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The map label for this gene is gapA1 [H]

Identifier: 229916592

GI number: 229916592

Start: 817910

End: 818917

Strand: Reverse

Name: gapA1 [H]

Synonym: EAT1b_0864

Alternate gene names: 229916592

Gene position: 818917-817910 (Counterclockwise)

Preceding gene: 229916593

Following gene: 229916591

Centisome position: 27.3

GC content: 46.83

Gene sequence:

>1008_bases
ATGGCAGTAAAAGTTGGTATTAACGGATTTGGACGTATCGGTCGTTTAGCATTCCGCGAGATCATCAAAAACGAAGGAAT
CGAAGTTGTTGCAATCAACGACTTGACAGACACGAAGATGCTTGCGCACCTTCTCAAGTATGACACGACTCAAGGTCGTT
TCGACGGAGAAGTTGAAGTACACGACGATCACTTCCTCGTAAACGGAGAGAAAGTTATCACGCTTGCTAACCGTAACCCT
GAAGAACTTCCATGGGGAGACCTCGGTGTAGACATCGTTCTCGAATGTACTGGATTCTTCACTTCAAAAGAAAAAGCTGA
GCTTCACTTGAAAGCTGGCGCGAAGAAAGTTGTTATCTCGGCTCCTGCTACAGGTGACATGAAAACTGTTGTTTACAACA
CAAACCACGACATCCTCGATGGTACTGAAACAGTTATCTCAGGTGCTTCTTGTACAACAAACTGCTTGGCGCCAATGGCT
AAAGTACTTCAAGACCAGTTCGGAATCGTTGAAGGTCTCATGACGACAATCCACGCTTACACTGGCGACCAAAACACGCT
TGACGCTCCGCACCCGAAAGGTGACTTCCGTCGTGCGCGTGCGGCTGCAGCGAACATCGTTCCTAACACAACAGGTGCTG
CGAAAGCAATCGGTCTCGTAATCCCTGAACTTCAAGGAAAACTTGACGGTGCTGCACAACGTGTACCAGTTGCTACAGGT
TCACTCACTGAGCTCGTAACTGTACTCGACAAGCAAGTATCTGTTGACGAAGTAAACGCAGCAATGAAAGCAGCAGCGAA
CGAGTCATTCGGTTACACTGAAGACGAAATCGTTTCTTCTGACATCGTTGGAATCACATACGGTTCACTCTTCGACGCAA
CTCAAACGAAAGTCATGACAGTTGGCGACAAGCAACTCGTTAAAACAGTTTCTTGGTACGACAACGAAATGTCTTACACT
GCACAATTGGTTCGCACAGTTAAGCACTTCGCTAACATCGCGAAGTAA

Upstream 100 bases:

>100_bases
CAGACGAAGGTGCGGCGAAAGAATTATTAACTTGTTATTAAAGAGTTGACCCCCCGTTGGCTCTTCAATAAATAGCTTCT
ACCCTAAGGAGGAAATTAAC

Downstream 100 bases:

>100_bases
TTTCGTGAACTAAATAGAATCAAATAGGAGCGGAAACAAGAGATTGTTCTCCGCTCTATTTATGAAATGACACGCACGAC
ATATGGAGGCGAAAGTTATG

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH 1 [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAVKVGINGFGRIGRLAFREIIKNEGIEVVAINDLTDTKMLAHLLKYDTTQGRFDGEVEVHDDHFLVNGEKVITLANRNP
EELPWGDLGVDIVLECTGFFTSKEKAELHLKAGAKKVVISAPATGDMKTVVYNTNHDILDGTETVISGASCTTNCLAPMA
KVLQDQFGIVEGLMTTIHAYTGDQNTLDAPHPKGDFRRARAAAANIVPNTTGAAKAIGLVIPELQGKLDGAAQRVPVATG
SLTELVTVLDKQVSVDEVNAAMKAAANESFGYTEDEIVSSDIVGITYGSLFDATQTKVMTVGDKQLVKTVSWYDNEMSYT
AQLVRTVKHFANIAK

Sequences:

>Translated_335_residues
MAVKVGINGFGRIGRLAFREIIKNEGIEVVAINDLTDTKMLAHLLKYDTTQGRFDGEVEVHDDHFLVNGEKVITLANRNP
EELPWGDLGVDIVLECTGFFTSKEKAELHLKAGAKKVVISAPATGDMKTVVYNTNHDILDGTETVISGASCTTNCLAPMA
KVLQDQFGIVEGLMTTIHAYTGDQNTLDAPHPKGDFRRARAAAANIVPNTTGAAKAIGLVIPELQGKLDGAAQRVPVATG
SLTELVTVLDKQVSVDEVNAAMKAAANESFGYTEDEIVSSDIVGITYGSLFDATQTKVMTVGDKQLVKTVSWYDNEMSYT
AQLVRTVKHFANIAK
>Mature_334_residues
AVKVGINGFGRIGRLAFREIIKNEGIEVVAINDLTDTKMLAHLLKYDTTQGRFDGEVEVHDDHFLVNGEKVITLANRNPE
ELPWGDLGVDIVLECTGFFTSKEKAELHLKAGAKKVVISAPATGDMKTVVYNTNHDILDGTETVISGASCTTNCLAPMAK
VLQDQFGIVEGLMTTIHAYTGDQNTLDAPHPKGDFRRARAAAANIVPNTTGAAKAIGLVIPELQGKLDGAAQRVPVATGS
LTELVTVLDKQVSVDEVNAAMKAAANESFGYTEDEIVSSDIVGITYGSLFDATQTKVMTVGDKQLVKTVSWYDNEMSYTA
QLVRTVKHFANIAK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=335, Percent_Identity=45.3731343283582, Blast_Score=295, Evalue=6e-80,
Organism=Homo sapiens, GI7657116, Length=331, Percent_Identity=43.202416918429, Blast_Score=276, Evalue=3e-74,
Organism=Escherichia coli, GI1788079, Length=335, Percent_Identity=49.5522388059701, Blast_Score=325, Evalue=2e-90,
Organism=Escherichia coli, GI1789295, Length=342, Percent_Identity=41.2280701754386, Blast_Score=258, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI32566163, Length=341, Percent_Identity=46.9208211143695, Blast_Score=293, Evalue=1e-79,
Organism=Caenorhabditis elegans, GI17568413, Length=341, Percent_Identity=46.9208211143695, Blast_Score=293, Evalue=1e-79,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=45.2662721893491, Blast_Score=285, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=45.5621301775148, Blast_Score=284, Evalue=4e-77,
Organism=Saccharomyces cerevisiae, GI6322409, Length=335, Percent_Identity=45.9701492537313, Blast_Score=305, Evalue=5e-84,
Organism=Saccharomyces cerevisiae, GI6321631, Length=334, Percent_Identity=47.0059880239521, Blast_Score=303, Evalue=3e-83,
Organism=Saccharomyces cerevisiae, GI6322468, Length=334, Percent_Identity=46.7065868263473, Blast_Score=302, Evalue=6e-83,
Organism=Drosophila melanogaster, GI17933600, Length=331, Percent_Identity=46.8277945619335, Blast_Score=289, Evalue=2e-78,
Organism=Drosophila melanogaster, GI18110149, Length=331, Percent_Identity=46.8277945619335, Blast_Score=289, Evalue=2e-78,
Organism=Drosophila melanogaster, GI85725000, Length=331, Percent_Identity=46.2235649546828, Blast_Score=284, Evalue=7e-77,
Organism=Drosophila melanogaster, GI22023983, Length=331, Percent_Identity=46.2235649546828, Blast_Score=284, Evalue=7e-77,
Organism=Drosophila melanogaster, GI19922412, Length=328, Percent_Identity=44.5121951219512, Blast_Score=280, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36040; Mature: 35909

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKVGINGFGRIGRLAFREIIKNEGIEVVAINDLTDTKMLAHLLKYDTTQGRFDGEVEV
CEEEECCCCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEEE
HDDHFLVNGEKVITLANRNPEELPWGDLGVDIVLECTGFFTSKEKAELHLKAGAKKVVIS
ECCEEEECCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCEEEEEE
APATGDMKTVVYNTNHDILDGTETVISGASCTTNCLAPMAKVLQDQFGIVEGLMTTIHAY
CCCCCCEEEEEECCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGDQNTLDAPHPKGDFRRARAAAANIVPNTTGAAKAIGLVIPELQGKLDGAAQRVPVATG
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHEEHHHHCCCCCCHHCCCCCCC
SLTELVTVLDKQVSVDEVNAAMKAAANESFGYTEDEIVSSDIVGITYGSLFDATQTKVMT
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEEEECCHHCCCCCEEEE
VGDKQLVKTVSWYDNEMSYTAQLVRTVKHFANIAK
ECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVKVGINGFGRIGRLAFREIIKNEGIEVVAINDLTDTKMLAHLLKYDTTQGRFDGEVEV
EEEECCCCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEEE
HDDHFLVNGEKVITLANRNPEELPWGDLGVDIVLECTGFFTSKEKAELHLKAGAKKVVIS
ECCEEEECCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCEEEEEE
APATGDMKTVVYNTNHDILDGTETVISGASCTTNCLAPMAKVLQDQFGIVEGLMTTIHAY
CCCCCCEEEEEECCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGDQNTLDAPHPKGDFRRARAAAANIVPNTTGAAKAIGLVIPELQGKLDGAAQRVPVATG
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHEEHHHHCCCCCCHHCCCCCCC
SLTELVTVLDKQVSVDEVNAAMKAAANESFGYTEDEIVSSDIVGITYGSLFDATQTKVMT
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEEEECCHHCCCCCEEEE
VGDKQLVKTVSWYDNEMSYTAQLVRTVKHFANIAK
ECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA