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The map label for this gene is ackA

Identifier: 229916414

GI number: 229916414

Start: 637310

End: 638521

Strand: Reverse

Name: ackA

Synonym: EAT1b_0684

Alternate gene names: 229916414

Gene position: 638521-637310 (Counterclockwise)

Preceding gene: 229916415

Following gene: 229916413

Centisome position: 21.28

GC content: 49.09

Gene sequence:

>1212_bases
ATGACGAAAATTATGGCAGTCAATGCGGGTAGTTCATCGCTCAAGTTCCAGTTACTCGAGATGCCAACGGAAGAGTTGCT
TGCAGTCGGACTCGTAGAGCGTGTAGGGAAAGAAGATGCGATTTTTACAATCAAGTACGGTGAAGGACAGAAGTTCAACG
TGGTCACACCACTTCACACGCACAAAGAAGCAGTTGAATTGACGTTGGAGAAGTTGATCGAGTTGGACATCATCCAATCA
TTCGATGAGATTTCTGGCGTAGGTCACCGTGTGTTACACGGAAAAGAGTTGTATGCGGATTCGGTCGTCATTGACGATGA
AGTCATGAAGAACATCGAGTCGTTCACCGAGCTCGGCCCACTTCATATCCCACCAAACTTGACAGGTATTCGCGCATTCC
AGGCAATTTTACCGAATGTCCCACAAGTAGCGGTATTCGATACAGCGTTCCACCAGTCAATGCCTGAAGAGAATTTCTTG
TACAGTCTTCCTTACGAATACTATACAGAACACGGTGTACGTAAATACGGCTTCCACGGAACGAGCCACAAGTATGTCAC
ACAGCGCGCGGCAGAACTTCTCGGTCGTCCGCTAGAAGACTTGCGTTTGATTTCATGTCACCTCGGTAGCGGTGCATCGA
TCGCTGCAGTAGCAGGTGGTCGCTCGATCGATACAACGATGGGCTTCACACCACTCGAAGGAATCACGATGGGAACGCGC
TCAGGTTCATTGGACCCGGCCCTCATCCCGTTCTTGATGCAAAAAACAGGGAAGTCTGCTGAAGACGTCTTGAACGTCAT
GAACAAAGAGTCTGGTGTGTACGGACTTTCTGGTATCTCAAGTGACTTGCGTGACATCGAGCAAGCGGCTGCAGAAGGCA
ACCATCGTGCAGAAGTTTCATTAAAAATCTTCTCGAACCGTATTCACGGTTACATCGGTCAATATGCGGCTGAAATGAAT
GGTGTCGACGCCATCATCTTCACTGCAGGTGTCGGAGAGAACTCGGACGTCATCCGTGAACGCATCCTTCGTGGTCTTGA
ATTCATGGGTGTCTACTGGGATCCTTCTCTTAACAACGGTGCTCGTGGGAAAGAGTTGTTCATCAACTACCCACACTCAC
CGGTTAAAGTCATCATCATCCCGACGAACGAAGAATTGGTCATCGCGCGTGACACGGTACGCATCGCAAACCTTGTCGAA
GCACACGCATAA

Upstream 100 bases:

>100_bases
AGGTATGCAAAATCAAGTATCTTCATTATGATACAGTTATCAGTTTTAAATTGAACAGATAAAGATATGCGTTTAAAACG
AAAGGTAAGAGGTGTATGAC

Downstream 100 bases:

>100_bases
TACGAAACGAACCCACGTTACTTCATGTAACGTGGGTTTTTTATGAGCCTTTTTGACTAATGCGAAGTAGAGACAGTAGG
ACAATTGTTTTCCTCTTTGT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTKIMAVNAGSSSLKFQLLEMPTEELLAVGLVERVGKEDAIFTIKYGEGQKFNVVTPLHTHKEAVELTLEKLIELDIIQS
FDEISGVGHRVLHGKELYADSVVIDDEVMKNIESFTELGPLHIPPNLTGIRAFQAILPNVPQVAVFDTAFHQSMPEENFL
YSLPYEYYTEHGVRKYGFHGTSHKYVTQRAAELLGRPLEDLRLISCHLGSGASIAAVAGGRSIDTTMGFTPLEGITMGTR
SGSLDPALIPFLMQKTGKSAEDVLNVMNKESGVYGLSGISSDLRDIEQAAAEGNHRAEVSLKIFSNRIHGYIGQYAAEMN
GVDAIIFTAGVGENSDVIRERILRGLEFMGVYWDPSLNNGARGKELFINYPHSPVKVIIIPTNEELVIARDTVRIANLVE
AHA

Sequences:

>Translated_403_residues
MTKIMAVNAGSSSLKFQLLEMPTEELLAVGLVERVGKEDAIFTIKYGEGQKFNVVTPLHTHKEAVELTLEKLIELDIIQS
FDEISGVGHRVLHGKELYADSVVIDDEVMKNIESFTELGPLHIPPNLTGIRAFQAILPNVPQVAVFDTAFHQSMPEENFL
YSLPYEYYTEHGVRKYGFHGTSHKYVTQRAAELLGRPLEDLRLISCHLGSGASIAAVAGGRSIDTTMGFTPLEGITMGTR
SGSLDPALIPFLMQKTGKSAEDVLNVMNKESGVYGLSGISSDLRDIEQAAAEGNHRAEVSLKIFSNRIHGYIGQYAAEMN
GVDAIIFTAGVGENSDVIRERILRGLEFMGVYWDPSLNNGARGKELFINYPHSPVKVIIIPTNEELVIARDTVRIANLVE
AHA
>Mature_402_residues
TKIMAVNAGSSSLKFQLLEMPTEELLAVGLVERVGKEDAIFTIKYGEGQKFNVVTPLHTHKEAVELTLEKLIELDIIQSF
DEISGVGHRVLHGKELYADSVVIDDEVMKNIESFTELGPLHIPPNLTGIRAFQAILPNVPQVAVFDTAFHQSMPEENFLY
SLPYEYYTEHGVRKYGFHGTSHKYVTQRAAELLGRPLEDLRLISCHLGSGASIAAVAGGRSIDTTMGFTPLEGITMGTRS
GSLDPALIPFLMQKTGKSAEDVLNVMNKESGVYGLSGISSDLRDIEQAAAEGNHRAEVSLKIFSNRIHGYIGQYAAEMNG
VDAIIFTAGVGENSDVIRERILRGLEFMGVYWDPSLNNGARGKELFINYPHSPVKVIIIPTNEELVIARDTVRIANLVEA
HA

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI145693184, Length=397, Percent_Identity=42.8211586901763, Blast_Score=328, Evalue=4e-91,
Organism=Escherichia coli, GI1788633, Length=396, Percent_Identity=41.9191919191919, Blast_Score=310, Evalue=9e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACKA_EXISA (C4L493)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002885060.1
- GeneID:   7871456
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_0684
- OMA:   TDEEYMI
- ProtClustDB:   PRK00180
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PANTHER:   PTHR21060:SF11
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 44237; Mature: 44106

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIMAVNAGSSSLKFQLLEMPTEELLAVGLVERVGKEDAIFTIKYGEGQKFNVVTPLHT
CCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCHH
HKEAVELTLEKLIELDIIQSFDEISGVGHRVLHGKELYADSVVIDDEVMKNIESFTELGP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHCCCEEECHHHHHHHHHHHHCCC
LHIPPNLTGIRAFQAILPNVPQVAVFDTAFHQSMPEENFLYSLPYEYYTEHGVRKYGFHG
EECCCCCHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCCCEEECCHHHHHHCCCEECCCCC
TSHKYVTQRAAELLGRPLEDLRLISCHLGSGASIAAVAGGRSIDTTMGFTPLEGITMGTR
CCHHHHHHHHHHHHCCCHHHHEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEECCC
SGSLDPALIPFLMQKTGKSAEDVLNVMNKESGVYGLSGISSDLRDIEQAAAEGNHRAEVS
CCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHCCCCEEEEE
LKIFSNRIHGYIGQYAAEMNGVDAIIFTAGVGENSDVIRERILRGLEFMGVYWDPSLNNG
EEEHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCHHHEEEEECCCCCCC
ARGKELFINYPHSPVKVIIIPTNEELVIARDTVRIANLVEAHA
CCCCEEEEECCCCCEEEEEEECCCCEEEEECHHHHHHHHHHCC
>Mature Secondary Structure 
TKIMAVNAGSSSLKFQLLEMPTEELLAVGLVERVGKEDAIFTIKYGEGQKFNVVTPLHT
CEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCHH
HKEAVELTLEKLIELDIIQSFDEISGVGHRVLHGKELYADSVVIDDEVMKNIESFTELGP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHCCCEEECHHHHHHHHHHHHCCC
LHIPPNLTGIRAFQAILPNVPQVAVFDTAFHQSMPEENFLYSLPYEYYTEHGVRKYGFHG
EECCCCCHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCCCEEECCHHHHHHCCCEECCCCC
TSHKYVTQRAAELLGRPLEDLRLISCHLGSGASIAAVAGGRSIDTTMGFTPLEGITMGTR
CCHHHHHHHHHHHHCCCHHHHEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEECCC
SGSLDPALIPFLMQKTGKSAEDVLNVMNKESGVYGLSGISSDLRDIEQAAAEGNHRAEVS
CCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHCCCCEEEEE
LKIFSNRIHGYIGQYAAEMNGVDAIIFTAGVGENSDVIRERILRGLEFMGVYWDPSLNNG
EEEHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCHHHEEEEECCCCCCC
ARGKELFINYPHSPVKVIIIPTNEELVIARDTVRIANLVEAHA
CCCCEEEEECCCCCEEEEEEECCCCEEEEECHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA