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The map label for this gene is speH [H]

Identifier: 227827813

GI number: 227827813

Start: 1438914

End: 1439282

Strand: Direct

Name: speH [H]

Synonym: M1425_1546

Alternate gene names: 227827813

Gene position: 1438914-1439282 (Clockwise)

Preceding gene: 227827810

Following gene: 227827814

Centisome position: 55.16

GC content: 36.31

Gene sequence:

>369_bases
ATGGGGGTAGAGTTAGCTTTTCCTAAAGTAGTAGGAAAGCAAGTATATGGAAGCTTATATGATTGCGATGAAAACGTTTT
AAAAGATACTAAAAGACTAGAGCAAATAATAAAGGAAGCAGCAGACGTGGGTAATATGAACATTCTTGACATAAAGTCAT
GGAAAATTGGGGAAGGTGTAAGTGTAGTGGCGATTATATTAGAAAGTCATATAACCATACATACGTGGCCGGAGTACAAA
TTCGCAACAGTTGATGTATACTCTTGTGGTCCACATACTAGCCCCTTAAAAGCATTTAATTATATAGTGGAAAAACTGGG
GGCTAAGAAATATACTATAAATGAGGCTGATAGATCATCGGAGTTCTAA

Upstream 100 bases:

>100_bases
AGTATTAATCAATTAGCATTAAAAACTTACTTTTAACCGCGATCAGGCGGAAATAAATTTATAAATGATAAAGTAGAGGG
GTTTAAGTGGGGGGTTGATG

Downstream 100 bases:

>100_bases
TAGTAGGCGGGGGATTAGCTGGGCTATTATTGGCATATAATATTCTGGATTCTAATCCAATAGTTTTTGATAGAAGACGT
TTTCCGGGTAAGAAGTGTAC

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MGVELAFPKVVGKQVYGSLYDCDENVLKDTKRLEQIIKEAADVGNMNILDIKSWKIGEGVSVVAIILESHITIHTWPEYK
FATVDVYSCGPHTSPLKAFNYIVEKLGAKKYTINEADRSSEF

Sequences:

>Translated_122_residues
MGVELAFPKVVGKQVYGSLYDCDENVLKDTKRLEQIIKEAADVGNMNILDIKSWKIGEGVSVVAIILESHITIHTWPEYK
FATVDVYSCGPHTSPLKAFNYIVEKLGAKKYTINEADRSSEF
>Mature_121_residues
GVELAFPKVVGKQVYGSLYDCDENVLKDTKRLEQIIKEAADVGNMNILDIKSWKIGEGVSVVAIILESHITIHTWPEYKF
ATVDVYSCGPHTSPLKAFNYIVEKLGAKKYTINEADRSSEF

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine. Has no arginine decarboxylase (ArgDC) act

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 13669; Mature: 13538

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVELAFPKVVGKQVYGSLYDCDENVLKDTKRLEQIIKEAADVGNMNILDIKSWKIGEGV
CCCCCCCHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCH
SVVAIILESHITIHTWPEYKFATVDVYSCGPHTSPLKAFNYIVEKLGAKKYTINEADRSS
HHHHHHHHCCEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEECCCCCCCC
EF
CC
>Mature Secondary Structure 
GVELAFPKVVGKQVYGSLYDCDENVLKDTKRLEQIIKEAADVGNMNILDIKSWKIGEGV
CCCCCCHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCH
SVVAIILESHITIHTWPEYKFATVDVYSCGPHTSPLKAFNYIVEKLGAKKYTINEADRSS
HHHHHHHHCCEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEECCCCCCCC
EF
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10701121; 11427726; 1649051 [H]