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The map label for this gene is appB [H]

Identifier: 227828638

GI number: 227828638

Start: 2220332

End: 2221393

Strand: Direct

Name: appB [H]

Synonym: M1425_2391

Alternate gene names: 227828638

Gene position: 2220332-2221393 (Clockwise)

Preceding gene: 227828637

Following gene: 227828639

Centisome position: 85.11

GC content: 35.4

Gene sequence:

>1062_bases
ATGATTTTTTATAAATTCTTGATTAAGAGAGCTATTGAGGCTTTCTTAGTAATAATGGCTGAACTTATTATAGTTTTTTA
TTTAGCCAATATCGCAGCTCCTAATCCAGCATCAGTTTGGGCGGGCCCAGAAGCCTCACCAGAACAAATCCAAATCGTAA
CTGAGCTTTATCATTTAAATCAACCCTGGTATATCCAGCTTTACTATTATTTAGGCAATTTCTTTACTGGAAAATGGGGA
ATATCACCATTATATCAAACCCCAGTTATATCATTGATAGAGGAATACTTACCAGTTACAATAGAATTAGCAATTATCGC
CTTAATCCTAAAGATAATTCTCGAAATATCACTAGGAATCTTATCCGCTTTGAAACCCAATGGTCTATTAGATAACTCAA
TAAGAGTAGTATATACTATAACAAGAAGTGCACCCCCATTTATAGTAGCATTATTATTACTCCTAATCCTTTCCTATTAC
TTTCACGTATTCCCTTCTTCATATTATATGAATCCAATCCTAGCCTTACATGAGAGCAAGTTTTACATTCAAATAGGAGG
GCATAAATATTATTTCTGGTTCATAGATAACATGCCAATTTTGAATTCATTACTTGTGGGTGATATTCCGGCTTTCGTAT
CTGCTTTAGATCATTCCATATTACCAGCTTTAGCCCTCACACTATTCGGCTTTGGAGGAATAGTTAGGCTCACTAGAAAC
TCAATGCTTGAAGTCTTAAATACGGACTATATAAAGACTGCTAGAGCTAAAGGTCTAAAAGAGAGAATAGTAATAACGAG
GCATGCGTTAAGGAATGCGCTACTATCCTCTATAACGCTTATAAGTGTAATTTTTGCTGGCCTAATGCAGGGAAGCTTAG
TAGTGGAGACCATTTTCAACTACTACGGAATTGGTTATTTAGTAGCTGAAAGCTTACTAAACTTAGATACACCAACGTTA
ATAGCAGCTACAGTTGTGATAACAATTGTAGTTGTAATATCGAATCTCGTCGCAGACATTTCCTATGCATTATTAGATCC
TAGGATAAGGGAAGCACTATGA

Upstream 100 bases:

>100_bases
TAGCATCGTCAAGTATTCATGGATTCTGGTATAGCCCCGGATTAGATGGGTTATTCTATGCTGACTTATACTGAAAAGAT
AGTGGGGTGTAAATTTCAAT

Downstream 100 bases:

>100_bases
ACCTAAAGGATATAACCAAAAATATGAACCTAACCGTAGGACTGATTATTATTCTCTCCTTCTTAGCCCTAACAATAATT
TCTACAGCTGATTTACACAT

Product: binding-protein-dependent transporters inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MIFYKFLIKRAIEAFLVIMAELIIVFYLANIAAPNPASVWAGPEASPEQIQIVTELYHLNQPWYIQLYYYLGNFFTGKWG
ISPLYQTPVISLIEEYLPVTIELAIIALILKIILEISLGILSALKPNGLLDNSIRVVYTITRSAPPFIVALLLLLILSYY
FHVFPSSYYMNPILALHESKFYIQIGGHKYYFWFIDNMPILNSLLVGDIPAFVSALDHSILPALALTLFGFGGIVRLTRN
SMLEVLNTDYIKTARAKGLKERIVITRHALRNALLSSITLISVIFAGLMQGSLVVETIFNYYGIGYLVAESLLNLDTPTL
IAATVVITIVVVISNLVADISYALLDPRIREAL

Sequences:

>Translated_353_residues
MIFYKFLIKRAIEAFLVIMAELIIVFYLANIAAPNPASVWAGPEASPEQIQIVTELYHLNQPWYIQLYYYLGNFFTGKWG
ISPLYQTPVISLIEEYLPVTIELAIIALILKIILEISLGILSALKPNGLLDNSIRVVYTITRSAPPFIVALLLLLILSYY
FHVFPSSYYMNPILALHESKFYIQIGGHKYYFWFIDNMPILNSLLVGDIPAFVSALDHSILPALALTLFGFGGIVRLTRN
SMLEVLNTDYIKTARAKGLKERIVITRHALRNALLSSITLISVIFAGLMQGSLVVETIFNYYGIGYLVAESLLNLDTPTL
IAATVVITIVVVISNLVADISYALLDPRIREAL
>Mature_353_residues
MIFYKFLIKRAIEAFLVIMAELIIVFYLANIAAPNPASVWAGPEASPEQIQIVTELYHLNQPWYIQLYYYLGNFFTGKWG
ISPLYQTPVISLIEEYLPVTIELAIIALILKIILEISLGILSALKPNGLLDNSIRVVYTITRSAPPFIVALLLLLILSYY
FHVFPSSYYMNPILALHESKFYIQIGGHKYYFWFIDNMPILNSLLVGDIPAFVSALDHSILPALALTLFGFGGIVRLTRN
SMLEVLNTDYIKTARAKGLKERIVITRHALRNALLSSITLISVIFAGLMQGSLVVETIFNYYGIGYLVAESLLNLDTPTL
IAATVVITIVVVISNLVADISYALLDPRIREAL

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787761, Length=354, Percent_Identity=33.0508474576271, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1789965, Length=352, Percent_Identity=29.8295454545455, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1787497, Length=348, Percent_Identity=31.6091954022989, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787053, Length=346, Percent_Identity=28.0346820809249, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1789888, Length=350, Percent_Identity=27.4285714285714, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1788504, Length=316, Percent_Identity=29.1139240506329, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1787550, Length=279, Percent_Identity=26.1648745519713, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 39524; Mature: 39524

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFYKFLIKRAIEAFLVIMAELIIVFYLANIAAPNPASVWAGPEASPEQIQIVTELYHLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
QPWYIQLYYYLGNFFTGKWGISPLYQTPVISLIEEYLPVTIELAIIALILKIILEISLGI
CCCEEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LSALKPNGLLDNSIRVVYTITRSAPPFIVALLLLLILSYYFHVFPSSYYMNPILALHESK
HHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHCHHHEEECCE
FYIQIGGHKYYFWFIDNMPILNSLLVGDIPAFVSALDHSILPALALTLFGFGGIVRLTRN
EEEEECCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SMLEVLNTDYIKTARAKGLKERIVITRHALRNALLSSITLISVIFAGLMQGSLVVETIFN
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
YYGIGYLVAESLLNLDTPTLIAATVVITIVVVISNLVADISYALLDPRIREAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure
MIFYKFLIKRAIEAFLVIMAELIIVFYLANIAAPNPASVWAGPEASPEQIQIVTELYHLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
QPWYIQLYYYLGNFFTGKWGISPLYQTPVISLIEEYLPVTIELAIIALILKIILEISLGI
CCCEEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LSALKPNGLLDNSIRVVYTITRSAPPFIVALLLLLILSYYFHVFPSSYYMNPILALHESK
HHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHCHHHEEECCE
FYIQIGGHKYYFWFIDNMPILNSLLVGDIPAFVSALDHSILPALALTLFGFGGIVRLTRN
EEEEECCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SMLEVLNTDYIKTARAKGLKERIVITRHALRNALLSSITLISVIFAGLMQGSLVVETIFN
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
YYGIGYLVAESLLNLDTPTLIAATVVITIVVVISNLVADISYALLDPRIREAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]