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The map label for this gene is rsbP [H]

Identifier: 229916205

GI number: 229916205

Start: 432045

End: 433157

Strand: Reverse

Name: rsbP [H]

Synonym: EAT1b_0474

Alternate gene names: 229916205

Gene position: 433157-432045 (Counterclockwise)

Preceding gene: 229916207

Following gene: 229916203

Centisome position: 14.44

GC content: 49.78

Gene sequence:

>1113_bases
ATGGCGATTTTGATTGTGGATGATGAACCGGTCAATACGCTCGTACTCGAGCAACTGCTTCACCAGCACGACTATGAGAC
GGTATCGGTCTCGAGCGGGGAAGAAGCGCTCGACTTACTGATGGCCCCACAAGCTGCATCGCTGTATGATCTCGTCCTGT
TGGATGTCGAAATGCCTGGAATTTCAGGAATCGAGACGTGCAAACGGATTCGGCAGATGGCTGACTTTGAAGAGTTGCCG
GTCATCATGGTTTCCGGACGAACGGAAGAGAAGCAGATTGCCGAGGGGCTCGACGCGGAGGCGTCAGATTACACGACCAA
ACCGATCAAAATAACAGAATTACTTGCAAGAATCCGTTCTGCTCTCCGTTATAAGGCGGCTGTTGATGAACGGAAAATTT
ATGAGGCCCGTCTTCAGTATGATTTAGACCTCGCCCAGAAGATTCAACAAAGCGCGCTTACGCCACCAATCAGTAATGAA
GAGATTGATGTTCGGGCGCTCTATCTACCTTCTAAAAAACTAGCCGGAGACATGTACGCGTGGTTTCAGGTCGCACCGGA
CCGATACGGGGTCATCATCTTTGACGTCATGGGACATGGGGTCTCATCGGCGCTCATCACGATGGGAATCCGTTCCATCC
TACCGGGCCTTGTCGGGAACGTGCAATATCCGGTAGACGTCATGACGGAGTTGAACCGTCAGATGACGTTCCTCTTCTCG
GGTGACGATATGCATAGCTATTTCACGGCGGTCTATTGTTACATCGACACGACAAAGCGTCGAATTGAATATGTGAATGC
AGGCCATCCCCCTGTGATCGTGACGTCAGAAGAAGGAAACTGTCGTCTCGAGACGACAGGAGTACCAGTTGGCATGTTCG
AGGAACCGAATTATGAGTCGAAAGAGATTGACATCACGCCGAATATGATGCTTCACATGTATACAGATGGACTCATGGAG
TGTTACAGCAAAGATATCGATGATGGGATTCGCTGGCTAGAGAAGGACGTTGTCACATACGGTTTGGACTATAGTCGTCA
CGTCGCTGAACAGCTTGTGCCAAAGATTGAGATTGAAGACGATCTGTGTCTCGTCACGGTCAAAATCACATGA

Upstream 100 bases:

>100_bases
GGTTCTTCAACTAGAATGAACAGACGGTTATGTCGTGTGTGAATGAAAAGATATGGTACAATACGATATAGATTAATACG
TAGAGAAGGAAGGGATAGTC

Downstream 100 bases:

>100_bases
AGAGAGCCTGACGCAATATGCGTCAGGCTCTTGGTCGCTAAAAATATCGCTTTCGCCAAAGAATATAAAAGGCGAGACCG
GAAAATCCAATCATCATCGT

Product: response regulator receiver modulated serine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MAILIVDDEPVNTLVLEQLLHQHDYETVSVSSGEEALDLLMAPQAASLYDLVLLDVEMPGISGIETCKRIRQMADFEELP
VIMVSGRTEEKQIAEGLDAEASDYTTKPIKITELLARIRSALRYKAAVDERKIYEARLQYDLDLAQKIQQSALTPPISNE
EIDVRALYLPSKKLAGDMYAWFQVAPDRYGVIIFDVMGHGVSSALITMGIRSILPGLVGNVQYPVDVMTELNRQMTFLFS
GDDMHSYFTAVYCYIDTTKRRIEYVNAGHPPVIVTSEEGNCRLETTGVPVGMFEEPNYESKEIDITPNMMLHMYTDGLME
CYSKDIDDGIRWLEKDVVTYGLDYSRHVAEQLVPKIEIEDDLCLVTVKIT

Sequences:

>Translated_370_residues
MAILIVDDEPVNTLVLEQLLHQHDYETVSVSSGEEALDLLMAPQAASLYDLVLLDVEMPGISGIETCKRIRQMADFEELP
VIMVSGRTEEKQIAEGLDAEASDYTTKPIKITELLARIRSALRYKAAVDERKIYEARLQYDLDLAQKIQQSALTPPISNE
EIDVRALYLPSKKLAGDMYAWFQVAPDRYGVIIFDVMGHGVSSALITMGIRSILPGLVGNVQYPVDVMTELNRQMTFLFS
GDDMHSYFTAVYCYIDTTKRRIEYVNAGHPPVIVTSEEGNCRLETTGVPVGMFEEPNYESKEIDITPNMMLHMYTDGLME
CYSKDIDDGIRWLEKDVVTYGLDYSRHVAEQLVPKIEIEDDLCLVTVKIT
>Mature_369_residues
AILIVDDEPVNTLVLEQLLHQHDYETVSVSSGEEALDLLMAPQAASLYDLVLLDVEMPGISGIETCKRIRQMADFEELPV
IMVSGRTEEKQIAEGLDAEASDYTTKPIKITELLARIRSALRYKAAVDERKIYEARLQYDLDLAQKIQQSALTPPISNEE
IDVRALYLPSKKLAGDMYAWFQVAPDRYGVIIFDVMGHGVSSALITMGIRSILPGLVGNVQYPVDVMTELNRQMTFLFSG
DDMHSYFTAVYCYIDTTKRRIEYVNAGHPPVIVTSEEGNCRLETTGVPVGMFEEPNYESKEIDITPNMMLHMYTDGLMEC
YSKDIDDGIRWLEKDVVTYGLDYSRHVAEQLVPKIEIEDDLCLVTVKIT

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to energy stress [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=124, Percent_Identity=36.2903225806452, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786599, Length=122, Percent_Identity=36.0655737704918, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788394, Length=121, Percent_Identity=34.7107438016529, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082012, Length=130, Percent_Identity=31.5384615384615, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787229, Length=120, Percent_Identity=34.1666666666667, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786784, Length=170, Percent_Identity=27.6470588235294, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786911, Length=78, Percent_Identity=44.8717948717949, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789149, Length=125, Percent_Identity=33.6, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR001932
- InterPro:   IPR010822 [H]

Pfam domain/function: PF00989 PAS; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 41727; Mature: 41596

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILIVDDEPVNTLVLEQLLHQHDYETVSVSSGEEALDLLMAPQAASLYDLVLLDVEMPG
CEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCEEEEEEEEEECCC
ISGIETCKRIRQMADFEELPVIMVSGRTEEKQIAEGLDAEASDYTTKPIKITELLARIRS
CCHHHHHHHHHHHCCHHHCCEEEEECCCHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHH
ALRYKAAVDERKIYEARLQYDLDLAQKIQQSALTPPISNEEIDVRALYLPSKKLAGDMYA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHCCCCEE
WFQVAPDRYGVIIFDVMGHGVSSALITMGIRSILPGLVGNVQYPVDVMTELNRQMTFLFS
EEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEEEEC
GDDMHSYFTAVYCYIDTTKRRIEYVNAGHPPVIVTSEEGNCRLETTGVPVGMFEEPNYES
CCCHHHHEEEEEEEEECCHHHHEEECCCCCCEEEECCCCCEEEEECCCCEECCCCCCCCC
KEIDITPNMMLHMYTDGLMECYSKDIDDGIRWLEKDVVTYGLDYSRHVAEQLVPKIEIED
CEEEECCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEECC
DLCLVTVKIT
CEEEEEEEEC
>Mature Secondary Structure 
AILIVDDEPVNTLVLEQLLHQHDYETVSVSSGEEALDLLMAPQAASLYDLVLLDVEMPG
EEEEECCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCEEEEEEEEEECCC
ISGIETCKRIRQMADFEELPVIMVSGRTEEKQIAEGLDAEASDYTTKPIKITELLARIRS
CCHHHHHHHHHHHCCHHHCCEEEEECCCHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHH
ALRYKAAVDERKIYEARLQYDLDLAQKIQQSALTPPISNEEIDVRALYLPSKKLAGDMYA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHCCCCEE
WFQVAPDRYGVIIFDVMGHGVSSALITMGIRSILPGLVGNVQYPVDVMTELNRQMTFLFS
EEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEEEEC
GDDMHSYFTAVYCYIDTTKRRIEYVNAGHPPVIVTSEEGNCRLETTGVPVGMFEEPNYES
CCCHHHHEEEEEEEEECCHHHHEEECCCCCCEEEECCCCCEEEEECCCCEECCCCCCCCC
KEIDITPNMMLHMYTDGLMECYSKDIDDGIRWLEKDVVTYGLDYSRHVAEQLVPKIEIED
CEEEECCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEECC
DLCLVTVKIT
CEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 10632888 [H]