Click here to switch to the map view.

The map label for this gene is arcB [H]

Identifier: 118479327

GI number: 118479327

Start: 3958019

End: 3958969

Strand: Reverse

Name: arcB [H]

Synonym: BALH_3743

Alternate gene names: 118479327

Gene position: 3958969-3958019 (Counterclockwise)

Preceding gene: 229576698

Following gene: 118479326

Centisome position: 75.31

GC content: 36.17

Gene sequence:

>951_bases
ATGTCAACTGTACAAGTACCAAAATTAAATACGAAAGATCTTTTAACATTAGAAGAATTGACGCAAGAAGAAATCATTTC
ATTAATTGAGTTCGCTATCTATTTAAAAAAGAATAAGCAGGAGCCTTTATTACAAGGAAAAATATTAGGGCTTATCTTTG
ATAAACATTCAACTCGTACTCGCGTATCTTTTGAAGCAGGAATGGTACAGCTCGGGGGACATGGCATGTTTTTAAGTGGG
AAAGAGATGCAAATTGGAAGAGGGGAAACTGTTTCAGATACTGCGAAAGTATTATCTCATTATATTGACGGAATCATGAT
ACGTACATTCTCACATGCGGATGTAGAAGAGCTTGCAAAAGAATCGAGCATACCTGTAATTAACGGTTTAACGGACGATC
ATCATCCTTGTCAAGCATTGGCAGACTTAATGACAATATATGAAGAAAAAAATACATTTAAAGGAATAAAAGTGGCTTAC
GTAGGTGACGGAAATAATGTATGTCATTCATTGTTGTTAGCGAGTGCGAAAGTCGGAATGCATATGACTGTTGCAACACC
TGTAGGGTATGAACCAAATGAGGAAATTATAAAAAAAGCGTTAACGATTGCTGAAGAAACAGGAGCGAAAATTGAAATTT
TGCATAACCCTGAACTAGCGGTGAATGAAGCAGATTTCATTTATACTGACGTTTGGATGAGCATGGGGCAAGAGGGCGAA
GAAGAGAAATATACTTTATTTCAACCATACCAAATCAATAAAGAACTTGTTATGCATGCAAAGCAAACGTATCGTTTCTT
ACACTGTTTACCTGCCCATCGTGAAGAGGAAGTAACAGGAGAAATTATAGATGGACCACAGTCTATCGTCTTTGAGCAAG
CTGGTAATCGATTACATGCGCAAAAAGCATTATTAGTAAGTTTATTTAAAAATGTAGAAGAGCTTTCTTAA

Upstream 100 bases:

>100_bases
ACCACTCATTATAACGAATGAAGAGTTAGAACAGGCAGTATATATGATAAAAAAAGTAGTTTGTACAAAAAACGTATCAA
TTATATAAGGGGGAACTTCC

Downstream 100 bases:

>100_bases
ATGATGTGCATCTCCAATTGTTACGTACAAATAACAATTGGAGGTGCACTTTTTGTATTGAAGAGTCATATGTATATTTA
GTTAACCATTTTGATATCAT

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSTVQVPKLNTKDLLTLEELTQEEIISLIEFAIYLKKNKQEPLLQGKILGLIFDKHSTRTRVSFEAGMVQLGGHGMFLSG
KEMQIGRGETVSDTAKVLSHYIDGIMIRTFSHADVEELAKESSIPVINGLTDDHHPCQALADLMTIYEEKNTFKGIKVAY
VGDGNNVCHSLLLASAKVGMHMTVATPVGYEPNEEIIKKALTIAEETGAKIEILHNPELAVNEADFIYTDVWMSMGQEGE
EEKYTLFQPYQINKELVMHAKQTYRFLHCLPAHREEEVTGEIIDGPQSIVFEQAGNRLHAQKALLVSLFKNVEELS

Sequences:

>Translated_316_residues
MSTVQVPKLNTKDLLTLEELTQEEIISLIEFAIYLKKNKQEPLLQGKILGLIFDKHSTRTRVSFEAGMVQLGGHGMFLSG
KEMQIGRGETVSDTAKVLSHYIDGIMIRTFSHADVEELAKESSIPVINGLTDDHHPCQALADLMTIYEEKNTFKGIKVAY
VGDGNNVCHSLLLASAKVGMHMTVATPVGYEPNEEIIKKALTIAEETGAKIEILHNPELAVNEADFIYTDVWMSMGQEGE
EEKYTLFQPYQINKELVMHAKQTYRFLHCLPAHREEEVTGEIIDGPQSIVFEQAGNRLHAQKALLVSLFKNVEELS
>Mature_315_residues
STVQVPKLNTKDLLTLEELTQEEIISLIEFAIYLKKNKQEPLLQGKILGLIFDKHSTRTRVSFEAGMVQLGGHGMFLSGK
EMQIGRGETVSDTAKVLSHYIDGIMIRTFSHADVEELAKESSIPVINGLTDDHHPCQALADLMTIYEEKNTFKGIKVAYV
GDGNNVCHSLLLASAKVGMHMTVATPVGYEPNEEIIKKALTIAEETGAKIEILHNPELAVNEADFIYTDVWMSMGQEGEE
EKYTLFQPYQINKELVMHAKQTYRFLHCLPAHREEEVTGEIIDGPQSIVFEQAGNRLHAQKALLVSLFKNVEELS

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=310, Percent_Identity=43.8709677419355, Blast_Score=268, Evalue=4e-72,
Organism=Homo sapiens, GI18105007, Length=310, Percent_Identity=28.3870967741935, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1790703, Length=324, Percent_Identity=37.037037037037, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI1786469, Length=327, Percent_Identity=37.0030581039755, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI2367364, Length=309, Percent_Identity=31.3915857605178, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI48994908, Length=358, Percent_Identity=25.6983240223464, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193204318, Length=323, Percent_Identity=27.5541795665635, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322373, Length=320, Percent_Identity=38.125, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6322331, Length=272, Percent_Identity=32.7205882352941, Blast_Score=98, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24642586, Length=309, Percent_Identity=28.4789644012945, Blast_Score=105, Evalue=5e-23,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 35341; Mature: 35210

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVQVPKLNTKDLLTLEELTQEEIISLIEFAIYLKKNKQEPLLQGKILGLIFDKHSTRT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCEEEEEEEECCCCCE
RVSFEAGMVQLGGHGMFLSGKEMQIGRGETVSDTAKVLSHYIDGIMIRTFSHADVEELAK
EEEEECCEEEECCCEEEECCCCEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHH
ESSIPVINGLTDDHHPCQALADLMTIYEEKNTFKGIKVAYVGDGNNVCHSLLLASAKVGM
HCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHCCE
HMTVATPVGYEPNEEIIKKALTIAEETGAKIEILHNPELAVNEADFIYTDVWMSMGQEGE
EEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCEEECCCCHHHHHHHHHCCCCCC
EEKYTLFQPYQINKELVMHAKQTYRFLHCLPAHREEEVTGEIIDGPQSIVFEQAGNRLHA
CCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHHCCHHHH
QKALLVSLFKNVEELS
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STVQVPKLNTKDLLTLEELTQEEIISLIEFAIYLKKNKQEPLLQGKILGLIFDKHSTRT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCEEEEEEEECCCCCE
RVSFEAGMVQLGGHGMFLSGKEMQIGRGETVSDTAKVLSHYIDGIMIRTFSHADVEELAK
EEEEECCEEEECCCEEEECCCCEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHH
ESSIPVINGLTDDHHPCQALADLMTIYEEKNTFKGIKVAYVGDGNNVCHSLLLASAKVGM
HCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHCCE
HMTVATPVGYEPNEEIIKKALTIAEETGAKIEILHNPELAVNEADFIYTDVWMSMGQEGE
EEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCEEECCCCHHHHHHHHHCCCCCC
EEKYTLFQPYQINKELVMHAKQTYRFLHCLPAHREEEVTGEIIDGPQSIVFEQAGNRLHA
CCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHHCCHHHH
QKALLVSLFKNVEELS
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA