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The map label for this gene is trxB [H]

Identifier: 229916604

GI number: 229916604

Start: 827679

End: 828632

Strand: Reverse

Name: trxB [H]

Synonym: EAT1b_0876

Alternate gene names: 229916604

Gene position: 828632-827679 (Counterclockwise)

Preceding gene: 229916605

Following gene: 229916603

Centisome position: 27.62

GC content: 51.05

Gene sequence:

>954_bases
ATGACAGAAGAAAAAATTTATGACGTCATTATCATCGGTGCCGGTCCTGCCGGAATGACCGCTGCGCTATATGCTTCACG
TGCGAACCTTTCAACACTTATGATCGAACGCGGGATTCCGGGTGGTCAGATGGCCAACACGGAAGACATCGAGAACTATC
CGGGCTATGACAGCATCCTGGGTCCTGACTTGTCTCAGAAGATGTTCGACCATTCGAAAGCGTTCGGAGCGGAGTATGCA
TATGGGGACGTGCAACGCATCTCGGATGAAACAGAGTATAAAATCGTCCATGCGCACAACCGTGACTATAAAGCACGTGC
GATCATCCTCGCCTCTGGTGCTCAGTATAAGAAAATCGGTGTACCGGGTGAAGAAGAACTCGGCGGCCGTGGCGTATCGT
ACTGTGCGGTATGTGACGGGGCATTCTTCAAAGGGAAAGATTTATTCGTCATCGGTGGTGGCGACTCAGCCGTTGAAGAA
GGTGTCTTCTTGACACGTTTCGCGAACAAGGTGACGATCGTTCACCGTCGCGATGAGCTCCGCGCGCAAAAGATTCTTCA
AAAACGTGCGTTCGACAATGAGAAAATCGATTTCATTTGGAACCACACATTGAAAGAAATCACAGAGAAAGACGGGAAAG
TCGGTGGGGCTCGTCTCGTCAGCACAATTGACGGGACTGAGACAGACCACGAGATTGACGGCGTCTTCATCTATATCGGC
ATGAACCCGATTACAGGGTTCGTCCAAGACCTCGGTATCACGAACGAGCAAGGCTACATCGTCACAAACGAGGCGATGGA
AACGAACATCCCAGGGATTTTCGCTGCCGGCGACGTTCGCGAGAAAACGCTTCGTCAAGTCGTCACAGCGACGAACGACG
GATCGATTGCCGCTCAGAATGCTCAACATTTCATCGAGGGACTCCTCGAATCGTTGCAAGAACAAAACGCATGA

Upstream 100 bases:

>100_bases
GTTCGTTCAAACGGACACTCGAACAAGCATAAAGATAGACGATACCCTTATAGGTTTCTTATACTAAAGGCAATCAATTT
CTTGCAGAGGTGGAATCAAC

Downstream 100 bases:

>100_bases
TTCAAGAAGGTAGGACTGCGGGGAACCGCGGTCCTTCTCTTTTTTTCGGACGTTCGTTATACTAGATGGAGAGAGCTACA
CACACGGCTCGGTTGTCAAT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR; General stress protein 35; GSP35 [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTEEKIYDVIIIGAGPAGMTAALYASRANLSTLMIERGIPGGQMANTEDIENYPGYDSILGPDLSQKMFDHSKAFGAEYA
YGDVQRISDETEYKIVHAHNRDYKARAIILASGAQYKKIGVPGEEELGGRGVSYCAVCDGAFFKGKDLFVIGGGDSAVEE
GVFLTRFANKVTIVHRRDELRAQKILQKRAFDNEKIDFIWNHTLKEITEKDGKVGGARLVSTIDGTETDHEIDGVFIYIG
MNPITGFVQDLGITNEQGYIVTNEAMETNIPGIFAAGDVREKTLRQVVTATNDGSIAAQNAQHFIEGLLESLQEQNA

Sequences:

>Translated_317_residues
MTEEKIYDVIIIGAGPAGMTAALYASRANLSTLMIERGIPGGQMANTEDIENYPGYDSILGPDLSQKMFDHSKAFGAEYA
YGDVQRISDETEYKIVHAHNRDYKARAIILASGAQYKKIGVPGEEELGGRGVSYCAVCDGAFFKGKDLFVIGGGDSAVEE
GVFLTRFANKVTIVHRRDELRAQKILQKRAFDNEKIDFIWNHTLKEITEKDGKVGGARLVSTIDGTETDHEIDGVFIYIG
MNPITGFVQDLGITNEQGYIVTNEAMETNIPGIFAAGDVREKTLRQVVTATNDGSIAAQNAQHFIEGLLESLQEQNA
>Mature_316_residues
TEEKIYDVIIIGAGPAGMTAALYASRANLSTLMIERGIPGGQMANTEDIENYPGYDSILGPDLSQKMFDHSKAFGAEYAY
GDVQRISDETEYKIVHAHNRDYKARAIILASGAQYKKIGVPGEEELGGRGVSYCAVCDGAFFKGKDLFVIGGGDSAVEEG
VFLTRFANKVTIVHRRDELRAQKILQKRAFDNEKIDFIWNHTLKEITEKDGKVGGARLVSTIDGTETDHEIDGVFIYIGM
NPITGFVQDLGITNEQGYIVTNEAMETNIPGIFAAGDVREKTLRQVVTATNDGSIAAQNAQHFIEGLLESLQEQNA

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI65787454, Length=328, Percent_Identity=25, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI21389617, Length=328, Percent_Identity=25, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226437568, Length=328, Percent_Identity=25, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1787114, Length=321, Percent_Identity=37.6947040498442, Blast_Score=219, Evalue=1e-58,
Organism=Escherichia coli, GI87081763, Length=312, Percent_Identity=35.2564102564103, Blast_Score=156, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=41.7197452229299, Blast_Score=215, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6321898, Length=315, Percent_Identity=40.6349206349206, Blast_Score=202, Evalue=5e-53,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34653; Mature: 34522

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEEKIYDVIIIGAGPAGMTAALYASRANLSTLMIERGIPGGQMANTEDIENYPGYDSIL
CCCCCEEEEEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
GPDLSQKMFDHSKAFGAEYAYGDVQRISDETEYKIVHAHNRDYKARAIILASGAQYKKIG
CCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEEECCCCCEEEEEEEECCCCEEECC
VPGEEELGGRGVSYCAVCDGAFFKGKDLFVIGGGDSAVEEGVFLTRFANKVTIVHRRDEL
CCCCHHHCCCCCEEEEEECCCEECCCEEEEEECCCHHHHCCEEEEECCCEEEEEECHHHH
RAQKILQKRAFDNEKIDFIWNHTLKEITEKDGKVGGARLVSTIDGTETDHEIDGVFIYIG
HHHHHHHHHCCCCCCEEEEEHHHHHHHHHHCCCCCCHHEEEECCCCCCCCCCCEEEEEEE
MNPITGFVQDLGITNEQGYIVTNEAMETNIPGIFAAGDVREKTLRQVVTATNDGSIAAQN
CCHHHHHHHHCCCCCCCCEEEECCCHHCCCCCEEECCCHHHHHHHHHHHCCCCCCEEHHH
AQHFIEGLLESLQEQNA
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEEKIYDVIIIGAGPAGMTAALYASRANLSTLMIERGIPGGQMANTEDIENYPGYDSIL
CCCCEEEEEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
GPDLSQKMFDHSKAFGAEYAYGDVQRISDETEYKIVHAHNRDYKARAIILASGAQYKKIG
CCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEEECCCCCEEEEEEEECCCCEEECC
VPGEEELGGRGVSYCAVCDGAFFKGKDLFVIGGGDSAVEEGVFLTRFANKVTIVHRRDEL
CCCCHHHCCCCCEEEEEECCCEECCCEEEEEECCCHHHHCCEEEEECCCEEEEEECHHHH
RAQKILQKRAFDNEKIDFIWNHTLKEITEKDGKVGGARLVSTIDGTETDHEIDGVFIYIG
HHHHHHHHHCCCCCCEEEEEHHHHHHHHHHCCCCCCHHEEEECCCCCCCCCCCEEEEEEE
MNPITGFVQDLGITNEQGYIVTNEAMETNIPGIFAAGDVREKTLRQVVTATNDGSIAAQN
CCHHHHHHHHCCCCCCCCEEEECCCHHCCCCCEEECCCHHHHHHHHHHHCCCCCCEEHHH
AQHFIEGLLESLQEQNA
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]