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The map label for this gene is hslV [H]

Identifier: 229170803

GI number: 229170803

Start: 422031

End: 422561

Strand: Reverse

Name: hslV [H]

Synonym: Psyr_0395

Alternate gene names: 229170803

Gene position: 422561-422031 (Counterclockwise)

Preceding gene: 66043663

Following gene: 66043661

Centisome position: 6.93

GC content: 62.34

Gene sequence:

>531_bases
TTGACCACCATCGTTTCAGTGCGCCGCCACGGTAAAGTCGTCATGGCTGGCGACGGCCAGGTTTCTCTGGGCAACACCGT
CATGAAAGGCAACGCCAAGAAGGTACGCCGCCTGTATCACGGTGAAGTGATCGCCGGATTCGCTGGCGCGACCGCCGATG
CATTCACGCTGTTCGAACGCTTCGAGGCCCAACTGGAAAAACACCAGGGGCATCTGGTTCGTGCAGCCGTCGAACTGGCC
AAGGACTGGCGCACCGATCGCTCGCTGAGCCGCCTTGAAGCCATGCTGGCCGTCGCCAACAAGGACGCCTCGCTGATCAT
CACCGGCAACGGTGACGTGGTCGAGCCCGAGGACGGACTGATCGCCATGGGCTCCGGCGGCGCATTCGCTCAGGCCGCAG
CACGCGCCCTGCTGCTCAAGACCGACCTGTCGGCCCGCGAAATTGCCGAGACTTCCCTGCATATCGCCGGCGACATTTGC
GTGTTCACCAACCACAACATCACCATTGAGGAGCAGGACCTCGCCGGCTAA

Upstream 100 bases:

>100_bases
TCATTCCCCCCCGATTCATCCCCAAGGTTGAAATACTCACCCACACCCCCATATGAGTTTGCATCAGGGCATTTTCGCCC
CGCAGTGTGGAGACTCTCCC

Downstream 100 bases:

>100_bases
GCCGCTGCCGGGCCGCACATCTTGCGGCCCCATCGACTTGACCGTACCAGAGGACCGTGAATAACCATGTCAATGACTCC
CCGCGAAATCGTCCATGAAC

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MTTIVSVRRHGKVVMAGDGQVSLGNTVMKGNAKKVRRLYHGEVIAGFAGATADAFTLFERFEAQLEKHQGHLVRAAVELA
KDWRTDRSLSRLEAMLAVANKDASLIITGNGDVVEPEDGLIAMGSGGAFAQAAARALLLKTDLSAREIAETSLHIAGDIC
VFTNHNITIEEQDLAG

Sequences:

>Translated_176_residues
MTTIVSVRRHGKVVMAGDGQVSLGNTVMKGNAKKVRRLYHGEVIAGFAGATADAFTLFERFEAQLEKHQGHLVRAAVELA
KDWRTDRSLSRLEAMLAVANKDASLIITGNGDVVEPEDGLIAMGSGGAFAQAAARALLLKTDLSAREIAETSLHIAGDIC
VFTNHNITIEEQDLAG
>Mature_175_residues
TTIVSVRRHGKVVMAGDGQVSLGNTVMKGNAKKVRRLYHGEVIAGFAGATADAFTLFERFEAQLEKHQGHLVRAAVELAK
DWRTDRSLSRLEAMLAVANKDASLIITGNGDVVEPEDGLIAMGSGGAFAQAAARALLLKTDLSAREIAETSLHIAGDICV
FTNHNITIEEQDLAG

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery [H]

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790367, Length=171, Percent_Identity=77.7777777777778, Blast_Score=268, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022281
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: 3.4.25.-

Molecular weight: Translated: 18769; Mature: 18637

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIVSVRRHGKVVMAGDGQVSLGNTVMKGNAKKVRRLYHGEVIAGFAGATADAFTLFER
CCCEEEEHHCCEEEEECCCCEEECCEEEECCHHHHHHHHCCCEEEECCCCCHHHHHHHHH
FEAQLEKHQGHLVRAAVELAKDWRTDRSLSRLEAMLAVANKDASLIITGNGDVVEPEDGL
HHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCE
IAMGSGGAFAQAAARALLLKTDLSAREIAETSLHIAGDICVFTNHNITIEEQDLAG
EEEECCCHHHHHHHHHHHEECCCCHHHHHHHHEEEECEEEEEECCCEEEECCCCCC
>Mature Secondary Structure 
TTIVSVRRHGKVVMAGDGQVSLGNTVMKGNAKKVRRLYHGEVIAGFAGATADAFTLFER
CCEEEEHHCCEEEEECCCCEEECCEEEECCHHHHHHHHCCCEEEECCCCCHHHHHHHHH
FEAQLEKHQGHLVRAAVELAKDWRTDRSLSRLEAMLAVANKDASLIITGNGDVVEPEDGL
HHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCE
IAMGSGGAFAQAAARALLLKTDLSAREIAETSLHIAGDICVFTNHNITIEEQDLAG
EEEECCCHHHHHHHHHHHEECCCCHHHHHHHHEEEECEEEEEECCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA