Click here to switch to the map view.

The map label for this gene is murB [H]

Identifier: 229586497

GI number: 229586497

Start: 335712

End: 336635

Strand: Direct

Name: murB [H]

Synonym: RAF_ORF0309

Alternate gene names: 229586497

Gene position: 335712-336635 (Clockwise)

Preceding gene: 229586496

Following gene: 229586498

Centisome position: 26.26

GC content: 34.09

Gene sequence:

>924_bases
GTGAAGATAACAGTAAAGCGAATAGCAGGACTAAATATGTTAATTTTACCGATAGTAAAAGGCGAGTATAAAAAAGATTA
TAATTTAAAACACTTAACATGGTTTAAAGTAGGCGGTAATGCTGAAATTTTCTTTAAACCTTTAGATAGCGAAGATTTAA
AAAGTTTCTTAATACAAAATAAGCAAAAATTACCTATAAAGACTTTTGGAGCAGGCTCAAATGTTATTATAAGAGACGGT
GGCATAGAAGGGGTCGTTATAAAACTTGGTCAGAATTTTAGCAATATTGAGTTTATAGATAATCATTTAATAGTAGGTAG
TAGCTGCCTTAATTATAATTTAGCAAAATTTTGTCAAGCAAATGCTATTTCCGGTTTTGAGTTTTTAGTAGGTATTCCAG
GGACTATCGGCGGCGGTGTTGCTATGAATGCCGGTGCTTACGGCTCTGAATTTAAAGATATTGTAGTGCAGATTGAAGCG
ATTGACTTTGCAGGAAACTTTTTAACATTCACAAATGAAGAAATCGGTTTTAAATATCGCAGTAATAATTTACCAAAGAA
TTTAATTATTCTCAAAGCTGTTTTTAAAATAAATAAAGGCGATAGTGAAAATATATTATTACGGATGAATGAAATACATA
ACGCAAGATCATCTACACAGCCTATTAAAGAGCGTACGGGCGGTAGTACTTTTGCAAATCCTGAAGGGCGTAAATCTTGG
GAACTTATTGACAAAGCGGGGCTTAGAGGTTATAGAATAGGCGGTGCTTCGATGTCAGAACTTCATTGTAATTTTATGAT
AAATAATGGTGATGCTACCGCTAAGGATTTAGAAGATTTAGGTGATTTTGTTCGGCAGAAAGTATGTGAAGATAGCGGGG
TTAAGTTAGAGTGGGAGATTAAGAGAATCGGACGTCATCCCTAA

Upstream 100 bases:

>100_bases
TTTGACTGGTATTGTTGCATAGCTCTTATGTCATTCCCGCGAAAGCGGGAATGACATCTGTTCGTATAACATAGGGTCAA
GCGAACTAAGGGACAAAAGA

Downstream 100 bases:

>100_bases
TTAAAAATGGCGTTGTTGCAGCTAGTTTTATGTCATTCCCGCGAAGGCGGGAATCCAGTAAAACATATAAAAAACAAGTT
TTTTATATGTTTATTTTATA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MKITVKRIAGLNMLILPIVKGEYKKDYNLKHLTWFKVGGNAEIFFKPLDSEDLKSFLIQNKQKLPIKTFGAGSNVIIRDG
GIEGVVIKLGQNFSNIEFIDNHLIVGSSCLNYNLAKFCQANAISGFEFLVGIPGTIGGGVAMNAGAYGSEFKDIVVQIEA
IDFAGNFLTFTNEEIGFKYRSNNLPKNLIILKAVFKINKGDSENILLRMNEIHNARSSTQPIKERTGGSTFANPEGRKSW
ELIDKAGLRGYRIGGASMSELHCNFMINNGDATAKDLEDLGDFVRQKVCEDSGVKLEWEIKRIGRHP

Sequences:

>Translated_307_residues
MKITVKRIAGLNMLILPIVKGEYKKDYNLKHLTWFKVGGNAEIFFKPLDSEDLKSFLIQNKQKLPIKTFGAGSNVIIRDG
GIEGVVIKLGQNFSNIEFIDNHLIVGSSCLNYNLAKFCQANAISGFEFLVGIPGTIGGGVAMNAGAYGSEFKDIVVQIEA
IDFAGNFLTFTNEEIGFKYRSNNLPKNLIILKAVFKINKGDSENILLRMNEIHNARSSTQPIKERTGGSTFANPEGRKSW
ELIDKAGLRGYRIGGASMSELHCNFMINNGDATAKDLEDLGDFVRQKVCEDSGVKLEWEIKRIGRHP
>Mature_307_residues
MKITVKRIAGLNMLILPIVKGEYKKDYNLKHLTWFKVGGNAEIFFKPLDSEDLKSFLIQNKQKLPIKTFGAGSNVIIRDG
GIEGVVIKLGQNFSNIEFIDNHLIVGSSCLNYNLAKFCQANAISGFEFLVGIPGTIGGGVAMNAGAYGSEFKDIVVQIEA
IDFAGNFLTFTNEEIGFKYRSNNLPKNLIILKAVFKINKGDSENILLRMNEIHNARSSTQPIKERTGGSTFANPEGRKSW
ELIDKAGLRGYRIGGASMSELHCNFMINNGDATAKDLEDLGDFVRQKVCEDSGVKLEWEIKRIGRHP

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 33997; Mature: 33997

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITVKRIAGLNMLILPIVKGEYKKDYNLKHLTWFKVGGNAEIFFKPLDSEDLKSFLIQN
CEEEEHHHCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCCEEEEEECCHHHHHHHHHCC
KQKLPIKTFGAGSNVIIRDGGIEGVVIKLGQNFSNIEFIDNHLIVGSSCLNYNLAKFCQA
CCCCCEEEECCCCEEEEECCCCCEEEEEECCCCCCEEEECCEEEECCHHHCCCHHHHHHC
NAISGFEFLVGIPGTIGGGVAMNAGAYGSEFKDIVVQIEAIDFAGNFLTFTNEEIGFKYR
CCCCCEEEEEECCCCCCCCEEECCCCCCCCCEEEEEEEEEEEECCCEEEECCCCCCEEEC
SNNLPKNLIILKAVFKINKGDSENILLRMNEIHNARSSTQPIKERTGGSTFANPEGRKSW
CCCCCCHHEEEEEEEEECCCCCCCEEEEEHHHHCCCCCCCCHHHHCCCCCCCCCCCCCHH
ELIDKAGLRGYRIGGASMSELHCNFMINNGDATAKDLEDLGDFVRQKVCEDSGVKLEWEI
HHHHHCCCCEEEECCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEH
KRIGRHP
HCCCCCC
>Mature Secondary Structure
MKITVKRIAGLNMLILPIVKGEYKKDYNLKHLTWFKVGGNAEIFFKPLDSEDLKSFLIQN
CEEEEHHHCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCCEEEEEECCHHHHHHHHHCC
KQKLPIKTFGAGSNVIIRDGGIEGVVIKLGQNFSNIEFIDNHLIVGSSCLNYNLAKFCQA
CCCCCEEEECCCCEEEEECCCCCEEEEEECCCCCCEEEECCEEEECCHHHCCCHHHHHHC
NAISGFEFLVGIPGTIGGGVAMNAGAYGSEFKDIVVQIEAIDFAGNFLTFTNEEIGFKYR
CCCCCEEEEEECCCCCCCCEEECCCCCCCCCEEEEEEEEEEEECCCEEEECCCCCCEEEC
SNNLPKNLIILKAVFKINKGDSENILLRMNEIHNARSSTQPIKERTGGSTFANPEGRKSW
CCCCCCHHEEEEEEEEECCCCCCCEEEEEHHHHCCCCCCCCHHHHCCCCCCCCCCCCCHH
ELIDKAGLRGYRIGGASMSELHCNFMINNGDATAKDLEDLGDFVRQKVCEDSGVKLEWEI
HHHHHCCCCEEEECCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEH
KRIGRHP
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA