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The map label for this gene is argD [H]

Identifier: 229576698

GI number: 229576698

Start: 3958982

End: 3960142

Strand: Reverse

Name: argD [H]

Synonym: BALH_3744

Alternate gene names: 229576698

Gene position: 3960142-3958982 (Counterclockwise)

Preceding gene: 229576697

Following gene: 118479327

Centisome position: 75.33

GC content: 38.24

Gene sequence:

>1161_bases
ATGACAAGTCATCTTTTTCAAACGTATGGGAGAAGAAATATTGAGCTTGTAAAGGGAAGTGGAACGAAAGTCGTTGATGA
AAATGGTAAGCAATATTTAGATTTCACATCAGGAATTGGTGTATGTAATTTAGGGCATTGCCATCCTACTGTTATGAAAG
CGGTACAAGAGCAACTTAATGATATATGGCATATATCTAATCTGTTTACAAACAGCTTACAAGAAGAAGTCGCGTCATTA
TTAACAGAAAATATAGCATTAGATTATGTGTTCTTCTGTAATAGCGGGGCAGAGGCGAATGAAGCAGCTTTGAAGCTAGC
CCGTAAGCATACTGGAAAATCTCTCGTCGTAACGTGTGAACAGTCTTTTCACGGTAGAACATTCGGAACGATGAGTGCGA
CGGGACAAAATAAAGTGAAAGAAGGATTTGGTCCGCTCCTTCCGTCTTTTTTACATACCCCCTTTAACGATATAAAAGCG
TTAGAGGAAGTAATGAATGAAGAAGTTGCGGCAGTAATGGTAGAAGTTGTGCAAGGAGAGGGAGGAGTCATACCTGCTGA
TCTATCCTTTTTGCGAGAGATTGAAGCATTATGTAATAAGTCCGGTTCCCTATTTATTATAGATGAAGTACAAACAGGGA
TCGGAAGAACAGGTACATTATTTGCTTACGAACAAATGGGAATACATCCTCATATCGTTACTACCGCTAAGGCGCTTGGA
AACGGAATTCCAGTTGGAGCAATGATTGGCCGGAAAGAACTTGGAACATCGTTTCCTGCAGGATCACACGGTTCAACGTT
TGGTGGAAATTATATTGCAATGGCTGCAGCGAAAGAAGTATTGCAAATAACTAAGAAACCATCGTTTTTAAAAGAAGTAA
AGGAAAAGGGCGAGTACATATTACAGAAGTTGCAAGAGGAATTACGACATGTCGAATGTATTCAAAATATACGTGGTAAG
GGGCTTATGATTGGAATTGAGTGTACGCATGAGGTTTCAAGTTTTATAGAACAACTAGAGAAAGAAGGGCTTCTTGTATT
ACAAGCAGGACCTAATGTTATAAGACTATTACCACCACTCATTATAACGAATGAAGAGTTAGAACAGGCAGTATATATGA
TAAAAAAAGTAGTTTGTACAAAAAACGTATCAATTATATAA

Upstream 100 bases:

>100_bases
TGGGAGTGCAAAAGATAAGTATTGTGAACGGTACAAAAGATTTTACTGAAGTTACGGGAGAGTGTATTGGAACGACGGTA
ACGAAAGGAGTAAGTATCGT

Downstream 100 bases:

>100_bases
GGGGGAACTTCCATGTCAACTGTACAAGTACCAAAATTAAATACGAAAGATCTTTTAACATTAGAAGAATTGACGCAAGA
AGAAATCATTTCATTAATTG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MTSHLFQTYGRRNIELVKGSGTKVVDENGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLNDIWHISNLFTNSLQEEVASL
LTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCEQSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKA
LEEVMNEEVAAVMVEVVQGEGGVIPADLSFLREIEALCNKSGSLFIIDEVQTGIGRTGTLFAYEQMGIHPHIVTTAKALG
NGIPVGAMIGRKELGTSFPAGSHGSTFGGNYIAMAAAKEVLQITKKPSFLKEVKEKGEYILQKLQEELRHVECIQNIRGK
GLMIGIECTHEVSSFIEQLEKEGLLVLQAGPNVIRLLPPLIITNEELEQAVYMIKKVVCTKNVSII

Sequences:

>Translated_386_residues
MTSHLFQTYGRRNIELVKGSGTKVVDENGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLNDIWHISNLFTNSLQEEVASL
LTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCEQSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKA
LEEVMNEEVAAVMVEVVQGEGGVIPADLSFLREIEALCNKSGSLFIIDEVQTGIGRTGTLFAYEQMGIHPHIVTTAKALG
NGIPVGAMIGRKELGTSFPAGSHGSTFGGNYIAMAAAKEVLQITKKPSFLKEVKEKGEYILQKLQEELRHVECIQNIRGK
GLMIGIECTHEVSSFIEQLEKEGLLVLQAGPNVIRLLPPLIITNEELEQAVYMIKKVVCTKNVSII
>Mature_385_residues
TSHLFQTYGRRNIELVKGSGTKVVDENGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLNDIWHISNLFTNSLQEEVASLL
TENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCEQSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKAL
EEVMNEEVAAVMVEVVQGEGGVIPADLSFLREIEALCNKSGSLFIIDEVQTGIGRTGTLFAYEQMGIHPHIVTTAKALGN
GIPVGAMIGRKELGTSFPAGSHGSTFGGNYIAMAAAKEVLQITKKPSFLKEVKEKGEYILQKLQEELRHVECIQNIRGKG
LMIGIECTHEVSSFIEQLEKEGLLVLQAGPNVIRLLPPLIITNEELEQAVYMIKKVVCTKNVSII

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=391, Percent_Identity=32.7365728900256, Blast_Score=212, Evalue=5e-55,
Organism=Homo sapiens, GI13994255, Length=433, Percent_Identity=30.2540415704388, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=33.8870431893688, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI37574042, Length=408, Percent_Identity=29.1666666666667, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI24119277, Length=408, Percent_Identity=27.2058823529412, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI226442709, Length=378, Percent_Identity=28.5714285714286, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI226442705, Length=408, Percent_Identity=28.1862745098039, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI188536080, Length=410, Percent_Identity=23.9024390243902, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI38679950, Length=410, Percent_Identity=23.9024390243902, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI38679946, Length=410, Percent_Identity=23.9024390243902, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1789759, Length=376, Percent_Identity=40.4255319148936, Blast_Score=302, Evalue=3e-83,
Organism=Escherichia coli, GI1788044, Length=361, Percent_Identity=42.1052631578947, Blast_Score=301, Evalue=6e-83,
Organism=Escherichia coli, GI145693181, Length=395, Percent_Identity=35.9493670886076, Blast_Score=237, Evalue=9e-64,
Organism=Escherichia coli, GI1789016, Length=396, Percent_Identity=33.5858585858586, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1787560, Length=386, Percent_Identity=34.4559585492228, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1786991, Length=404, Percent_Identity=28.4653465346535, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1786349, Length=335, Percent_Identity=30.1492537313433, Blast_Score=128, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI25144271, Length=384, Percent_Identity=35.15625, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=434, Percent_Identity=31.7972350230415, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI25144274, Length=376, Percent_Identity=30.8510638297872, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI71992977, Length=425, Percent_Identity=28.7058823529412, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71981843, Length=186, Percent_Identity=31.7204301075269, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17541228, Length=438, Percent_Identity=22.3744292237443, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71992985, Length=116, Percent_Identity=32.7586206896552, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324432, Length=392, Percent_Identity=36.2244897959184, Blast_Score=255, Evalue=6e-69,
Organism=Saccharomyces cerevisiae, GI6323470, Length=391, Percent_Identity=33.5038363171356, Blast_Score=208, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6324386, Length=348, Percent_Identity=26.4367816091954, Blast_Score=100, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6321456, Length=366, Percent_Identity=25.9562841530055, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21357415, Length=389, Percent_Identity=31.3624678663239, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI28574759, Length=403, Percent_Identity=31.5136476426799, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI161085790, Length=403, Percent_Identity=31.2655086848635, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21356575, Length=408, Percent_Identity=30.3921568627451, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI281366494, Length=424, Percent_Identity=25, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24667139, Length=424, Percent_Identity=25, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24667143, Length=424, Percent_Identity=25, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42161; Mature: 42030

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSHLFQTYGRRNIELVKGSGTKVVDENGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLN
CCCHHHHHHCCCCEEEEECCCCEEECCCCCEEEECCCCCCEECCCCCCHHHHHHHHHHHH
DIWHISNLFTNSLQEEVASLLTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEC
QSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKALEEVMNEEVAAVMVEVVQGE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
GGVIPADLSFLREIEALCNKSGSLFIIDEVQTGIGRTGTLFAYEQMGIHPHIVTTAKALG
CCCCHHHHHHHHHHHHHHCCCCCEEEEECHHHCCCCCCEEEEHHHCCCCCHHHHHHHHHC
NGIPVGAMIGRKELGTSFPAGSHGSTFGGNYIAMAAAKEVLQITKKPSFLKEVKEKGEYI
CCCCCHHHHCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LQKLQEELRHVECIQNIRGKGLMIGIECTHEVSSFIEQLEKEGLLVLQAGPNVIRLLPPL
HHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCEEEEECCCCHHHHCCCC
IITNEELEQAVYMIKKVVCTKNVSII
EECCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TSHLFQTYGRRNIELVKGSGTKVVDENGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLN
CCHHHHHHCCCCEEEEECCCCEEECCCCCEEEECCCCCCEECCCCCCHHHHHHHHHHHH
DIWHISNLFTNSLQEEVASLLTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEC
QSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKALEEVMNEEVAAVMVEVVQGE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
GGVIPADLSFLREIEALCNKSGSLFIIDEVQTGIGRTGTLFAYEQMGIHPHIVTTAKALG
CCCCHHHHHHHHHHHHHHCCCCCEEEEECHHHCCCCCCEEEEHHHCCCCCHHHHHHHHHC
NGIPVGAMIGRKELGTSFPAGSHGSTFGGNYIAMAAAKEVLQITKKPSFLKEVKEKGEYI
CCCCCHHHHCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LQKLQEELRHVECIQNIRGKGLMIGIECTHEVSSFIEQLEKEGLLVLQAGPNVIRLLPPL
HHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCEEEEECCCCHHHHCCCC
IITNEELEQAVYMIKKVVCTKNVSII
EECCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]