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The map label for this gene is coq7 [H]

Identifier: 229586434

GI number: 229586434

Start: 251416

End: 251955

Strand: Direct

Name: coq7 [H]

Synonym: RAF_ORF0230

Alternate gene names: 229586434

Gene position: 251416-251955 (Clockwise)

Preceding gene: 229586433

Following gene: 229586435

Centisome position: 19.66

GC content: 27.78

Gene sequence:

>540_bases
ATGCCTAGACCTGATTTTTCTGACCCTGACAAACAAATTCACGAGATAATTAGAGTTAATCATGCCGGAGAATATGGTGC
AAAAAGAATTTATCAAGGACAGCTAAAATATATTAAATCTCAAAATGATCGTATATTGATTAAAGAAATGCTTGACCACG
AAGAAGTGCATTTAAATTATTTTGAAAAAAAATTACTGGAAAAAGAAGTGAGACCCACGTTTTTATTATTTTTTTGGCAT
CATTACGGATTTTTACTTGGTGCTTTATCTTCCTTGATGGGAATAAAAACGGCGATGCTTATTACCGAGAGTGTAGAAGA
AGTAATAGAAAAACATTATGAACAGCAAATAAATTATTTAGAAAATAAAAATGTTGAGTCAGAATTATTAAATAATATTA
TTAAATTTCGACTTGATGAAATTGAACATAAAAATATTGCTATAATGAATGATAGTACTGAGGCAATATTTGCAGAAATA
ACTAGTAAAATAGTGAAGATAATTTGTCGTATCTCTATAATTTTAAGTAAGAAAATTTAG

Upstream 100 bases:

>100_bases
GAGGAGCGGAGCGTATACTTCGTGAGTACCCTTAATACGTGAGCACCGTAGCTCTTATAAGATGACGTAGCCAATTTTTC
AAATTAAACGAGTATACATT

Downstream 100 bases:

>100_bases
AGTTAACAACTTAATTAGTTAAAAAATCTAGAAATATTTTACTTCTAAGATATTAAGAAGATAATAAAAAAACATTAGTA
ATATTATTAGAAATGGTGAT

Product: Ubiquinone biosynthesis protein coq7

Products: NA

Alternate protein names: 5-demethoxyubiquinone hydroxylase; DMQ hydroxylase [H]

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MPRPDFSDPDKQIHEIIRVNHAGEYGAKRIYQGQLKYIKSQNDRILIKEMLDHEEVHLNYFEKKLLEKEVRPTFLLFFWH
HYGFLLGALSSLMGIKTAMLITESVEEVIEKHYEQQINYLENKNVESELLNNIIKFRLDEIEHKNIAIMNDSTEAIFAEI
TSKIVKIICRISIILSKKI

Sequences:

>Translated_179_residues
MPRPDFSDPDKQIHEIIRVNHAGEYGAKRIYQGQLKYIKSQNDRILIKEMLDHEEVHLNYFEKKLLEKEVRPTFLLFFWH
HYGFLLGALSSLMGIKTAMLITESVEEVIEKHYEQQINYLENKNVESELLNNIIKFRLDEIEHKNIAIMNDSTEAIFAEI
TSKIVKIICRISIILSKKI
>Mature_178_residues
PRPDFSDPDKQIHEIIRVNHAGEYGAKRIYQGQLKYIKSQNDRILIKEMLDHEEVHLNYFEKKLLEKEVRPTFLLFFWHH
YGFLLGALSSLMGIKTAMLITESVEEVIEKHYEQQINYLENKNVESELLNNIIKFRLDEIEHKNIAIMNDSTEAIFAEIT
SKIVKIICRISIILSKKI

Specific function: Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol [H]

COG id: COG2941

COG function: function code H; Ubiquinone biosynthesis protein COQ7

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COQ7 family [H]

Homologues:

Organism=Homo sapiens, GI25453484, Length=169, Percent_Identity=40.2366863905325, Blast_Score=126, Evalue=1e-29,
Organism=Homo sapiens, GI300244542, Length=169, Percent_Identity=40.2366863905325, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17552756, Length=169, Percent_Identity=33.7278106508876, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324699, Length=179, Percent_Identity=34.6368715083799, Blast_Score=101, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24640215, Length=172, Percent_Identity=40.1162790697674, Blast_Score=130, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012347
- InterPro:   IPR009078
- InterPro:   IPR011566 [H]

Pfam domain/function: PF03232 COQ7 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 21115; Mature: 20984

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPDFSDPDKQIHEIIRVNHAGEYGAKRIYQGQLKYIKSQNDRILIKEMLDHEEVHLNY
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHCHHHHHHHH
FEKKLLEKEVRPTFLLFFWHHYGFLLGALSSLMGIKTAMLITESVEEVIEKHYEQQINYL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENKNVESELLNNIIKFRLDEIEHKNIAIMNDSTEAIFAEITSKIVKIICRISIILSKKI
HCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PRPDFSDPDKQIHEIIRVNHAGEYGAKRIYQGQLKYIKSQNDRILIKEMLDHEEVHLNY
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHCHHHHHHHH
FEKKLLEKEVRPTFLLFFWHHYGFLLGALSSLMGIKTAMLITESVEEVIEKHYEQQINYL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENKNVESELLNNIIKFRLDEIEHKNIAIMNDSTEAIFAEITSKIVKIICRISIILSKKI
HCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]