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The map label for this gene is uhpC [H]

Identifier: 229586294

GI number: 229586294

Start: 75316

End: 76611

Strand: Direct

Name: uhpC [H]

Synonym: RAF_ORF0077

Alternate gene names: 229586294

Gene position: 75316-76611 (Clockwise)

Preceding gene: 229586293

Following gene: 229586295

Centisome position: 5.89

GC content: 34.72

Gene sequence:

>1296_bases
ATGACAAATACAAGATCCAAAATTAAAATTCCAAGATCGCCATATGTAAAAAAATATAATAGTTGGCGAGTAAGGATTTT
GTATTCTATTATTATAGGTTACGCAACTTTTTATTTTTGTCGTCAGAATTTTAATATAGCAACTCCTGCTATAAGAGAAT
ATTTTGGGGTTACTAAAACGCAAATTGGCTGGATATTAACTGCTTCATCTATTATGTATGGAGTTAGTAAAGCGTGTAAC
GGGTTTATTAGCGATAAAGTTAATGCTCGGATATTTATGGTTTTGGGTCTTTTATTTGTCGGGATCATTACTATGCTAAT
AGGTTTTTCAGATTCTTTATGGCTTATAGGAATTTTATGGATAGCCAGTAACTGGTTTCAATCTATGGGCTGGCCTCCTG
CAACAAAGATGCTTACTCACTGGTTCGCTTCAAAAGAACTTGGAACTAAATGGGCTATGGGTGCAACTTCTAATCAAATA
GGTGGTGCCCTTGCTATGATAAGCTGCGGTTATTTAATCGATAAATTTGATTGGAGAGCTGCCTTTTTTGTTCCAGGTGT
AGTTGCTTGTGTAGTATCGCTTTTTTTATATAATAGGCTTCGTAATTCTCCAAAAGAAGTAGATTTATCTACCGTAGAGG
AATATAAAGAATATCCGCTTGAAGCTATAGGAGATTATGAGAAGCTATTAACTCCACAATTACTTAAAATGGTCTTTTGT
AATAAGCTAATATGGTATGTTTGTTTAGCAAACATGTTTGTTTATATAATACGTTCCGGAGTAATTTATTGGGCTCCAAC
ATTTTTAAAAGATTTACGTAATATAAGTCTTGCAAATGCAGGCTTACAAATCGGTTTATATGAAATGATAGGTATCCCAG
GGGCATTAATAGCAGGTGTTTTATCTGATAAACTATTTCAAGGTCGTCGAGGTCCTGTTGCATCCATATGTATGGTATTG
CTTAGCTTATTGTTAGTCTTGTTTTGGAAACTTCCTATTCACAGTGAATTATTAAGTATAGTAATTCTTTCTTTAATAGG
CTTTTTTGTTTCAGGACCTCAGCTCCTTGTAGGTATAGCAGCTGCTGATTTTAGTACCCGTCAGGCTGTCGGTACGGCTA
ATGGATTATCAGGATTATTTGGTTATTTAGGAGCGGCTATTGCGGGAGTCGGCGTAGGATGGATTAGCGATAATTATGGT
TGGAATGGGGTATTTATATTTTTCAGTATTTCTGCTCTTTTAGGAGGAGGATTATTTGCTTTAATATGGAATCGTTCAGC
TAAAAAATATATTTAA

Upstream 100 bases:

>100_bases
TATAAAGTTTTGGTAAATAAAACCGAAAATAGAATTTGTTAAAATTTATTTACTGCTAGACTCTTAAACTTGCTTTTTTT
ATACTCGGAGAGTTTATAAT

Downstream 100 bases:

>100_bases
TAATTATAATAAATAGGTTACAAAATGACAATACAATATACTTTTTCAATGATTAAGCCTGATGCTATCAAAAGGAATAA
AATAGGGCAAGTTAATACTT

Product: Sugar phosphate permease

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MTNTRSKIKIPRSPYVKKYNSWRVRILYSIIIGYATFYFCRQNFNIATPAIREYFGVTKTQIGWILTASSIMYGVSKACN
GFISDKVNARIFMVLGLLFVGIITMLIGFSDSLWLIGILWIASNWFQSMGWPPATKMLTHWFASKELGTKWAMGATSNQI
GGALAMISCGYLIDKFDWRAAFFVPGVVACVVSLFLYNRLRNSPKEVDLSTVEEYKEYPLEAIGDYEKLLTPQLLKMVFC
NKLIWYVCLANMFVYIIRSGVIYWAPTFLKDLRNISLANAGLQIGLYEMIGIPGALIAGVLSDKLFQGRRGPVASICMVL
LSLLLVLFWKLPIHSELLSIVILSLIGFFVSGPQLLVGIAAADFSTRQAVGTANGLSGLFGYLGAAIAGVGVGWISDNYG
WNGVFIFFSISALLGGGLFALIWNRSAKKYI

Sequences:

>Translated_431_residues
MTNTRSKIKIPRSPYVKKYNSWRVRILYSIIIGYATFYFCRQNFNIATPAIREYFGVTKTQIGWILTASSIMYGVSKACN
GFISDKVNARIFMVLGLLFVGIITMLIGFSDSLWLIGILWIASNWFQSMGWPPATKMLTHWFASKELGTKWAMGATSNQI
GGALAMISCGYLIDKFDWRAAFFVPGVVACVVSLFLYNRLRNSPKEVDLSTVEEYKEYPLEAIGDYEKLLTPQLLKMVFC
NKLIWYVCLANMFVYIIRSGVIYWAPTFLKDLRNISLANAGLQIGLYEMIGIPGALIAGVLSDKLFQGRRGPVASICMVL
LSLLLVLFWKLPIHSELLSIVILSLIGFFVSGPQLLVGIAAADFSTRQAVGTANGLSGLFGYLGAAIAGVGVGWISDNYG
WNGVFIFFSISALLGGGLFALIWNRSAKKYI
>Mature_430_residues
TNTRSKIKIPRSPYVKKYNSWRVRILYSIIIGYATFYFCRQNFNIATPAIREYFGVTKTQIGWILTASSIMYGVSKACNG
FISDKVNARIFMVLGLLFVGIITMLIGFSDSLWLIGILWIASNWFQSMGWPPATKMLTHWFASKELGTKWAMGATSNQIG
GALAMISCGYLIDKFDWRAAFFVPGVVACVVSLFLYNRLRNSPKEVDLSTVEEYKEYPLEAIGDYEKLLTPQLLKMVFCN
KLIWYVCLANMFVYIIRSGVIYWAPTFLKDLRNISLANAGLQIGLYEMIGIPGALIAGVLSDKLFQGRRGPVASICMVLL
SLLLVLFWKLPIHSELLSIVILSLIGFFVSGPQLLVGIAAADFSTRQAVGTANGLSGLFGYLGAAIAGVGVGWISDNYGW
NGVFIFFSISALLGGGLFALIWNRSAKKYI

Specific function: Transport protein for sugar phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219543, Length=421, Percent_Identity=25.6532066508314, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI256219598, Length=400, Percent_Identity=25.75, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI4503847, Length=400, Percent_Identity=25.75, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI256219483, Length=400, Percent_Identity=25.75, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI256219564, Length=330, Percent_Identity=24.8484848484848, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI223717983, Length=384, Percent_Identity=23.1770833333333, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI38093649, Length=384, Percent_Identity=23.1770833333333, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI46361976, Length=401, Percent_Identity=25.1870324189526, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1788573, Length=426, Percent_Identity=34.037558685446, Blast_Score=274, Evalue=8e-75,
Organism=Escherichia coli, GI87082310, Length=398, Percent_Identity=38.6934673366834, Blast_Score=272, Evalue=4e-74,
Organism=Escherichia coli, GI2367259, Length=406, Percent_Identity=32.0197044334975, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI87082320, Length=411, Percent_Identity=22.8710462287105, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789515, Length=429, Percent_Identity=22.8438228438228, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI2367379, Length=324, Percent_Identity=23.1481481481481, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789152, Length=432, Percent_Identity=20.3703703703704, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI2367193, Length=416, Percent_Identity=21.3942307692308, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17542316, Length=430, Percent_Identity=22.093023255814, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17561094, Length=399, Percent_Identity=24.0601503759398, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI133901856, Length=445, Percent_Identity=20.8988764044944, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI133901854, Length=445, Percent_Identity=20.8988764044944, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17564202, Length=348, Percent_Identity=22.4137931034483, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564204, Length=348, Percent_Identity=22.4137931034483, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI133930953, Length=384, Percent_Identity=23.9583333333333, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24656866, Length=457, Percent_Identity=22.3194748358862, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45550478, Length=457, Percent_Identity=22.3194748358862, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24656861, Length=457, Percent_Identity=22.5382932166302, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47813; Mature: 47682

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTRSKIKIPRSPYVKKYNSWRVRILYSIIIGYATFYFCRQNFNIATPAIREYFGVTKT
CCCCCCCEECCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHH
QIGWILTASSIMYGVSKACNGFISDKVNARIFMVLGLLFVGIITMLIGFSDSLWLIGILW
HHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
IASNWFQSMGWPPATKMLTHWFASKELGTKWAMGATSNQIGGALAMISCGYLIDKFDWRA
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEECCCCCCHHCHHHHHHHHHHHHHCCCCCH
AFFVPGVVACVVSLFLYNRLRNSPKEVDLSTVEEYKEYPLEAIGDYEKLLTPQLLKMVFC
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHH
NKLIWYVCLANMFVYIIRSGVIYWAPTFLKDLRNISLANAGLQIGLYEMIGIPGALIAGV
HHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHCHHHCCCCHHHHHHHHCCCHHHHHHH
LSDKLFQGRRGPVASICMVLLSLLLVLFWKLPIHSELLSIVILSLIGFFVSGPQLLVGIA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHEEEH
AADFSTRQAVGTANGLSGLFGYLGAAIAGVGVGWISDNYGWNGVFIFFSISALLGGGLFA
HHCCHHHHHHCCCCHHHHHHHHHHHHHHHCCHHEECCCCCCCCEEHHHHHHHHHCCCHHE
LIWNRSAKKYI
EHCCCCCCCCC
>Mature Secondary Structure 
TNTRSKIKIPRSPYVKKYNSWRVRILYSIIIGYATFYFCRQNFNIATPAIREYFGVTKT
CCCCCCEECCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHH
QIGWILTASSIMYGVSKACNGFISDKVNARIFMVLGLLFVGIITMLIGFSDSLWLIGILW
HHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
IASNWFQSMGWPPATKMLTHWFASKELGTKWAMGATSNQIGGALAMISCGYLIDKFDWRA
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEECCCCCCHHCHHHHHHHHHHHHHCCCCCH
AFFVPGVVACVVSLFLYNRLRNSPKEVDLSTVEEYKEYPLEAIGDYEKLLTPQLLKMVFC
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHH
NKLIWYVCLANMFVYIIRSGVIYWAPTFLKDLRNISLANAGLQIGLYEMIGIPGALIAGV
HHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHCHHHCCCCHHHHHHHHCCCHHHHHHH
LSDKLFQGRRGPVASICMVLLSLLLVLFWKLPIHSELLSIVILSLIGFFVSGPQLLVGIA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHEEEH
AADFSTRQAVGTANGLSGLFGYLGAAIAGVGVGWISDNYGWNGVFIFFSISALLGGGLFA
HHCCHHHHHHCCCCHHHHHHHHHHHHHHHCCHHEECCCCCCCCEEHHHHHHHHHCCCHHE
LIWNRSAKKYI
EHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]