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The map label for this gene is coxC [H]

Identifier: 229586435

GI number: 229586435

Start: 252431

End: 253357

Strand: Direct

Name: coxC [H]

Synonym: RAF_ORF0231

Alternate gene names: 229586435

Gene position: 252431-253357 (Clockwise)

Preceding gene: 229586434

Following gene: 229586436

Centisome position: 19.74

GC content: 32.58

Gene sequence:

>927_bases
ATGCGAATAGCAGATTACTTTTGTAGTTTGTTATTGGTGATAATTAGGAAATATAAAATAACAATATGTAACAATATGAG
TCAAAAGATAATTTTAAATAATTCATATTCTATTACTAAATCGCACTTATTCCATATAGTAGACCCAAGTCCTTGGCCCG
TCCTAACATCTTTTGCTTTACTTCTTTTGGTTATAGGCGGCGTCTCGTTCATGCATGGATACAAATTTAATATATATATT
TTATCTGCAGGGATTATTTCAGTAGGTTACTGTTTATATTCTTGGTGGAGAGATATAGTGAAAGAAGGAATAGTCGAACA
TCAGCATACTAGTCCTGTTAGAAAAGGTTTGCAAATAGGTATGGCGTTATTTATCTTAACGGAAATAGTATTTTTTGGTG
TATTTTTTGCTTCTTTTTTTAAATCAAGTCTATCACCCGTAGGTCTTTTAGATGGTGTATGGGTTGTAAAGCAGGGCATT
TGGCCTCCACCTACAATTAAAACTTTTGAGCCGTTTGATATTCCTTTTATCAATACTTTAATACTACTCTTATCAGGTAC
GACCGTTACTTGGGCTCACTACGCCTTAGAAGAAAAAAATCAAAAAGATTGTGTAACTGCACTTGCTCTTACCATATTGC
TTGGAATATTTTTTACAACTATGCAGGCATATGAATATTACCATGCGGCGTTTAAATTTACAGATGGTATATATGCTTCT
AATTTTTATTTAGCCACGGGTTTTCATGGAGCTCATGTAATTATAGGTACCATATTTCTAATAATTTGCTACTTTAGAGC
AAAAAGAGGAGATTTTACTACAGAAGGTAATGGACATTTAGGGTTTGAATTTGCTGCATGGTACTGGCATTTTGTAGATG
TGGTTTGGTTATTTTTATTTACGTTTGTTTATATATTTGGAAGTTAA

Upstream 100 bases:

>100_bases
TAATAAATAATGTAATTCTGAGTTGGGGGGTATATTTTCTATATAATCTCCTTCTAGCATTTGCTTTTACATCAATAATA
ATTTATATTTATTTTCACTC

Downstream 100 bases:

>100_bases
ATTATACTATATGTGATTATAATGTTACTTAAAATAAGTGTTTTTAAAATATTTTTGCATATTCATTAAAATTGCATATA
TTTAGGAGTTGATTTATATA

Product: Cytochrome c oxidase subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MRIADYFCSLLLVIIRKYKITICNNMSQKIILNNSYSITKSHLFHIVDPSPWPVLTSFALLLLVIGGVSFMHGYKFNIYI
LSAGIISVGYCLYSWWRDIVKEGIVEHQHTSPVRKGLQIGMALFILTEIVFFGVFFASFFKSSLSPVGLLDGVWVVKQGI
WPPPTIKTFEPFDIPFINTLILLLSGTTVTWAHYALEEKNQKDCVTALALTILLGIFFTTMQAYEYYHAAFKFTDGIYAS
NFYLATGFHGAHVIIGTIFLIICYFRAKRGDFTTEGNGHLGFEFAAWYWHFVDVVWLFLFTFVYIFGS

Sequences:

>Translated_308_residues
MRIADYFCSLLLVIIRKYKITICNNMSQKIILNNSYSITKSHLFHIVDPSPWPVLTSFALLLLVIGGVSFMHGYKFNIYI
LSAGIISVGYCLYSWWRDIVKEGIVEHQHTSPVRKGLQIGMALFILTEIVFFGVFFASFFKSSLSPVGLLDGVWVVKQGI
WPPPTIKTFEPFDIPFINTLILLLSGTTVTWAHYALEEKNQKDCVTALALTILLGIFFTTMQAYEYYHAAFKFTDGIYAS
NFYLATGFHGAHVIIGTIFLIICYFRAKRGDFTTEGNGHLGFEFAAWYWHFVDVVWLFLFTFVYIFGS
>Mature_308_residues
MRIADYFCSLLLVIIRKYKITICNNMSQKIILNNSYSITKSHLFHIVDPSPWPVLTSFALLLLVIGGVSFMHGYKFNIYI
LSAGIISVGYCLYSWWRDIVKEGIVEHQHTSPVRKGLQIGMALFILTEIVFFGVFFASFFKSSLSPVGLLDGVWVVKQGI
WPPPTIKTFEPFDIPFINTLILLLSGTTVTWAHYALEEKNQKDCVTALALTILLGIFFTTMQAYEYYHAAFKFTDGIYAS
NFYLATGFHGAHVIIGTIFLIICYFRAKRGDFTTEGNGHLGFEFAAWYWHFVDVVWLFLFTFVYIFGS

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=269, Percent_Identity=46.0966542750929, Blast_Score=234, Evalue=8e-62,
Organism=Escherichia coli, GI1786633, Length=211, Percent_Identity=27.9620853080569, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6226542, Length=268, Percent_Identity=37.6865671641791, Blast_Score=177, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 35150; Mature: 35150

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIADYFCSLLLVIIRKYKITICNNMSQKIILNNSYSITKSHLFHIVDPSPWPVLTSFAL
CCHHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCCEEHHHHEEEEECCCCCHHHHHHHH
LLLVIGGVSFMHGYKFNIYILSAGIISVGYCLYSWWRDIVKEGIVEHQHTSPVRKGLQIG
HHHHHHHHHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MALFILTEIVFFGVFFASFFKSSLSPVGLLDGVWVVKQGIWPPPTIKTFEPFDIPFINTL
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
ILLLSGTTVTWAHYALEEKNQKDCVTALALTILLGIFFTTMQAYEYYHAAFKFTDGIYAS
HHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
NFYLATGFHGAHVIIGTIFLIICYFRAKRGDFTTEGNGHLGFEFAAWYWHFVDVVWLFLF
CEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TFVYIFGS
HHHHHHCC
>Mature Secondary Structure
MRIADYFCSLLLVIIRKYKITICNNMSQKIILNNSYSITKSHLFHIVDPSPWPVLTSFAL
CCHHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCCEEHHHHEEEEECCCCCHHHHHHHH
LLLVIGGVSFMHGYKFNIYILSAGIISVGYCLYSWWRDIVKEGIVEHQHTSPVRKGLQIG
HHHHHHHHHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MALFILTEIVFFGVFFASFFKSSLSPVGLLDGVWVVKQGIWPPPTIKTFEPFDIPFINTL
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
ILLLSGTTVTWAHYALEEKNQKDCVTALALTILLGIFFTTMQAYEYYHAAFKFTDGIYAS
HHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
NFYLATGFHGAHVIIGTIFLIICYFRAKRGDFTTEGNGHLGFEFAAWYWHFVDVVWLFLF
CEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TFVYIFGS
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]