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The map label for this gene is czcR [H]

Identifier: 229586314

GI number: 229586314

Start: 96276

End: 96989

Strand: Direct

Name: czcR [H]

Synonym: RAF_ORF0097

Alternate gene names: 229586314

Gene position: 96276-96989 (Clockwise)

Preceding gene: 229586313

Following gene: 229586315

Centisome position: 7.53

GC content: 33.89

Gene sequence:

>714_bases
ATGAGAGTTTTGTTAATTGAAGGCGAGCCGGAAATGGCTAACTTAATTGAACTAACTTTAGCTTCAGAAGGGATAGTTTG
CGATAAAGCTTCAGTTGGTGTAGAAGGTTTAAGACTTGGTAAAGTTGGTGGTTATGATCTAGTAATCTTAGACCTTATGT
TACCGGATATTAATGGTTTTGAGATATTACTAAGATTGCGTGCTGCAAAAATAAAAACCCCAATCTTAATTTTATCTAGC
TTAATGGATACGTATCAAAAGATTACTGGTTTCTCTTCCGGAGCCGATGATTATCTAACCAAGCCGTTTGTAAGAGAGGA
ATTAATTGCTAGAATTAAAGCTATAGTTAGACGTTCTAAAGGTCATGCAGCATCAGTATTTAGGTTTGATAAGGTTAGCG
TAAACCTAGATACTAGAAGTGTAGAAGTTGACGGCAAAAAAGTACATTTGACGAACAAAGAATATGCTATTTTAGAGCTA
TTAATACTTCGAAGAGGAACTATCTTAACTAAAGAAATGTTCTTAAATCACTTATATAGTAGTGTTGATGAACCAGAAAT
GAAAATTATTGACGTATTTATTTGTAAACTTCGTAAAAAGTTAAGTGATGCTGCCGGTGGTAGAGATTATATCGACACAG
TATGGGGACGTGGTTATATGCTAAAAGAATATGATGAGTTACAACAAAAAGAAATTTTAGCACAAGGAGCATAA

Upstream 100 bases:

>100_bases
TGTATAAAGCACTAGATAAAAAATTATAATTTAGTTAACAATAATTAACTGTAATTAAATTATAGCACAATATAAAAATT
GAATTTTATGGAGAAAAATA

Downstream 100 bases:

>100_bases
TTAATGCCTTTATCTACTTCTTTACTTGGTAAAAAAAGTACTTATAAAGATAGTTATGATGTAACTTTATTATTTAAAAT
TCCACGTATAAATAATCGAA

Product: Transcriptional activator protein CzcR

Products: NA

Alternate protein names: Response regulator SokA [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MRVLLIEGEPEMANLIELTLASEGIVCDKASVGVEGLRLGKVGGYDLVILDLMLPDINGFEILLRLRAAKIKTPILILSS
LMDTYQKITGFSSGADDYLTKPFVREELIARIKAIVRRSKGHAASVFRFDKVSVNLDTRSVEVDGKKVHLTNKEYAILEL
LILRRGTILTKEMFLNHLYSSVDEPEMKIIDVFICKLRKKLSDAAGGRDYIDTVWGRGYMLKEYDELQQKEILAQGA

Sequences:

>Translated_237_residues
MRVLLIEGEPEMANLIELTLASEGIVCDKASVGVEGLRLGKVGGYDLVILDLMLPDINGFEILLRLRAAKIKTPILILSS
LMDTYQKITGFSSGADDYLTKPFVREELIARIKAIVRRSKGHAASVFRFDKVSVNLDTRSVEVDGKKVHLTNKEYAILEL
LILRRGTILTKEMFLNHLYSSVDEPEMKIIDVFICKLRKKLSDAAGGRDYIDTVWGRGYMLKEYDELQQKEILAQGA
>Mature_237_residues
MRVLLIEGEPEMANLIELTLASEGIVCDKASVGVEGLRLGKVGGYDLVILDLMLPDINGFEILLRLRAAKIKTPILILSS
LMDTYQKITGFSSGADDYLTKPFVREELIARIKAIVRRSKGHAASVFRFDKVSVNLDTRSVEVDGKKVHLTNKEYAILEL
LILRRGTILTKEMFLNHLYSSVDEPEMKIIDVFICKLRKKLSDAAGGRDYIDTVWGRGYMLKEYDELQQKEILAQGA

Specific function: Forms part of a two-component regulatory system CtrA/CckA that controls multiple events in the cell cycle, including cell division, stalk synthesis and cell cycle-specific transcription. Binds to a group of cell cycle-regulated promoters critical for DNA

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=36.7256637168142, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=35.9649122807018, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=35.4260089686099, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.5291479820628, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=30.3030303030303, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=32.7272727272727, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=31.140350877193, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=31.140350877193, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=30.2222222222222, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=27.9279279279279, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=28.3783783783784, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=25.2212389380531, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=26.0504201680672, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26621; Mature: 26621

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLIEGEPEMANLIELTLASEGIVCDKASVGVEGLRLGKVGGYDLVILDLMLPDINGF
CEEEEECCCCCHHHHHHHHCCCCCCEECCCCCCCCCEEECCCCCCCEEEEEECCCCCCHH
EILLRLRAAKIKTPILILSSLMDTYQKITGFSSGADDYLTKPFVREELIARIKAIVRRSK
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCC
GHAASVFRFDKVSVNLDTRSVEVDGKKVHLTNKEYAILELLILRRGTILTKEMFLNHLYS
CCEEEEEEEEEEEEEECCEEEEECCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
SVDEPEMKIIDVFICKLRKKLSDAAGGRDYIDTVWGRGYMLKEYDELQQKEILAQGA
CCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRVLLIEGEPEMANLIELTLASEGIVCDKASVGVEGLRLGKVGGYDLVILDLMLPDINGF
CEEEEECCCCCHHHHHHHHCCCCCCEECCCCCCCCCEEECCCCCCCEEEEEECCCCCCHH
EILLRLRAAKIKTPILILSSLMDTYQKITGFSSGADDYLTKPFVREELIARIKAIVRRSK
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCC
GHAASVFRFDKVSVNLDTRSVEVDGKKVHLTNKEYAILELLILRRGTILTKEMFLNHLYS
CCEEEEEEEEEEEEEECCEEEEECCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
SVDEPEMKIIDVFICKLRKKLSDAAGGRDYIDTVWGRGYMLKEYDELQQKEILAQGA
CCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8548829 [H]