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The map label for this gene is fabD [H]

Identifier: 229587090

GI number: 229587090

Start: 1048321

End: 1049265

Strand: Direct

Name: fabD [H]

Synonym: RAF_ORF1024

Alternate gene names: 229587090

Gene position: 1048321-1049265 (Clockwise)

Preceding gene: 229587088

Following gene: 229587091

Centisome position: 81.99

GC content: 35.24

Gene sequence:

>945_bases
ATGAAAACAGCTTTTATCTTCCCCGGTCAAGGGTTGCAATTGATCGGCATGGGGAAAGATTTTTATGATAATTTTAAACC
CGCCAAAGAAACTTTTCAAATCGTTGATGAAGTACTAAACCGAAAACTCACTGATATAATTTTTAATGGACCTTCTGAAG
AACTTACCTTAACCACTAACGCACAACCGGCATTAATGGCAGTATCTATGGCAATAATAAATATTATCAAAGCTGAAACC
GGTAAAAGTTTGGATAGTCTTTGCGATTATGCTGCCGGTCATTCGCTAGGTGAATATAGTGCTTTATGTAGCACCGAAAG
TATTAACCTTGAGACAGCAGCAAAACTACTTCATATACGTAGTACATCTATGCAGGAAGCATGTCCTGAAGGTGAGGGAA
GCATGGCGGCTTGTATCAATATTCCGTTTCAAAAACTTGAAGAAATATTAGAAGAGATCAACAAAATAAATTTATGCCAA
ATCGCCAACGATAACATCGAAGGACAAATAGTTATTAGCGGCAAGACCACAGCTATAGATCATGCTATTAGTATAATTAA
AGATTTAGGTTATAAAGCAATAAAGCTGAAAGTCAGTGCTCCATTTCATTGTAGCTTAATGAAGCCGGCAGAAGAAAAAA
TGCGAGTAGCTCTTGATAAAGCTGTAATTAATAAACCTCTGATACCGATAATCCAAAATTATACCGCAAAACCTACTCTA
GATCCTACAGAAATCAAACAAAATTTAATGCTTCAGATATGCGGGCGAGTTAGATGGCGTGAAACTTTAGAACTATTTCA
CAAATTAGAAATTGCTCATATAGTAGAAATAGGGGCAGGAAGCGTACTAACAAATATGCTCCGGAAAATTAATTATCCAT
ATAAGTTAAGTAATATAAGTAATTTAGAAGAACTACAGCATTGTTTAGATAACATTAGTCAATAA

Upstream 100 bases:

>100_bases
CGTAAAAATTGAAAAACAGTGTTAAAATGCTTAAAATAATTTGACTATTTTAGAAAATTTTAATAAAATCTATTAATAAA
CTCAATCGATAATACAAAAT

Downstream 100 bases:

>100_bases
CTGTCTCTAATAACTTCTGATTCATAAAGTTTTTAAATTAACTTAATATTATTATATGCAAATTAGTTTTAGTTTTTTTA
AGCAATTACTAGAATTATTC

Product: Malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKTAFIFPGQGLQLIGMGKDFYDNFKPAKETFQIVDEVLNRKLTDIIFNGPSEELTLTTNAQPALMAVSMAIINIIKAET
GKSLDSLCDYAAGHSLGEYSALCSTESINLETAAKLLHIRSTSMQEACPEGEGSMAACINIPFQKLEEILEEINKINLCQ
IANDNIEGQIVISGKTTAIDHAISIIKDLGYKAIKLKVSAPFHCSLMKPAEEKMRVALDKAVINKPLIPIIQNYTAKPTL
DPTEIKQNLMLQICGRVRWRETLELFHKLEIAHIVEIGAGSVLTNMLRKINYPYKLSNISNLEELQHCLDNISQ

Sequences:

>Translated_314_residues
MKTAFIFPGQGLQLIGMGKDFYDNFKPAKETFQIVDEVLNRKLTDIIFNGPSEELTLTTNAQPALMAVSMAIINIIKAET
GKSLDSLCDYAAGHSLGEYSALCSTESINLETAAKLLHIRSTSMQEACPEGEGSMAACINIPFQKLEEILEEINKINLCQ
IANDNIEGQIVISGKTTAIDHAISIIKDLGYKAIKLKVSAPFHCSLMKPAEEKMRVALDKAVINKPLIPIIQNYTAKPTL
DPTEIKQNLMLQICGRVRWRETLELFHKLEIAHIVEIGAGSVLTNMLRKINYPYKLSNISNLEELQHCLDNISQ
>Mature_314_residues
MKTAFIFPGQGLQLIGMGKDFYDNFKPAKETFQIVDEVLNRKLTDIIFNGPSEELTLTTNAQPALMAVSMAIINIIKAET
GKSLDSLCDYAAGHSLGEYSALCSTESINLETAAKLLHIRSTSMQEACPEGEGSMAACINIPFQKLEEILEEINKINLCQ
IANDNIEGQIVISGKTTAIDHAISIIKDLGYKAIKLKVSAPFHCSLMKPAEEKMRVALDKAVINKPLIPIIQNYTAKPTL
DPTEIKQNLMLQICGRVRWRETLELFHKLEIAHIVEIGAGSVLTNMLRKINYPYKLSNISNLEELQHCLDNISQ

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=320, Percent_Identity=27.5, Blast_Score=116, Evalue=2e-26,
Organism=Escherichia coli, GI1787334, Length=288, Percent_Identity=36.4583333333333, Blast_Score=182, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI71984332, Length=296, Percent_Identity=27.7027027027027, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=324, Percent_Identity=23.7654320987654, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24665753, Length=302, Percent_Identity=32.1192052980132, Blast_Score=145, Evalue=4e-35,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34803; Mature: 34803

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAFIFPGQGLQLIGMGKDFYDNFKPAKETFQIVDEVLNRKLTDIIFNGPSEELTLTTN
CCCEEEECCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCEEEECC
AQPALMAVSMAIINIIKAETGKSLDSLCDYAAGHSLGEYSALCSTESINLETAAKLLHIR
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHH
STSMQEACPEGEGSMAACINIPFQKLEEILEEINKINLCQIANDNIEGQIVISGKTTAID
CCCHHHHCCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCHHHH
HAISIIKDLGYKAIKLKVSAPFHCSLMKPAEEKMRVALDKAVINKPLIPIIQNYTAKPTL
HHHHHHHHCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCC
DPTEIKQNLMLQICGRVRWRETLELFHKLEIAHIVEIGAGSVLTNMLRKINYPYKLSNIS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCC
NLEELQHCLDNISQ
CHHHHHHHHHHHCC
>Mature Secondary Structure
MKTAFIFPGQGLQLIGMGKDFYDNFKPAKETFQIVDEVLNRKLTDIIFNGPSEELTLTTN
CCCEEEECCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCEEEECC
AQPALMAVSMAIINIIKAETGKSLDSLCDYAAGHSLGEYSALCSTESINLETAAKLLHIR
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHH
STSMQEACPEGEGSMAACINIPFQKLEEILEEINKINLCQIANDNIEGQIVISGKTTAID
CCCHHHHCCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCHHHH
HAISIIKDLGYKAIKLKVSAPFHCSLMKPAEEKMRVALDKAVINKPLIPIIQNYTAKPTL
HHHHHHHHCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCC
DPTEIKQNLMLQICGRVRWRETLELFHKLEIAHIVEIGAGSVLTNMLRKINYPYKLSNIS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCC
NLEELQHCLDNISQ
CHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]