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The map label for this gene is gppA [C]

Identifier: 229586545

GI number: 229586545

Start: 394170

End: 395582

Strand: Direct

Name: gppA [C]

Synonym: RAF_ORF0366

Alternate gene names: 229586545

Gene position: 394170-395582 (Clockwise)

Preceding gene: 229586544

Following gene: 229586549

Centisome position: 30.83

GC content: 29.51

Gene sequence:

>1413_bases
ATGCGTTCAGCTATTATTGATATCGGTTCAAATGCTTTAAGAGCTGTAGTTTATGAAAGTGATGAGCTTGGAGCGCCGGA
AATTTTTAATTATAAATTTAGAAATTATCTTACAAATTTACTTAATTTAGATAATTTAGACGTAAAACATCAAACATATT
TATCTCTACAATATCTTATTCATATTTTTACCAAACTGTCTGTTACTAATATTAGATGTGTTGCAACAGCTATACTTAGG
GGGCATCCTAAAGCAGATGAATTCAAAGCTATAATTAAAAAGAGATTCAATATTGATATTGAAATTATCTCAGGTGAACG
TGAAGCTTATTTAACTGCTGCCGGATTAATTTCCGGTATTAGTGATGCTTTCGGTATTGTAGCTGATCTTGGAGGTGGAA
GTCTTGAGCTTGCACAGATTGGAAATAAAAAAGTCGGTAAATTAAAATCATTGCCGCTTGGTACAAAAATTATTGTTAGT
AGCAATTTTGGTGATGTCGGGCTGATTACTAAAATGCTAGAGGAAGAATTTGGAGCTGCACATTATCCTAATTTATATTT
AATTGGCGGTGCATTACGTCTAATGAGCCGTATATACATGGAGTCTATAAATTATCCCCTTAAAAATTTACATAATTTTG
AAATAAATCGTGTAGAGTTTGAGTTATATTTAGAGAAATTATCGCAAATCGATAAATTAAAGCTGAGTTATTATGAGCAG
AAAGTCATAAATTATAATGCAGTTTTAGTAATAAAAGCAATGATTAAGGTATTTTCACCGGAAAAAATTATTATCTCAAA
TTACGGTTTAAAAGAAGGAGTAAGATTTGACTCGTTGCCGTCTCATGAAACAGAAAAAGATATTATTTATGAGAGGGTGA
AGAGATTAGTAAAATTTGATAGAAATATATGTAAAATTGAAAAATATATTGAAGCAGTACAATATCTTTTAATTAATGCC
GATGCCACGACTCTTATTGTTATTGAACTCGCTATAATGCTAGCACAATATAATAAAAATATTGATAAAACGCTTAGAGC
AAATTTTGTTTCGGAATTTATATTATCTTCAGACATTCCTTTTAGTCATAGACAGCGTCTTATGCTAGGTATTGCCCTTA
CAGTTACTTATACTGCTAAAACTGACATGCAGATTAATAAAATAGCTAAGAAAATGATTAGTAAAAGTGATTATTATAAC
AGTCATATAATCGGTTATTATATAAAAATTGCTAGAGAAATTGATGGGCCAGAATTTCAAGAGCCTTCTTTTTCGATTAA
ATTAAAAGACGATAAATTTTTACAAATTAATGCTTCAAATATCTTGCCTAAACAAGTCTTTGAAAAGGTTTGTGAACGTT
TAAAAGATATAAGTTCTGCTAGAAAAAATATTAGGTATAATTTTAGTGATTAG

Upstream 100 bases:

>100_bases
ACTTTTGTACCTACTCAAGTACCTTTTGACCCTAGGGCAAATAATAATGGGGCTTCGGAAGAGACCGAAACAATAACTGT
TCCGGAAAATAATGAGTAAA

Downstream 100 bases:

>100_bases
GGTTTTTTTGTTATAGTGCCGGATAGTTTTCAAAAAGCCAGTGATGTCATACCTGCGAAAGCAGGGATACAGGCTAAAAA
AATCTTGATTGCAAAGATTT

Product: Guanosine pentaphosphate phosphohydrolase

Products: (polyphosphate)n-1; phosphate

Alternate protein names: Exopolyphosphatase; Phosphatase Ppx/GppA Family; Guanosine Pentaphosphate Phosphohydrolase; Ppx/GppA Family Phosphatase; Ppx/Gppa Phosphatase; Ppx/GppA Phosphatase Family; Phosphatase; Guanosine Pentaphosphate Phosphohydrolase Gppa; Ppx/GppA Phosphatase Family Protein; Guanosine-5-Triphosphate 3'-Diphosphate Pyrophosphatase; Ppx-GppA Ppx/GppA Phosphatase Family Protein; Exopolyphosphatase Protein; Ppx/GppA Family Phosphotase; Guanosine Pentaphosphate Phosphohydrolase GPPA; Nucleoside Diphosphate Kinase; Exopolyphosphatase Homolog; Exopolyphosphatase Ppx; Guanosine Pentaphosphate Phosphohydrolase Phage Proteinpa; Fumarate Reductase

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MRSAIIDIGSNALRAVVYESDELGAPEIFNYKFRNYLTNLLNLDNLDVKHQTYLSLQYLIHIFTKLSVTNIRCVATAILR
GHPKADEFKAIIKKRFNIDIEIISGEREAYLTAAGLISGISDAFGIVADLGGGSLELAQIGNKKVGKLKSLPLGTKIIVS
SNFGDVGLITKMLEEEFGAAHYPNLYLIGGALRLMSRIYMESINYPLKNLHNFEINRVEFELYLEKLSQIDKLKLSYYEQ
KVINYNAVLVIKAMIKVFSPEKIIISNYGLKEGVRFDSLPSHETEKDIIYERVKRLVKFDRNICKIEKYIEAVQYLLINA
DATTLIVIELAIMLAQYNKNIDKTLRANFVSEFILSSDIPFSHRQRLMLGIALTVTYTAKTDMQINKIAKKMISKSDYYN
SHIIGYYIKIAREIDGPEFQEPSFSIKLKDDKFLQINASNILPKQVFEKVCERLKDISSARKNIRYNFSD

Sequences:

>Translated_470_residues
MRSAIIDIGSNALRAVVYESDELGAPEIFNYKFRNYLTNLLNLDNLDVKHQTYLSLQYLIHIFTKLSVTNIRCVATAILR
GHPKADEFKAIIKKRFNIDIEIISGEREAYLTAAGLISGISDAFGIVADLGGGSLELAQIGNKKVGKLKSLPLGTKIIVS
SNFGDVGLITKMLEEEFGAAHYPNLYLIGGALRLMSRIYMESINYPLKNLHNFEINRVEFELYLEKLSQIDKLKLSYYEQ
KVINYNAVLVIKAMIKVFSPEKIIISNYGLKEGVRFDSLPSHETEKDIIYERVKRLVKFDRNICKIEKYIEAVQYLLINA
DATTLIVIELAIMLAQYNKNIDKTLRANFVSEFILSSDIPFSHRQRLMLGIALTVTYTAKTDMQINKIAKKMISKSDYYN
SHIIGYYIKIAREIDGPEFQEPSFSIKLKDDKFLQINASNILPKQVFEKVCERLKDISSARKNIRYNFSD
>Mature_470_residues
MRSAIIDIGSNALRAVVYESDELGAPEIFNYKFRNYLTNLLNLDNLDVKHQTYLSLQYLIHIFTKLSVTNIRCVATAILR
GHPKADEFKAIIKKRFNIDIEIISGEREAYLTAAGLISGISDAFGIVADLGGGSLELAQIGNKKVGKLKSLPLGTKIIVS
SNFGDVGLITKMLEEEFGAAHYPNLYLIGGALRLMSRIYMESINYPLKNLHNFEINRVEFELYLEKLSQIDKLKLSYYEQ
KVINYNAVLVIKAMIKVFSPEKIIISNYGLKEGVRFDSLPSHETEKDIIYERVKRLVKFDRNICKIEKYIEAVQYLLINA
DATTLIVIELAIMLAQYNKNIDKTLRANFVSEFILSSDIPFSHRQRLMLGIALTVTYTAKTDMQINKIAKKMISKSDYYN
SHIIGYYIKIAREIDGPEFQEPSFSIKLKDDKFLQINASNILPKQVFEKVCERLKDISSARKNIRYNFSD

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.11; 3.6.1.40

Molecular weight: Translated: 53625; Mature: 53625

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSAIIDIGSNALRAVVYESDELGAPEIFNYKFRNYLTNLLNLDNLDVKHQTYLSLQYLI
CCCEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
HIFTKLSVTNIRCVATAILRGHPKADEFKAIIKKRFNIDIEIISGEREAYLTAAGLISGI
HHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
SDAFGIVADLGGGSLELAQIGNKKVGKLKSLPLGTKIIVSSNFGDVGLITKMLEEEFGAA
HHHHHHHHCCCCCCEEHHHCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCC
HYPNLYLIGGALRLMSRIYMESINYPLKNLHNFEINRVEFELYLEKLSQIDKLKLSYYEQ
CCCCEEEEHHHHHHHHHHHHHHCCCCHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
KVINYNAVLVIKAMIKVFSPEKIIISNYGLKEGVRFDSLPSHETEKDIIYERVKRLVKFD
HHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
RNICKIEKYIEAVQYLLINADATTLIVIELAIMLAQYNKNIDKTLRANFVSEFILSSDIP
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
FSHRQRLMLGIALTVTYTAKTDMQINKIAKKMISKSDYYNSHIIGYYIKIAREIDGPEFQ
HHHHHHHHEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHEEEHHHCCCCCCC
EPSFSIKLKDDKFLQINASNILPKQVFEKVCERLKDISSARKNIRYNFSD
CCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRSAIIDIGSNALRAVVYESDELGAPEIFNYKFRNYLTNLLNLDNLDVKHQTYLSLQYLI
CCCEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
HIFTKLSVTNIRCVATAILRGHPKADEFKAIIKKRFNIDIEIISGEREAYLTAAGLISGI
HHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
SDAFGIVADLGGGSLELAQIGNKKVGKLKSLPLGTKIIVSSNFGDVGLITKMLEEEFGAA
HHHHHHHHCCCCCCEEHHHCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCC
HYPNLYLIGGALRLMSRIYMESINYPLKNLHNFEINRVEFELYLEKLSQIDKLKLSYYEQ
CCCCEEEEHHHHHHHHHHHHHHCCCCHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
KVINYNAVLVIKAMIKVFSPEKIIISNYGLKEGVRFDSLPSHETEKDIIYERVKRLVKFD
HHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
RNICKIEKYIEAVQYLLINADATTLIVIELAIMLAQYNKNIDKTLRANFVSEFILSSDIP
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
FSHRQRLMLGIALTVTYTAKTDMQINKIAKKMISKSDYYNSHIIGYYIKIAREIDGPEFQ
HHHHHHHHEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHEEEHHHCCCCCCC
EPSFSIKLKDDKFLQINASNILPKQVFEKVCERLKDISSARKNIRYNFSD
CCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (polyphosphate)n; H2O

Specific reaction: (polyphosphate)n + H2O = (polyphosphate)n-1 + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA