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The map label for this gene is ccmE

Identifier: 229586927

GI number: 229586927

Start: 851130

End: 851516

Strand: Direct

Name: ccmE

Synonym: RAF_ORF0813

Alternate gene names: 229586927

Gene position: 851130-851516 (Clockwise)

Preceding gene: 229586926

Following gene: 229586928

Centisome position: 66.57

GC content: 31.27

Gene sequence:

>387_bases
ATGCAAAAGAGAGTAAGAAATAGATTAATAACAATAATTATTTGTTTTTGCTCAGCATGTTTAGGAATTAGTATAATACT
TTACAATTTAGAGAAAAATATAGTATTTTTTTTGCCGCCGTCAAAAATTAATGAAATAGAACAAGGCAAAGAGTTAAGAG
TCGGTGGGCTGGTTAAAACAGACTCAATAAATAAAATTGCTGATGATAAGATAAGTTTTGTTATTACCGATAATATTAAG
GATTTCGAGATATTATATCAAGGAACCCTTCCGACTCTATTTCGTAAAGGACAAGGAATTATTGCCATCGGACAATTATC
GAACGGGAAATTTATAGCAAGACAATTACTTGCAAAGCATGATGAGAATTACAGGCCTCCGCAATAA

Upstream 100 bases:

>100_bases
TATATATCGGTAGCGTATTTATTTACCTTTTTAACCTTAGCGACATTGTTAATTGTAAGTTTTTTAAATTACAAGTCATT
GAAAAATAAACAGAACTTTA

Downstream 100 bases:

>100_bases
CAACGTCATTGCGAAGAGCGAAGCGACGTGGCAATCTAGTAAAATAGGCCTGAGATTGCTTCGTCGAATTACGTTGTAAT
TCTCCTCGCAATGACAAAAA

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MQKRVRNRLITIIICFCSACLGISIILYNLEKNIVFFLPPSKINEIEQGKELRVGGLVKTDSINKIADDKISFVITDNIK
DFEILYQGTLPTLFRKGQGIIAIGQLSNGKFIARQLLAKHDENYRPPQ

Sequences:

>Translated_128_residues
MQKRVRNRLITIIICFCSACLGISIILYNLEKNIVFFLPPSKINEIEQGKELRVGGLVKTDSINKIADDKISFVITDNIK
DFEILYQGTLPTLFRKGQGIIAIGQLSNGKFIARQLLAKHDENYRPPQ
>Mature_128_residues
MQKRVRNRLITIIICFCSACLGISIILYNLEKNIVFFLPPSKINEIEQGKELRVGGLVKTDSINKIADDKISFVITDNIK
DFEILYQGTLPTLFRKGQGIIAIGQLSNGKFIARQLLAKHDENYRPPQ

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family

Homologues:

Organism=Escherichia coli, GI1788525, Length=138, Percent_Identity=39.1304347826087, Blast_Score=97, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCME_RICAE (C3PP25)

Other databases:

- EMBL:   CP001612
- RefSeq:   YP_002845428.1
- ProteinModelPortal:   C3PP25
- GeneID:   7815620
- GenomeReviews:   CP001612_GR
- KEGG:   raf:RAF_ORF0813
- OMA:   ICFCSAC
- ProtClustDB:   PRK13254
- HAMAP:   MF_01959
- InterPro:   IPR004329
- InterPro:   IPR012340
- Gene3D:   G3DSA:2.40.50.140

Pfam domain/function: PF03100 CcmE; SSF82093 Pyrv/PenolPyrv_Kinase_cat

EC number: NA

Molecular weight: Translated: 14506; Mature: 14506

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: BINDING 120-120

Signals:

None

Transmembrane regions:

HASH(0x219caf68)-;

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRVRNRLITIIICFCSACLGISIILYNLEKNIVFFLPPSKINEIEQGKELRVGGLVKT
CCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCHHHHHHHCCCEEEECCEEEC
DSINKIADDKISFVITDNIKDFEILYQGTLPTLFRKGQGIIAIGQLSNGKFIARQLLAKH
CCCCCCCCCCEEEEEECCCCCEEEEEECCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHC
DENYRPPQ
CCCCCCCH
>Mature Secondary Structure
MQKRVRNRLITIIICFCSACLGISIILYNLEKNIVFFLPPSKINEIEQGKELRVGGLVKT
CCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCHHHHHHHCCCEEEECCEEEC
DSINKIADDKISFVITDNIKDFEILYQGTLPTLFRKGQGIIAIGQLSNGKFIARQLLAKH
CCCCCCCCCCEEEEEECCCCCEEEEEECCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHC
DENYRPPQ
CCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA