Click here to switch to the map view.

The map label for this gene is lutB [H]

Identifier: 227828488

GI number: 227828488

Start: 2044142

End: 2045293

Strand: Direct

Name: lutB [H]

Synonym: M1425_2237

Alternate gene names: 227828488

Gene position: 2044142-2045293 (Clockwise)

Preceding gene: 227828487

Following gene: 227828490

Centisome position: 78.35

GC content: 42.01

Gene sequence:

>1152_bases
GTGAGTGATTGGGATATTGCAATAAAGAGGGGAGTAGAGCATAACGTTCCTAGGGTATTTAAGGTATTAAGGGAACATCC
ATATTTAGAAGATTTAGCAAGGAAGGTCAGAGAGGGAAAATTAGAGGTTCTTAGTAATTTAGACCACTACATAGATATGA
CCATGAAATCTGTAGAGAGGATTGGGGGTAAGGCGTATTTCGTGGAAAACGCTGAGCAAGCCAAGGAGATTGTTGGTAAA
ATTGTAGGTTGTGGTAAGAGGGTTGTTATGGGGAAGTCAATGGTTGCATATGAAACGGGAATTAGGAAGTATTTGCAGTC
CATAGGAAATGAGGTTTGGGAGACTGACTTAGGTGAACTACTTATACAATTCGCTGATGAGCCTCCATCACATATAATTG
CCCCCGCAGTCCACATGACTAGGGAGAGAATAAGGGAGTTGATAAAGGAGAAGTTAGGTATAGATCCGGGAGATAAACAT
GAGGATATTGTGAGAGTTGCTAGGGAGTTTTTAAGGCAGAAGTTCTTGACAGCTGACATAGGAATTACTGGAGCTAATGC
AGTAGCTGCAGATGCAGGTTCTATTGTTTTAGTCGAGAATGAGGGCAATATAAGGATGAGTAGCGTAGTTCCCCCAGTCC
ACATTTCCATTACTGGTGTGGAGAAGATTTTGCCGAACCTGGAGTACGCAATGTATGAGGTTTTAGTTCAAGCAGCCTAC
GCTGGTTTATATCCTCCAACTTATATAAACGTTACTTCTGGTCCTTCATCAACTGGTGATGTTGAGCAAAAGAGGGTATC
TCCAGCTCACGGTCCAAAGGAGTTTCACCTAATTTTAGTAGATAATGGTAGGAGAAAGGCTAATGAGGATCCGGTATTGA
GAGAGGCGTTACTCTGTATAAGGTGTGGTAGATGTCATTTCCATTGTCCAGTTTATAGGGCTTTAGATGGTAAATGGGGA
GATCCTCCCTATTCTGGCCCAATGGGCGCAATGTGGAGTGGTGTAGTTTATAATGATTATAAGCCTGCTTTGCTTTGCTC
TCATGCTGGTAACTGTAGGGAGGTATGTCCTATGAAAATAAATATTCCTAAAGTGTTGGAATATTTGAAAAGCAAGTTCT
TTATGATGAAGGCTGGGACAAGGGAGGGATGA

Upstream 100 bases:

>100_bases
CTAAAGAGTGTTCACAATAAAGTTCTCTTAGCTTGTCCATTTTGTTACGCTAATCTTTCTCCTTATGTAGAAGCTTACGA
TTTCGCTGAGGTGATAAGTG

Downstream 100 bases:

>100_bases
CGAGAAATATAGGTTATCTTGCTGATTATTCTTGTGATACCATAGTCCCTCTTATTTTTATATCTCTTGTCATGCTCCCT
ATTATGACCATCAGTAAGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MSDWDIAIKRGVEHNVPRVFKVLREHPYLEDLARKVREGKLEVLSNLDHYIDMTMKSVERIGGKAYFVENAEQAKEIVGK
IVGCGKRVVMGKSMVAYETGIRKYLQSIGNEVWETDLGELLIQFADEPPSHIIAPAVHMTRERIRELIKEKLGIDPGDKH
EDIVRVAREFLRQKFLTADIGITGANAVAADAGSIVLVENEGNIRMSSVVPPVHISITGVEKILPNLEYAMYEVLVQAAY
AGLYPPTYINVTSGPSSTGDVEQKRVSPAHGPKEFHLILVDNGRRKANEDPVLREALLCIRCGRCHFHCPVYRALDGKWG
DPPYSGPMGAMWSGVVYNDYKPALLCSHAGNCREVCPMKINIPKVLEYLKSKFFMMKAGTREG

Sequences:

>Translated_383_residues
MSDWDIAIKRGVEHNVPRVFKVLREHPYLEDLARKVREGKLEVLSNLDHYIDMTMKSVERIGGKAYFVENAEQAKEIVGK
IVGCGKRVVMGKSMVAYETGIRKYLQSIGNEVWETDLGELLIQFADEPPSHIIAPAVHMTRERIRELIKEKLGIDPGDKH
EDIVRVAREFLRQKFLTADIGITGANAVAADAGSIVLVENEGNIRMSSVVPPVHISITGVEKILPNLEYAMYEVLVQAAY
AGLYPPTYINVTSGPSSTGDVEQKRVSPAHGPKEFHLILVDNGRRKANEDPVLREALLCIRCGRCHFHCPVYRALDGKWG
DPPYSGPMGAMWSGVVYNDYKPALLCSHAGNCREVCPMKINIPKVLEYLKSKFFMMKAGTREG
>Mature_382_residues
SDWDIAIKRGVEHNVPRVFKVLREHPYLEDLARKVREGKLEVLSNLDHYIDMTMKSVERIGGKAYFVENAEQAKEIVGKI
VGCGKRVVMGKSMVAYETGIRKYLQSIGNEVWETDLGELLIQFADEPPSHIIAPAVHMTRERIRELIKEKLGIDPGDKHE
DIVRVAREFLRQKFLTADIGITGANAVAADAGSIVLVENEGNIRMSSVVPPVHISITGVEKILPNLEYAMYEVLVQAAYA
GLYPPTYINVTSGPSSTGDVEQKRVSPAHGPKEFHLILVDNGRRKANEDPVLREALLCIRCGRCHFHCPVYRALDGKWGD
PPYSGPMGAMWSGVVYNDYKPALLCSHAGNCREVCPMKINIPKVLEYLKSKFFMMKAGTREG

Specific function: Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofi

COG id: COG1139

COG function: function code C; Uncharacterized conserved protein containing a ferredoxin-like domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1786498, Length=367, Percent_Identity=35.9673024523161, Blast_Score=224, Evalue=8e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017900
- InterPro:   IPR003741
- InterPro:   IPR004452
- InterPro:   IPR002698
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR022825 [H]

Pfam domain/function: PF02589 DUF162 [H]

EC number: NA

Molecular weight: Translated: 42771; Mature: 42640

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDWDIAIKRGVEHNVPRVFKVLREHPYLEDLARKVREGKLEVLSNLDHYIDMTMKSVER
CCCHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGGKAYFVENAEQAKEIVGKIVGCGKRVVMGKSMVAYETGIRKYLQSIGNEVWETDLGEL
HCCCEEEECCHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIQFADEPPSHIIAPAVHMTRERIRELIKEKLGIDPGDKHEDIVRVAREFLRQKFLTADI
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCC
GITGANAVAADAGSIVLVENEGNIRMSSVVPPVHISITGVEKILPNLEYAMYEVLVQAAY
CCCCCCHHCCCCCCEEEEECCCCEEEECCCCCEEEEECCHHHHHCCHHHHHHHHHHHHHH
AGLYPPTYINVTSGPSSTGDVEQKRVSPAHGPKEFHLILVDNGRRKANEDPVLREALLCI
HCCCCCCEEEECCCCCCCCCCHHHHCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHH
RCGRCHFHCPVYRALDGKWGDPPYSGPMGAMWSGVVYNDYKPALLCSHAGNCREVCPMKI
HCCCEEECCCHHHHCCCCCCCCCCCCCCHHHHCCCEECCCCCEEEECCCCCCHHCCCCEE
NIPKVLEYLKSKFFMMKAGTREG
CHHHHHHHHHHHEEEEECCCCCC
>Mature Secondary Structure 
SDWDIAIKRGVEHNVPRVFKVLREHPYLEDLARKVREGKLEVLSNLDHYIDMTMKSVER
CCHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGGKAYFVENAEQAKEIVGKIVGCGKRVVMGKSMVAYETGIRKYLQSIGNEVWETDLGEL
HCCCEEEECCHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIQFADEPPSHIIAPAVHMTRERIRELIKEKLGIDPGDKHEDIVRVAREFLRQKFLTADI
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCC
GITGANAVAADAGSIVLVENEGNIRMSSVVPPVHISITGVEKILPNLEYAMYEVLVQAAY
CCCCCCHHCCCCCCEEEEECCCCEEEECCCCCEEEEECCHHHHHCCHHHHHHHHHHHHHH
AGLYPPTYINVTSGPSSTGDVEQKRVSPAHGPKEFHLILVDNGRRKANEDPVLREALLCI
HCCCCCCEEEECCCCCCCCCCHHHHCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHH
RCGRCHFHCPVYRALDGKWGDPPYSGPMGAMWSGVVYNDYKPALLCSHAGNCREVCPMKI
HCCCEEECCCHHHHCCCCCCCCCCCCCCHHHHCCCEECCCCCEEEECCCCCCHHCCCCEE
NIPKVLEYLKSKFFMMKAGTREG
CHHHHHHHHHHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]