Definition Rickettsia africae ESF-5 chromosome, complete genome.
Accession NC_012633
Length 1,278,540

Click here to switch to the map view.

The map label for this gene is ftsH [H]

Identifier: 229586278

GI number: 229586278

Start: 59643

End: 61556

Strand: Direct

Name: ftsH [H]

Synonym: RAF_ORF0061

Alternate gene names: 229586278

Gene position: 59643-61556 (Clockwise)

Preceding gene: 229586277

Following gene: 229586279

Centisome position: 4.66

GC content: 37.88

Gene sequence:

>1914_bases
ATGAATAATCAAGGTAGAAGTATTTTAGCTTGGGCAGCACTTTTTATTTTTGTAATATTACTTTTTAATGTGTTCCAATC
TGACAGTTTACTTGGTGGAAGAAATAATATAACTTTCTCGGATTTTTTAACACGAGTTGATGAAAAGACCGTTAATTCGG
TAAAAATTCAGGGTAGAGTAATTGAAGGCACTTCAAATGACGGCTCTACTTTTAATACTTATGCTCCTGATTATCCTGAT
TTAGTAAATCGTCTTACTAGCAATGACGTTAATATTGAAGTAGTGCCTCTTGAAACAAGAATGAATACCTTTTTAGGCTT
TTTAATTTCTTGGTTTCCTATGCTTTTATTGATAGGTGTTTGGGTTTTTTTCATGCGTCAAATGCATGGAGGTGGGAAAG
CCATGGGGTTTGGAAAATCTAAAGCTAGGTTGCTATCAGATAAAGGACCAAAAATTACCTTTAAAGATGTAGCAGGTATC
GATGAAGCAAAAGAAGAATTAACTGAAATAGTGGATTTTTTAAGGGATCCAAGCAAGTTCCAAAAGCTTGGTGGTAAAAT
ACCGAAAGGCTGCTTACTTATAGGTCCTCCCGGAACCGGTAAGACACTTCTTGCTAAAGCAATTGCAGGTGAGGCTAATG
TTCCGTTTTTTAGCATATCCGGCTCTGATTTTGTTGAAATGTTTGTAGGTGTCGGTGCAAGCCGTGTGCGTGACATGTTT
GAACAGGGTAAACGTAATGCTCCTTGTATTATCTTTATCGATGAAATTGATGCGGTAGGTCGTCATAGAGGTATCGGTAT
GGGTGGCGGCAATGATGAACGTGAGCAAACCTTAAACCAAATGTTAGTCGAAATGGATGGATTTGAAGCAAACGAGGGAG
TTGTGATCATTGCAGCTACAAACCGTCCTGACGTTCTTGATCGTGCATTACTGCGTCCCGGTAGGTTTGATCGTCAAATT
GCCGTTGCAAACCCTGATATAAACGGTCGTGAGCAAATTCTAAAAGTACATTTAAAGAAAATTAAATATAATAGTACGGT
ACTAGCACGAATTATTGCTCGCGGTACCCCGGGCTTTTCCGGTGCTGAACTTGCTAACTTAGTTAATGAAGCTGCTCTTA
TTGCTGCAAGGCTTGGTAAGAAAGAAGTAGATATGCACGACATGGAAGAGGCAAAAGATAAGGTGCTGATGGGAGTTGCA
CGTCGCTCCATTGCAATGTCGGAGAAAGAAAAAAGGTTGACTGCATATCATGAAGGCGGACATGCATTAGTAGGACTTTA
TTGTCCTGCAGCATCGCCTATTCATAAGGCTACGATTATACCGCGTGGTAATGCTCTTGGGATGGTGCAAAGACTTCCTG
AAACTGATGAATATTCTCAGAATCGTGAACAGATGGAATCATCTATAGCAGTTTATATGGCAGGAAGAGTAGCGGAGGAA
ATTATTTTCGGTAGAAATAAAGTTACCTCAGGAGCTTCGTCGGATATAAAAGGTGCAACTAATATTGCCAGAGCGATGGT
TACAAAAGCAGGTTTAAGTGATTTAATAGGACCGATATTTCACGGTTCAAGTGGTGACGATATGTATGGTAGACAACCTA
ATAATGAAACCTCGGAAGCTACTGCAGAGTTAATTGATGCTGAAGTTAAAAGAATTATTACGCAAGGATATGAATTTGCA
AAAGATATTTTAACAAAACATATAGATCAACTTCATACCTTAGCAAATGCTTTAATTGAATATGAGACATTGTCCGGTCA
GCAAATTAAAAATTTACTTAGTGGTAGAGCTTTAGATTCAGAAGAGGAGAATAAATTTCCTTTTAATGATTCATCTACTA
TAAAAATAGATAAAGAAAAATCACCTGAGAAAACAAAAACAACTAAAGCTAAAAAAGAAAATTACGCTTCCTAA

Upstream 100 bases:

>100_bases
CACCGGTATTTAAGAGGTTATCTGTAAATAAATTTTAACGATAAAATTTATTTACAGACCTCTCTTATACCAATAAAAAT
TTTTATTAGGTTTTATATCG

Downstream 100 bases:

>100_bases
GTTTAGTAGTATAATTTATGTATAAATTTATAGATTTATTTTGTGGTATCGGTGGTTTTAGAAAAGCCTTGGAAATAAAG
GGTCTTGAATGTGTTTTTTC

Product: ATP-dependent metalloprotease FtsH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MNNQGRSILAWAALFIFVILLFNVFQSDSLLGGRNNITFSDFLTRVDEKTVNSVKIQGRVIEGTSNDGSTFNTYAPDYPD
LVNRLTSNDVNIEVVPLETRMNTFLGFLISWFPMLLLIGVWVFFMRQMHGGGKAMGFGKSKARLLSDKGPKITFKDVAGI
DEAKEELTEIVDFLRDPSKFQKLGGKIPKGCLLIGPPGTGKTLLAKAIAGEANVPFFSISGSDFVEMFVGVGASRVRDMF
EQGKRNAPCIIFIDEIDAVGRHRGIGMGGGNDEREQTLNQMLVEMDGFEANEGVVIIAATNRPDVLDRALLRPGRFDRQI
AVANPDINGREQILKVHLKKIKYNSTVLARIIARGTPGFSGAELANLVNEAALIAARLGKKEVDMHDMEEAKDKVLMGVA
RRSIAMSEKEKRLTAYHEGGHALVGLYCPAASPIHKATIIPRGNALGMVQRLPETDEYSQNREQMESSIAVYMAGRVAEE
IIFGRNKVTSGASSDIKGATNIARAMVTKAGLSDLIGPIFHGSSGDDMYGRQPNNETSEATAELIDAEVKRIITQGYEFA
KDILTKHIDQLHTLANALIEYETLSGQQIKNLLSGRALDSEEENKFPFNDSSTIKIDKEKSPEKTKTTKAKKENYAS

Sequences:

>Translated_637_residues
MNNQGRSILAWAALFIFVILLFNVFQSDSLLGGRNNITFSDFLTRVDEKTVNSVKIQGRVIEGTSNDGSTFNTYAPDYPD
LVNRLTSNDVNIEVVPLETRMNTFLGFLISWFPMLLLIGVWVFFMRQMHGGGKAMGFGKSKARLLSDKGPKITFKDVAGI
DEAKEELTEIVDFLRDPSKFQKLGGKIPKGCLLIGPPGTGKTLLAKAIAGEANVPFFSISGSDFVEMFVGVGASRVRDMF
EQGKRNAPCIIFIDEIDAVGRHRGIGMGGGNDEREQTLNQMLVEMDGFEANEGVVIIAATNRPDVLDRALLRPGRFDRQI
AVANPDINGREQILKVHLKKIKYNSTVLARIIARGTPGFSGAELANLVNEAALIAARLGKKEVDMHDMEEAKDKVLMGVA
RRSIAMSEKEKRLTAYHEGGHALVGLYCPAASPIHKATIIPRGNALGMVQRLPETDEYSQNREQMESSIAVYMAGRVAEE
IIFGRNKVTSGASSDIKGATNIARAMVTKAGLSDLIGPIFHGSSGDDMYGRQPNNETSEATAELIDAEVKRIITQGYEFA
KDILTKHIDQLHTLANALIEYETLSGQQIKNLLSGRALDSEEENKFPFNDSSTIKIDKEKSPEKTKTTKAKKENYAS
>Mature_637_residues
MNNQGRSILAWAALFIFVILLFNVFQSDSLLGGRNNITFSDFLTRVDEKTVNSVKIQGRVIEGTSNDGSTFNTYAPDYPD
LVNRLTSNDVNIEVVPLETRMNTFLGFLISWFPMLLLIGVWVFFMRQMHGGGKAMGFGKSKARLLSDKGPKITFKDVAGI
DEAKEELTEIVDFLRDPSKFQKLGGKIPKGCLLIGPPGTGKTLLAKAIAGEANVPFFSISGSDFVEMFVGVGASRVRDMF
EQGKRNAPCIIFIDEIDAVGRHRGIGMGGGNDEREQTLNQMLVEMDGFEANEGVVIIAATNRPDVLDRALLRPGRFDRQI
AVANPDINGREQILKVHLKKIKYNSTVLARIIARGTPGFSGAELANLVNEAALIAARLGKKEVDMHDMEEAKDKVLMGVA
RRSIAMSEKEKRLTAYHEGGHALVGLYCPAASPIHKATIIPRGNALGMVQRLPETDEYSQNREQMESSIAVYMAGRVAEE
IIFGRNKVTSGASSDIKGATNIARAMVTKAGLSDLIGPIFHGSSGDDMYGRQPNNETSEATAELIDAEVKRIITQGYEFA
KDILTKHIDQLHTLANALIEYETLSGQQIKNLLSGRALDSEEENKFPFNDSSTIKIDKEKSPEKTKTTKAKKENYAS

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [H]

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]

Homologues:

Organism=Homo sapiens, GI21327685, Length=448, Percent_Identity=52.6785714285714, Blast_Score=473, Evalue=1e-133,
Organism=Homo sapiens, GI7657689, Length=448, Percent_Identity=52.6785714285714, Blast_Score=472, Evalue=1e-133,
Organism=Homo sapiens, GI300192933, Length=634, Percent_Identity=42.7444794952681, Blast_Score=457, Evalue=1e-128,
Organism=Homo sapiens, GI4507173, Length=527, Percent_Identity=41.3662239089184, Blast_Score=388, Evalue=1e-108,
Organism=Homo sapiens, GI24497435, Length=266, Percent_Identity=40.2255639097744, Blast_Score=208, Evalue=1e-53,
Organism=Homo sapiens, GI4506209, Length=258, Percent_Identity=39.922480620155, Blast_Score=204, Evalue=3e-52,
Organism=Homo sapiens, GI21361144, Length=245, Percent_Identity=42.4489795918367, Blast_Score=196, Evalue=8e-50,
Organism=Homo sapiens, GI195539395, Length=245, Percent_Identity=40.8163265306122, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI6005942, Length=227, Percent_Identity=42.2907488986784, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI24430151, Length=251, Percent_Identity=37.4501992031873, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI40806173, Length=216, Percent_Identity=46.7592592592593, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI45643123, Length=277, Percent_Identity=38.6281588447653, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI45643125, Length=277, Percent_Identity=38.6281588447653, Blast_Score=180, Evalue=4e-45,
Organism=Homo sapiens, GI89064750, Length=255, Percent_Identity=39.2156862745098, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI5729991, Length=255, Percent_Identity=39.2156862745098, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI157671927, Length=227, Percent_Identity=40.5286343612335, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI24430155, Length=255, Percent_Identity=39.2156862745098, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI194018488, Length=280, Percent_Identity=36.7857142857143, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI229577436, Length=244, Percent_Identity=38.9344262295082, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI4505725, Length=245, Percent_Identity=35.5102040816327, Blast_Score=153, Evalue=5e-37,
Organism=Homo sapiens, GI24497618, Length=235, Percent_Identity=37.0212765957447, Blast_Score=146, Evalue=6e-35,
Organism=Homo sapiens, GI14149767, Length=312, Percent_Identity=32.3717948717949, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI62177112, Length=312, Percent_Identity=32.3717948717949, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI5901990, Length=286, Percent_Identity=33.9160839160839, Blast_Score=144, Evalue=4e-34,
Organism=Homo sapiens, GI153792536, Length=234, Percent_Identity=37.1794871794872, Blast_Score=143, Evalue=6e-34,
Organism=Homo sapiens, GI17865802, Length=235, Percent_Identity=39.5744680851064, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI7019569, Length=240, Percent_Identity=38.75, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI226371754, Length=237, Percent_Identity=35.0210970464135, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI31742536, Length=231, Percent_Identity=35.9307359307359, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI112789543, Length=231, Percent_Identity=35.9307359307359, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI11875211, Length=243, Percent_Identity=39.5061728395062, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI40806170, Length=243, Percent_Identity=39.5061728395062, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI156564401, Length=232, Percent_Identity=37.0689655172414, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI310125282, Length=235, Percent_Identity=36.5957446808511, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI310125280, Length=232, Percent_Identity=36.6379310344828, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI31377644, Length=262, Percent_Identity=32.4427480916031, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI64084766, Length=281, Percent_Identity=29.1814946619217, Blast_Score=106, Evalue=8e-23,
Organism=Homo sapiens, GI116292174, Length=254, Percent_Identity=30.3149606299213, Blast_Score=94, Evalue=6e-19,
Organism=Escherichia coli, GI1789568, Length=599, Percent_Identity=57.2621035058431, Blast_Score=678, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17554264, Length=440, Percent_Identity=50.4545454545455, Blast_Score=434, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI71994521, Length=465, Percent_Identity=47.741935483871, Blast_Score=422, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI115534323, Length=453, Percent_Identity=44.5916114790287, Blast_Score=358, Evalue=4e-99,
Organism=Caenorhabditis elegans, GI25144281, Length=266, Percent_Identity=40.9774436090226, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI25144278, Length=266, Percent_Identity=40.9774436090226, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17554786, Length=266, Percent_Identity=40.6015037593985, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17563248, Length=255, Percent_Identity=41.1764705882353, Blast_Score=205, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI17532375, Length=247, Percent_Identity=40.080971659919, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI71987364, Length=252, Percent_Identity=41.2698412698413, Blast_Score=194, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71987372, Length=252, Percent_Identity=41.2698412698413, Blast_Score=194, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17508701, Length=262, Percent_Identity=39.3129770992366, Blast_Score=192, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17505546, Length=252, Percent_Identity=41.2698412698413, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17563250, Length=251, Percent_Identity=38.2470119521912, Blast_Score=186, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI17531535, Length=245, Percent_Identity=41.6326530612245, Blast_Score=182, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17508053, Length=231, Percent_Identity=41.5584415584416, Blast_Score=181, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17554784, Length=255, Percent_Identity=38.4313725490196, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17537217, Length=237, Percent_Identity=37.5527426160338, Blast_Score=156, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI25153574, Length=234, Percent_Identity=38.034188034188, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI193206114, Length=234, Percent_Identity=38.8888888888889, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI133931034, Length=234, Percent_Identity=38.8888888888889, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI193206116, Length=234, Percent_Identity=38.8888888888889, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI193209502, Length=233, Percent_Identity=37.7682403433476, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17562804, Length=235, Percent_Identity=34.0425531914894, Blast_Score=139, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17570397, Length=178, Percent_Identity=42.6966292134831, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI32566590, Length=178, Percent_Identity=42.6966292134831, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI25146157, Length=248, Percent_Identity=37.5, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI133901662, Length=209, Percent_Identity=40.1913875598086, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI133901658, Length=209, Percent_Identity=39.7129186602871, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI86561515, Length=235, Percent_Identity=35.3191489361702, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17560432, Length=289, Percent_Identity=32.1799307958478, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32563584, Length=226, Percent_Identity=36.7256637168142, Blast_Score=116, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17508421, Length=226, Percent_Identity=36.7256637168142, Blast_Score=116, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17541226, Length=220, Percent_Identity=33.6363636363636, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17541224, Length=220, Percent_Identity=33.6363636363636, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71990294, Length=198, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320854, Length=603, Percent_Identity=43.7810945273632, Blast_Score=456, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6325281, Length=496, Percent_Identity=46.3709677419355, Blast_Score=444, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6323736, Length=497, Percent_Identity=47.887323943662, Blast_Score=440, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6322704, Length=258, Percent_Identity=40.3100775193798, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6324691, Length=262, Percent_Identity=42.3664122137405, Blast_Score=204, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6321390, Length=254, Percent_Identity=39.3700787401575, Blast_Score=200, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6320077, Length=245, Percent_Identity=42.0408163265306, Blast_Score=199, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6324833, Length=246, Percent_Identity=41.0569105691057, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6320197, Length=251, Percent_Identity=37.8486055776892, Blast_Score=187, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6323429, Length=260, Percent_Identity=40.7692307692308, Blast_Score=176, Evalue=7e-45,
Organism=Saccharomyces cerevisiae, GI6320602, Length=248, Percent_Identity=39.1129032258064, Blast_Score=170, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6324000, Length=246, Percent_Identity=38.6178861788618, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6322994, Length=234, Percent_Identity=40.1709401709402, Blast_Score=157, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6322651, Length=261, Percent_Identity=33.7164750957854, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6321709, Length=268, Percent_Identity=34.7014925373134, Blast_Score=151, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6325431, Length=251, Percent_Identity=37.8486055776892, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6319554, Length=306, Percent_Identity=34.640522875817, Blast_Score=133, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6321465, Length=230, Percent_Identity=39.1304347826087, Blast_Score=128, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6325183, Length=247, Percent_Identity=35.6275303643725, Blast_Score=126, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320887, Length=266, Percent_Identity=34.2105263157895, Blast_Score=116, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6320583, Length=193, Percent_Identity=29.5336787564767, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24665814, Length=537, Percent_Identity=46.1824953445065, Blast_Score=449, Evalue=1e-126,
Organism=Drosophila melanogaster, GI28574878, Length=537, Percent_Identity=46.1824953445065, Blast_Score=449, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24658770, Length=494, Percent_Identity=46.9635627530364, Blast_Score=438, Evalue=1e-123,
Organism=Drosophila melanogaster, GI24639391, Length=627, Percent_Identity=38.755980861244, Blast_Score=417, Evalue=1e-116,
Organism=Drosophila melanogaster, GI45554047, Length=340, Percent_Identity=38.8235294117647, Blast_Score=223, Evalue=5e-58,
Organism=Drosophila melanogaster, GI24651451, Length=264, Percent_Identity=41.2878787878788, Blast_Score=210, Evalue=3e-54,
Organism=Drosophila melanogaster, GI19920408, Length=266, Percent_Identity=39.8496240601504, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI17137738, Length=255, Percent_Identity=40.3921568627451, Blast_Score=201, Evalue=9e-52,
Organism=Drosophila melanogaster, GI161076486, Length=229, Percent_Identity=42.7947598253275, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI17137560, Length=229, Percent_Identity=42.7947598253275, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI161076488, Length=229, Percent_Identity=42.7947598253275, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24640100, Length=245, Percent_Identity=40.8163265306122, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI17738151, Length=246, Percent_Identity=40.650406504065, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI19921202, Length=249, Percent_Identity=39.7590361445783, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24649446, Length=251, Percent_Identity=37.8486055776892, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24663015, Length=245, Percent_Identity=39.1836734693878, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI281365776, Length=234, Percent_Identity=42.7350427350427, Blast_Score=183, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24660075, Length=234, Percent_Identity=42.7350427350427, Blast_Score=183, Evalue=4e-46,
Organism=Drosophila melanogaster, GI45552965, Length=234, Percent_Identity=42.7350427350427, Blast_Score=182, Evalue=5e-46,
Organism=Drosophila melanogaster, GI281361487, Length=249, Percent_Identity=38.9558232931727, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI18860063, Length=253, Percent_Identity=38.3399209486166, Blast_Score=172, Evalue=7e-43,
Organism=Drosophila melanogaster, GI24652279, Length=189, Percent_Identity=44.4444444444444, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24656825, Length=248, Percent_Identity=37.9032258064516, Blast_Score=170, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24656820, Length=248, Percent_Identity=37.9032258064516, Blast_Score=170, Evalue=3e-42,
Organism=Drosophila melanogaster, GI281363136, Length=247, Percent_Identity=36.8421052631579, Blast_Score=156, Evalue=5e-38,
Organism=Drosophila melanogaster, GI78707192, Length=247, Percent_Identity=36.8421052631579, Blast_Score=156, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24644145, Length=288, Percent_Identity=34.0277777777778, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI18859657, Length=234, Percent_Identity=39.7435897435897, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI281360136, Length=286, Percent_Identity=32.5174825174825, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24644411, Length=286, Percent_Identity=32.5174825174825, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI281360144, Length=286, Percent_Identity=32.5174825174825, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI281360140, Length=286, Percent_Identity=32.5174825174825, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI281360146, Length=286, Percent_Identity=32.5174825174825, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281360138, Length=286, Percent_Identity=32.5174825174825, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281360142, Length=286, Percent_Identity=32.5174825174825, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI21357333, Length=286, Percent_Identity=32.5174825174825, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24581396, Length=233, Percent_Identity=37.7682403433476, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21355121, Length=205, Percent_Identity=33.6585365853659, Blast_Score=134, Evalue=3e-31,
Organism=Drosophila melanogaster, GI28573010, Length=234, Percent_Identity=38.8888888888889, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI28571849, Length=232, Percent_Identity=38.7931034482759, Blast_Score=132, Evalue=9e-31,
Organism=Drosophila melanogaster, GI28571847, Length=232, Percent_Identity=38.7931034482759, Blast_Score=132, Evalue=9e-31,
Organism=Drosophila melanogaster, GI17864540, Length=236, Percent_Identity=38.9830508474576, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI20129529, Length=307, Percent_Identity=31.2703583061889, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI20129423, Length=233, Percent_Identity=34.7639484978541, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24639486, Length=267, Percent_Identity=31.8352059925094, Blast_Score=103, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642 [H]

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 69886; Mature: 69886

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MNNQGRSILAWAALFIFVILLFNVFQSDSLLGGRNNITFSDFLTRVDEKTVNSVKIQGRV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCEEEEEEEE
IEGTSNDGSTFNTYAPDYPDLVNRLTSNDVNIEVVPLETRMNTFLGFLISWFPMLLLIGV
EECCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
WVFFMRQMHGGGKAMGFGKSKARLLSDKGPKITFKDVAGIDEAKEELTEIVDFLRDPSKF
HHHHHHHHCCCCCCCCCCCHHHHHHCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHCHHHH
QKLGGKIPKGCLLIGPPGTGKTLLAKAIAGEANVPFFSISGSDFVEMFVGVGASRVRDMF
HHHCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHCCHHHHHHHH
EQGKRNAPCIIFIDEIDAVGRHRGIGMGGGNDEREQTLNQMLVEMDGFEANEGVVIIAAT
HHCCCCCCEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
NRPDVLDRALLRPGRFDRQIAVANPDINGREQILKVHLKKIKYNSTVLARIIARGTPGFS
CCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
GAELANLVNEAALIAARLGKKEVDMHDMEEAKDKVLMGVARRSIAMSEKEKRLTAYHEGG
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
HALVGLYCPAASPIHKATIIPRGNALGMVQRLPETDEYSQNREQMESSIAVYMAGRVAEE
CEEEEEECCCCCCCCCEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IIFGRNKVTSGASSDIKGATNIARAMVTKAGLSDLIGPIFHGSSGDDMYGRQPNNETSEA
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
TAELIDAEVKRIITQGYEFAKDILTKHIDQLHTLANALIEYETLSGQQIKNLLSGRALDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCC
EEENKFPFNDSSTIKIDKEKSPEKTKTTKAKKENYAS
CCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNNQGRSILAWAALFIFVILLFNVFQSDSLLGGRNNITFSDFLTRVDEKTVNSVKIQGRV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCEEEEEEEE
IEGTSNDGSTFNTYAPDYPDLVNRLTSNDVNIEVVPLETRMNTFLGFLISWFPMLLLIGV
EECCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
WVFFMRQMHGGGKAMGFGKSKARLLSDKGPKITFKDVAGIDEAKEELTEIVDFLRDPSKF
HHHHHHHHCCCCCCCCCCCHHHHHHCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHCHHHH
QKLGGKIPKGCLLIGPPGTGKTLLAKAIAGEANVPFFSISGSDFVEMFVGVGASRVRDMF
HHHCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHCCHHHHHHHH
EQGKRNAPCIIFIDEIDAVGRHRGIGMGGGNDEREQTLNQMLVEMDGFEANEGVVIIAAT
HHCCCCCCEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
NRPDVLDRALLRPGRFDRQIAVANPDINGREQILKVHLKKIKYNSTVLARIIARGTPGFS
CCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
GAELANLVNEAALIAARLGKKEVDMHDMEEAKDKVLMGVARRSIAMSEKEKRLTAYHEGG
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
HALVGLYCPAASPIHKATIIPRGNALGMVQRLPETDEYSQNREQMESSIAVYMAGRVAEE
CEEEEEECCCCCCCCCEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IIFGRNKVTSGASSDIKGATNIARAMVTKAGLSDLIGPIFHGSSGDDMYGRQPNNETSEA
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
TAELIDAEVKRIITQGYEFAKDILTKHIDQLHTLANALIEYETLSGQQIKNLLSGRALDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCC
EEENKFPFNDSSTIKIDKEKSPEKTKTTKAKKENYAS
CCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]