Click here to switch to the map view.

The map label for this gene is ccmA [H]

Identifier: 229587156

GI number: 229587156

Start: 1142650

End: 1143309

Strand: Direct

Name: ccmA [H]

Synonym: RAF_ORF1119

Alternate gene names: 229587156

Gene position: 1142650-1143309 (Clockwise)

Preceding gene: 229587155

Following gene: 229587175

Centisome position: 89.37

GC content: 33.18

Gene sequence:

>660_bases
TTGACCACGATATCTAGTAAAATTATTAGTATTTTGAATTGCTTTTATATGGATACCGTGGTCAAGCTACGGTATAACAA
GGACATGCTATCACTTCATCAATTACAATTTAAAAACTTATTTGATCTAAATATTACTTTTCTTCCTTCTTCTATAACAT
ATATAAAAGGAGCTAACGGTTGTGGGAAAAGCTCGTTGCTACGAATGATAGCAGGAATTATGCAACCGAGTAGCGGTCAT
ATCTACTATAGAAACTGTAATATTAACAATATCGCTAAACTTTACTGCACTTATATCGGTCATAATTTAGGTCTAAAATC
AGAAATGACTGTTTTTGAGAATCTAAAATTTTGGTCAGAAATTTATAATTCCGCTGCAACCCTATATGCTGCTATTCATT
ACTTCAAATTACACGACTTATTAGATAAAAAATGCTATAGTTTGTCTAGCGGAATGCAGAAAATCGTAGCCATAGCAAGG
CTTATTGCTTGCCAATCTGACCTATGGCTACTTGATGAAGTTGAAACTAACTTAAGCAAAGAAAATAGGGCTTTACTCAA
TAATCTAATTGTCATGAAAGCAAATAGCGGCGGTATTGTTCTTCTATCCTCTCATCTAGAAAGCTCTATAAAATCTGCAC
AGATATTACGGCTTGATTAA

Upstream 100 bases:

>100_bases
GTCATAATAATCAACAAGATAATACAGAATTAACGGACCACACCAGAAGAGCATCATGAAAATTAAATTTATTAAAAAGC
AACAGATGTAATACCGTGGC

Downstream 100 bases:

>100_bases
TTATTATTGTTTTGCGTATTTTTATAAATCTCCCAATGTACAATAAAAAATATAAGGCTAACTATAATCCAAATTGAACA
ATTAATTATTGTACTTACAG

Product: cytochrome c biogenesis protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MTTISSKIISILNCFYMDTVVKLRYNKDMLSLHQLQFKNLFDLNITFLPSSITYIKGANGCGKSSLLRMIAGIMQPSSGH
IYYRNCNINNIAKLYCTYIGHNLGLKSEMTVFENLKFWSEIYNSAATLYAAIHYFKLHDLLDKKCYSLSSGMQKIVAIAR
LIACQSDLWLLDEVETNLSKENRALLNNLIVMKANSGGIVLLSSHLESSIKSAQILRLD

Sequences:

>Translated_219_residues
MTTISSKIISILNCFYMDTVVKLRYNKDMLSLHQLQFKNLFDLNITFLPSSITYIKGANGCGKSSLLRMIAGIMQPSSGH
IYYRNCNINNIAKLYCTYIGHNLGLKSEMTVFENLKFWSEIYNSAATLYAAIHYFKLHDLLDKKCYSLSSGMQKIVAIAR
LIACQSDLWLLDEVETNLSKENRALLNNLIVMKANSGGIVLLSSHLESSIKSAQILRLD
>Mature_218_residues
TTISSKIISILNCFYMDTVVKLRYNKDMLSLHQLQFKNLFDLNITFLPSSITYIKGANGCGKSSLLRMIAGIMQPSSGHI
YYRNCNINNIAKLYCTYIGHNLGLKSEMTVFENLKFWSEIYNSAATLYAAIHYFKLHDLLDKKCYSLSSGMQKIVAIARL
IACQSDLWLLDEVETNLSKENRALLNNLIVMKANSGGIVLLSSHLESSIKSAQILRLD

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system [H]

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI87082064, Length=185, Percent_Identity=30.2702702702703, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI87081791, Length=153, Percent_Identity=32.0261437908497, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1787370, Length=124, Percent_Identity=33.8709677419355, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790467, Length=147, Percent_Identity=30.6122448979592, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1788761, Length=163, Percent_Identity=28.2208588957055, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786698, Length=205, Percent_Identity=25.8536585365854, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081782, Length=183, Percent_Identity=25.1366120218579, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR005895
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.41 [H]

Molecular weight: Translated: 24721; Mature: 24590

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTISSKIISILNCFYMDTVVKLRYNKDMLSLHQLQFKNLFDLNITFLPSSITYIKGANG
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCEEEEEEEEECCCEEEEECCCC
CGKSSLLRMIAGIMQPSSGHIYYRNCNINNIAKLYCTYIGHNLGLKSEMTVFENLKFWSE
CCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
IYNSAATLYAAIHYFKLHDLLDKKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHCCCH
ENRALLNNLIVMKANSGGIVLLSSHLESSIKSAQILRLD
HHHHHHHCEEEEEECCCCEEEEHHHHHHHHCCCEEEECC
>Mature Secondary Structure 
TTISSKIISILNCFYMDTVVKLRYNKDMLSLHQLQFKNLFDLNITFLPSSITYIKGANG
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCEEEEEEEEECCCEEEEECCCC
CGKSSLLRMIAGIMQPSSGHIYYRNCNINNIAKLYCTYIGHNLGLKSEMTVFENLKFWSE
CCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
IYNSAATLYAAIHYFKLHDLLDKKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHCCCH
ENRALLNNLIVMKANSGGIVLLSSHLESSIKSAQILRLD
HHHHHHHCEEEEEECCCCEEEEHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]