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The map label for this gene is yyaJ [H]

Identifier: 227828476

GI number: 227828476

Start: 2033694

End: 2035040

Strand: Direct

Name: yyaJ [H]

Synonym: M1425_2224

Alternate gene names: 227828476

Gene position: 2033694-2035040 (Clockwise)

Preceding gene: 227828474

Following gene: 227828478

Centisome position: 77.95

GC content: 37.79

Gene sequence:

>1347_bases
ATGAGTATCGCTGGGAGAATAGAAAGACTACCTTGGACTTCTTTTCATACGAGACTCTTAGCCCTCTTAACTCTGGGAGA
GTTCTTCGAGCTCTACGATCTATTTACTGGAGGCTTCGTAGCATCACAAGTGGCATCGTTTTTTAAAGTATCATCAGCAA
CTGGAATCTACTATACTGTTGCAATCTTCTTTCTAGGAGCATTCGTAGGTGCGATAATTTTCAACTATATAGGAGATTCA
GTAGGTAGGAGGACTGCACTGATAATCAACATGGCAATAACCTCTATCGCCTTACTGTTGATACCATTTTCTCCAAATAT
TCTAACTTTTGGAATATTAAGATTTATAGCTGGTGTAGGAGTTGGACCAGAGGCAATATTAGTTTTAGACGTTTTAATAA
CGGAGTTCTTTCCGTCGACTGTCAGAGGTAGGGCGTTAGCAATAGGTTATACTGCAGCTTGGACTGCACCTATAGTCGTC
GCAATTCTAGCTTATCTTCTTCTGCCTCATAAATACATTCTATACGGTTGGCAATGGTTATTCATAATAGGAGGCTTAGG
TATACTTACAATAATACCATTTAGATTCCTAATTCCAGAATCTCCTAGATGGTTAGAAAGTAAGGGAAGATTGGATGAGG
CTGAAAAAATAGTTAGAAGGATGGAGGAAATAGCTATTAAGGAAAAGGGGCAATTGGGAGAACCATTACAGGTCCAAGTT
ATAACTTCACAAAGGGTTACAATATCTGAATTATTCTCACCACTGTATAGAAAGAGGACAATAATGCTATGGGTTTTTGA
ATTCTTACAAGCTGGCGTATATTACGGTTTTGCCTCACTGGCCCCATCAGTGCTATTTGCGAAAGGTTTCACATTAGTAC
ATACTCTACAGTACACGATGATAATCTATACCTCATACTTTATTAGTTCTCTAGCATCAATATTTATCATAGATAGTCAA
AAGTTTGACAGAAAATGGCAGGTAAGTATTGTAATGTTATTAATGGGGTTAGTAGGACTAGCTTTTGGATTCTCCTCCTC
TCCTCTGGAGGCAGTAGCAACTGGCTTCACATTTGGTTTCTTGTCAAATATATTTTCCAATGCTTTCCATCAATACGGCG
CTGAGCTATATCCAACTAGAGTAAGGGCTTTTGCAGATGGTGTACAGTACTCATTAAGTAGATTAGGAAACTACATTTGG
TTAACTCTCTTACCAATAGTGTTATATAGTAACGGACCAATTGCAATGTACACAGTGGTATTCATAATGGCTCTTATAGT
AACTCTAGATGTGGCAATTTTAGGACCTAAAGCTTCAAAGATTGAACTTGAAGAATTATCAAAATAA

Upstream 100 bases:

>100_bases
TCTTACGTTAAAAAGTAGAAGATAAATAAGATTATTTGCATAAAATTTCGAACATCTCCCCTTTGCAAAATTTATTAGTT
TATTTAATTTATAAACACAT

Downstream 100 bases:

>100_bases
ATAATTAAAAAAGTTTATAATTTTTGTTATACTAAAACGTATGTATTGTAACCTTGTTCCGGTATGTAGTATATTTGGGG
ATATTTATTATTACCTTGAC

Product: major facilitator superfamily MFS_1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MSIAGRIERLPWTSFHTRLLALLTLGEFFELYDLFTGGFVASQVASFFKVSSATGIYYTVAIFFLGAFVGAIIFNYIGDS
VGRRTALIINMAITSIALLLIPFSPNILTFGILRFIAGVGVGPEAILVLDVLITEFFPSTVRGRALAIGYTAAWTAPIVV
AILAYLLLPHKYILYGWQWLFIIGGLGILTIIPFRFLIPESPRWLESKGRLDEAEKIVRRMEEIAIKEKGQLGEPLQVQV
ITSQRVTISELFSPLYRKRTIMLWVFEFLQAGVYYGFASLAPSVLFAKGFTLVHTLQYTMIIYTSYFISSLASIFIIDSQ
KFDRKWQVSIVMLLMGLVGLAFGFSSSPLEAVATGFTFGFLSNIFSNAFHQYGAELYPTRVRAFADGVQYSLSRLGNYIW
LTLLPIVLYSNGPIAMYTVVFIMALIVTLDVAILGPKASKIELEELSK

Sequences:

>Translated_448_residues
MSIAGRIERLPWTSFHTRLLALLTLGEFFELYDLFTGGFVASQVASFFKVSSATGIYYTVAIFFLGAFVGAIIFNYIGDS
VGRRTALIINMAITSIALLLIPFSPNILTFGILRFIAGVGVGPEAILVLDVLITEFFPSTVRGRALAIGYTAAWTAPIVV
AILAYLLLPHKYILYGWQWLFIIGGLGILTIIPFRFLIPESPRWLESKGRLDEAEKIVRRMEEIAIKEKGQLGEPLQVQV
ITSQRVTISELFSPLYRKRTIMLWVFEFLQAGVYYGFASLAPSVLFAKGFTLVHTLQYTMIIYTSYFISSLASIFIIDSQ
KFDRKWQVSIVMLLMGLVGLAFGFSSSPLEAVATGFTFGFLSNIFSNAFHQYGAELYPTRVRAFADGVQYSLSRLGNYIW
LTLLPIVLYSNGPIAMYTVVFIMALIVTLDVAILGPKASKIELEELSK
>Mature_447_residues
SIAGRIERLPWTSFHTRLLALLTLGEFFELYDLFTGGFVASQVASFFKVSSATGIYYTVAIFFLGAFVGAIIFNYIGDSV
GRRTALIINMAITSIALLLIPFSPNILTFGILRFIAGVGVGPEAILVLDVLITEFFPSTVRGRALAIGYTAAWTAPIVVA
ILAYLLLPHKYILYGWQWLFIIGGLGILTIIPFRFLIPESPRWLESKGRLDEAEKIVRRMEEIAIKEKGQLGEPLQVQVI
TSQRVTISELFSPLYRKRTIMLWVFEFLQAGVYYGFASLAPSVLFAKGFTLVHTLQYTMIIYTSYFISSLASIFIIDSQK
FDRKWQVSIVMLLMGLVGLAFGFSSSPLEAVATGFTFGFLSNIFSNAFHQYGAELYPTRVRAFADGVQYSLSRLGNYIWL
TLLPIVLYSNGPIAMYTVVFIMALIVTLDVAILGPKASKIELEELSK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI166197673, Length=369, Percent_Identity=30.0813008130081, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI213021148, Length=428, Percent_Identity=23.8317757009346, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI4507005, Length=352, Percent_Identity=26.9886363636364, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4506999, Length=410, Percent_Identity=27.5609756097561, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI24308167, Length=420, Percent_Identity=23.5714285714286, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI302148518, Length=351, Percent_Identity=25.9259259259259, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI166064021, Length=374, Percent_Identity=25.4010695187166, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI23510410, Length=219, Percent_Identity=30.5936073059361, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI24497476, Length=386, Percent_Identity=24.0932642487047, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI20070188, Length=386, Percent_Identity=24.0932642487047, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI24497490, Length=359, Percent_Identity=27.5766016713092, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI216548223, Length=264, Percent_Identity=23.8636363636364, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI262399383, Length=265, Percent_Identity=24.9056603773585, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI7662270, Length=265, Percent_Identity=24.9056603773585, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI24497478, Length=339, Percent_Identity=24.188790560472, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI24497480, Length=339, Percent_Identity=24.188790560472, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI148664184, Length=395, Percent_Identity=24.3037974683544, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI73695465, Length=200, Percent_Identity=26, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1788074, Length=406, Percent_Identity=28.3251231527094, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1788068, Length=457, Percent_Identity=25.8205689277899, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786229, Length=423, Percent_Identity=26.9503546099291, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082159, Length=414, Percent_Identity=27.2946859903382, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789312, Length=424, Percent_Identity=21.2264150943396, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789207, Length=424, Percent_Identity=23.1132075471698, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1790463, Length=335, Percent_Identity=25.0746268656716, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI25145172, Length=384, Percent_Identity=24.21875, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32564663, Length=450, Percent_Identity=22, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71986689, Length=379, Percent_Identity=21.8997361477573, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193202825, Length=378, Percent_Identity=21.957671957672, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193209133, Length=432, Percent_Identity=22.9166666666667, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322242, Length=336, Percent_Identity=25.8928571428571, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324417, Length=336, Percent_Identity=25.8928571428571, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI221330907, Length=345, Percent_Identity=28.4057971014493, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI21355657, Length=345, Percent_Identity=25.2173913043478, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648211, Length=349, Percent_Identity=26.3610315186246, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24649618, Length=233, Percent_Identity=26.6094420600858, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24640198, Length=221, Percent_Identity=28.0542986425339, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640196, Length=221, Percent_Identity=28.0542986425339, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640200, Length=221, Percent_Identity=28.0542986425339, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24585484, Length=386, Percent_Identity=24.3523316062176, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI20129657, Length=386, Percent_Identity=24.3523316062176, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24649616, Length=251, Percent_Identity=24.7011952191235, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24658792, Length=388, Percent_Identity=22.1649484536082, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 49906; Mature: 49774

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIAGRIERLPWTSFHTRLLALLTLGEFFELYDLFTGGFVASQVASFFKVSSATGIYYTV
CCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHH
AIFFLGAFVGAIIFNYIGDSVGRRTALIINMAITSIALLLIPFSPNILTFGILRFIAGVG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
VGPEAILVLDVLITEFFPSTVRGRALAIGYTAAWTAPIVVAILAYLLLPHKYILYGWQWL
CCHHHHHHHHHHHHHHCCHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FIIGGLGILTIIPFRFLIPESPRWLESKGRLDEAEKIVRRMEEIAIKEKGQLGEPLQVQV
HHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEE
ITSQRVTISELFSPLYRKRTIMLWVFEFLQAGVYYGFASLAPSVLFAKGFTLVHTLQYTM
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
IIYTSYFISSLASIFIIDSQKFDRKWQVSIVMLLMGLVGLAFGFSSSPLEAVATGFTFGF
HHHHHHHHHHHHHEEEECCHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LSNIFSNAFHQYGAELYPTRVRAFADGVQYSLSRLGNYIWLTLLPIVLYSNGPIAMYTVV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
FIMALIVTLDVAILGPKASKIELEELSK
HHHHHHHHHHHHHCCCCCCCCCHHHCCC
>Mature Secondary Structure 
SIAGRIERLPWTSFHTRLLALLTLGEFFELYDLFTGGFVASQVASFFKVSSATGIYYTV
CCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHH
AIFFLGAFVGAIIFNYIGDSVGRRTALIINMAITSIALLLIPFSPNILTFGILRFIAGVG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
VGPEAILVLDVLITEFFPSTVRGRALAIGYTAAWTAPIVVAILAYLLLPHKYILYGWQWL
CCHHHHHHHHHHHHHHCCHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FIIGGLGILTIIPFRFLIPESPRWLESKGRLDEAEKIVRRMEEIAIKEKGQLGEPLQVQV
HHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEE
ITSQRVTISELFSPLYRKRTIMLWVFEFLQAGVYYGFASLAPSVLFAKGFTLVHTLQYTM
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
IIYTSYFISSLASIFIIDSQKFDRKWQVSIVMLLMGLVGLAFGFSSSPLEAVATGFTFGF
HHHHHHHHHHHHHEEEECCHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LSNIFSNAFHQYGAELYPTRVRAFADGVQYSLSRLGNYIWLTLLPIVLYSNGPIAMYTVV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
FIMALIVTLDVAILGPKASKIELEELSK
HHHHHHHHHHHHHCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]