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The map label for this gene is mntH [H]

Identifier: 227828605

GI number: 227828605

Start: 2190696

End: 2191880

Strand: Direct

Name: mntH [H]

Synonym: M1425_2358

Alternate gene names: 227828605

Gene position: 2190696-2191880 (Clockwise)

Preceding gene: 227828603

Following gene: 227828608

Centisome position: 83.97

GC content: 36.37

Gene sequence:

>1185_bases
ATGAGCATTAGAGAGATAGTAAGACTTTTCGGTCCAGCATGGATAGTAATGATGGCGGATGTTGACGCAGCAAGCGTATT
AACTGGCGTAGCCAATGGGCAAGAGTACGGATATAGAATGATCTGGCTGTTGCTACTCTTAGCCTTTCCCTTATATGTTA
TCCAAGAAGCTGCCGGAAGATTAGGTGCAGTAAATAATGGTAAAGGTCTTGGGGAGATTATTAGGGAGAGATACTCAGTT
AAAATATCGCTACTAGCCTCTCTTTCTATGTTCATGGTTGACGTGTTCACGTACATAGTTGAATACGTTGGAATAGCAGT
CGGGGGATTAGTGCTAGGAGTTCCACCTTATATAACTCTTCCAATTTTCTTTATATTTCATCTAATTATAATATCAACTA
GAAAATATGATAAAATAGAGAAATTCCTAATACCGATATCTTTAATTTTGATAGTTGCATTTATGCTTGAAGCTATATTA
AGGGGCATCATACCTGGAGAAAACGTATTTTACTTCTCACTTTCCAAATCCTTTACGTTTCTTGTTGCTGCAAATATAGG
CGCAGTAGTCATGCCCTTTATGATATTTTACCAAACCTCGGCAACTGCTTATAAATACCAAGATGTAGCTTCGCCAATAG
AAACTAAGGTGAAGTGGTCCTCCATAGAGACGTTTATCGGGGCCATAGTATCAGAGCTTATAATGGTGGCTATAGAAATG
GCAACTACTGGAATTTCACCATCAGTAGATCCTTTAAATTACAAGGAAATGTCTTATTCACTATCCTTAATTTCAGGTCC
AATTTCCCCATATATATTTGGAATTGGCTTAATTAGTGCAGCTTTTCTGGCATTAATAGTGGAGTCTTTAGGAAGTGCGT
GGGGAACTTTAGAAGCTTTAGGTAAAAACACTTTTAGCAACTTTCTACTATTATATATTTCGGAGTCGATTCCTGCACTC
GCAATTACGCTACTTTTCACCAACAATTACGATAATGTGATAAACTTTGCCCTAACTTTAATGTCAATAGCACCATTTAT
AGTTATAATCCCCTCGGTATTGATTGGAATTTTAATAAAGGATAAGAACTTAATGATGAACTACAAATATGGAAGAACTA
GAATAATCATTTATTGGATTACCGTTATAATTATACTCACTGGGGGAATACTTGCAATAATTTAG

Upstream 100 bases:

>100_bases
TTTTAAGAATTTAAAGTGAAGCTTTATTCCATCATTAATAAATATATACATTTACGATTAGGCGTAAAGCATATATATAC
TGAACATTGTGTATCATAAT

Downstream 100 bases:

>100_bases
GTTCCTTTCCACATTTTTAAGGAGGATATGAAATCTGAAATTGAATATCTACTCTTCCAGCTTAATGGATAACTAAACTT
AATATAGCGAGGGGAAGTGT

Product: manganese transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MSIREIVRLFGPAWIVMMADVDAASVLTGVANGQEYGYRMIWLLLLLAFPLYVIQEAAGRLGAVNNGKGLGEIIRERYSV
KISLLASLSMFMVDVFTYIVEYVGIAVGGLVLGVPPYITLPIFFIFHLIIISTRKYDKIEKFLIPISLILIVAFMLEAIL
RGIIPGENVFYFSLSKSFTFLVAANIGAVVMPFMIFYQTSATAYKYQDVASPIETKVKWSSIETFIGAIVSELIMVAIEM
ATTGISPSVDPLNYKEMSYSLSLISGPISPYIFGIGLISAAFLALIVESLGSAWGTLEALGKNTFSNFLLLYISESIPAL
AITLLFTNNYDNVINFALTLMSIAPFIVIIPSVLIGILIKDKNLMMNYKYGRTRIIIYWITVIIILTGGILAII

Sequences:

>Translated_394_residues
MSIREIVRLFGPAWIVMMADVDAASVLTGVANGQEYGYRMIWLLLLLAFPLYVIQEAAGRLGAVNNGKGLGEIIRERYSV
KISLLASLSMFMVDVFTYIVEYVGIAVGGLVLGVPPYITLPIFFIFHLIIISTRKYDKIEKFLIPISLILIVAFMLEAIL
RGIIPGENVFYFSLSKSFTFLVAANIGAVVMPFMIFYQTSATAYKYQDVASPIETKVKWSSIETFIGAIVSELIMVAIEM
ATTGISPSVDPLNYKEMSYSLSLISGPISPYIFGIGLISAAFLALIVESLGSAWGTLEALGKNTFSNFLLLYISESIPAL
AITLLFTNNYDNVINFALTLMSIAPFIVIIPSVLIGILIKDKNLMMNYKYGRTRIIIYWITVIIILTGGILAII
>Mature_393_residues
SIREIVRLFGPAWIVMMADVDAASVLTGVANGQEYGYRMIWLLLLLAFPLYVIQEAAGRLGAVNNGKGLGEIIRERYSVK
ISLLASLSMFMVDVFTYIVEYVGIAVGGLVLGVPPYITLPIFFIFHLIIISTRKYDKIEKFLIPISLILIVAFMLEAILR
GIIPGENVFYFSLSKSFTFLVAANIGAVVMPFMIFYQTSATAYKYQDVASPIETKVKWSSIETFIGAIVSELIMVAIEMA
TTGISPSVDPLNYKEMSYSLSLISGPISPYIFGIGLISAAFLALIVESLGSAWGTLEALGKNTFSNFLLLYISESIPALA
ITLLFTNNYDNVINFALTLMSIAPFIVIIPSVLIGILIKDKNLMMNYKYGRTRIIIYWITVIIILTGGILAII

Specific function: H(+)-stimulated, highly selective, manganese uptake system. Can probably also transport cadmium, cobalt, copper and zinc, but not iron. May be the predominant transporter of manganese during logarithmic phase growth [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Escherichia coli, GI1788736, Length=292, Percent_Identity=25, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 43414; Mature: 43282

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIREIVRLFGPAWIVMMADVDAASVLTGVANGQEYGYRMIWLLLLLAFPLYVIQEAAGR
CCHHHHHHHHCCHHEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGAVNNGKGLGEIIRERYSVKISLLASLSMFMVDVFTYIVEYVGIAVGGLVLGVPPYITL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
PIFFIFHLIIISTRKYDKIEKFLIPISLILIVAFMLEAILRGIIPGENVFYFSLSKSFTF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEE
LVAANIGAVVMPFMIFYQTSATAYKYQDVASPIETKVKWSSIETFIGAIVSELIMVAIEM
EEECCCHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATTGISPSVDPLNYKEMSYSLSLISGPISPYIFGIGLISAAFLALIVESLGSAWGTLEAL
HHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GKNTFSNFLLLYISESIPALAITLLFTNNYDNVINFALTLMSIAPFIVIIPSVLIGILIK
HHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DKNLMMNYKYGRTRIIIYWITVIIILTGGILAII
CCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIREIVRLFGPAWIVMMADVDAASVLTGVANGQEYGYRMIWLLLLLAFPLYVIQEAAGR
CHHHHHHHHCCHHEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGAVNNGKGLGEIIRERYSVKISLLASLSMFMVDVFTYIVEYVGIAVGGLVLGVPPYITL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
PIFFIFHLIIISTRKYDKIEKFLIPISLILIVAFMLEAILRGIIPGENVFYFSLSKSFTF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEE
LVAANIGAVVMPFMIFYQTSATAYKYQDVASPIETKVKWSSIETFIGAIVSELIMVAIEM
EEECCCHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATTGISPSVDPLNYKEMSYSLSLISGPISPYIFGIGLISAAFLALIVESLGSAWGTLEAL
HHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GKNTFSNFLLLYISESIPALAITLLFTNNYDNVINFALTLMSIAPFIVIIPSVLIGILIK
HHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DKNLMMNYKYGRTRIIIYWITVIIILTGGILAII
CCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 10760146 [H]