAATCCCCGTTCG
ACCTGGTCGAAACTTGGCGGTCATCATCGAGGTCGCGGCGATGAACTATCGTCTACAGAACATGGGAATCAATACGGCTG
AAGAGTTCGCGGAACGTCTCGCGAACGCCATTCAGGATACTGAAGGAGACTTGTGA

Upstream 100 bases:

>100_bases
GGATGGTTTCAACAATTTTTTGACACGTTCTTCATCACTTCCCTAACCCGTCCAAGAAAGAGCTATGATACAATAATGAG
CGTGAAAGGGGCAGATACTG

Downstream 100 bases:

>100_bases
GCATGGTAGAACCGACATTTGATCGTGTGGCGTTTGAGATTGGCTCTCTGCCAATCTATTGGTATGGCATGATTATCGCC
TTCGGGGCGATGCTTGGCCT

Product: HPr kinase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MQNIVRTAQVVERFKLQVIAGEEGLHRPVATPDLSRPGLVLAGYYTHYAKNRLQVLGKTELTFYASLSEEKRRERAKILC
TEQTPGILITRGFDIPKEIEEEAEAANVPLMRTNAVTTSIESQITNFLEMELAPMTAMHGVLVDIYGVGVLIKGQSGVGK
SETALELVKRGHRLVADDSVEIRQTGDQLLVGSAPKLIRHLLEIRGIGIIDVMTLFGAGAVRSHKKISLIVNLENWDAGK
VYDRVGLDHNTMKIIDSEVPLLTIPVRPGRNLAVIIEVAAMNYRLQNMGINTAEEFAERLANAIQDTEGDL

Sequences:

>Translated_311_residues
MQNIVRTAQVVERFKLQVIAGEEGLHRPVATPDLSRPGLVLAGYYTHYAKNRLQVLGKTELTFYASLSEEKRRERAKILC
TEQTPGILITRGFDIPKEIEEEAEAANVPLMRTNAVTTSIESQITNFLEMELAPMTAMHGVLVDIYGVGVLIKGQSGVGK
SETALELVKRGHRLVADDSVEIRQTGDQLLVGSAPKLIRHLLEIRGIGIIDVMTLFGAGAVRSHKKISLIVNLENWDAGK
VYDRVGLDHNTMKIIDSEVPLLTIPVRPGRNLAVIIEVAAMNYRLQNMGINTAEEFAERLANAIQDTEGDL
>Mature_311_residues
MQNIVRTAQVVERFKLQVIAGEEGLHRPVATPDLSRPGLVLAGYYTHYAKNRLQVLGKTELTFYASLSEEKRRERAKILC
TEQTPGILITRGFDIPKEIEEEAEAANVPLMRTNAVTTSIESQITNFLEMELAPMTAMHGVLVDIYGVGVLIKGQSGVGK
SETALELVKRGHRLVADDSVEIRQTGDQLLVGSAPKLIRHLLEIRGIGIIDVMTLFGAGAVRSHKKISLIVNLENWDAGK
VYDRVGLDHNTMKIIDSEVPLLTIPVRPGRNLAVIIEVAAMNYRLQNMGINTAEEFAERLANAIQDTEGDL

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPRK_EXISA (C4L5J5)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002885255.1
- GeneID:   7869047
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_0881
- OMA:   IHGVLVD
- ProtClustDB:   CLSK2489814
- HAMAP:   MF_01249
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126
- TIGRFAMs:   TIGR00679

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N

EC number: NA

Molecular weight: Translated: 34299; Mature: 34299

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: ACT_SITE 139-139 ACT_SITE 160-160 ACT_SITE 178-178 ACT_SITE 244-244

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNIVRTAQVVERFKLQVIAGEEGLHRPVATPDLSRPGLVLAGYYTHYAKNRLQVLGKTE
CCHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHEECCCE
LTFYASLSEEKRRERAKILCTEQTPGILITRGFDIPKEIEEEAEAANVPLMRTNAVTTSI
EEEEECCHHHHHHHHHEEEEECCCCCEEEEECCCCHHHHHHHHHHCCCCEEECCHHHHHH
ESQITNFLEMELAPMTAMHGVLVDIYGVGVLIKGQSGVGKSETALELVKRGHRLVADDSV
HHHHHHHHHHHHHHHHHHHHHHHEEEECEEEEECCCCCCCHHHHHHHHHCCCEEECCCCC
EIRQTGDQLLVGSAPKLIRHLLEIRGIGIIDVMTLFGAGAVRSHKKISLIVNLENWDAGK
CEECCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCC
VYDRVGLDHNTMKIIDSEVPLLTIPVRPGRNLAVIIEVAAMNYRLQNMGINTAEEFAERL
HHHHHCCCCCHHEEECCCCCEEEEECCCCCCEEEEEEEEECCEEHHHCCCCHHHHHHHHH
ANAIQDTEGDL
HHHHHCCCCCC
>Mature Secondary Structure
MQNIVRTAQVVERFKLQVIAGEEGLHRPVATPDLSRPGLVLAGYYTHYAKNRLQVLGKTE
CCHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHEECCCE
LTFYASLSEEKRRERAKILCTEQTPGILITRGFDIPKEIEEEAEAANVPLMRTNAVTTSI
EEEEECCHHHHHHHHHEEEEECCCCCEEEEECCCCHHHHHHHHHHCCCCEEECCHHHHHH
ESQITNFLEMELAPMTAMHGVLVDIYGVGVLIKGQSGVGKSETALELVKRGHRLVADDSV
HHHHHHHHHHHHHHHHHHHHHHHEEEECEEEEECCCCCCCHHHHHHHHHCCCEEECCCCC
EIRQTGDQLLVGSAPKLIRHLLEIRGIGIIDVMTLFGAGAVRSHKKISLIVNLENWDAGK
CEECCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCC
VYDRVGLDHNTMKIIDSEVPLLTIPVRPGRNLAVIIEVAAMNYRLQNMGINTAEEFAERL
HHHHHCCCCCHHEEECCCCCEEEEECCCCCCEEEEEEEEECCEEHHHCCCCHHHHHHHHH
ANAIQDTEGDL
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA