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The map label for this gene is yphC [C]

Identifier: 227828413

GI number: 227828413

Start: 1975359

End: 1976441

Strand: Direct

Name: yphC [C]

Synonym: M1425_2156

Alternate gene names: 227828413

Gene position: 1975359-1976441 (Clockwise)

Preceding gene: 227828410

Following gene: 227828415

Centisome position: 75.72

GC content: 35.36

Gene sequence:

>1083_bases
ATGAAGGCATTAGTTGTTCATCCACCTAATAAAGGAGTAGAAGTTAAAGAGATAAGTGATATAGATCGATCATTAAATGG
AAATGAAGTTTTAATTAAGACAATAGCAAATGGTATTTGCGGAACTGATCGTGGTATTGTTTCTGGCCTACTTAAATTCT
CACGTCCACCCACAGAGAAAAACAGTCTAGTATTAGGACATGAAAATCTAGGTCAAGTAATCGATAAGGGATCCAATGTA
CAAGGTTTAAGTAAAGGGGATTATGTTGTTTCGATTGTTAGAAGGGGATGCGGAAAGTGTTCCAATTGCCTCGCCGGAAG
GCAAGATTTTTGTGAAACAGGTGAATTCGTGGAAGCTGGCATAAGAGGATTAGATGGCTTTATGAGAGAATTTTATATAG
ATAATACAAGTTATTTAGTTAGAATACCGTATGAAATAGTTGATATCGCAGTTTTGCTCGAACCTCTTTCCAATGTAGTA
AAGGCTTATAATGAGCTAATGTTAACGCAAAGGAGAATGATATGGTGGTGTAAGGATGGCAGTTATGGTTGTAAAAACGT
TGCAGTAGTGGGATCTGGGCCAATAGGTCTCCTTTTTTCGCTAATATTCTCCGTTCAAGGTTTTAACACATTCGTTTTAA
ATAAGAGAGATCCTTTTCCCACTGAGGCTGAGATTATAGAGAAGATTAACGCTAAATTTATAAACACTACTAAGGGTCAA
TTACCTTATGTAATAGATGTACTTATTGACACTTCTGGATATCCATCAGCATTTATTCCTTTAATGAATAAGTTAAACAA
AAACTCAGCTGTTATATTGTTCGGCACTACTGGTGGAGAGAAGTTTGAGGTAAATGCTGATTTAATAACATATCTTGTTG
AAAATAACGTTTTATTGTTTGGGAGCGTTAACGCTAGTAAGAGGGACTTCGAAGAGGGTGTAAATTACCTTACAATCTGG
AAATATAGATATCCAACTGTATTAAATAAAATGATAACTAGAGTAGTTAAGCCGGAGGAGGCCTCAGAAGTATTATATAC
AAAACCTAGAGGAGAAATAAAGACAATAATTTCATGGGTTTAA

Upstream 100 bases:

>100_bases
AGTTTTATATGTAAGATAACTGAACGTATATTTTAGATAATTGAAAGATTTATAGATCTCTCTTAGATTTAAAAATCTAG
CTGTAGCTATATTTCTATGT

Downstream 100 bases:

>100_bases
CTGACTCCTTAACGCTTCTATAGCTTTTTTAATTTCTTCCATTGAAGCTTCATCTTCTAATGTAGAGATATCTCCCACAG
CAGAGCCCATCATAACTGCT

Product: alcohol dehydrogenase GroES domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MKALVVHPPNKGVEVKEISDIDRSLNGNEVLIKTIANGICGTDRGIVSGLLKFSRPPTEKNSLVLGHENLGQVIDKGSNV
QGLSKGDYVVSIVRRGCGKCSNCLAGRQDFCETGEFVEAGIRGLDGFMREFYIDNTSYLVRIPYEIVDIAVLLEPLSNVV
KAYNELMLTQRRMIWWCKDGSYGCKNVAVVGSGPIGLLFSLIFSVQGFNTFVLNKRDPFPTEAEIIEKINAKFINTTKGQ
LPYVIDVLIDTSGYPSAFIPLMNKLNKNSAVILFGTTGGEKFEVNADLITYLVENNVLLFGSVNASKRDFEEGVNYLTIW
KYRYPTVLNKMITRVVKPEEASEVLYTKPRGEIKTIISWV

Sequences:

>Translated_360_residues
MKALVVHPPNKGVEVKEISDIDRSLNGNEVLIKTIANGICGTDRGIVSGLLKFSRPPTEKNSLVLGHENLGQVIDKGSNV
QGLSKGDYVVSIVRRGCGKCSNCLAGRQDFCETGEFVEAGIRGLDGFMREFYIDNTSYLVRIPYEIVDIAVLLEPLSNVV
KAYNELMLTQRRMIWWCKDGSYGCKNVAVVGSGPIGLLFSLIFSVQGFNTFVLNKRDPFPTEAEIIEKINAKFINTTKGQ
LPYVIDVLIDTSGYPSAFIPLMNKLNKNSAVILFGTTGGEKFEVNADLITYLVENNVLLFGSVNASKRDFEEGVNYLTIW
KYRYPTVLNKMITRVVKPEEASEVLYTKPRGEIKTIISWV
>Mature_360_residues
MKALVVHPPNKGVEVKEISDIDRSLNGNEVLIKTIANGICGTDRGIVSGLLKFSRPPTEKNSLVLGHENLGQVIDKGSNV
QGLSKGDYVVSIVRRGCGKCSNCLAGRQDFCETGEFVEAGIRGLDGFMREFYIDNTSYLVRIPYEIVDIAVLLEPLSNVV
KAYNELMLTQRRMIWWCKDGSYGCKNVAVVGSGPIGLLFSLIFSVQGFNTFVLNKRDPFPTEAEIIEKINAKFINTTKGQ
LPYVIDVLIDTSGYPSAFIPLMNKLNKNSAVILFGTTGGEKFEVNADLITYLVENNVLLFGSVNASKRDFEEGVNYLTIW
KYRYPTVLNKMITRVVKPEEASEVLYTKPRGEIKTIISWV

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790045, Length=286, Percent_Identity=25.8741258741259, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI226510992, Length=318, Percent_Identity=25.7861635220126, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787863, Length=314, Percent_Identity=25.796178343949, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI87081918, Length=155, Percent_Identity=30.3225806451613, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N [H]

EC number: =1.1.1.47 [H]

Molecular weight: Translated: 39985; Mature: 39985

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALVVHPPNKGVEVKEISDIDRSLNGNEVLIKTIANGICGTDRGIVSGLLKFSRPPTEK
CCEEEEECCCCCCCHHHHHHHHHCCCCCEEEHHHHHCCCCCCCHHHHHHHHHHCCCCCCC
NSLVLGHENLGQVIDKGSNVQGLSKGDYVVSIVRRGCGKCSNCLAGRQDFCETGEFVEAG
CCEEECCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCHHHHHCHHHHHHH
IRGLDGFMREFYIDNTSYLVRIPYEIVDIAVLLEPLSNVVKAYNELMLTQRRMIWWCKDG
HHHHHHHHHHHEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
SYGCKNVAVVGSGPIGLLFSLIFSVQGFNTFVLNKRDPFPTEAEIIEKINAKFINTTKGQ
CCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCEEECCCCC
LPYVIDVLIDTSGYPSAFIPLMNKLNKNSAVILFGTTGGEKFEVNADLITYLVENNVLLF
CCEEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEECHHHEEHEECCCEEEE
GSVNASKRDFEEGVNYLTIWKYRYPTVLNKMITRVVKPEEASEVLYTKPRGEIKTIISWV
ECCCCCHHHHHHCCCEEEEEEEECHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHCC
>Mature Secondary Structure
MKALVVHPPNKGVEVKEISDIDRSLNGNEVLIKTIANGICGTDRGIVSGLLKFSRPPTEK
CCEEEEECCCCCCCHHHHHHHHHCCCCCEEEHHHHHCCCCCCCHHHHHHHHHHCCCCCCC
NSLVLGHENLGQVIDKGSNVQGLSKGDYVVSIVRRGCGKCSNCLAGRQDFCETGEFVEAG
CCEEECCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCHHHHHCHHHHHHH
IRGLDGFMREFYIDNTSYLVRIPYEIVDIAVLLEPLSNVVKAYNELMLTQRRMIWWCKDG
HHHHHHHHHHHEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
SYGCKNVAVVGSGPIGLLFSLIFSVQGFNTFVLNKRDPFPTEAEIIEKINAKFINTTKGQ
CCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCEEECCCCC
LPYVIDVLIDTSGYPSAFIPLMNKLNKNSAVILFGTTGGEKFEVNADLITYLVENNVLLF
CCEEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEECHHHEEHEECCCEEEE
GSVNASKRDFEEGVNYLTIWKYRYPTVLNKMITRVVKPEEASEVLYTKPRGEIKTIISWV
ECCCCCHHHHHHCCCEEEEEEEECHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8436115; 11029001; 2803257 [H]