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The map label for this gene is yvqK [H]

Identifier: 227827810

GI number: 227827810

Start: 1437048

End: 1437572

Strand: Direct

Name: yvqK [H]

Synonym: M1425_1543

Alternate gene names: 227827810

Gene position: 1437048-1437572 (Clockwise)

Preceding gene: 227827808

Following gene: 227827813

Centisome position: 55.08

GC content: 35.05

Gene sequence:

>525_bases
ATGTTCACCAGAACTGGAGACGATGGAAATACCAATGTAGTATCTAAGAGAGTAGGAAAAGATTCACCTCTAGTAAATCT
ATTAGGGGATATAGATGAGCTTAACTCCTTCATAGGTCTTGCATTAACAAAAATAGAATGGGAAGATATGCAAAATGATC
TCATGCGTATTCAAACTGAGTTGTTTGTATTAGGTGAGGAGATTATTCACGATAGAGGTAGAATAAATGAGGAGACTGTA
AAGTGGTTAGAGAGTAGAACTGTCGAATATAGGAAAGAAAGTGGTCCTGTAAGGTTATTTGTAATACCAGGTGGTTCTGA
GGAGGCTTCATATTTGCATGTAGCAAGAAGCGTTTCTAGAAGAGTTGAAAGAAATGCAGTAGCTTACTCTAAAGAACTGA
ATTTCAATAAATGGATAATTGTTTATCTGAACAGATTATCTTCTTTACTATTTTCCATGGCCATAGTAGCAAATAAGAGG
AAAAACGTAAAGGAGAGACTTTATGATATAGGCAAGTATTTTTGA

Upstream 100 bases:

>100_bases
GTGAGCAACGTTATTCAAAAAGTCAATAAAGTCCCTATACTGTGAGCTTATTTTACTTCACCAAAAATGATATAGCTAGG
TCTTTTTTAAATATTAACTA

Downstream 100 bases:

>100_bases
TATTCTTGAGGCATTAAACCAGATCTGATTAGTAATTCACAATTTTTACATATCGTTCTTCCGGGCGTAGTGGGTTCTCC
ACATATTATACAATTAGGTA

Product: ATP--cobalamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MFTRTGDDGNTNVVSKRVGKDSPLVNLLGDIDELNSFIGLALTKIEWEDMQNDLMRIQTELFVLGEEIIHDRGRINEETV
KWLESRTVEYRKESGPVRLFVIPGGSEEASYLHVARSVSRRVERNAVAYSKELNFNKWIIVYLNRLSSLLFSMAIVANKR
KNVKERLYDIGKYF

Sequences:

>Translated_174_residues
MFTRTGDDGNTNVVSKRVGKDSPLVNLLGDIDELNSFIGLALTKIEWEDMQNDLMRIQTELFVLGEEIIHDRGRINEETV
KWLESRTVEYRKESGPVRLFVIPGGSEEASYLHVARSVSRRVERNAVAYSKELNFNKWIIVYLNRLSSLLFSMAIVANKR
KNVKERLYDIGKYF
>Mature_174_residues
MFTRTGDDGNTNVVSKRVGKDSPLVNLLGDIDELNSFIGLALTKIEWEDMQNDLMRIQTELFVLGEEIIHDRGRINEETV
KWLESRTVEYRKESGPVRLFVIPGGSEEASYLHVARSVSRRVERNAVAYSKELNFNKWIIVYLNRLSSLLFSMAIVANKR
KNVKERLYDIGKYF

Specific function: Unknown

COG id: COG2096

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI16418349, Length=181, Percent_Identity=28.7292817679558, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115534154, Length=179, Percent_Identity=26.8156424581006, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017858
- InterPro:   IPR002779
- InterPro:   IPR016030
- ProDom:   PD007457 [H]

Pfam domain/function: PF01923 Cob_adeno_trans [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 20102; Mature: 20102

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTRTGDDGNTNVVSKRVGKDSPLVNLLGDIDELNSFIGLALTKIEWEDMQNDLMRIQTE
CCCCCCCCCCCHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVLGEEIIHDRGRINEETVKWLESRTVEYRKESGPVRLFVIPGGSEEASYLHVARSVSR
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHH
RVERNAVAYSKELNFNKWIIVYLNRLSSLLFSMAIVANKRKNVKERLYDIGKYF
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFTRTGDDGNTNVVSKRVGKDSPLVNLLGDIDELNSFIGLALTKIEWEDMQNDLMRIQTE
CCCCCCCCCCCHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVLGEEIIHDRGRINEETVKWLESRTVEYRKESGPVRLFVIPGGSEEASYLHVARSVSR
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHH
RVERNAVAYSKELNFNKWIIVYLNRLSSLLFSMAIVANKRKNVKERLYDIGKYF
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]