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The map label for this gene is gbh [H]

Identifier: 227828818

GI number: 227828818

Start: 2410508

End: 2411425

Strand: Direct

Name: gbh [H]

Synonym: M1425_2592

Alternate gene names: 227828818

Gene position: 2410508-2411425 (Clockwise)

Preceding gene: 227828817

Following gene: 227828821

Centisome position: 92.4

GC content: 38.13

Gene sequence:

>918_bases
ATGAGGCAAATAGACGCGTTAAAATCTCCACGCTTCACACAAATTTCTACCTTCGGTAGATTACCAATTTGCGGAAGAGA
TGAGGAAATAAAGGCGGCGTTTTTAGGAATACCTTTCGATGATGCTGTAACTTATAGACCGGGAGCCAGATTTGGACCAA
TGGGAATAAGACAAGGATCTAGATTATTAAGACCTTACAATCAATTCCTAGATACTTATCCTTTTGATAAGCTTAACGCT
TGTGATATGGGTGATATAAACATTATTCCGGGGTACATTGAGGATACAATGAACATAATACAAACGAATCTTTACGAAAT
AATATCATCAAAAAACCTAGTGCCCTTTATAGCTGGTGGAGATCACTCAATCACGTTACCCGTTTTAAGGGCTTTAAATA
AGAAGTATGGAAAAATAAATATCATACACTTGGATTCACATTACGACTTCTGGGATTCCTATTGGGGTAAGAAACATACG
CATGGTACGTGGTTGAGGAGGGCAATTGAAGAGGGCTTAATCAAAGAAGCTATACAAGGAGGAATTAGGGCCTCAACGTT
CTCGAAAGAAGATCTTAAAGATAAGGAGAGGTTAGGAGTGAAGAGTTTCACAATTAGAGATTTAAAGTATAATTTAGATT
CTGTTATAAGGGAAATAAATTCCCTATCTGGTCCCACACACGTTTCCATTGATATAGATGTTGTAGATCCGGCGTTTGCC
CCTGGGACTGGTACGCCAGAAGTGGGTGGTTTGACAAGCTTCGAAATTATAGAAATTATCAGAAAGCTGAGATTTGATAA
ACTAGTTGGATTTGATGTTGTAGAAGTTGCCCCACCATATGATGTAAGCGAAATCACCACAATGTTAGCTGCGAATATTA
TCTATGAAGGAATGAGCGTACTCTCACTAAATCTTTAA

Upstream 100 bases:

>100_bases
ACACAATAACATTAGTTATGGCAAAGAAGTAAAGACTCGTTTATAAGAAGGACTATCTTATAACGTTAAATTAAAAATAT
CATAAAAGTAAAATATAGTT

Downstream 100 bases:

>100_bases
AATTAGTGGTACCAGTAGATTGTGGTTTGTTTACGGAAAACCAACAAATAATCCATTCGGAAGGGAAAAGGAAATAGAAT
CACTAATAAGACCAAATAAT

Product: agmatinase

Products: NA

Alternate protein names: GBase; D-arginase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MRQIDALKSPRFTQISTFGRLPICGRDEEIKAAFLGIPFDDAVTYRPGARFGPMGIRQGSRLLRPYNQFLDTYPFDKLNA
CDMGDINIIPGYIEDTMNIIQTNLYEIISSKNLVPFIAGGDHSITLPVLRALNKKYGKINIIHLDSHYDFWDSYWGKKHT
HGTWLRRAIEEGLIKEAIQGGIRASTFSKEDLKDKERLGVKSFTIRDLKYNLDSVIREINSLSGPTHVSIDIDVVDPAFA
PGTGTPEVGGLTSFEIIEIIRKLRFDKLVGFDVVEVAPPYDVSEITTMLAANIIYEGMSVLSLNL

Sequences:

>Translated_305_residues
MRQIDALKSPRFTQISTFGRLPICGRDEEIKAAFLGIPFDDAVTYRPGARFGPMGIRQGSRLLRPYNQFLDTYPFDKLNA
CDMGDINIIPGYIEDTMNIIQTNLYEIISSKNLVPFIAGGDHSITLPVLRALNKKYGKINIIHLDSHYDFWDSYWGKKHT
HGTWLRRAIEEGLIKEAIQGGIRASTFSKEDLKDKERLGVKSFTIRDLKYNLDSVIREINSLSGPTHVSIDIDVVDPAFA
PGTGTPEVGGLTSFEIIEIIRKLRFDKLVGFDVVEVAPPYDVSEITTMLAANIIYEGMSVLSLNL
>Mature_305_residues
MRQIDALKSPRFTQISTFGRLPICGRDEEIKAAFLGIPFDDAVTYRPGARFGPMGIRQGSRLLRPYNQFLDTYPFDKLNA
CDMGDINIIPGYIEDTMNIIQTNLYEIISSKNLVPFIAGGDHSITLPVLRALNKKYGKINIIHLDSHYDFWDSYWGKKHT
HGTWLRRAIEEGLIKEAIQGGIRASTFSKEDLKDKERLGVKSFTIRDLKYNLDSVIREINSLSGPTHVSIDIDVVDPAFA
PGTGTPEVGGLTSFEIIEIIRKLRFDKLVGFDVVEVAPPYDVSEITTMLAANIIYEGMSVLSLNL

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=302, Percent_Identity=38.7417218543046, Blast_Score=219, Evalue=3e-57,
Organism=Escherichia coli, GI1789306, Length=283, Percent_Identity=38.1625441696113, Blast_Score=160, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.7; =3.5.3.10 [H]

Molecular weight: Translated: 34231; Mature: 34231

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQIDALKSPRFTQISTFGRLPICGRDEEIKAAFLGIPFDDAVTYRPGARFGPMGIRQGS
CCCCCCCCCCCCEEHHCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCHHCCH
RLLRPYNQFLDTYPFDKLNACDMGDINIIPGYIEDTMNIIQTNLYEIISSKNLVPFIAGG
HHHHHHHHHHHCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
DHSITLPVLRALNKKYGKINIIHLDSHYDFWDSYWGKKHTHGTWLRRAIEEGLIKEAIQG
CCEEHHHHHHHHHHCCCEEEEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
GIRASTFSKEDLKDKERLGVKSFTIRDLKYNLDSVIREINSLSGPTHVSIDIDVVDPAFA
CCEECCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCC
PGTGTPEVGGLTSFEIIEIIRKLRFDKLVGFDVVEVAPPYDVSEITTMLAANIIYEGMSV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHCHHH
LSLNL
EEECC
>Mature Secondary Structure
MRQIDALKSPRFTQISTFGRLPICGRDEEIKAAFLGIPFDDAVTYRPGARFGPMGIRQGS
CCCCCCCCCCCCEEHHCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCHHCCH
RLLRPYNQFLDTYPFDKLNACDMGDINIIPGYIEDTMNIIQTNLYEIISSKNLVPFIAGG
HHHHHHHHHHHCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
DHSITLPVLRALNKKYGKINIIHLDSHYDFWDSYWGKKHTHGTWLRRAIEEGLIKEAIQG
CCEEHHHHHHHHHHCCCEEEEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
GIRASTFSKEDLKDKERLGVKSFTIRDLKYNLDSVIREINSLSGPTHVSIDIDVVDPAFA
CCEECCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCC
PGTGTPEVGGLTSFEIIEIIRKLRFDKLVGFDVVEVAPPYDVSEITTMLAANIIYEGMSV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHCHHH
LSLNL
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA