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The map label for this gene is atrC1 [H]

Identifier: 229586564

GI number: 229586564

Start: 412450

End: 413847

Strand: Direct

Name: atrC1 [H]

Synonym: RAF_ORF0385

Alternate gene names: 229586564

Gene position: 412450-413847 (Clockwise)

Preceding gene: 229586563

Following gene: 229586565

Centisome position: 32.26

GC content: 35.98

Gene sequence:

>1398_bases
ATGAGTTTTTTAAGGAAGAAAAGTTTTGAATCAGTAAAAGAGATAGGCAGTTCAAGCGGTCTTAGCAAGACACTTGGAGC
ATTCGATTTAATATTACTGGGTCTTGGTGCGATGATCGGCACAGGTGTATTCGTCGTTACCGGTATAATTGCTGCTAAAT
ATTCAGGACCTGCGGTAATGTTATCTTATGTGATTGCAGGTATTACCTGTATCTTTGTAGCGCTTGTTTATACTGAACTT
GCTGCAATGCTTCCGACATCAGGCAGTATTTACACTTATTCCTATGTAGCATTTGGCGAAGTATTTGCTTGGATGATCGG
TAGTGTTATAATATTAGAACTTGGTGTTGCTGCAGGAATAGTAGCTGCAGGCTGGTCGGGCTACGTACAAGGAATACTAG
CAGCAGGTGGAATCAATTTACCGAAAGAATTAACTACTGTACCGACAAACGGCGGTATAATAAATTTACCGGCATTTTTA
ATCTCGGGATTTATTGGATTTATTTTATATTTAGGTACTAAAGATAGTAAGAGACTAAATGCAATTTTAGTTTTCATAAA
AATGACTGCAATATTTGTATTTATACTCGCTGCTGCCCCTCATTTTGATGCTACTAACTGGAGTAATTTTATGCCTTTCG
GTTTTAGTAATGTTTTAGTAGGTGCGTCTATTTTATTCTTAGCTTTTACGGGTTTTGGAACGATTGCAACCGCAGCTGAG
GAGTGTAAAAACCCAAAACGCGATATAATGATCGGTATTATTGGCTCACTTGTTCTAACTACTATAGTTTATGTAACAAT
GGCAGGGCTTGTGACCGGTATTGCACCTTTTGATCAGTTAAATAACGATCAACCGCTTGCTTATGCTTTAACTATCAATA
ATAGCAAGATCGGCTCTGCTATTGTTGCAACCGGAGCAGTTTGCGGTATGATGACGGTGTTGATGATGAATATTTACGGT
ACTTCTCGTATTTTTTATGCTATTGCACGTGACGGTTTACTACCGAAAAGTTTTGCAAAGCTGCACCCAAAATATGATAG
TCCGTATATTACGATTATAATATTTGCTTCTTTAGCCGCTATCCTTGGAGGATTTTGTTCTACGGAATTATTAACGCAAT
TAACTTCAATGGGAGCTCTTATTGATTATATAACCGTTACAATAATAGTGGTATTATTTAGGGTCACGCTACCTGATGCT
CAAAGACCTTTTAGATGTCCTTTAGTATTTATTATCGTACCGTTTATTTTAATTGCTTGTGCATATTTACTATTTATTCA
AATATATGACGGTGAATTTAATCTATTAACCGCAGGTCGTGCATTAATATATTGGTTTATTACAATATTTGTTTTATATA
TTATAAGATCGTTTTTTATGCAAAAAGAGCAGAATTAA

Upstream 100 bases:

>100_bases
GCAATCTAGTTAGACCTTCTGAGATTGCCACGCTCCTTTTAGTCGCTCGCAATGAGACACAATTCACAAAAAAATAAGCT
CACTAAAACAGGAGAAACTA

Downstream 100 bases:

>100_bases
GAGGGGGATATCCGTCATTGCGAGCGAACGTAGAGAGCATGGCAATCTCATGAAGTAGTACAAAATTCCTGAGATTGCCA
AGTCAAGGCTTTGCCTCTCC

Product: Cationic amino acid transporter-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSFLRKKSFESVKEIGSSSGLSKTLGAFDLILLGLGAMIGTGVFVVTGIIAAKYSGPAVMLSYVIAGITCIFVALVYTEL
AAMLPTSGSIYTYSYVAFGEVFAWMIGSVIILELGVAAGIVAAGWSGYVQGILAAGGINLPKELTTVPTNGGIINLPAFL
ISGFIGFILYLGTKDSKRLNAILVFIKMTAIFVFILAAAPHFDATNWSNFMPFGFSNVLVGASILFLAFTGFGTIATAAE
ECKNPKRDIMIGIIGSLVLTTIVYVTMAGLVTGIAPFDQLNNDQPLAYALTINNSKIGSAIVATGAVCGMMTVLMMNIYG
TSRIFYAIARDGLLPKSFAKLHPKYDSPYITIIIFASLAAILGGFCSTELLTQLTSMGALIDYITVTIIVVLFRVTLPDA
QRPFRCPLVFIIVPFILIACAYLLFIQIYDGEFNLLTAGRALIYWFITIFVLYIIRSFFMQKEQN

Sequences:

>Translated_465_residues
MSFLRKKSFESVKEIGSSSGLSKTLGAFDLILLGLGAMIGTGVFVVTGIIAAKYSGPAVMLSYVIAGITCIFVALVYTEL
AAMLPTSGSIYTYSYVAFGEVFAWMIGSVIILELGVAAGIVAAGWSGYVQGILAAGGINLPKELTTVPTNGGIINLPAFL
ISGFIGFILYLGTKDSKRLNAILVFIKMTAIFVFILAAAPHFDATNWSNFMPFGFSNVLVGASILFLAFTGFGTIATAAE
ECKNPKRDIMIGIIGSLVLTTIVYVTMAGLVTGIAPFDQLNNDQPLAYALTINNSKIGSAIVATGAVCGMMTVLMMNIYG
TSRIFYAIARDGLLPKSFAKLHPKYDSPYITIIIFASLAAILGGFCSTELLTQLTSMGALIDYITVTIIVVLFRVTLPDA
QRPFRCPLVFIIVPFILIACAYLLFIQIYDGEFNLLTAGRALIYWFITIFVLYIIRSFFMQKEQN
>Mature_464_residues
SFLRKKSFESVKEIGSSSGLSKTLGAFDLILLGLGAMIGTGVFVVTGIIAAKYSGPAVMLSYVIAGITCIFVALVYTELA
AMLPTSGSIYTYSYVAFGEVFAWMIGSVIILELGVAAGIVAAGWSGYVQGILAAGGINLPKELTTVPTNGGIINLPAFLI
SGFIGFILYLGTKDSKRLNAILVFIKMTAIFVFILAAAPHFDATNWSNFMPFGFSNVLVGASILFLAFTGFGTIATAAEE
CKNPKRDIMIGIIGSLVLTTIVYVTMAGLVTGIAPFDQLNNDQPLAYALTINNSKIGSAIVATGAVCGMMTVLMMNIYGT
SRIFYAIARDGLLPKSFAKLHPKYDSPYITIIIFASLAAILGGFCSTELLTQLTSMGALIDYITVTIIVVLFRVTLPDAQ
RPFRCPLVFIIVPFILIACAYLLFIQIYDGEFNLLTAGRALIYWFITIFVLYIIRSFFMQKEQN

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI110347453, Length=402, Percent_Identity=33.5820895522388, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI4507047, Length=424, Percent_Identity=30.188679245283, Blast_Score=185, Evalue=8e-47,
Organism=Homo sapiens, GI181337167, Length=415, Percent_Identity=33.7349397590361, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI258614005, Length=426, Percent_Identity=28.6384976525822, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI258614003, Length=426, Percent_Identity=28.6384976525822, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI114326544, Length=437, Percent_Identity=27.6887871853547, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI114326550, Length=437, Percent_Identity=27.6887871853547, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI258645169, Length=426, Percent_Identity=28.169014084507, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI7657683, Length=389, Percent_Identity=24.4215938303342, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI115648063, Length=466, Percent_Identity=23.6051502145923, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI115648022, Length=466, Percent_Identity=23.6051502145923, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI87082250, Length=362, Percent_Identity=26.2430939226519, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788480, Length=419, Percent_Identity=25.7756563245823, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87082023, Length=401, Percent_Identity=25.9351620947631, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786694, Length=450, Percent_Identity=23.7777777777778, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789017, Length=360, Percent_Identity=23.6111111111111, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87081915, Length=362, Percent_Identity=25.1381215469613, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786302, Length=418, Percent_Identity=22.2488038277512, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=413, Percent_Identity=32.6876513317191, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17533459, Length=415, Percent_Identity=30.1204819277108, Blast_Score=191, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI17531343, Length=409, Percent_Identity=31.0513447432763, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17568033, Length=437, Percent_Identity=25.858123569794, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537453, Length=414, Percent_Identity=22.9468599033816, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540018, Length=212, Percent_Identity=30.188679245283, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221512776, Length=416, Percent_Identity=31.9711538461538, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24666159, Length=416, Percent_Identity=31.9711538461538, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24667468, Length=381, Percent_Identity=33.0708661417323, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24668806, Length=427, Percent_Identity=31.8501170960187, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI21356285, Length=427, Percent_Identity=31.8501170960187, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24668802, Length=427, Percent_Identity=31.8501170960187, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI161077963, Length=405, Percent_Identity=32.0987654320988, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI281366235, Length=410, Percent_Identity=30, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI116007820, Length=410, Percent_Identity=30, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI116007818, Length=411, Percent_Identity=30.1703163017032, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI85725152, Length=411, Percent_Identity=30.1703163017032, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI21357367, Length=444, Percent_Identity=24.3243243243243, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50008; Mature: 49877

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SFLRKKSFESVKEIGSSSGLSKTLGAFDLILLGLGAMIGTGVFVVTGIIAAKYSGPAVM
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LSYVIAGITCIFVALVYTELAAMLPTSGSIYTYSYVAFGEVFAWMIGSVIILELGVAAGI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAGWSGYVQGILAAGGINLPKELTTVPTNGGIINLPAFLISGFIGFILYLGTKDSKRLN
HHHCHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHH
AILVFIKMTAIFVFILAAAPHFDATNWSNFMPFGFSNVLVGASILFLAFTGFGTIATAAE
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
ECKNPKRDIMIGIIGSLVLTTIVYVTMAGLVTGIAPFDQLNNDQPLAYALTINNSKIGSA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEEEECCCCCCHH
IVATGAVCGMMTVLMMNIYGTSRIFYAIARDGLLPKSFAKLHPKYDSPYITIIIFASLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHH
ILGGFCSTELLTQLTSMGALIDYITVTIIVVLFRVTLPDAQRPFRCPLVFIIVPFILIAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
AYLLFIQIYDGEFNLLTAGRALIYWFITIFVLYIIRSFFMQKEQN
HHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]