Click here to switch to the map view.

The map label for this gene is eriC [C]

Identifier: 227828415

GI number: 227828415

Start: 1978539

End: 1980287

Strand: Direct

Name: eriC [C]

Synonym: M1425_2158

Alternate gene names: 227828415

Gene position: 1978539-1980287 (Clockwise)

Preceding gene: 227828413

Following gene: 227828416

Centisome position: 75.84

GC content: 38.59

Gene sequence:

>1749_bases
ATGAACTTATCCTCATTACCTTATTTCGAGAAGTGGTTCATCCTTGGAATATTTTTAGGTGTTGTAGCAGGATTGGCTGC
GACTACATTTTATTTGTTATTACACTTGTTCGAAGATATATTTCTGTTTCATTTTATTGGAATGAGTTATCCTAGACCGC
TTGGCGAGGGAGGAACATTAAATTTCATCTTTCATCCTGGAAATTATCTTCTTATACCCATATCTACTGCAATTGGAGGA
TTAATTTCTGGAATAATAGTCTACACATTCGCTCCGGAAGCTGAGGGACATGGTACAGATGCTGCAATAAAGGCCTATCA
TTATTTTCAAGGCAAGATTAGATGGGTAGTTATCCCAGTTAAGATAATAGCTTCAGCAATTACTATAGGTTCTGGTGGTA
GTGCAGGAAGAGAAGGCCCAACTGCGCAATTTTCAGCTGGCGTAGGTTCAGTTATTGCTGATTTACTCCATCTCAGTCCA
GAGGATAGGAGAAGGGCCTTAGCAGTAGGGATTGGAGCTGGAATAGGTACAATTTTTAAAACACCAATTGGAGGTGCAAT
CTTGGCAGCTGAAATCCTATATAGAAGGGATCTAGAGCCAGAAGTAATATATCCTGCATTAGTAGCTTCAGCAATAGGTT
ATACTATATTCGGAAGCATATTTGGTTTCACTCCAGTATTTGGTTATTATACTGGTACTTTTGATCCGCTCAGATTGCCA
ATGTATGCGGTCCTAGGACTAGTTTCTGGTTTGATGGCAATACTATATCCTAAAACCTTCTATGGAGTTAATTCACTTTT
CAAAAAATTACGAATACCTAATCATGTAAAGCCAGCAATAGGTGGACTTATTACTGGTTTAATTGCATTATTGGCCCCAG
AGATTCTTGGAACAGGTTATGGCTGGATTAACTTGGTTGAGTATGAAAAGTTTTTCACATTATATTCTCCGCTTATCCCT
ACAATCATATTATTAGTAATATTACCGTTTTTAAAGATTTTAGGCACTTCGTTTTCTATAGGTTCTGGAGGTAGTGGTGG
AGTTTTTGCTCCCGGTTTATTTATAGGGGCATATATAGGTGCAAGTGTCGGGTTATTGTTCCATTACTTATTCCCAAACA
TTGTACCTACCATAGCCCCATTTGCTATCATTGGCATGATGAGCTTCTTTGCAGGTGCAGGGAAGGTTCCATTATCAGTT
TTAATAATGGTTACTGAAATGACCTCAAGTCTCCAATTACTGCCTGGAGCCATGATTGCCGTAGCAATTTCCTATTTAGT
TTCCGGAAACAATACGATATATATTTCTCAATTGCCAACCAGAAGAGACTCTCCAGCTCACAAAGCTGAATATGAAACTC
CATTAATGGAGACCGTACGTGTGGAAAAGTGTGAATTGAGAGATATTAAGGCTTACACTGATGATAAAGTAGGAAAGGCT
ATACAAATAATGCTTGAGAATAATTTCATGAGCCTACCCGTGGTAAATTACGATAATAGGTTTCTTGGAGTAGTGTATCT
AAGAGATTTGGAAAGGGCTAATCCTGAAGACTCGCTGGGAAAATATATAACCAGAGGTTCTCCTTCAGTATCCTTAACCT
CCACATTGGAACATGCGTTGGAGGTAATGGCTACTAACAAAGCTAGATGGGTTGCGGTTGTGGATAAGGGGAAACTTTTA
GGAATTGTTACATACGATGGTATTATAGACGCGTATAAGAGAGAGTTAAACGCGATTAAGAATTCATGA

Upstream 100 bases:

>100_bases
TTGAATGTAATTATAGACTTAAAAAACGTAGATTGAGAATAATGGTATTCATTCCATAATTAGACAAATTTTTTAATTCG
TATCCATTCTACATTACTGT

Downstream 100 bases:

>100_bases
CTAAATATCTCTAACACAATTTTTTAAACGTAGTTTTGCAACAATAATTATGGAAGAAGTTCAGAAACCACCAAATCAAA
AATATATAAAGAATTTTATT

Product: chloride channel core

Products: Cl Ion [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 582; Mature: 582

Protein sequence:

>582_residues
MNLSSLPYFEKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTLNFIFHPGNYLLIPISTAIGG
LISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKIRWVVIPVKIIASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSP
EDRRRALAVGIGAGIGTIFKTPIGGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTFDPLRLP
MYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLAPEILGTGYGWINLVEYEKFFTLYSPLIP
TIILLVILPFLKILGTSFSIGSGGSGGVFAPGLFIGAYIGASVGLLFHYLFPNIVPTIAPFAIIGMMSFFAGAGKVPLSV
LIMVTEMTSSLQLLPGAMIAVAISYLVSGNNTIYISQLPTRRDSPAHKAEYETPLMETVRVEKCELRDIKAYTDDKVGKA
IQIMLENNFMSLPVVNYDNRFLGVVYLRDLERANPEDSLGKYITRGSPSVSLTSTLEHALEVMATNKARWVAVVDKGKLL
GIVTYDGIIDAYKRELNAIKNS

Sequences:

>Translated_582_residues
MNLSSLPYFEKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTLNFIFHPGNYLLIPISTAIGG
LISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKIRWVVIPVKIIASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSP
EDRRRALAVGIGAGIGTIFKTPIGGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTFDPLRLP
MYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLAPEILGTGYGWINLVEYEKFFTLYSPLIP
TIILLVILPFLKILGTSFSIGSGGSGGVFAPGLFIGAYIGASVGLLFHYLFPNIVPTIAPFAIIGMMSFFAGAGKVPLSV
LIMVTEMTSSLQLLPGAMIAVAISYLVSGNNTIYISQLPTRRDSPAHKAEYETPLMETVRVEKCELRDIKAYTDDKVGKA
IQIMLENNFMSLPVVNYDNRFLGVVYLRDLERANPEDSLGKYITRGSPSVSLTSTLEHALEVMATNKARWVAVVDKGKLL
GIVTYDGIIDAYKRELNAIKNS
>Mature_582_residues
MNLSSLPYFEKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTLNFIFHPGNYLLIPISTAIGG
LISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKIRWVVIPVKIIASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSP
EDRRRALAVGIGAGIGTIFKTPIGGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTFDPLRLP
MYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLAPEILGTGYGWINLVEYEKFFTLYSPLIP
TIILLVILPFLKILGTSFSIGSGGSGGVFAPGLFIGAYIGASVGLLFHYLFPNIVPTIAPFAIIGMMSFFAGAGKVPLSV
LIMVTEMTSSLQLLPGAMIAVAISYLVSGNNTIYISQLPTRRDSPAHKAEYETPLMETVRVEKCELRDIKAYTDDKVGKA
IQIMLENNFMSLPVVNYDNRFLGVVYLRDLERANPEDSLGKYITRGSPSVSLTSTLEHALEVMATNKARWVAVVDKGKLL
GIVTYDGIIDAYKRELNAIKNS

Specific function: Selective chloride channel [C]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family [H]

Homologues:

Organism=Escherichia coli, GI1786350, Length=352, Percent_Identity=29.5454545454545, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87081943, Length=353, Percent_Identity=27.4787535410765, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 62900; Mature: 62900

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSSLPYFEKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
NFIFHPGNYLLIPISTAIGGLISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKIRWVVIPV
EEEEECCCEEEEEHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHEECCEEEEEEEEH
KIIASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRALAVGIGAGIGTIFK
HHHHHHHEECCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCHHHHHEEEEEECCCHHHHHC
TPIGGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTFDPLRLP
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
MYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLAPEILGTGY
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
GWINLVEYEKFFTLYSPLIPTIILLVILPFLKILGTSFSIGSGGSGGVFAPGLFIGAYIG
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
ASVGLLFHYLFPNIVPTIAPFAIIGMMSFFAGAGKVPLSVLIMVTEMTSSLQLLPGAMIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHH
VAISYLVSGNNTIYISQLPTRRDSPAHKAEYETPLMETVRVEKCELRDIKAYTDDKVGKA
HHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCE
IQIMLENNFMSLPVVNYDNRFLGVVYLRDLERANPEDSLGKYITRGSPSVSLTSTLEHAL
EEEEEECCCEECEEECCCCCEEEEHEEHHHHHCCCHHHHHHHHHCCCCCEEHHHHHHHHH
EVMATNKARWVAVVDKGKLLGIVTYDGIIDAYKRELNAIKNS
HHHHCCCCEEEEEEECCCEEEEEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLSSLPYFEKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
NFIFHPGNYLLIPISTAIGGLISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKIRWVVIPV
EEEEECCCEEEEEHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHEECCEEEEEEEEH
KIIASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRALAVGIGAGIGTIFK
HHHHHHHEECCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCHHHHHEEEEEECCCHHHHHC
TPIGGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTFDPLRLP
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
MYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLAPEILGTGY
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
GWINLVEYEKFFTLYSPLIPTIILLVILPFLKILGTSFSIGSGGSGGVFAPGLFIGAYIG
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
ASVGLLFHYLFPNIVPTIAPFAIIGMMSFFAGAGKVPLSVLIMVTEMTSSLQLLPGAMIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHH
VAISYLVSGNNTIYISQLPTRRDSPAHKAEYETPLMETVRVEKCELRDIKAYTDDKVGKA
HHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCE
IQIMLENNFMSLPVVNYDNRFLGVVYLRDLERANPEDSLGKYITRGSPSVSLTSTLEHAL
EEEEEECCCEECEEECCCCCEEEEHEEHHHHHCCCHHHHHHHHHCCCCCEEHHHHHHHHH
EVMATNKARWVAVVDKGKLLGIVTYDGIIDAYKRELNAIKNS
HHHHCCCCEEEEEEECCCEEEEEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Cl Ion [Periplasm] [C]

Specific reaction: Cl Ion [Periplasm] = Cl Ion [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]