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The map label for this gene is ttuD [H]

Identifier: 227827740

GI number: 227827740

Start: 1376660

End: 1377862

Strand: Direct

Name: ttuD [H]

Synonym: M1425_1471

Alternate gene names: 227827740

Gene position: 1376660-1377862 (Clockwise)

Preceding gene: 227827739

Following gene: 227827742

Centisome position: 52.77

GC content: 35.49

Gene sequence:

>1203_bases
ATGGATATCGTTGAAAAGATTTTAGAGTATTCAAATCCCTATAATGTTTTGCAAGAGAAAGTTAAGATAAAGGATAATTC
GCTTTTATTTAATAACGAAAATATCCCATTTAACAAACCTATACTGATTTCAGTAGGGAAGGCCTCTTTGCCCATGGCGC
GATTCTTTAGTGAGAGGATTGAATTAAAGGCTAAATTAATAGTAACACCGAAGGGTACTAAAGGTAACGAGAATAACGTT
ATAGAAGCTGGTCATCCCTTGCCAGATGAGAACAGTATAGAGGCTGGGAAAAGGATAATAGAGCTATTAACTACTGAGGA
CTACGATTTAGTTATATTTGCAATTTCTGGGGGCGCGTCAGCATTAGTTGAATATTCTGAAATATCCTTAGATGAGCTGA
GAATGATTACCAAGAATCTTGTTATCTCTGGAATAGGAATTAATAAAATAAATATAGTAAGGAAGCATTTATCTAAGATA
AAAGGGGGTAAGATACTAGAATATATAAAAGATAAAATCCCTGTAGTGTCATTTATTGTTAGTGATGTTCCAGGTAATGA
CATAAGTAGTATTGGAAGTGGTCTTACTAGTATTGATACCTCTACTAACGAGAATGCATTAGAAATTTTAAAAGATATAG
GATTAGAAAAATACTCCAAGTATCTGACTGAGACCCCTAAGAGTTTCTCTAGAATTGTGAAAAATTACATAATTCTAGAT
AACATGGAGGTACTTAAGAAGCTCGCAAATATTCTGGACAACTCCTTCATTCTTACTTCTGAAATCAGAGGAGAGGCAAG
AGATGTGGGAGCTATTATTGCTTCAATTTATAATTCGTCAGAGAACTATAATGTACCTTTAAGGAGACCTTACTATTTAT
TACTTGGTGGGGAGCCAGAAGTTACAATTCAAGGAAAGGCAGGGAAGGGTGGAAGAAATGGAGAGGTCTGCCTATCCTTC
CTCAAATACGCTAAAAAAGGAAATAGATTTGAACTATTAGGTTTCGCTACTGATGGAGTTGACGGTAACTCAGAATATGC
TGGTTGTAAAGTCAATTCGGACATGAAAATAGCAGAGGAGGAGATAGATGCTGCATTAGAGACTCACAATAGTTATGGCT
TGCTAGAAAACTATGGAGGGACTATAAAAACTGGCTATACTCACACTAACGTGAATAATATTTATGTGTTAAGGGCTCCT
TGA

Upstream 100 bases:

>100_bases
TAAATCATAAGCCCAAGGGAATTTACTATGATCTAAGTAAAGAAGGAAAAAAGATTGCATCGTTACTATATAAGGAATAT
AAAAGGGAGAATGGATAATT

Downstream 100 bases:

>100_bases
GTTCTTATCTTCTTTTGTAACATTAATACTGCCCTAGCGACAGCCTCTGGCCTTATTGGACATCCAGGAACGTATAAATC
AACTGGAATTCCAAGGTCTG

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MDIVEKILEYSNPYNVLQEKVKIKDNSLLFNNENIPFNKPILISVGKASLPMARFFSERIELKAKLIVTPKGTKGNENNV
IEAGHPLPDENSIEAGKRIIELLTTEDYDLVIFAISGGASALVEYSEISLDELRMITKNLVISGIGINKINIVRKHLSKI
KGGKILEYIKDKIPVVSFIVSDVPGNDISSIGSGLTSIDTSTNENALEILKDIGLEKYSKYLTETPKSFSRIVKNYIILD
NMEVLKKLANILDNSFILTSEIRGEARDVGAIIASIYNSSENYNVPLRRPYYLLLGGEPEVTIQGKAGKGGRNGEVCLSF
LKYAKKGNRFELLGFATDGVDGNSEYAGCKVNSDMKIAEEEIDAALETHNSYGLLENYGGTIKTGYTHTNVNNIYVLRAP

Sequences:

>Translated_400_residues
MDIVEKILEYSNPYNVLQEKVKIKDNSLLFNNENIPFNKPILISVGKASLPMARFFSERIELKAKLIVTPKGTKGNENNV
IEAGHPLPDENSIEAGKRIIELLTTEDYDLVIFAISGGASALVEYSEISLDELRMITKNLVISGIGINKINIVRKHLSKI
KGGKILEYIKDKIPVVSFIVSDVPGNDISSIGSGLTSIDTSTNENALEILKDIGLEKYSKYLTETPKSFSRIVKNYIILD
NMEVLKKLANILDNSFILTSEIRGEARDVGAIIASIYNSSENYNVPLRRPYYLLLGGEPEVTIQGKAGKGGRNGEVCLSF
LKYAKKGNRFELLGFATDGVDGNSEYAGCKVNSDMKIAEEEIDAALETHNSYGLLENYGGTIKTGYTHTNVNNIYVLRAP
>Mature_400_residues
MDIVEKILEYSNPYNVLQEKVKIKDNSLLFNNENIPFNKPILISVGKASLPMARFFSERIELKAKLIVTPKGTKGNENNV
IEAGHPLPDENSIEAGKRIIELLTTEDYDLVIFAISGGASALVEYSEISLDELRMITKNLVISGIGINKINIVRKHLSKI
KGGKILEYIKDKIPVVSFIVSDVPGNDISSIGSGLTSIDTSTNENALEILKDIGLEKYSKYLTETPKSFSRIVKNYIILD
NMEVLKKLANILDNSFILTSEIRGEARDVGAIIASIYNSSENYNVPLRRPYYLLLGGEPEVTIQGKAGKGGRNGEVCLSF
LKYAKKGNRFELLGFATDGVDGNSEYAGCKVNSDMKIAEEEIDAALETHNSYGLLENYGGTIKTGYTHTNVNNIYVLRAP

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=474, Percent_Identity=26.3713080168776, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI193205461, Length=448, Percent_Identity=29.6875, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI19920578, Length=381, Percent_Identity=25.4593175853018, Blast_Score=85, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 44109; Mature: 44109

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIVEKILEYSNPYNVLQEKVKIKDNSLLFNNENIPFNKPILISVGKASLPMARFFSERI
CCHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHH
ELKAKLIVTPKGTKGNENNVIEAGHPLPDENSIEAGKRIIELLTTEDYDLVIFAISGGAS
CEEEEEEEECCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCH
ALVEYSEISLDELRMITKNLVISGIGINKINIVRKHLSKIKGGKILEYIKDKIPVVSFIV
HEEEHHHCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHH
SDVPGNDISSIGSGLTSIDTSTNENALEILKDIGLEKYSKYLTETPKSFSRIVKNYIILD
HCCCCCCHHHHCCCCEECCCCCCCHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHEEEC
NMEVLKKLANILDNSFILTSEIRGEARDVGAIIASIYNSSENYNVPLRRPYYLLLGGEPE
CHHHHHHHHHHHCCCEEEEHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCC
VTIQGKAGKGGRNGEVCLSFLKYAKKGNRFELLGFATDGVDGNSEYAGCKVNSDMKIAEE
EEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCEEECCCCHHHHH
EIDAALETHNSYGLLENYGGTIKTGYTHTNVNNIYVLRAP
HHHHHHHCCCCCCCHHHCCCEEECCEEECCCCEEEEEECC
>Mature Secondary Structure
MDIVEKILEYSNPYNVLQEKVKIKDNSLLFNNENIPFNKPILISVGKASLPMARFFSERI
CCHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHH
ELKAKLIVTPKGTKGNENNVIEAGHPLPDENSIEAGKRIIELLTTEDYDLVIFAISGGAS
CEEEEEEEECCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCH
ALVEYSEISLDELRMITKNLVISGIGINKINIVRKHLSKIKGGKILEYIKDKIPVVSFIV
HEEEHHHCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHH
SDVPGNDISSIGSGLTSIDTSTNENALEILKDIGLEKYSKYLTETPKSFSRIVKNYIILD
HCCCCCCHHHHCCCCEECCCCCCCHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHEEEC
NMEVLKKLANILDNSFILTSEIRGEARDVGAIIASIYNSSENYNVPLRRPYYLLLGGEPE
CHHHHHHHHHHHCCCEEEEHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCC
VTIQGKAGKGGRNGEVCLSFLKYAKKGNRFELLGFATDGVDGNSEYAGCKVNSDMKIAEE
EEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCEEECCCCHHHHH
EIDAALETHNSYGLLENYGGTIKTGYTHTNVNNIYVLRAP
HHHHHHHCCCCCCCHHHCCCEEECCEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8672817 [H]