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The map label for this gene is mraY2 [H]

Identifier: 229587189

GI number: 229587189

Start: 1197202

End: 1198185

Strand: Direct

Name: mraY2 [H]

Synonym: RAF_ORF1172

Alternate gene names: 229587189

Gene position: 1197202-1198185 (Clockwise)

Preceding gene: 229587188

Following gene: 229587190

Centisome position: 93.64

GC content: 30.49

Gene sequence:

>984_bases
ATGAATATAAATAGCTACAGCACATTATTTATTTTTTCTTTTATATCCACCTCTATATTAACATATATATTAACTAAATA
TCTTCCTACTATCGGTTTAGTTGATATACCAAGTAACCGTCGTTCTCATGATAAGATAACACCACGCGGCGGCGGTCTTG
CTATTGTAGTTGTTGTAATGATTGCTTTGAGCGGGTTTGAATATATAACGAGCAACAACTTTGTTAATTCAATAAAAATA
TTACCGTTATTATTGGCAATTGCTTCGATTTCCTTTTTAGATGACTTAAAAGCCGTACCTATTCTAATTCGTTTAATAGT
CCACTTAATTTGTGCAGCTTTTGCTATTTTTCTTTTTTCGCAGCTAAACTCTGTACATATACTAATATATTCTATTTTAG
TTATAGCTTTAAGCGGTTTTATTAATATATATAATTTTATGGACGGTATAGACGGTATGAGTTGTGTGGAATCTATCCAT
CTATCTAGCACTATGCTTATATTATGTTTTTTACAATTTCCGACTATTAATAATCCATATTTTATAACTAGTGTAAATGT
TATTATTCTTGGTGGCTCTTGTGGTTTTTTAATATTTAATTGGCATCCGGCAAAAATATTTTTAGGAGACGTGGGAAGTA
TTAGTCTTGGATTCTTAACGGGTCTTTGTTTGCTCCTGCTGGCTCTTACAAGCACTAATTTATTTATAGCTTGTGCTATT
GCTAGCTTATATTACATCACTGATGCAGTGCTAACCATATTAATTCGGCTACTCAATAAAGAAAAAATTTGGCAGCCTCA
TTTAAAACATTTTTTTCAAAAAGCAGTACAAAAAGGTAAATCTCATAAACAAGTAGTATCGATTATAGCAGTTTGTAATA
TATTTTTAATGATCATATCGGTTACATCTTTACATTTTCCCGTAATATCTATAATGCTTGCTTTAGCAGTCATAACTTTA
ACAGTGCAGAGTTTATTAAAATGA

Upstream 100 bases:

>100_bases
GGTAGCCCTGAACCTTCAAAAGCCAACATTCATATGACAAATAAGATAGTAGAGATATGCCAAACCGTAAATATTATAGT
TTTAAATCTAATATGTTCCT

Downstream 100 bases:

>100_bases
AGCTAATTAAAGAGGATATTGATAAAATAGTTAGACGTATATTTGCTAAACAACATCCATTGCTGCCTGAAATCATGATT
AACTGGAATAAAATAGTCGG

Product: Undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase

Products: Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine; UMP [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MNINSYSTLFIFSFISTSILTYILTKYLPTIGLVDIPSNRRSHDKITPRGGGLAIVVVVMIALSGFEYITSNNFVNSIKI
LPLLLAIASISFLDDLKAVPILIRLIVHLICAAFAIFLFSQLNSVHILIYSILVIALSGFINIYNFMDGIDGMSCVESIH
LSSTMLILCFLQFPTINNPYFITSVNVIILGGSCGFLIFNWHPAKIFLGDVGSISLGFLTGLCLLLLALTSTNLFIACAI
ASLYYITDAVLTILIRLLNKEKIWQPHLKHFFQKAVQKGKSHKQVVSIIAVCNIFLMIISVTSLHFPVISIMLALAVITL
TVQSLLK

Sequences:

>Translated_327_residues
MNINSYSTLFIFSFISTSILTYILTKYLPTIGLVDIPSNRRSHDKITPRGGGLAIVVVVMIALSGFEYITSNNFVNSIKI
LPLLLAIASISFLDDLKAVPILIRLIVHLICAAFAIFLFSQLNSVHILIYSILVIALSGFINIYNFMDGIDGMSCVESIH
LSSTMLILCFLQFPTINNPYFITSVNVIILGGSCGFLIFNWHPAKIFLGDVGSISLGFLTGLCLLLLALTSTNLFIACAI
ASLYYITDAVLTILIRLLNKEKIWQPHLKHFFQKAVQKGKSHKQVVSIIAVCNIFLMIISVTSLHFPVISIMLALAVITL
TVQSLLK
>Mature_327_residues
MNINSYSTLFIFSFISTSILTYILTKYLPTIGLVDIPSNRRSHDKITPRGGGLAIVVVVMIALSGFEYITSNNFVNSIKI
LPLLLAIASISFLDDLKAVPILIRLIVHLICAAFAIFLFSQLNSVHILIYSILVIALSGFINIYNFMDGIDGMSCVESIH
LSSTMLILCFLQFPTINNPYFITSVNVIILGGSCGFLIFNWHPAKIFLGDVGSISLGFLTGLCLLLLALTSTNLFIACAI
ASLYYITDAVLTILIRLLNKEKIWQPHLKHFFQKAVQKGKSHKQVVSIIAVCNIFLMIISVTSLHFPVISIMLALAVITL
TVQSLLK

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.13 [C]

Molecular weight: Translated: 36034; Mature: 36034

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINSYSTLFIFSFISTSILTYILTKYLPTIGLVDIPSNRRSHDKITPRGGGLAIVVVVM
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHH
IALSGFEYITSNNFVNSIKILPLLLAIASISFLDDLKAVPILIRLIVHLICAAFAIFLFS
HHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLNSVHILIYSILVIALSGFINIYNFMDGIDGMSCVESIHLSSTMLILCFLQFPTINNPY
HHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
FITSVNVIILGGSCGFLIFNWHPAKIFLGDVGSISLGFLTGLCLLLLALTSTNLFIACAI
EEEEEEEEEECCCCCEEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
ASLYYITDAVLTILIRLLNKEKIWQPHLKHFFQKAVQKGKSHKQVVSIIAVCNIFLMIIS
HHHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VTSLHFPVISIMLALAVITLTVQSLLK
HHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNINSYSTLFIFSFISTSILTYILTKYLPTIGLVDIPSNRRSHDKITPRGGGLAIVVVVM
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHH
IALSGFEYITSNNFVNSIKILPLLLAIASISFLDDLKAVPILIRLIVHLICAAFAIFLFS
HHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLNSVHILIYSILVIALSGFINIYNFMDGIDGMSCVESIHLSSTMLILCFLQFPTINNPY
HHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
FITSVNVIILGGSCGFLIFNWHPAKIFLGDVGSISLGFLTGLCLLLLALTSTNLFIACAI
EEEEEEEEEECCCCCEEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
ASLYYITDAVLTILIRLLNKEKIWQPHLKHFFQKAVQKGKSHKQVVSIIAVCNIFLMIIS
HHHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VTSLHFPVISIMLALAVITLTVQSLLK
HHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Undecaprenyl phosphate; UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine [C]

Specific reaction: Undecaprenyl phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine --> Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP [C]

General reaction: Substituted phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]