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The map label for this gene is htpG [H]

Identifier: 229587207

GI number: 229587207

Start: 1214002

End: 1215867

Strand: Direct

Name: htpG [H]

Synonym: RAF_ORF1192

Alternate gene names: 229587207

Gene position: 1214002-1215867 (Clockwise)

Preceding gene: 229587206

Following gene: 229587208

Centisome position: 94.95

GC content: 33.01

Gene sequence:

>1866_bases
ATGATACAAGAAAAAAAGAAATTTGATGCCGAGGTTGGCAAGATTTTAAATTTAATGATTCACTCTCTTTATAGTAATAA
AGAGATTTTTATGAGGGAGTTAATTTCCAATGCTTCGGATGCTTGTGATAAATTACGTTATTTATCTCAAAGTAATAGTG
AATTAGTAGCTGGCGATAGCAATTTTAAAATTACAGTTAAAGTCGATAAAGATAACAGACAAATCATTATCCGTGATAAT
GGCATCGGCATGCATAAAGACGATTTAATTGAAAATCTCGGTACTATTGCAAGATCGGGTACGGCAAATTTTCTTAAAAG
CCTATCCGGTGATTCTAAAAAAAACAATATGCTAATCGGTCAATTTGGTGTTGGATTTTATTCAAGCTTTATGGTAGCCG
ATAAAGTGACTGTAACCTCAAGAAAAGCTGGGGAAGATAAAGTCCATATTTGGGAATCAGACGGACTTGGTGAATATACT
GTCTCAGATTCAGATAAAGAGTTCACAAGAGGCACGGAAATCGTTTTACATATAAAAACGGAAGAAGATACATTCCTTGA
TCATTTTAGATTAAAACACATCGTTAAAAGCTATTCCGATCACATAGCAGTACCAATATATTTCTTTGATGAAGCTGGTA
ATAATGAAATCCAGCTTAATTCAGCTTCTGCATTATGGACAAGACCGAAATCGGAAATTACGGAAGAACAATATAAAGAA
TTCTACAAAAGTCTATCTTATGCCATTGATGACCCTTGGATAACTATGCATAATAAAAACGAGGGAGCTATAGAATTTAC
TAACCTACTTTTCATTCCATCAAGCAAAACATTTGATTTATTCCACCCTGATCGCAAAAGGCGAGTAAAATTATATATAA
AAAGAGTATTTATATCTGATGAGAATATAGATTTAATCCCGTCATATTTAAGATTTTTACGAGGCGTGGTTGATTCAGAA
GATTTACCACTAAATATTAGCCGTGAATCACTGCAGCATAATAGCGTACTTGAGAAAATCAAAAATGCTATTACAAAAAG
AGTGCTCGGCGAGCTTAGAAAAAAGAAAGAGGAATCACCTGAAGAATATAATAAGTTTTGGACTAATTTCGGCGGTGCTT
TAAAAGAGGGTTTATGTGAGGCTACTACCAACCATGAAAAATTATTAGAGGTATGCATATTCAGAAGTGCCTTGCATAAT
AAAATGATCAGCCTTGACGAATATATAGCGAATTTTAAAGAAGGGCAGAGTACTATATATTATTTAAGCGGTGATAACCC
CGATAAATTACTTTCAAGCCCACAAATCGAAGGGTTGTTAAGTAAAAAAATCGATGTATTACTTTTTACCGATACAGTGG
ATGATTTTTGGGTAAATGTTAATAGCAAATATAAAGAACATGCTATTAAATCAGCGACAAGAAGCGATATCGATGTAGAG
CAAACTACTTCACAATCTGAGGAGAAAAATACAGATAGTAAAAAATCCGATGATGAATATAAATTGCTAACAGATTATTT
TAAAGAGACACTAGGGGAGTTGGTAAAAGAAGTTAAGATCTCTAAAAAACTTACTTCAAGTCCTGCTTGTCTTGCCGTTA
GCGACGCTGCTATGGATATTCGTATGGAGAGATTTTTGATTGAACAGAAACAAATAGCTAATGCCTCAGCTAAAAATCTA
GAGTTAAACCCTAAAAATAAAATCATAGAGAAAATCTTTAACGACTTAAAAGCAAATAATAAAAATAATGAAGAATTGGT
TAATCTAATATTTGATCAAGCCTGTATTTTAGAGGGTGAACCGGTTGCTGATACAGGTGCATTTTCAAAGAGATTAAACG
ATATTGTACAAAAAGCCATATTATAA

Upstream 100 bases:

>100_bases
GGGAATCCAGTTTATATTTATTATTTTCTAGATTCCTGCTTCCGCAGGAATGACATAAGCAGTCATATGACGAAAAAATA
ATTTATTAACTGGAATAATT

Downstream 100 bases:

>100_bases
CTTTAAACTTTTTTAATTTTAATGTAGAATAGTTGCAAACGTCAGTTTGGAAGTATTGTTCTGTTCGATGTCATTCCCGC
GTAGGCGGGAATCTAGAAAG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MIQEKKKFDAEVGKILNLMIHSLYSNKEIFMRELISNASDACDKLRYLSQSNSELVAGDSNFKITVKVDKDNRQIIIRDN
GIGMHKDDLIENLGTIARSGTANFLKSLSGDSKKNNMLIGQFGVGFYSSFMVADKVTVTSRKAGEDKVHIWESDGLGEYT
VSDSDKEFTRGTEIVLHIKTEEDTFLDHFRLKHIVKSYSDHIAVPIYFFDEAGNNEIQLNSASALWTRPKSEITEEQYKE
FYKSLSYAIDDPWITMHNKNEGAIEFTNLLFIPSSKTFDLFHPDRKRRVKLYIKRVFISDENIDLIPSYLRFLRGVVDSE
DLPLNISRESLQHNSVLEKIKNAITKRVLGELRKKKEESPEEYNKFWTNFGGALKEGLCEATTNHEKLLEVCIFRSALHN
KMISLDEYIANFKEGQSTIYYLSGDNPDKLLSSPQIEGLLSKKIDVLLFTDTVDDFWVNVNSKYKEHAIKSATRSDIDVE
QTTSQSEEKNTDSKKSDDEYKLLTDYFKETLGELVKEVKISKKLTSSPACLAVSDAAMDIRMERFLIEQKQIANASAKNL
ELNPKNKIIEKIFNDLKANNKNNEELVNLIFDQACILEGEPVADTGAFSKRLNDIVQKAIL

Sequences:

>Translated_621_residues
MIQEKKKFDAEVGKILNLMIHSLYSNKEIFMRELISNASDACDKLRYLSQSNSELVAGDSNFKITVKVDKDNRQIIIRDN
GIGMHKDDLIENLGTIARSGTANFLKSLSGDSKKNNMLIGQFGVGFYSSFMVADKVTVTSRKAGEDKVHIWESDGLGEYT
VSDSDKEFTRGTEIVLHIKTEEDTFLDHFRLKHIVKSYSDHIAVPIYFFDEAGNNEIQLNSASALWTRPKSEITEEQYKE
FYKSLSYAIDDPWITMHNKNEGAIEFTNLLFIPSSKTFDLFHPDRKRRVKLYIKRVFISDENIDLIPSYLRFLRGVVDSE
DLPLNISRESLQHNSVLEKIKNAITKRVLGELRKKKEESPEEYNKFWTNFGGALKEGLCEATTNHEKLLEVCIFRSALHN
KMISLDEYIANFKEGQSTIYYLSGDNPDKLLSSPQIEGLLSKKIDVLLFTDTVDDFWVNVNSKYKEHAIKSATRSDIDVE
QTTSQSEEKNTDSKKSDDEYKLLTDYFKETLGELVKEVKISKKLTSSPACLAVSDAAMDIRMERFLIEQKQIANASAKNL
ELNPKNKIIEKIFNDLKANNKNNEELVNLIFDQACILEGEPVADTGAFSKRLNDIVQKAIL
>Mature_621_residues
MIQEKKKFDAEVGKILNLMIHSLYSNKEIFMRELISNASDACDKLRYLSQSNSELVAGDSNFKITVKVDKDNRQIIIRDN
GIGMHKDDLIENLGTIARSGTANFLKSLSGDSKKNNMLIGQFGVGFYSSFMVADKVTVTSRKAGEDKVHIWESDGLGEYT
VSDSDKEFTRGTEIVLHIKTEEDTFLDHFRLKHIVKSYSDHIAVPIYFFDEAGNNEIQLNSASALWTRPKSEITEEQYKE
FYKSLSYAIDDPWITMHNKNEGAIEFTNLLFIPSSKTFDLFHPDRKRRVKLYIKRVFISDENIDLIPSYLRFLRGVVDSE
DLPLNISRESLQHNSVLEKIKNAITKRVLGELRKKKEESPEEYNKFWTNFGGALKEGLCEATTNHEKLLEVCIFRSALHN
KMISLDEYIANFKEGQSTIYYLSGDNPDKLLSSPQIEGLLSKKIDVLLFTDTVDDFWVNVNSKYKEHAIKSATRSDIDVE
QTTSQSEEKNTDSKKSDDEYKLLTDYFKETLGELVKEVKISKKLTSSPACLAVSDAAMDIRMERFLIEQKQIANASAKNL
ELNPKNKIIEKIFNDLKANNKNNEELVNLIFDQACILEGEPVADTGAFSKRLNDIVQKAIL

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI4507677, Length=684, Percent_Identity=33.187134502924, Blast_Score=374, Evalue=1e-103,
Organism=Homo sapiens, GI155722983, Length=629, Percent_Identity=33.2273449920509, Blast_Score=338, Evalue=8e-93,
Organism=Homo sapiens, GI20149594, Length=410, Percent_Identity=34.8780487804878, Blast_Score=223, Evalue=4e-58,
Organism=Homo sapiens, GI154146191, Length=410, Percent_Identity=33.9024390243902, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI153792590, Length=411, Percent_Identity=34.0632603406326, Blast_Score=219, Evalue=5e-57,
Organism=Escherichia coli, GI1786679, Length=625, Percent_Identity=43.04, Blast_Score=509, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI17559162, Length=669, Percent_Identity=35.575485799701, Blast_Score=377, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17542208, Length=672, Percent_Identity=33.4821428571429, Blast_Score=375, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI115535205, Length=641, Percent_Identity=31.6692667706708, Blast_Score=296, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI115535167, Length=425, Percent_Identity=35.2941176470588, Blast_Score=251, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6323840, Length=410, Percent_Identity=34.1463414634146, Blast_Score=237, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6325016, Length=410, Percent_Identity=33.9024390243902, Blast_Score=233, Evalue=5e-62,
Organism=Drosophila melanogaster, GI21357739, Length=687, Percent_Identity=32.7510917030568, Blast_Score=357, Evalue=2e-98,
Organism=Drosophila melanogaster, GI24586016, Length=618, Percent_Identity=34.789644012945, Blast_Score=327, Evalue=1e-89,
Organism=Drosophila melanogaster, GI17647529, Length=392, Percent_Identity=35.4591836734694, Blast_Score=228, Evalue=1e-59,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 70835; Mature: 70835

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQEKKKFDAEVGKILNLMIHSLYSNKEIFMRELISNASDACDKLRYLSQSNSELVAGDS
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEECCC
NFKITVKVDKDNRQIIIRDNGIGMHKDDLIENLGTIARSGTANFLKSLSGDSKKNNMLIG
CEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEE
QFGVGFYSSFMVADKVTVTSRKAGEDKVHIWESDGLGEYTVSDSDKEFTRGTEIVLHIKT
ECCHHHHHHHHHHCEEEEECCCCCCCCEEEEECCCCCCEEECCCCCHHCCCCEEEEEEEC
EEDTFLDHFRLKHIVKSYSDHIAVPIYFFDEAGNNEIQLNSASALWTRPKSEITEEQYKE
CCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEECCHHHHCCCHHHHHHHHHHH
FYKSLSYAIDDPWITMHNKNEGAIEFTNLLFIPSSKTFDLFHPDRKRRVKLYIKRVFISD
HHHHHHHHCCCCEEEEECCCCCCEEEEEEEEECCCCEEECCCCCHHHHHHHHHHHHEECC
ENIDLIPSYLRFLRGVVDSEDLPLNISRESLQHNSVLEKIKNAITKRVLGELRKKKEESP
CCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EEYNKFWTNFGGALKEGLCEATTNHEKLLEVCIFRSALHNKMISLDEYIANFKEGQSTIY
HHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
YLSGDNPDKLLSSPQIEGLLSKKIDVLLFTDTVDDFWVNVNSKYKEHAIKSATRSDIDVE
EEECCCHHHHHCCCCHHHHHHCCCEEEEEECCCCCCEEECCCHHHHHHHHHHHCCCCCHH
QTTSQSEEKNTDSKKSDDEYKLLTDYFKETLGELVKEVKISKKLTSSPACLAVSDAAMDI
HHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHH
RMERFLIEQKQIANASAKNLELNPKNKIIEKIFNDLKANNKNNEELVNLIFDQACILEGE
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCC
PVADTGAFSKRLNDIVQKAIL
CCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIQEKKKFDAEVGKILNLMIHSLYSNKEIFMRELISNASDACDKLRYLSQSNSELVAGDS
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEECCC
NFKITVKVDKDNRQIIIRDNGIGMHKDDLIENLGTIARSGTANFLKSLSGDSKKNNMLIG
CEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEE
QFGVGFYSSFMVADKVTVTSRKAGEDKVHIWESDGLGEYTVSDSDKEFTRGTEIVLHIKT
ECCHHHHHHHHHHCEEEEECCCCCCCCEEEEECCCCCCEEECCCCCHHCCCCEEEEEEEC
EEDTFLDHFRLKHIVKSYSDHIAVPIYFFDEAGNNEIQLNSASALWTRPKSEITEEQYKE
CCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEECCHHHHCCCHHHHHHHHHHH
FYKSLSYAIDDPWITMHNKNEGAIEFTNLLFIPSSKTFDLFHPDRKRRVKLYIKRVFISD
HHHHHHHHCCCCEEEEECCCCCCEEEEEEEEECCCCEEECCCCCHHHHHHHHHHHHEECC
ENIDLIPSYLRFLRGVVDSEDLPLNISRESLQHNSVLEKIKNAITKRVLGELRKKKEESP
CCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EEYNKFWTNFGGALKEGLCEATTNHEKLLEVCIFRSALHNKMISLDEYIANFKEGQSTIY
HHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
YLSGDNPDKLLSSPQIEGLLSKKIDVLLFTDTVDDFWVNVNSKYKEHAIKSATRSDIDVE
EEECCCHHHHHCCCCHHHHHHCCCEEEEEECCCCCCEEECCCHHHHHHHHHHHCCCCCHH
QTTSQSEEKNTDSKKSDDEYKLLTDYFKETLGELVKEVKISKKLTSSPACLAVSDAAMDI
HHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHH
RMERFLIEQKQIANASAKNLELNPKNKIIEKIFNDLKANNKNNEELVNLIFDQACILEGE
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCC
PVADTGAFSKRLNDIVQKAIL
CCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA